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Author PubWeight™ 172.06‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Coupling of local folding to site-specific binding of proteins to DNA. Science 1994 9.49
2 Thermodynamic analysis of ion effects on the binding and conformational equilibria of proteins and nucleic acids: the roles of ion association or release, screening, and ion effects on water activity. Q Rev Biophys 1978 9.44
3 Ion effects on ligand-nucleic acid interactions. J Mol Biol 1976 5.52
4 Characterization of the cytoplasm of Escherichia coli K-12 as a function of external osmolarity. Implications for protein-DNA interactions in vivo. J Mol Biol 1991 3.73
5 Polypeptides containing highly conserved regions of transcription initiation factor sigma 70 exhibit specificity of binding to promoter DNA. Cell 1992 3.27
6 Use of liquid hydrocarbon and amide transfer data to estimate contributions to thermodynamic functions of protein folding from the removal of nonpolar and polar surface from water. Biochemistry 1992 3.26
7 RNA polymerase-promoter interactions: the comings and goings of RNA polymerase. J Bacteriol 1998 3.16
8 Contribution to the thermodynamics of protein folding from the reduction in water-accessible nonpolar surface area. Biochemistry 1991 2.83
9 Factor independent activation of rrnB P1. An "extended" promoter with an upstream element that dramatically increases promoter strength. J Mol Biol 1994 2.73
10 Variability of the intracellular ionic environment of Escherichia coli. Differences between in vitro and in vivo effects of ion concentrations on protein-DNA interactions and gene expression. J Biol Chem 1987 2.67
11 Upstream operators enhance repression of the lac promoter. Science 1986 2.58
12 Electrostatic effects on polynucleotide transitions. II. Behavior of titrated systems. Biopolymers 1967 2.55
13 Enthalpy and heat capacity changes for formation of an oligomeric DNA duplex: interpretation in terms of coupled processes of formation and association of single-stranded helices. Biochemistry 1999 2.54
14 Salt-nucleic acid interactions. Annu Rev Phys Chem 1995 2.50
15 Replacement of potassium chloride by potassium glutamate dramatically enhances protein-DNA interactions in vitro. Biochemistry 1987 2.45
16 Origins of the osmoprotective properties of betaine and proline in Escherichia coli K-12. J Bacteriol 1992 2.34
17 Vapor pressure osmometry studies of osmolyte-protein interactions: implications for the action of osmoprotectants in vivo and for the interpretation of "osmotic stress" experiments in vitro. Biochemistry 2000 2.24
18 Interpretation of monovalent and divalent cation effects on the lac repressor-operator interaction. Biochemistry 1977 2.23
19 Role of the hydrophobic effect in stability of site-specific protein-DNA complexes. J Mol Biol 1989 2.20
20 Analysis of equilibrium and kinetic measurements to determine thermodynamic origins of stability and specificity and mechanism of formation of site-specific complexes between proteins and helical DNA. Methods Enzymol 1991 2.18
21 Inhibition of transcription initiation by lac repressor. J Mol Biol 1995 2.13
22 Monte Carlo description of oligoelectrolyte properties of DNA oligomers: range of the end effect and the approach of molecular and thermodynamic properties to the polyelectrolyte limits. Proc Natl Acad Sci U S A 1989 2.11
23 Thermodynamic origins of specificity in the lac repressor-operator interaction. Adaptability in the recognition of mutant operator sites. J Mol Biol 1985 2.00
24 Equilibrium dialysis studies of polyamine binding to DNA. Biopolymers 1982 1.97
25 Nonspecific interaction of lac repressor with DNA: an association reaction driven by counterion release. Biochemistry 1977 1.95
26 Temperature dependence of the rate constants of the Escherichia coli RNA polymerase-lambda PR promoter interaction. Assignment of the kinetic steps corresponding to protein conformational change and DNA opening. J Mol Biol 1985 1.93
27 Hydrophobic effect in protein folding and other noncovalent processes involving proteins. Proc Natl Acad Sci U S A 1989 1.92
