Jonathan S Stamler

Author PubWeight™ 201.46‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Protein S-nitrosylation: purview and parameters. Nat Rev Mol Cell Biol 2005 10.65
2 Relationship of blood transfusion and clinical outcomes in patients with acute coronary syndromes. JAMA 2004 5.11
3 Regulated protein denitrosylation by cytosolic and mitochondrial thioredoxins. Science 2008 4.51
4 Nitric oxide in the human respiratory cycle. Nat Med 2002 4.50
5 Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock. Cell 2004 3.98
6 Protein S-nitrosylation in health and disease: a current perspective. Trends Mol Med 2009 3.75
7 Redox-based regulation of signal transduction: principles, pitfalls, and promises. Free Radic Biol Med 2008 3.38
8 Chemical physiology of blood flow regulation by red blood cells: the role of nitric oxide and S-nitrosohemoglobin. Annu Rev Physiol 2005 3.19
9 Protection from experimental asthma by an endogenous bronchodilator. Science 2005 3.17
10 S-nitrosylation in cardiovascular signaling. Circ Res 2010 3.02
11 S-nitrosylation in health and disease. Trends Mol Med 2003 2.85
12 Assessment and application of the biotin switch technique for examining protein S-nitrosylation under conditions of pharmacologically induced oxidative stress. J Biol Chem 2007 2.85
13 OxyR: a molecular code for redox-related signaling. Cell 2002 2.83
14 S-nitrosohemoglobin deficiency: a mechanism for loss of physiological activity in banked blood. Proc Natl Acad Sci U S A 2007 2.77
15 Proteomic analysis of S-nitrosylation and denitrosylation by resin-assisted capture. Nat Biotechnol 2009 2.69
16 Identification of the enzymatic mechanism of nitroglycerin bioactivation. Proc Natl Acad Sci U S A 2002 2.65
17 Regulation of beta-adrenergic receptor signaling by S-nitrosylation of G-protein-coupled receptor kinase 2. Cell 2007 2.65
18 Protein denitrosylation: enzymatic mechanisms and cellular functions. Nat Rev Mol Cell Biol 2009 2.42
19 A novel protective effect of erythropoietin in the infarcted heart. J Clin Invest 2003 2.32
20 Central role of mitochondrial aldehyde dehydrogenase and reactive oxygen species in nitroglycerin tolerance and cross-tolerance. J Clin Invest 2004 2.22
21 An S-nitrosothiol (SNO) synthase function of hemoglobin that utilizes nitrite as a substrate. Proc Natl Acad Sci U S A 2006 2.21
22 An essential role for mitochondrial aldehyde dehydrogenase in nitroglycerin bioactivation. Proc Natl Acad Sci U S A 2005 2.18
23 Basal and stimulated protein S-nitrosylation in multiple cell types and tissues. J Biol Chem 2002 2.14
24 Endogenous S-nitrosothiols protect against myocardial injury. Proc Natl Acad Sci U S A 2009 2.13
25 Nitric oxide regulates endocytosis by S-nitrosylation of dynamin. Proc Natl Acad Sci U S A 2006 1.99
26 Detection of protein S-nitrosylation with the biotin-switch technique. Free Radic Biol Med 2008 1.95
27 NO/redox disequilibrium in the failing heart and cardiovascular system. J Clin Invest 2005 1.94
28 Inhaled ethyl nitrite gas for persistent pulmonary hypertension of the newborn. Lancet 2002 1.93
29 S-nitrosothiol signaling in respiratory biology. Am J Respir Crit Care Med 2006 1.84
30 Routes to S-nitroso-hemoglobin formation with heme redox and preferential reactivity in the beta subunits. Proc Natl Acad Sci U S A 2003 1.81
31 S-nitrosylating agents: a novel class of compounds that increase cystic fibrosis transmembrane conductance regulator expression and maturation in epithelial cells. Mol Pharmacol 2006 1.79
32 Site-specific analysis of protein S-acylation by resin-assisted capture. J Lipid Res 2010 1.77
33 Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2. Cell 2011 1.77
34 S-nitrosothiols in the blood: roles, amounts, and methods of analysis. Circ Res 2004 1.76
35 Enzymes that counteract nitrosative stress promote fungal virulence. Curr Biol 2003 1.75
