PubRank

Lothar Willmitzer

Author PubWeight™ 121.21‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 GMD@CSB.DB: the Golm Metabolome Database. Bioinformatics 2004 7.33
2 Gas chromatography mass spectrometry-based metabolite profiling in plants. Nat Protoc 2006 6.33
3 Comprehensive metabolic profiling and phenotyping of interspecific introgression lines for tomato improvement. Nat Biotechnol 2006 4.47
4 Metabolite profiling: from diagnostics to systems biology. Nat Rev Mol Cell Biol 2004 3.31
5 GC-MS libraries for the rapid identification of metabolites in complex biological samples. FEBS Lett 2005 3.29
6 Genomic and metabolic prediction of complex heterotic traits in hybrid maize. Nat Genet 2012 2.70
7 The metabolic signature related to high plant growth rate in Arabidopsis thaliana. Proc Natl Acad Sci U S A 2007 2.44
8 Metabolomic and transcriptomic stress response of Escherichia coli. Mol Syst Biol 2010 2.04
9 13C isotope-labeled metabolomes allowing for improved compound annotation and relative quantification in liquid chromatography-mass spectrometry-based metabolomic research. Anal Chem 2009 1.85
10 Parallel analysis of transcript and metabolic profiles: a new approach in systems biology. EMBO Rep 2003 1.76
11 Identification of metabolic and biomass QTL in Arabidopsis thaliana in a parallel analysis of RIL and IL populations. Plant J 2007 1.74
12 Synthetic lethal metabolic targeting of cellular senescence in cancer therapy. Nature 2013 1.66
13 Genome-wide association mapping of leaf metabolic profiles for dissecting complex traits in maize. Proc Natl Acad Sci U S A 2012 1.61
14 Recommendations for reporting metabolite data. Plant Cell 2011 1.61
15 Probing the reproducibility of leaf growth and molecular phenotypes: a comparison of three Arabidopsis accessions cultivated in ten laboratories. Plant Physiol 2010 1.46
16 TargetSearch--a Bioconductor package for the efficient preprocessing of GC-MS metabolite profiling data. BMC Bioinformatics 2009 1.40
17 Kinetics of labelling of organic and amino acids in potato tubers by gas chromatography-mass spectrometry following incubation in (13)C labelled isotopes. Plant J 2004 1.37
18 Elemental formula annotation of polar and lipophilic metabolites using (13) C, (15) N and (34) S isotope labelling, in combination with high-resolution mass spectrometry. Plant J 2011 1.35
19 High-density kinetic analysis of the metabolomic and transcriptomic response of Arabidopsis to eight environmental conditions. Plant J 2011 1.34
20 Integrative gene-metabolite network with implemented causality deciphers informational fluxes of sulphur stress response. J Exp Bot 2005 1.31
21 Starch content and yield increase as a result of altering adenylate pools in transgenic plants. Nat Biotechnol 2002 1.30
22 RNA interference of LIN5 in tomato confirms its role in controlling Brix content, uncovers the influence of sugars on the levels of fruit hormones, and demonstrates the importance of sucrose cleavage for normal fruit development and fertility. Plant Physiol 2009 1.24
23 Interaction with diurnal and circadian regulation results in dynamic metabolic and transcriptional changes during cold acclimation in Arabidopsis. PLoS One 2010 1.24
24 Metabolic profiling reveals key metabolic features of renal cell carcinoma. J Cell Mol Med 2011 1.23
25 QTL analysis of early stage heterosis for biomass in Arabidopsis. Theor Appl Genet 2010 1.20
26 High-resolution direct infusion-based mass spectrometry in combination with whole 13C metabolome isotope labeling allows unambiguous assignment of chemical sum formulas. Anal Chem 2008 1.18
27 Antisense repression of cytosolic phosphoglucomutase in potato (Solanum tuberosum) results in severe growth retardation, reduction in tuber number and altered carbon metabolism. Planta 2002 1.16
28 Overexpression of the sucrose transporter SoSUT1 in potato results in alterations in leaf carbon partitioning and in tuber metabolism but has little impact on tuber morphology. Planta 2003 1.16
29 Production of human papillomavirus type 16 virus-like particles in transgenic plants. J Virol 2003 1.15
30 Differential remodeling of the lipidome during cold acclimation in natural accessions of Arabidopsis thaliana. Plant J 2012 1.14
31 The RON1/FRY1/SAL1 gene is required for leaf morphogenesis and venation patterning in Arabidopsis. Plant Physiol 2009 1.12
32 Analysis of the transient increase in cytosolic Ca2+ during the action potential of higher plants with high temporal resolution: requirement of Ca2+ transients for induction of jasmonic acid biosynthesis and PINII gene expression. Plant Cell Physiol 2004 1.12