28 Kinetics and mechanism of the interaction of Escherichia coli RNA polymerase with the lambda PR promoter. J Mol Biol 1984 1.84
29 Physical properties of DNA in vivo as probed by the length dependence of the lac operator looping process. Biochemistry 1988 1.83
30 Thermodynamic analysis of interactions between denaturants and protein surface exposed on unfolding: interpretation of urea and guanidinium chloride m-values and their correlation with changes in accessible surface area (ASA) using preferential interaction coefficients and the local-bulk domain model. Proteins 2000 1.79
31 Pentalysine-deoxyribonucleic acid interactions: a model for the general effects of ion concentrations on the interactions of proteins with nucleic acids. Biochemistry 1980 1.78
32 Biophysical characterization of changes in amounts and activity of Escherichia coli cell and compartment water and turgor pressure in response to osmotic stress. Biophys J 2000 1.73
33 Relative binding affinities of monovalent cations for double-stranded DNA. Proc Natl Acad Sci U S A 1980 1.73
34 Ion distributions around DNA and other cylindrical polyions: theoretical descriptions and physical implications. Annu Rev Biophys Biophys Chem 1990 1.73
35 Sodium-23 NMR studies of cation-DNA interactions. Biophys Chem 1978 1.73
36 Double helical DNA: conformations, physical properties, and interactions with ligands. Annu Rev Biochem 1981 1.73
37 Thermodynamics of interactions of urea and guanidinium salts with protein surface: relationship between solute effects on protein processes and changes in water-accessible surface area. Protein Sci 2001 1.69
38 HO. and DNase I probing of E sigma 70 RNA polymerase--lambda PR promoter open complexes: Mg2+ binding and its structural consequences at the transcription start site. Biochemistry 1995 1.68
39 Nonspecific interactions of Escherichia coli RNA polymerase with native and denatured DNA: differences in the binding behavior of core and holoenzyme. Biochemistry 1978 1.67
40 In vivo thermodynamic analysis of repression with and without looping in lac constructs. Estimates of free and local lac repressor concentrations and of physical properties of a region of supercoiled plasmid DNA in vivo. J Mol Biol 1993 1.67
41 DNA footprints of the two kinetically significant intermediates in formation of an RNA polymerase-promoter open complex: evidence that interactions with start site and downstream DNA induce sequential conformational changes in polymerase and DNA. J Mol Biol 1998 1.64
42 Importance of oligoelectrolyte end effects for the thermodynamics of conformational transitions of nucleic acid oligomers: a grand canonical Monte Carlo analysis. Biopolymers 1991 1.64
43 Thermodynamics of the interactions of lac repressor with variants of the symmetric lac operator: effects of converting a consensus site to a non-specific site. J Mol Biol 1997 1.63
44 Specific and non-specific interactions of integration host factor with DNA: thermodynamic evidence for disruption of multiple IHF surface salt-bridges coupled to DNA binding. J Mol Biol 2001 1.60
45 Two open complexes and a requirement for Mg2+ to open the lambda PR transcription start site. Science 1993 1.51
46 Conformational transitions of duplex and triplex nucleic acid helices: thermodynamic analysis of effects of salt concentration on stability using preferential interaction coefficients. Biophys J 1994 1.50
47 Stable DNA loops in vivo and in vitro: roles in gene regulation at a distance and in biophysical characterization of DNA. Prog Nucleic Acid Res Mol Biol 1990 1.39
48 Na+ effects on transition of DNA and polynucleotides of variable linear charge density. Biopolymers 1976 1.36
49 The relationship between the poisson-boltzmann model and the condensation hypothesis: an analysis based on the low salt form of the Donnan coefficient. Biophys Chem 1980 1.36
50 Rapid response to osmotic upshift by osmoregulated genes in Escherichia coli and Salmonella typhimurium. J Bacteriol 1988 1.34
51 Thermodynamic stoichiometries of participation of water, cations and anions in specific and non-specific binding of lac repressor to DNA. Possible thermodynamic origins of the "glutamate effect" on protein-DNA interactions. J Mol Biol 1992 1.33