36 Impaired vasodilation by red blood cells in sickle cell disease. Proc Natl Acad Sci U S A 2005 1.74
37 Concern Protection from lipopolysaccharide-induced lung injury by augmentation of airway S-nitrosothiols. Am J Respir Crit Care Med 2009 1.74
38 Regulation by S-nitrosylation of protein post-translational modification. J Biol Chem 2011 1.68
39 A nitric oxide processing defect of red blood cells created by hypoxia: deficiency of S-nitrosohemoglobin in pulmonary hypertension. Proc Natl Acad Sci U S A 2005 1.67
40 Oxygen-regulated beta(2)-adrenergic receptor hydroxylation by EGLN3 and ubiquitylation by pVHL. Sci Signal 2009 1.66
41 S-nitrosylation of beta-arrestin regulates beta-adrenergic receptor trafficking. Mol Cell 2008 1.63
42 NOS2 regulation of NF-kappaB by S-nitrosylation of p65. J Biol Chem 2007 1.62
43 Maintenance of nitric oxide and redox homeostasis by the salmonella flavohemoglobin hmp. J Biol Chem 2006 1.58
44 New insights into protein S-nitrosylation. Mitochondria as a model system. J Biol Chem 2004 1.57
45 The SNO-proteome: causation and classifications. Curr Opin Chem Biol 2010 1.56
46 Acute effects of aerosolized S-nitrosoglutathione in cystic fibrosis. Am J Respir Crit Care Med 2002 1.51
47 Bioactivation of nitroglycerin by the mitochondrial aldehyde dehydrogenase. Trends Cardiovasc Med 2006 1.47
48 Concerted regulation of skeletal muscle contractility by oxygen tension and endogenous nitric oxide. Proc Natl Acad Sci U S A 2003 1.44
49 Hypoxic vasodilation by red blood cells: evidence for an s-nitrosothiol-based signal. Circ Res 2008 1.42
50 A central role for S-nitrosylation in apoptosis. Nat Cell Biol 2005 1.36
51 Endogenous protein S-Nitrosylation in E. coli: regulation by OxyR. Science 2012 1.34
52 Assessments of the chemistry and vasodilatory activity of nitrite with hemoglobin under physiologically relevant conditions. J Inorg Biochem 2005 1.30
53 Hemoglobin, nitric oxide and molecular mechanisms of hypoxic vasodilation. Trends Mol Med 2009 1.29
54 A protein microarray-based analysis of S-nitrosylation. Proc Natl Acad Sci U S A 2009 1.29
55 S-nitrosylation: physiological regulation of NF-kappaB. Proc Natl Acad Sci U S A 2004 1.28
56 A genetic analysis of nitrosative stress. Biochemistry 2009 1.25
57 Enzymatic mechanisms regulating protein S-nitrosylation: implications in health and disease. J Mol Med (Berl) 2012 1.23
58 Identification of S-nitrosylated targets of thioredoxin using a quantitative proteomic approach. Biochemistry 2010 1.23
59 Inhaled ethyl nitrite prevents hyperoxia-impaired postnatal alveolar development in newborn rats. Am J Respir Crit Care Med 2007 1.23
60 S-nitrosoglutathione reductase: an important regulator in human asthma. Am J Respir Crit Care Med 2009 1.22
61 Cardioprotective effects of erythropoietin in the reperfused ischemic heart: a potential role for cardiac fibroblasts. J Biol Chem 2004 1.20
62 Screening for nitric oxide-dependent protein-protein interactions. Science 2003 1.20
63 Assessment of nitric oxide signals by triiodide chemiluminescence. Proc Natl Acad Sci U S A 2007 1.20
64 Structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487. J Biol Chem 2007 1.19
65 Nitric oxide, NOC-12, and S-nitrosoglutathione modulate the skeletal muscle calcium release channel/ryanodine receptor by different mechanisms. An allosteric function for O2 in S-nitrosylation of the channel. J Biol Chem 2002 1.19
66 Host S-nitrosylation inhibits clostridial small molecule-activated glucosylating toxins. Nat Med 2011 1.19
67 Oxygen-coupled redox regulation of the skeletal muscle ryanodine receptor-Ca2+ release channel by NADPH oxidase 4. Proc Natl Acad Sci U S A 2011 1.19
68 Dynamic denitrosylation via S-nitrosoglutathione reductase regulates cardiovascular function. Proc Natl Acad Sci U S A 2012 1.18
