Published in Nat Rev Genet on January 01, 2007
Efficient control of population structure in model organism association mapping. Genetics (2008) 12.32
High-resolution genetic mapping using the Mouse Diversity outbred population. Genetics (2012) 3.28
Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels. Aging Cell (2009) 3.16
A quantitative trait locus (LSq-1) on mouse chromosome 7 is linked to the absence of tissue loss after surgical hindlimb ischemia. Circulation (2008) 2.77
Copper-free click chemistry in living animals. Proc Natl Acad Sci U S A (2010) 2.76
Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice. Aging Cell (2008) 2.65
Host genetic background strongly influences the response to influenza a virus infections. PLoS One (2009) 2.28
One medicine, one pathology, and the one health concept. J Am Vet Med Assoc (2009) 2.28
A comprehensive collection of experimentally validated primers for Polymerase Chain Reaction quantitation of murine transcript abundance. BMC Genomics (2008) 2.07
Genome-wide association studies and the problem of relatedness among advanced intercross lines and other highly recombinant populations. Genetics (2010) 2.06
Genomic copy number and expression variation within the C57BL/6J inbred mouse strain. Genome Res (2007) 1.71
Linkage disequilibrium in wild mice. PLoS Genet (2007) 1.70
Genome-wide assessments reveal extremely high levels of polymorphism of two active families of mouse endogenous retroviral elements. PLoS Genet (2008) 1.69
Mouse consomic strains: exploiting genetic divergence between Mus m. musculus and Mus m. domesticus subspecies. Genome Res (2008) 1.66
Exploring the elephant: histopathology in high-throughput phenotyping of mutant mice. Dis Model Mech (2011) 1.62
The mouse as a model for understanding chronic diseases of aging: the histopathologic basis of aging in inbred mice. Pathobiol Aging Age Relat Dis (2011) 1.56
Nucleotide variation in wild and inbred mice. Genetics (2007) 1.55
Practical applications of the bioinformatics toolbox for narrowing quantitative trait loci. Genetics (2008) 1.49
Liraglutide Compromises Pancreatic β Cell Function in a Humanized Mouse Model. Cell Metab (2016) 1.44
Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits. Mamm Genome (2012) 1.43
Quantitative proteomics by metabolic labeling of model organisms. Mol Cell Proteomics (2009) 1.42
Primary follicular dystrophy with scarring dermatitis in C57BL/6 mouse substrains resembles central centrifugal cicatricial alopecia in humans. Vet Pathol (2010) 1.32
Altered upper airway and soft tissue structures in the New Zealand Obese mouse. Am J Respir Crit Care Med (2008) 1.30
Phenotype ontologies for mouse and man: bridging the semantic gap. Dis Model Mech (2010) 1.28
Genetics of SLE: evidence from mouse models. Nat Rev Rheumatol (2010) 1.27
Gramene QTL database: development, content and applications. Database (Oxford) (2009) 1.25
Mice as a mammalian model for research on the genetics of aging. ILAR J (2011) 1.20
Genetically engineered mouse models in cancer research. Adv Cancer Res (2010) 1.18
Mouse genetic and phenotypic resources for human genetics. Hum Mutat (2012) 1.18
Functional and morphological effects of laser-induced ocular hypertension in retinas of adult albino Swiss mice. Mol Vis (2009) 1.15
Large-scale in silico mapping of complex quantitative traits in inbred mice. PLoS One (2007) 1.08
Genetic loci modulating amyloid-beta levels in a mouse model of Alzheimer's disease. Neurobiol Aging (2007) 1.07
Robust activation of the human but not mouse telomerase gene during the induction of pluripotency. FASEB J (2010) 1.07
Applying gene expression, proteomics and single-nucleotide polymorphism analysis for complex trait gene identification. Genetics (2008) 1.07
Complex genetics of obesity in mouse models. Annu Rev Nutr (2008) 1.06
Mouse gestation length is genetically determined. PLoS One (2010) 1.06
The expanding role of mouse genetics for understanding human biology and disease. Dis Model Mech (2008) 1.05
Fine-mapping alleles for body weight in LG/J × SM/J F₂ and F(34) advanced intercross lines. Mamm Genome (2011) 1.05
A survey of airway responsiveness in 36 inbred mouse strains facilitates gene mapping studies and identification of quantitative trait loci. Mol Genet Genomics (2010) 1.05