33 Identification of heterotic metabolite QTL in Arabidopsis thaliana RIL and IL populations. Plant J 2009 1.11
34 High-resolution plant metabolomics: from mass spectral features to metabolites and from whole-cell analysis to subcellular metabolite distributions. Plant J 2012 1.11
35 Heterosis manifestation during early Arabidopsis seedling development is characterized by intermediate gene expression and enhanced metabolic activity in the hybrids. Plant J 2012 1.09
36 Rapid metabolic evolution in human prefrontal cortex. Proc Natl Acad Sci U S A 2011 1.09
37 Additional role of O-acetylserine as a sulfur status-independent regulator during plant growth. Plant J 2012 1.04
38 Analysis of short-term changes in the Arabidopsis thaliana glycerolipidome in response to temperature and light. Plant J 2011 1.04
39 Systemic analysis of inducible target of rapamycin mutants reveal a general metabolic switch controlling growth in Arabidopsis thaliana. Plant J 2013 1.04
40 Carbon assimilation and metabolism in potato leaves deficient in plastidial phosphoglucomutase. Planta 2002 1.03
41 De novo amino acid biosynthesis in potato tubers is regulated by sucrose levels. Plant Physiol 2003 1.03
42 Combined transcript and metabolite profiling of Arabidopsis grown under widely variant growth conditions facilitates the identification of novel metabolite-mediated regulation of gene expression. Plant Physiol 2010 1.02
43 The expression of an extensin-like protein correlates with cellular tip growth in tomato. Plant Physiol 2002 1.01
44 Sucrose to starch: a transition in molecular plant physiology. Trends Plant Sci 2002 1.01
45 Global mRNA changes in microarray experiments. Nat Biotechnol 2008 1.00
46 Toward the storage metabolome: profiling the barley vacuole. Plant Physiol 2011 1.00
47 The nematode resistance allele at the rhg1 locus alters the proteome and primary metabolism of soybean roots. Plant Physiol 2009 1.00
48 Assessment of sampling strategies for gas chromatography-mass spectrometry (GC-MS) based metabolomics of cyanobacteria. J Chromatogr B Analyt Technol Biomed Life Sci 2009 1.00
49 A topological map of the compartmentalized Arabidopsis thaliana leaf metabolome. PLoS One 2011 0.99
50 Trichoderma-plant root colonization: escaping early plant defense responses and activation of the antioxidant machinery for saline stress tolerance. PLoS Pathog 2013 0.99
51 Transcript and metabolite analysis of the Trichoderma-induced systemic resistance response to Pseudomonas syringae in Arabidopsis thaliana. Microbiology 2011 0.99
52 Temporally regulated expression of a yeast invertase in potato tubers allows dissection of the complex metabolic phenotype obtained following its constitutive expression. Plant Mol Biol 2004 0.98
53 Towards dissecting nutrient metabolism in plants: a systems biology case study on sulphur metabolism. J Exp Bot 2004 0.98
54 Integration of genome-scale modeling and transcript profiling reveals metabolic pathways underlying light and temperature acclimation in Arabidopsis. Plant Cell 2013 0.97
55 Inhibition of aconitase by nitric oxide leads to induction of the alternative oxidase and to a shift of metabolism towards biosynthesis of amino acids. J Exp Bot 2012 0.96
56 Cell wall invertase expression at the apical meristem alters floral, architectural, and reproductive traits in Arabidopsis thaliana. Plant J 2004 0.96
57 Expression of a yeast-derived invertase in companion cells results in long-distance transport of a trisaccharide in an apoplastic loader and influences sucrose transport. Planta 2003 0.96
58 Improved heterosis prediction by combining information on DNA- and metabolic markers. PLoS One 2009 0.95
59 Engineering central metabolism in crop species: learning the system. Metab Eng 2003 0.94
60 Analysis of the compartmentalized metabolome - a validation of the non-aqueous fractionation technique. Front Plant Sci 2011 0.93
61 Constitutive expression of the beta-ketothiolase gene in transgenic plants. A major obstacle for obtaining polyhydroxybutyrate-producing plants. Plant Physiol 2002 0.91
62 Linking gene expression and membrane lipid composition of Arabidopsis. Plant Cell 2014 0.91
63 Discrimination of wine attributes by metabolome analysis. Anal Chem 2010 0.91
64 Corn hybrids display lower metabolite variability and complex metabolite inheritance patterns. Plant J 2011 0.91