69 Regulation of the cardiac muscle ryanodine receptor by O(2) tension and S-nitrosoglutathione. Biochemistry 2008 1.17
70 S-nitrosylation: integrator of cardiovascular performance and oxygen delivery. J Clin Invest 2013 1.12
71 S-Nitrosylation of cardiac ion channels. J Cardiovasc Pharmacol 2009 1.12
72 Fiber type-specific nitric oxide protects oxidative myofibers against cachectic stimuli. PLoS One 2008 1.10
73 Regulation of ion channel structure and function by reactive oxygen-nitrogen species. Am J Physiol Lung Cell Mol Physiol 2003 1.10
74 Nitrosative stress-induced apoptosis through inhibition of NF-kappa B. J Biol Chem 2002 1.09
75 Thioredoxin-interacting protein (Txnip) is a feedback regulator of S-nitrosylation. J Biol Chem 2009 1.09
76 Myeloid Krüppel-like factor 4 deficiency augments atherogenesis in ApoE-/- mice--brief report. Arterioscler Thromb Vasc Biol 2012 1.09
77 Role of mitochondrial aldehyde dehydrogenase in nitroglycerin-induced vasodilation of coronary and systemic vessels: an intact canine model. Circulation 2004 1.08
78 Aberrant S-nitrosylation mediates calcium-triggered ventricular arrhythmia in the intact heart. Proc Natl Acad Sci U S A 2012 1.02
79 Nitrosative stress in the ER: a new role for S-nitrosylation in neurodegenerative diseases. ACS Chem Biol 2006 1.01
80 Oxygen regulation of tumor perfusion by S-nitrosohemoglobin reveals a pressor activity of nitric oxide. Circ Res 2005 1.00
81 GSNO reductase and beta2-adrenergic receptor gene-gene interaction: bronchodilator responsiveness to albuterol. Pharmacogenet Genomics 2010 1.00
82 Nascent nitrosylases. Nat Cell Biol 2010 0.96
83 Erythropoietin, anemia, and orthostatic hypotension: the evidence mounts. Clin Auton Res 2002 0.95
84 S-nitrosoglutathione inhibits alpha1-adrenergic receptor-mediated vasoconstriction and ligand binding in pulmonary artery. Am J Physiol Lung Cell Mol Physiol 2005 0.95
85 Avicinylation (thioesterification): a protein modification that can regulate the response to oxidative and nitrosative stress. Proc Natl Acad Sci U S A 2005 0.95
86 Blood traffic control. Nature 2004 0.95
87 A method to attenuate pneumoperitoneum-induced reductions in splanchnic blood flow. Ann Surg 2005 0.95
88 Convergence of G protein-coupled receptor and S-nitrosylation signaling determines the outcome to cardiac ischemic injury. Sci Signal 2013 0.94
89 Role of circulating S-nitrosothiols in control of blood pressure. Hypertension 2004 0.92
90 S-nitrosylation therapy to improve oxygen delivery of banked blood. Proc Natl Acad Sci U S A 2013 0.92
91 Interactions of NO with hemoglobin: from microbes to man. Methods Enzymol 2008 0.92
92 SNO-hemoglobin and hypoxic vasodilation. Nat Med 2008 0.92
93 Nitroxyl disulfides, novel intermediates in transnitrosation reactions. J Am Chem Soc 2003 0.92
94 Oxygen-coupled redox regulation of the skeletal muscle ryanodine receptor/Ca2+ release channel (RyR1): sites and nature of oxidative modification. J Biol Chem 2013 0.92
95 Kruppel-like factor 4 is critical for transcriptional control of cardiac mitochondrial homeostasis. J Clin Invest 2015 0.91
96 A classification scheme for redox-based modifications of proteins. Am J Respir Cell Mol Biol 2007 0.91
97 The transfusion problem: role of aberrant S-nitrosylation. Transfusion 2011 0.91
98 Nitrite-methemoglobin inadequate for hypoxic vasodilation. Nat Chem Biol 2009 0.91
99 Inclusion of a nitric oxide congener in the insufflation gas repletes S-nitrosohemoglobin and stabilizes physiologic status during prolonged carbon dioxide pneumoperitoneum. Clin Transl Sci 2009 0.90
100 Nitric oxide transport in blood: a third gas in the respiratory cycle. Compr Physiol 2011 0.89
101 Co-regulation of constitutive nitric oxide synthases and NADPH oxidase by the small GTPase Rac. FEBS Lett 2008 0.89