Biology of obesity: lessons from animal models of obesity. J Biomed Biotechnol (2011) 1.05
Searching for genes underlying behavior: lessons from circadian rhythms. Science (2008) 1.04
Interaction of enteric bacterial pathogens with murine embryonic stem cells. Infect Immun (2008) 1.03
Genetically engineered pig models for human diseases. Annu Rev Anim Biosci (2013) 1.01
Genome-wide association studies and genetic risk assessment of liver diseases. Nat Rev Gastroenterol Hepatol (2010) 0.99
Systems genetics, bioinformatics and eQTL mapping. Genetica (2010) 0.99
The mouse QTL map helps interpret human genome-wide association studies for HDL cholesterol. J Lipid Res (2011) 0.98
Quantitative trait locus analysis of carotid atherosclerosis in an intercross between C57BL/6 and C3H apolipoprotein E-deficient mice. Stroke (2007) 0.95
Genetic control of severe egg-induced immunopathology and IL-17 production in murine schistosomiasis. J Immunol (2009) 0.94
A method to identify and validate mitochondrial modulators using mammalian cells and the worm C. elegans. Sci Rep (2014) 0.93
Telomeres, atherosclerosis, and human longevity: a causal hypothesis. Epidemiology (2015) 0.93
Genome-wide association for fear conditioning in an advanced intercross mouse line. Behav Genet (2012) 0.93
Sequence variation at multiple loci influences red cell hemoglobin concentration. Blood (2010) 0.92
Online tools for understanding rat physiology. Brief Bioinform (2010) 0.92
Approaches to Investigating Complex Genetic Traits in a Large-Scale Inbred Mouse Aging Study. Vet Pathol (2016) 0.91
Mouse-specific tandem IgY7-SuperMix immunoaffinity separations for improved LC-MS/MS coverage of the plasma proteome. J Proteome Res (2009) 0.91
WNT1-inducible signaling pathway protein 1 contributes to ventilator-induced lung injury. Am J Respir Cell Mol Biol (2012) 0.91
Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene. PLoS One (2013) 0.91
Genome-wide association for methamphetamine sensitivity in an advanced intercross mouse line. Genes Brain Behav (2011) 0.91
Using expression genetics to study the neurobiology of ethanol and alcoholism. Int Rev Neurobiol (2010) 0.90
A novel strategy for genetic dissection of complex traits: the population of specific chromosome substitution strains from laboratory and wild mice. Mamm Genome (2010) 0.90
Immune status, strain background, and anatomic site of inoculation affect mouse papillomavirus (MmuPV1) induction of exophytic papillomas or endophytic trichoblastomas. PLoS One (2014) 0.89
Forward genetic dissection of innate response to infection in inbred mouse strains: selected success stories. Clin Exp Immunol (2010) 0.89
Quantitative lymphatic vessel trait analysis suggests Vcam1 as candidate modifier gene of inflammatory bowel disease. Genes Immun (2010) 0.89
The value of animal models in predicting genetic susceptibility to complex diseases such as rheumatoid arthritis. Arthritis Res Ther (2009) 0.88
Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice. BMC Genomics (2016) 0.88
Host genetic background influences the response to the opportunistic Pseudomonas aeruginosa infection altering cell-mediated immunity and bacterial replication. PLoS One (2014) 0.87
CFTR regulates early pathogenesis of chronic obstructive lung disease in βENaC-overexpressing mice. PLoS One (2012) 0.87
Contrasting genetic architectures in different mouse reference populations used for studying complex traits. Genome Res (2015) 0.86
Different responsiveness to a high-fat/cholesterol diet in two inbred mice and underlying genetic factors: a whole genome microarray analysis. Nutr Metab (Lond) (2009) 0.86
In silico QTL mapping of basal liver iron levels in inbred mouse strains. Physiol Genomics (2010) 0.86
Towards the integration of mouse databases - definition and implementation of solutions to two use-cases in mouse functional genomics. BMC Res Notes (2010) 0.85
Cardiovascular consequences of sleep apnea. Lung (2011) 0.85
New approaches to the representation and analysis of phenotype knowledge in human diseases and their animal models. Brief Funct Genomics (2011) 0.85
Inbred and outbred mice have equivalent variability in a cockroach allergen-induced model of asthma. Comp Med (2010) 0.84
Generation of highly homogeneous strains of zebrafish through full sib-pair mating. G3 (Bethesda) (2011) 0.84