52 Regulation of the kinetics of the interaction of Escherichia coli RNA polymerase with the lambda PR promoter by salt concentration. Biochemistry 1985 1.29
53 Analytic binding isotherms describing competitive interactions of a protein ligand with specific and nonspecific sites on the same DNA oligomer. Biophys J 2001 1.28
54 In an Escherichia coli coupled transcription-translation system, expression of the osmoregulated gene proU is stimulated at elevated potassium concentrations and by an extract from cells grown at high osmolality. J Biol Chem 1989 1.28
55 Intermediates in the formation of the open complex by RNA polymerase holoenzyme containing the sigma factor sigma 32 at the groE promoter. J Mol Biol 1989 1.28
56 Importance of coulombic end effects on cation accumulation near oligoelectrolyte B-DNA: a demonstration using 23Na NMR. Biophys J 1995 1.25
57 The importance of coulombic end effects: experimental characterization of the effects of oligonucleotide flanking charges on the strength and salt dependence of oligocation (L8+) binding to single-stranded DNA oligomers. Biophys J 1999 1.25
58 Variables affecting the selectivity and efficiency of retention of DNA fragments by E. coli RNA polymerase in the nitrocellulose-filter-binding assay. Gene 1981 1.21
59 Grand canonical Monte Carlo molecular and thermodynamic predictions of ion effects on binding of an oligocation (L8+) to the center of DNA oligomers. Biophys J 1995 1.21
60 Ions as regulators of protein-nucleic acid interactions in vitro and in vivo. Adv Biophys 1985 1.17
61 Mg NMR in DNA solutions: Dominance of site binding effects. Proc Natl Acad Sci U S A 1980 1.15
62 Electrostatic effects on polynucleotide transitions. I. Behavior at neutral pH. Biopolymers 1967 1.15
63 Nitrocellulose filter binding studies of the interactions of Escherichia coli RNA polymerase holoenzyme with deoxyribonucleic acid restriction fragments: evidence for multiple classes of nonpromoter interactions, some of which display promoter-like properties. Biochemistry 1982 1.14
64 Cooperative and anticooperative effects in binding of the first and second plasmid Osym operators to a LacI tetramer: evidence for contributions of non-operator DNA binding by wrapping and looping. J Mol Biol 1996 1.12
65 Direct evidence for the preferential binding of Escherichia coli RNA polymerase holoenzyme to the ends of deoxyribonucleic acid restriction fragments. Biochemistry 1983 1.11
66 Accumulation of 3-(N-morpholino)propanesulfonate by osmotically stressed Escherichia coli K-12. J Bacteriol 1989 1.11
67 Characterization of rodlike RNA fragments. Biopolymers 1975 1.10
68 Wrapping of flanking non-operator DNA in lac repressor-operator complexes: implications for DNA looping. J Mol Biol 1999 1.09
69 23Na NMR relaxation study of the effects of conformation and base composition on the interactions of counterions with double-helical DNA. Biochemistry 1984 1.09
70 Competitive interactions of Co(NH3)6(3+) and Na+ with helical B-DNA probed by 59Co and 23Na NMR. Biochemistry 1987 1.07
71 Thermodynamic characterization of interactions of native bovine serum albumin with highly excluded (glycine betaine) and moderately accumulated (urea) solutes by a novel application of vapor pressure osmometry. Biochemistry 1996 1.07
72 General method of analysis of kinetic equations for multistep reversible mechanisms in the single-exponential regime: application to kinetics of open complex formation between Esigma70 RNA polymerase and lambdaP(R) promoter DNA. Biophys J 1999 1.06
73 Measurement of binding constants for protein-DNA interactions by DNA-cellulose chromatography. Biochemistry 1977 1.03
74 Compensating effects of opposing changes in putrescine (2+) and K+ concentrations on lac repressor-lac operator binding: in vitro thermodynamic analysis and in vivo relevance. J Mol Biol 1996 1.03
75 Large electrostatic differences in the binding thermodynamics of a cationic peptide to oligomeric and polymeric DNA. Proc Natl Acad Sci U S A 1996 1.02