102 Insights into BAY 60-2770 activation and S-nitrosylation-dependent desensitization of soluble guanylyl cyclase via crystal structures of homologous nostoc H-NOX domain complexes. Biochemistry 2013 0.88
103 Nitric oxide in RBCs. Transfusion 2002 0.88
104 Off-target thiol alkylation by the NADPH oxidase inhibitor 3-benzyl-7-(2-benzoxazolyl)thio-1,2,3-triazolo[4,5-d]pyrimidine (VAS2870). Free Radic Biol Med 2012 0.87
105 Hemoglobin S-nitrosylation plays an essential role in cardioprotection. J Clin Invest 2016 0.87
106 S-Nitrosylation at the interface of autophagy and disease. Mol Cell 2011 0.86
107 The pharmacology of aminoadamantane nitrates. Curr Alzheimer Res 2006 0.85
108 Pulmonary vasoconstriction by serotonin is inhibited by S-nitrosoglutathione. Am J Physiol Lung Cell Mol Physiol 2002 0.84
109 Role of nitric oxide in vasodilation in upstream muscle during intermittent pneumatic compression. J Appl Physiol (1985) 2002 0.84
110 Pharmacologically augmented S-nitrosylated hemoglobin improves recovery from murine subarachnoid hemorrhage. Stroke 2010 0.84
111 Myocyte specific overexpression of myoglobin impairs angiogenesis after hind-limb ischemia. Arterioscler Thromb Vasc Biol 2008 0.84
112 Hemoglobin and nitric oxide. N Engl J Med 2003 0.83
113 Assays for S-nitrosothiols and S-nitrosylated proteins and mechanistic insights into cardioprotection. Circulation 2009 0.81
114 Nitroglycerin-mediated S-nitrosylation of proteins: a field comes full cycle. Circ Res 2008 0.81
115 Regulation of the skeletal muscle ryanodine receptor/Ca2+-release channel RyR1 by S-palmitoylation. J Biol Chem 2014 0.81
116 Translation of academic discovery into societal benefit: proposal for a balanced approach--part 1. Am J Med 2003 0.80
117 S-nitrosylation and PEGylation of hemoglobin: toward a blood substitute that recapitulates blood. J Mol Cell Cardiol 2007 0.80
118 Inhibition of iNOS with 1400W improves contractile function and alters nos gene and protein expression in reperfused skeletal muscle. Microsurgery 2004 0.80
119 Clostridial toxins: sensing a target in a hostile gut environment. Gut Microbes 2012 0.80
120 A novel inhaled organic nitrate that affects pulmonary vascular tone in a piglet model of hypoxia-induced pulmonary hypertension. Pediatr Res 2005 0.79
121 Reduction of cardiomyocyte S-nitrosylation by S-nitrosoglutathione reductase protects against sepsis-induced myocardial depression. Am J Physiol Heart Circ Physiol 2013 0.79
122 Reperfusion injury is reduced in skeletal muscle by inhibition of inducible nitric oxide synthase. J Appl Physiol (1985) 2002 0.79
123 S-nitrosylation TRiPs a calcium switch. Nat Chem Biol 2006 0.78
124 Dual targeting of the thioredoxin and glutathione systems in cancer and HIV. J Clin Invest 2016 0.78
125 Is the flavohemoglobin a nitric oxide dioxygenase? Free Radic Biol Med 2012 0.78
126 Identifying single S-nitrosothiol sites with cardioprotection. Circ Res 2013 0.78
127 S-nitrosohemoglobin is distinguished from other nitrosovasodilators by unique oxygen-dependent responses that support an allosteric mechanism of action. Blood 2003 0.78
128 Repletion of S-nitrosohemoglobin improves organ function and physiological status in swine after brain death. Ann Surg 2013 0.77
129 EPR spectroscopy of nitrite complexes of methemoglobin. Inorg Chem 2010 0.77
130 Efficacy of ethyl nitrite in reversing surgical vasospasm. J Reconstr Microsurg 2007 0.77
131 Maternal insufflation during the second trimester equivalent produces hypercapnia, acidosis, and prolonged hypoxia in fetal sheep. Anesthesiology 2004 0.76
132 Endocrine nitric oxide bioactivity and hypoxic vasodilation by inhaled nitric oxide. Circ Res 2012 0.76
133 An unusual case of peripartum pulmonary oedema. BMJ Case Rep 2013 0.75
134 Editorial for "Methods for analysis of nitric oxide signalling by S-nitrosylation". Methods 2013 0.75