The mouse age phenome knowledgebase and disease-specific inter-species age mapping. PLoS One (2013) 0.84
Atherosclerosis susceptibility Loci identified in an extremely atherosclerosis-resistant mouse strain. J Am Heart Assoc (2013) 0.84
Cofilin-1: a modulator of anxiety in mice. PLoS Genet (2012) 0.84
Evidence that Gsta4 modifies susceptibility to skin tumor development in mice and humans. J Natl Cancer Inst (2010) 0.84
Vesico-ureteric reflux: using mouse models to understand a common congenital urinary tract defect. Pediatr Nephrol (2011) 0.84
Application of Mouse Models to Research in Hearing and Balance. J Assoc Res Otolaryngol (2016) 0.83
A quantitative trait locus on chromosome 4 affects cycling of hematopoietic stem and progenitor cells through regulation of TGF-beta 2 responsiveness. J Immunol (2008) 0.83
Quantitative trait loci for exercise training responses in FVB/NJ and C57BL/6J mice. Physiol Genomics (2009) 0.82
Mouse genetic approaches applied to the normal tissue radiation response. Front Oncol (2012) 0.82
A high-fat diet supplemented with fish oil improves metabolic features associated with type 2 diabetes. Nutrition (2013) 0.81
A novel mouse model of in-stent restenosis. Atherosclerosis (2009) 0.81
SYSGENET: a meeting report from a new European network for systems genetics. Mamm Genome (2010) 0.80
Host genetic diversity influences the severity of Pseudomonas aeruginosa pneumonia in the Collaborative Cross mice. BMC Genet (2015) 0.80
The Founder Strains of the Collaborative Cross Express a Complex Combination of Advantageous and Deleterious Traits for Male Reproduction. G3 (Bethesda) (2015) 0.80
QTLs for murine red blood cell parameters in LG/J and SM/J F(2) and advanced intercross lines. Mamm Genome (2012) 0.80
Individual Monitoring of Immune Response in Atlantic Salmon Salmo salar following Experimental Infection with Infectious Salmon Anaemia Virus (ISAV). PLoS One (2015) 0.79
Dissection of complex adult traits in a mouse synthetic population. Genome Res (2012) 0.79
The case for genetic monitoring of mice and rats used in biomedical research. Mamm Genome (2013) 0.79
Wild mice as bountiful resources of novel genetic variants for quantitative traits. Curr Genomics (2013) 0.78
Genetic interactions between chromosomes 11 and 18 contribute to airway hyperresponsiveness in mice. PLoS One (2012) 0.78
Mouse resources for craniofacial research. Genesis (2011) 0.78
A quantitative trait locus on chr.4 regulates thymic involution. J Gerontol A Biol Sci Med Sci (2010) 0.77
Genetic regulation of bone strength: a review of animal model studies. Bonekey Rep (2015) 0.77
From mouse genetics to systems biology. Mamm Genome (2007) 0.77
R/qtl: QTL mapping in experimental crosses. Bioinformatics (2003) 22.38
Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol (2007) 10.49
MGD: the Mouse Genome Database. Nucleic Acids Res (2003) 10.14
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nat Biotechnol (2007) 9.36
The Mouse Genome Database (MGD): updates and enhancements. Nucleic Acids Res (2006) 8.87
The Mouse Genome Database (MGD): from genes to mice--a community resource for mouse biology. Nucleic Acids Res (2005) 8.19
Statistical tests for differential expression in cDNA microarray experiments. Genome Biol (2003) 7.65
The Mouse Genome Database (MGD): the model organism database for the laboratory mouse. Nucleic Acids Res (2002) 7.47
Variation in gene expression within and among natural populations. Nat Genet (2002) 7.19
The Mouse Genome Database (MGD): comprehensive resource for genetics and genomics of the laboratory mouse. Nucleic Acids Res (2011) 5.60
Improved statistical tests for differential gene expression by shrinking variance components estimates. Biostatistics (2005) 5.57
Lineage-specific biology revealed by a finished genome assembly of the mouse. PLoS Biol (2009) 5.45
On the subspecific origin of the laboratory mouse. Nat Genet (2007) 4.68
The Mouse Genome Database (MGD): premier model organism resource for mammalian genomics and genetics. Nucleic Acids Res (2010) 4.58
The mouse genome database (MGD): new features facilitating a model system. Nucleic Acids Res (2006) 4.52
The Mouse Tumor Biology Database: a public resource for cancer genetics and pathology of the mouse. Cancer Res (2002) 4.31