76 Roles of Mg2+ in the mechanism of formation and dissociation of open complexes between Escherichia coli RNA polymerase and the lambda PR promoter: kinetic evidence for a second open complex requiring Mg2+. Biochemistry 1992 1.02
77 Relative affinities of divalent polyamines and of their N-methylated analogues for helical DNA determined by 23Na NMR. Biochemistry 1991 1.02
78 23Na-NMR investigations of counterion exchange reactions of helical DNA. Biopolymers 1986 1.01
79 Ion effects on the aggregation and DNA-binding reactions of Escherichia coli RNA polymerase. Cold Spring Harb Symp Quant Biol 1983 1.00
80 Binding of Escherichia coli ribonucleic acid polymerase holoenzyme to a bacteriophage T7 promoter-containing fragment: selectivity exists over a wide range of solution conditions. Biochemistry 1980 1.00
81 Binding of Escherichia coli ribonucleic acid polymerase holoenzyme to a bacteriophage T7 promoter-containing fragment: evaluation of promoter binding constants as a function of solution conditions. Biochemistry 1980 1.00
82 Analyses of thermodynamic data for concentrated hemoglobin solutions using scaled particle theory: implications for a simple two-state model of water in thermodynamic analyses of crowding in vitro and in vivo. Biophys J 1995 1.00
83 Interaction of an N-methylated polyamine analogue, hexamethonium(2+), with NaDNA: quantitative 14N and 23Na NMR relaxation rate studies of the cation-exchange process. Biochemistry 1988 0.99
84 Kinetics of the helix-coil transition in DNA. Biopolymers 1972 0.99
85 Analysis of ion concentration effects of the kinetics of protein-nucleic acid interactions. Application to lac repressor-operator interactions. Biophys Chem 1978 0.99
86 Binding of cationic (+4) alanine- and glycine-containing oligopeptides to double-stranded DNA: thermodynamic analysis of effects of coulombic interactions and alpha-helix induction. Biochemistry 1997 0.97
87 Quantifying accumulation or exclusion of H(+), HO(-), and Hofmeister salt ions near interfaces. Chem Phys Lett 2008 0.95
88 Aggregation equilibria of Escherichia coli RNA polymerase: evidence for anion-linked conformational transitions in the protomers of core and holoenzyme. Biochemistry 1982 0.95
89 E. coli promoter spacer regions contain nonrandom sequences which correlate to spacer length. Nucleic Acids Res 1990 0.94
90 Counterion exchange reactions on DNA: Monte Carlo and Poisson-Boltzmann analysis. Biopolymers 1988 0.93
91 The strand-separation transition of T2 bacteriophage DNA. Biopolymers 1974 0.92
92 Quantitative analysis of multiple-hit footprinting studies to characterize DNA conformational changes in protein-DNA complexes: application to DNA opening by Esigma70 RNA polymerase. J Mol Biol 1998 0.91
93 Preferential interactions between small solutes and the protein backbone: a computational analysis. Biochemistry 2010 0.87
94 The strand-separation transition of T7 DNA. Biopolymers 1974 0.86
95 Use of difference boundary sedimentation velocity to investigate nonspecific protein-nucleic acid interactions. Biochemistry 1980 0.85
96 Thermodynamic investigation of hirudin binding to the slow and fast forms of thrombin: evidence for folding transitions in the inhibitor and protease coupled to binding. J Mol Biol 1995 0.85
97 A method for horizontal polyacrylamide slab gel electrophoresis. Biotechniques 1989 0.82
98 K(+)-ribosome interactions determine the large enhancements of 39K NMR transverse relaxation rates in the cytoplasm of Escherichia coli K-12. Biochemistry 1995 0.81
99 Association kinetics of site-specific protein-DNA interactions: roles of nonspecific DNA sites and of the molecular location of the specific site. Biopolymers 1989 0.78
100 Do sigma factors need help with a meltdown? Cell 2006 0.76
101 Intermediates in the strand-separation transition of T7 DNA. Biopolymers 1976 0.75
102 Preparative-scale purification of DNA restriction fragments by continuous-flow gel electrophoresis. Biotechniques 1995 0.75
103 Cooperativity in biochemistry: cooperativity theory in biochemistry. Science 1985 0.75
104 Molecular interactions. Science 1978 0.75
105 Kinetics of nonspecific binding reactions of proteins with DNA flexible coils: site-based and molecule-based association reactions. Biopolymers 1986 0.75