PubRank

Mary B Goldring

Author PubWeight™ 92.67‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Osteoarthritis: a disease of the joint as an organ. Arthritis Rheum 2012 4.28
2 The role of cytokines in cartilage matrix degeneration in osteoarthritis. Clin Orthop Relat Res 2004 2.92
3 Increased expression of the collagen receptor discoidin domain receptor 2 in articular cartilage as a key event in the pathogenesis of osteoarthritis. Arthritis Rheum 2007 2.07
4 NF-kappaB signaling: multiple angles to target OA. Curr Drug Targets 2010 1.89
5 Loss of methylation in CpG sites in the NF-κB enhancer elements of inducible nitric oxide synthase is responsible for gene induction in human articular chondrocytes. Arthritis Rheum 2013 1.70
6 NF-kappa B-mediated repression of growth arrest- and DNA-damage-inducible proteins 45alpha and gamma is essential for cancer cell survival. Proc Natl Acad Sci U S A 2004 1.66
7 Production of endogenous antibiotics in articular cartilage. Arthritis Rheum 2004 1.55
8 Activation of the discoidin domain receptor 2 induces expression of matrix metalloproteinase 13 associated with osteoarthritis in mice. J Biol Chem 2004 1.53
9 DNA demethylation at specific CpG sites in the IL1B promoter in response to inflammatory cytokines in human articular chondrocytes. Arthritis Rheum 2009 1.46
10 CITED2-mediated regulation of MMP-1 and MMP-13 in human chondrocytes under flow shear. J Biol Chem 2003 1.41
11 Cartilage oligomeric matrix protein/thrombospondin 5 supports chondrocyte attachment through interaction with integrins. J Biol Chem 2005 1.37
12 A misplaced lncRNA causes brachydactyly in humans. J Clin Invest 2012 1.36
13 Differential expression of GADD45beta in normal and osteoarthritic cartilage: potential role in homeostasis of articular chondrocytes. Arthritis Rheum 2008 1.33
14 Homeostatic mechanisms in articular cartilage and role of inflammation in osteoarthritis. Curr Rheumatol Rep 2013 1.31
15 Eating bone or adding it: the Wnt pathway decides. Nat Med 2007 1.30
16 A novel role for GADD45beta as a mediator of MMP-13 gene expression during chondrocyte terminal differentiation. J Biol Chem 2005 1.30
17 Divergent responses of chondrocytes and endothelial cells to shear stress: cross-talk among COX-2, the phase 2 response, and apoptosis. Proc Natl Acad Sci U S A 2005 1.28
18 Vascular endothelial growth factor (VEGF) induces matrix metalloproteinase expression in immortalized chondrocytes. J Pathol 2004 1.25
19 In vivo cyclic compression causes cartilage degeneration and subchondral bone changes in mouse tibiae. Arthritis Rheum 2013 1.24
20 Egr-1 mediates transcriptional repression of COL2A1 promoter activity by interleukin-1beta. J Biol Chem 2003 1.22
21 Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1β (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites. J Biol Chem 2013 1.22
22 WISP3-dependent regulation of type II collagen and aggrecan production in chondrocytes. Arthritis Rheum 2004 1.21
23 Up-regulation of microsomal prostaglandin E synthase 1 in osteoarthritic human cartilage: critical roles of the ERK-1/2 and p38 signaling pathways. Arthritis Rheum 2004 1.16
24 Selection of reliable reference genes for qPCR studies on chondroprotective action. BMC Mol Biol 2007 1.16
25 The epigenetic effect of glucosamine and a nuclear factor-kappa B (NF-kB) inhibitor on primary human chondrocytes--implications for osteoarthritis. Biochem Biophys Res Commun 2011 1.15
26 A cis-regulatory site downregulates PTHLH in translocation t(8;12)(q13;p11.2) and leads to Brachydactyly Type E. Hum Mol Genet 2009 1.13
27 Physiological loading of joints prevents cartilage degradation through CITED2. FASEB J 2010 1.12
28 Bone and cartilage in osteoarthritis: is what's best for one good or bad for the other? Arthritis Res Ther 2010 1.11
29 Divergent stress responses to IL-1beta, nitric oxide, and tunicamycin by chondrocytes. J Cell Physiol 2005 1.08
30 Responses to the proinflammatory cytokines interleukin-1 and tumor necrosis factor alpha in cells derived from rheumatoid synovium and other joint tissues involve nuclear factor kappaB-mediated induction of the Ets transcription factor ESE-1. Arthritis Rheum 2003 1.08