The nature and identification of quantitative trait loci: a community's view. Nat Rev Genet (2003) 3.96
The Protein Ontology: a structured representation of protein forms and complexes. Nucleic Acids Res (2010) 3.74
Subspecific origin and haplotype diversity in the laboratory mouse. Nat Genet (2011) 3.64
A customized and versatile high-density genotyping array for the mouse. Nat Methods (2009) 3.53
The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics. Mamm Genome (2008) 3.52
The Mouse Genome Database genotypes::phenotypes. Nucleic Acids Res (2008) 3.48
High-resolution genetic mapping using the Mouse Diversity outbred population. Genetics (2012) 3.28
Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Res (2011) 3.25
The IKMC web portal: a central point of entry to data and resources from the International Knockout Mouse Consortium. Nucleic Acids Res (2010) 3.23
Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels. Aging Cell (2009) 3.16
Bayesian model selection for genome-wide epistatic quantitative trait loci analysis. Genetics (2005) 3.10
MouseCyc: a curated biochemical pathways database for the laboratory mouse. Genome Biol (2009) 3.06
A new standard genetic map for the laboratory mouse. Genetics (2009) 2.78
Evidence of a large-scale functional organization of mammalian chromosomes. PLoS Genet (2005) 2.73
Multiple trait measurements in 43 inbred mouse strains capture the phenotypic diversity characteristic of human populations. J Appl Physiol (1985) (2007) 2.70
Connecting sequence and biology in the laboratory mouse. Genome Res (2003) 2.69
The Mouse Genome Database: integration of and access to knowledge about the laboratory mouse. Nucleic Acids Res (2013) 2.68
The mammalian gene function resource: the International Knockout Mouse Consortium. Mamm Genome (2012) 2.65
Folding and organization of a contiguous chromosome region according to the gene distribution pattern in primary genomic sequence. J Cell Biol (2006) 2.63
An imputed genotype resource for the laboratory mouse. Mamm Genome (2008) 2.54
Transcript annotation in FANTOM3: mouse gene catalog based on physical cDNAs. PLoS Genet (2006) 2.48
Structural model analysis of multiple quantitative traits. PLoS Genet (2006) 2.45
Mouse Phenome Database (MPD). Nucleic Acids Res (2006) 2.43
Crossover interference in the mouse. Genetics (2002) 2.40
A genomewide functional network for the laboratory mouse. PLoS Comput Biol (2008) 2.25
Transformations for cDNA microarray data. Stat Appl Genet Mol Biol (2003) 2.23
Beyond the data deluge: data integration and bio-ontologies. J Biomed Inform (2006) 2.20
The Mouse Tumor Biology database. Nat Rev Cancer (2008) 2.15
Effects of atherogenic diet on hepatic gene expression across mouse strains. Physiol Genomics (2009) 2.00
Sex- and lineage-specific inheritance of depression-like behavior in the rat. Mamm Genome (2004) 1.99
Towards BioDBcore: a community-defined information specification for biological databases. Nucleic Acids Res (2010) 1.97
Macromolecule biosynthesis: a key function of sleep. Physiol Genomics (2007) 1.93
The Diversity Outbred mouse population. Mamm Genome (2012) 1.85
Discrimination of non-protein-coding transcripts from protein-coding mRNA. RNA Biol (2006) 1.82
Integrating computationally assembled mouse transcript sequences with the Mouse Genome Informatics (MGI) database. Genome Biol (2003) 1.82
A collaborative database of inbred mouse strain characteristics. Bioinformatics (2004) 1.79
Quantitative trait locus analysis for obesity reveals multiple networks of interacting loci. Mamm Genome (2006) 1.74
Genetic analysis in the Collaborative Cross breeding population. Genome Res (2011) 1.74
Using advanced intercross lines for high-resolution mapping of HDL cholesterol quantitative trait loci. Genome Res (2003) 1.66
Mouse consomic strains: exploiting genetic divergence between Mus m. musculus and Mus m. domesticus subspecies. Genome Res (2008) 1.66
The X chromosome in quantitative trait locus mapping. Genetics (2006) 1.65
Mouse phenome database. Nucleic Acids Res (2008) 1.59
Combining data from multiple inbred line crosses improves the power and resolution of quantitative trait loci mapping. Genetics (2005) 1.58