65 Stability of metabolic correlations under changing environmental conditions in Escherichia coli--a systems approach. PLoS One 2009 0.91
66 Network visualization and network analysis. EXS 2007 0.90
67 A tyrosine aminotransferase involved in tocopherol synthesis in Arabidopsis. Plant J 2012 0.90
68 Analysis of ven3 and ven6 reticulate mutants reveals the importance of arginine biosynthesis in Arabidopsis leaf development. Plant J 2010 0.89
69 Modulation of fructokinase activity of potato (Solanum tuberosum) results in substantial shifts in tuber metabolism. Plant Cell Physiol 2005 0.88
70 Identification of enzymatic and regulatory genes of plant metabolism through QTL analysis in Arabidopsis. J Plant Physiol 2011 0.87
71 Potato hexokinase 2 complements transgenic Arabidopsis plants deficient in hexokinase 1 but does not play a key role in tuber carbohydrate metabolism. Plant Mol Biol 2002 0.87
72 Chimeric RNA/DNA oligonucleotide-based site-specific modification of the tobacco acetolactate syntase gene. Plant Physiol 2003 0.87
73 Expression of a yeast acetyl CoA hydrolase in the mitochondrion of tobacco plants inhibits growth and restricts photosynthesis. Plant Mol Biol 2004 0.87
74 In plants the alc gene expression system responds more rapidly following induction with acetaldehyde than with ethanol. FEBS Lett 2003 0.86
75 Prediction of hybrid biomass in Arabidopsis thaliana by selected parental SNP and metabolic markers. Theor Appl Genet 2009 0.86
76 Analysis of subcellular metabolite levels of potato tubers (Solanum tuberosum) displaying alterations in cellular or extracellular sucrose metabolism. Metabolomics 2008 0.85
77 Enhancing vacuolar sucrose cleavage within the developing potato tuber has only minor effects on metabolism. Plant Cell Physiol 2005 0.84
78 Subcellular pyrophosphate metabolism in developing tubers of potato (Solanum tuberosum). Plant Mol Biol 2006 0.83
79 Metabolic analysis of adaptation to short-term changes in culture conditions of the marine diatom Thalassiosira pseudonana. PLoS One 2013 0.83
80 Expression of an Escherichia coli phosphoglucomutase in potato (Solanum tuberosum L.) results in minor changes in tuber metabolism and a considerable delay in tuber sprouting. Planta 2005 0.82
81 Involvement of the hexose transporter gene LeHT1 and of sugars in resistance of tomato to tomato yellow leaf curl virus. Mol Plant 2013 0.81
82 Liquid chromatography high-resolution mass spectrometry for fatty acid profiling. Plant J 2015 0.81
83 The maize leaf lipidome shows multilevel genetic control and high predictive value for agronomic traits. Sci Rep 2013 0.81
84 Functional Redundancy and Divergence within the Arabidopsis RETICULATA-RELATED Gene Family. Plant Physiol 2013 0.80
85 Unraveling retrograde signaling pathways: finding candidate signaling molecules via metabolomics and systems biology driven approaches. Front Plant Sci 2012 0.80
86 Expression of a bacterial xylose isomerase in potato tubers results in an altered hexose composition and a consequent induction of metabolism. Plant Cell Physiol 2003 0.80
87 Integrating profiling data: using linear correlation to reveal coregulation of transcript and metabolites. Methods Mol Biol 2007 0.79
88 The LysM receptor-like kinase LysM RLK1 is required to activate defense and abiotic-stress responses induced by overexpression of fungal chitinases in Arabidopsis plants. Mol Plant 2012 0.79
89 Discovery of new modules in metabolic biology using ChemoMetabolomics. Plant Physiol 2012 0.78
90 Comparison of metabolite profiles in U87 glioma cells and mesenchymal stem cells. Biosystems 2011 0.78
91 VMP1-deficient Chlamydomonas exhibits severely aberrant cell morphology and disrupted cytokinesis. BMC Plant Biol 2014 0.78
92 Metabolomic linkage reveals functional interaction between glucose-dependent insulinotropic polypeptide and ghrelin in humans. Am J Physiol Endocrinol Metab 2011 0.77
93 Analysis of the interface between primary and secondary metabolism in catharanthus roseus cell cultures using (13)C-stable isotope feeding and coupled mass spectrometry. Mol Plant 2012 0.76
94 Tuber-specific cytosolic expression of a bacterial phosphoglucomutase in potato (Solanum tuberosum L.) dramatically alters carbon partitioning. Plant Cell Physiol 2005 0.76
95 Consequences of induced brassinosteroid deficiency in Arabidopsis leaves. BMC Plant Biol 2014 0.76
96 Corrigendum: Gas chromatography mass spectrometry-based metabolite profiling in plants. Nat Protoc 2015 0.76
97 A yeast-based model system for cloning secreted and membrane proteins. An Acad Bras Cienc 2003 0.75