31 ESE-1 is a potent repressor of type II collagen gene (COL2A1) transcription in human chondrocytes. J Cell Physiol 2008 1.06
32 The Ets transcription factor ESE-1 mediates induction of the COX-2 gene by LPS in monocytes. FEBS J 2005 1.06
33 The homeotic protein Six3 is a coactivator of the nuclear receptor NOR-1 and a corepressor of the fusion protein EWS/NOR-1 in human extraskeletal myxoid chondrosarcomas. Cancer Res 2003 1.05
34 E74-like factor 3 (ELF3) impacts on matrix metalloproteinase 13 (MMP13) transcriptional control in articular chondrocytes under proinflammatory stress. J Biol Chem 2011 1.04
35 Cells of the synovium in rheumatoid arthritis. Chondrocytes. Arthritis Res Ther 2007 1.03
36 Suppressors of cytokine signalling (SOCS) are reduced in osteoarthritis. Biochem Biophys Res Commun 2011 1.03
37 Endostatin/collagen XVIII--an inhibitor of angiogenesis--is expressed in cartilage and fibrocartilage. Matrix Biol 2004 1.03
38 Differentiation regulates interleukin-1beta-induced cyclo-oxygenase-2 in human articular chondrocytes: role of p38 mitogen-activated protein kinase. Biochem J 2002 1.02
39 GADD45beta enhances Col10a1 transcription via the MTK1/MKK3/6/p38 axis and activation of C/EBPbeta-TAD4 in terminally differentiating chondrocytes. J Biol Chem 2010 1.02
40 ESE-1 is a novel transcriptional mediator of angiopoietin-1 expression in the setting of inflammation. J Biol Chem 2004 1.01
41 Transcriptional and post-transcriptional regulation of iNOS expression in human chondrocytes. Biochem Pharmacol 2009 1.00
42 Chondrogenesis, joint formation, and articular cartilage regeneration. J Cell Biochem 2009 1.00
43 Proteomic analysis of synovial fluid from the osteoarthritic knee: comparison with transcriptome analyses of joint tissues. Arthritis Rheum 2013 1.00
44 Pulsed electromagnetic fields increased the anti-inflammatory effect of A₂A and A₃ adenosine receptors in human T/C-28a2 chondrocytes and hFOB 1.19 osteoblasts. PLoS One 2013 1.00
45 The TATA-containing core promoter of the type II collagen gene (COL2A1) is the target of interferon-gamma-mediated inhibition in human chondrocytes: requirement for Stat1 alpha, Jak1 and Jak2. Biochem J 2003 0.96
46 Involvement of p38 MAPK in regulation of MMP13 mRNA in chondrocytes in response to surviving stress to endoplasmic reticulum. Arch Oral Biol 2008 0.95
47 Inhibitors of mitogen-activated protein kinases downregulate COX-2 expression in human chondrocytes. Mediators Inflamm 2005 0.95
48 Association of reduced type IX collagen gene expression in human osteoarthritic chondrocytes with epigenetic silencing by DNA hypermethylation. Arthritis Rheumatol 2014 0.93
49 Human beta-defensin 3 mediates tissue remodeling processes in articular cartilage by increasing levels of metalloproteinases and reducing levels of their endogenous inhibitors. Arthritis Rheum 2005 0.92
50 Anti-inflammatory activity of an ethanolic Caesalpinia sappan extract in human chondrocytes and macrophages. J Ethnopharmacol 2011 0.92
51 Prolonged application of high fluid shear to chondrocytes recapitulates gene expression profiles associated with osteoarthritis. PLoS One 2010 0.91
52 Reactive oxygen species induce expression of vascular endothelial growth factor in chondrocytes and human articular cartilage explants. Arthritis Res Ther 2006 0.91
53 Production of interleukin-1 receptor antagonist by human articular chondrocytes. Arthritis Res 2002 0.90
54 C-28/I2 and T/C-28a2 chondrocytes as well as human primary articular chondrocytes express sex hormone and insulin receptors--Useful cells in study of cartilage metabolism. Ann Anat 2010 0.90
55 Dual regulation of metalloproteinase expression in chondrocytes by Wnt-1-inducible signaling pathway protein 3/CCN6. Arthritis Rheum 2012 0.89
56 Association of joint space narrowing with impairment of physical function and work ability in patients with early rheumatoid arthritis: protection beyond disease control by adalimumab plus methotrexate. Ann Rheum Dis 2012 0.89
57 T cell-specific expression of the murine CD3delta promoter. J Biol Chem 2002 0.88
58 Senescence of chondrocytes in aging articular cartilage: GADD45β mediates p21 expression in association with C/EBPβ in senescence-accelerated mice. Pathol Res Pract 2011 0.87