Quantitative trait loci analysis for plasma HDL-cholesterol concentrations and atherosclerosis susceptibility between inbred mouse strains C57BL/6J and 129S1/SvImJ. Arterioscler Thromb Vasc Biol (2003) 1.58
Statistical design and the analysis of gene expression microarray data. Genet Res (2007) 1.56
Tissue-specific functional networks for prioritizing phenotype and disease genes. PLoS Comput Biol (2012) 1.54
Mapping quantitative trait loci for vertebral trabecular bone volume fraction and microarchitecture in mice. J Bone Miner Res (2003) 1.52
PPARgamma2 nuclear receptor controls multiple regulatory pathways of osteoblast differentiation from marrow mesenchymal stem cells. J Cell Biochem (2009) 1.51
A torrid zone on mouse chromosome 1 containing a cluster of recombinational hotspots. Genetics (2004) 1.51
PPARG by dietary fat interaction influences bone mass in mice and humans. J Bone Miner Res (2008) 1.50
Ten years of the collaborative cross. G3 (Bethesda) (2012) 1.50
Antibodies that label paraffin-embedded mouse tissues: a collaborative endeavor. Toxicol Pathol (2004) 1.43
Modeling host genetic regulation of influenza pathogenesis in the collaborative cross. PLoS Pathog (2013) 1.43
Imputation of single-nucleotide polymorphisms in inbred mice using local phylogeny. Genetics (2012) 1.42
Differences in health status affect susceptibility and mapping of genetic loci for atherosclerosis (fatty streak) in inbred mice. Arterioscler Thromb Vasc Biol (2012) 1.40
Discovery of novel variants in genotyping arrays improves genotype retention and reduces ascertainment bias. BMC Genomics (2012) 1.39
Genetic analysis of hematological parameters in incipient lines of the collaborative cross. G3 (Bethesda) (2012) 1.35
Genetics of colitis susceptibility in IL-10-deficient mice: backcross versus F2 results contrasted by principal component analysis. Genomics (2002) 1.35
Selective phenotyping for increased efficiency in genetic mapping studies. Genetics (2004) 1.34
Genetic analysis of blood pressure in 8 mouse intercross populations. Hypertension (2009) 1.33
Protein Ontology: a controlled structured network of protein entities. Nucleic Acids Res (2013) 1.33
FXR and ABCG5/ABCG8 as determinants of cholesterol gallstone formation from quantitative trait locus mapping in mice. Gastroenterology (2003) 1.29
The collaborative cross: a recombinant inbred mouse population for the systems genetic era. ILAR J (2011) 1.28
Quantitative trait loci that determine plasma lipids and obesity in C57BL/6J and 129S1/SvImJ inbred mice. J Lipid Res (2004) 1.28
Genetic analysis of albuminuria in a cross between C57BL/6J and DBA/2J mice. Am J Physiol Renal Physiol (2007) 1.27
Effects of FXR in foam-cell formation and atherosclerosis development. Biochim Biophys Acta (2006) 1.26
Quantitative trait locus study design from an information perspective. Genetics (2005) 1.26
Strain-specific effects of rosiglitazone on bone mass, body composition, and serum insulin-like growth factor-I. Endocrinology (2008) 1.26
Towards BioDBcore: a community-defined information specification for biological databases. Database (Oxford) (2011) 1.24
Multiple mechanisms limit the duration of wakefulness in Drosophila brain. Physiol Genomics (2006) 1.23
What are microarrays teaching us about sleep? Trends Mol Med (2009) 1.22
Ten years of the Collaborative Cross. Genetics (2012) 1.22
A general Bayesian approach to analyzing diallel crosses of inbred strains. Genetics (2012) 1.20
Architecture of energy balance traits in emerging lines of the Collaborative Cross. Am J Physiol Endocrinol Metab (2011) 1.20
Femur mechanical properties in the F2 progeny of an NZB/B1NJ x RF/J cross are regulated predominantly by genetic loci that regulate bone geometry. J Bone Miner Res (2006) 1.19
QTL analysis of self-selected macronutrient diet intake: fat, carbohydrate, and total kilocalories. Physiol Genomics (2002) 1.18
Mouse BMD quantitative trait loci show improved concordance with human genome-wide association loci when recalculated on a new, common mouse genetic map. J Bone Miner Res (2010) 1.17
Quantitative trait loci that determine BMD in C57BL/6J and 129S1/SvImJ inbred mice. J Bone Miner Res (2005) 1.17
Genome-wide association mapping of quantitative traits in outbred mice. G3 (Bethesda) (2012) 1.17
Four additional mouse crosses improve the lipid QTL landscape and identify Lipg as a QTL gene. J Lipid Res (2009) 1.16