59 Characterization and regulation of ADAMTS-16. Matrix Biol 2009 0.87
60 Relationship between cartilage stiffness and dGEMRIC index: correlation and prediction. J Orthop Res 2007 0.87
61 ADAM17 controls endochondral ossification by regulating terminal differentiation of chondrocytes. Mol Cell Biol 2013 0.87
62 Matrilin-3 induction of IL-1 receptor antagonist is required for up-regulating collagen II and aggrecan and down-regulating ADAMTS-5 gene expression. Arthritis Res Ther 2012 0.86
63 Intact pericellular matrix of articular cartilage is required for unactivated discoidin domain receptor 2 in the mouse model. Am J Pathol 2011 0.85
64 Polyamine depletion inhibits NF-kappaB binding to DNA and interleukin-8 production in human chondrocytes stimulated by tumor necrosis factor-alpha. J Cell Physiol 2005 0.85
65 Caesalpinia sappan extract inhibits IL1β-mediated overexpression of matrix metalloproteinases in human chondrocytes. Genes Nutr 2011 0.84
66 Trefoil factor 3 is induced during degenerative and inflammatory joint disease, activates matrix metalloproteinases, and enhances apoptosis of articular cartilage chondrocytes. Arthritis Rheum 2010 0.84
67 Polyamine depletion inhibits apoptosis following blocking of survival pathways in human chondrocytes stimulated by tumor necrosis factor-alpha. J Cell Physiol 2006 0.83
68 Identification of α2-macroglobulin as a master inhibitor of cartilage-degrading factors that attenuates the progression of posttraumatic osteoarthritis. Arthritis Rheumatol 2014 0.83
69 Endoglin is expressed on human chondrocytes and forms a heteromeric complex with betaglycan in a ligand and type II TGFbeta receptor independent manner. J Bone Miner Res 2003 0.82
70 Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse post-traumatic osteoarthritis model. Arthritis Res Ther 2014 0.82
71 Phenotypic characterization of human chondrocyte cell line C-20/A4: a comparison between monolayer and alginate suspension culture. Cells Tissues Organs 2004 0.81
72 The link between structural damage and pain in a genetic model of osteoarthritis and intervertebral disc degeneration: a joint misadventure. Arthritis Rheum 2009 0.81
73 Exploring the role of 5' alternative splicing and of the 3'-untranslated region of cathepsin B mRNA. Biol Chem 2003 0.80
74 VEGF expression in adult permanent thyroid cartilage: implications for lack of cartilage ossification. Bone 2004 0.79
75 The proinflammatory cytokines interleukin-1α and tumor necrosis factor α promote the expression and secretion of proteolytically active cathepsin S from human chondrocytes. Biol Chem 2013 0.79
76 Mouse models of osteoarthritis: surgical model of posttraumatic osteoarthritis induced by destabilization of the medial meniscus. Methods Mol Biol 2015 0.79
77 Cathepsin B expression and down-regulation by gene silencing and antisense DNA in human chondrocytes. Biochem J 2002 0.79
78 Lentiviral shRNA knock-down of ADAMTS-5 and -9 restores matrix deposition in 3D chondrocyte culture. J Tissue Eng Regen Med 2010 0.78
79 IKKα/CHUK regulates extracellular matrix remodeling independent of its kinase activity to facilitate articular chondrocyte differentiation. PLoS One 2013 0.78
80 Human chondrocyte cultures as models of cartilage-specific gene regulation. Methods Mol Biol 2012 0.78
81 Are bone morphogenetic proteins effective inducers of cartilage repair? Ex vivo transduction of muscle-derived stem cells. Arthritis Rheum 2006 0.77
82 Light-activated gene transduction enhances adeno-associated virus vector-mediated gene expression in human articular chondrocytes. Arthritis Rheum 2002 0.77
83 The development of anticytokine therapeutics for rheumatic diseases. Arthritis Rheum 2008 0.76
84 Lack of ADAM10 in endothelial cells affects osteoclasts at the chondro-osseus junction. J Orthop Res 2013 0.76
85 The effect of paraformaldehyde fixation on the delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) measurement. J Orthop Res 2009 0.75
86 Do mouse models reflect the diversity of osteoarthritis in humans? Arthritis Rheum 2012 0.75
87 Tribute to Stephen M. Krane. J Bone Miner Res 2015 0.75