Published in Biochemistry on April 30, 1991
Denaturant m values and heat capacity changes: relation to changes in accessible surface areas of protein unfolding. Protein Sci (1995) 9.23
How Hofmeister ion interactions affect protein stability. Biophys J (1996) 3.48
Bound water molecules and conformational stabilization help mediate an antigen-antibody association. Proc Natl Acad Sci U S A (1994) 2.18
X-ray crystal structures of the oxidized and reduced forms of the rubredoxin from the marine hyperthermophilic archaebacterium Pyrococcus furiosus. Protein Sci (1992) 2.11
Binding of the estrogen receptor to DNA. The role of waters. Biophys J (1997) 2.02
The design and characterization of two proteins with 88% sequence identity but different structure and function. Proc Natl Acad Sci U S A (2007) 1.91
Lessons in stability from thermophilic proteins. Protein Sci (2006) 1.88
Differential geometry based solvation model I: Eulerian formulation. J Comput Phys (2010) 1.74
Thermodynamics of interactions of urea and guanidinium salts with protein surface: relationship between solute effects on protein processes and changes in water-accessible surface area. Protein Sci (2001) 1.69
Thermodynamics reveal that helix four in the NLS of NF-kappaB p65 anchors IkappaBalpha, forming a very stable complex. J Mol Biol (2006) 1.59
Thermodynamic origin of hofmeister ion effects. J Phys Chem B (2008) 1.50
Direct evidence for modified solvent structure within the hydration shell of a hydrophobic amino acid. Proc Natl Acad Sci U S A (1996) 1.38
The paradoxical thermodynamic basis for the interaction of ethylene glycol, glycine, and sarcosine chains with bovine carbonic anhydrase II: an unexpected manifestation of enthalpy/entropy compensation. J Am Chem Soc (2006) 1.31
Use of urea and glycine betaine to quantify coupled folding and probe the burial of DNA phosphates in lac repressor-lac operator binding. Biochemistry (2005) 1.31
Why Hofmeister effects of many salts favor protein folding but not DNA helix formation. Proc Natl Acad Sci U S A (2010) 1.30
Interactions of the osmolyte glycine betaine with molecular surfaces in water: thermodynamics, structural interpretation, and prediction of m-values. Biochemistry (2009) 1.29
A two-component system regulates the expression of an ABC transporter for xylo-oligosaccharides in Geobacillus stearothermophilus. Appl Environ Microbiol (2006) 1.28
Structural basis for p300 Taz2-p53 TAD1 binding and modulation by phosphorylation. Structure (2009) 1.28
Differential geometry based solvation model II: Lagrangian formulation. J Math Biol (2011) 1.27
Molecular mechanisms of system control of NF-kappaB signaling by IkappaBalpha. Biochemistry (2010) 1.25
BPPred: a Web-based computational tool for predicting biophysical parameters of proteins. Protein Sci (2006) 1.14
Analysis of the factors that stabilize a designed two-stranded antiparallel beta-sheet. Protein Sci (2002) 1.14
Water-mediated protein-DNA interactions: the relationship of thermodynamics to structural detail. Protein Sci (1996) 1.13
Mapping glycoside hydrolase substrate subsites by isothermal titration calorimetry. Proc Natl Acad Sci U S A (2004) 1.07
Potential of mean force calculations of the stacking-unstacking process in single-stranded deoxyribodinucleoside monophosphates. Biophys J (1995) 1.07
Two distinct motifs within the p53 transactivation domain bind to the Taz2 domain of p300 and are differentially affected by phosphorylation. Biochemistry (2009) 1.05
High affinity antigen recognition of the dual specific variants of herceptin is entropy-driven in spite of structural plasticity. PLoS One (2011) 1.03
Thermodynamic and structural analysis of microtubule assembly: the role of GTP hydrolysis. Biophys J (1997) 1.02
Temperature effects in hydrophobic interaction chromatography. Proc Natl Acad Sci U S A (1996) 1.02
Interaction of the DNA-binding domain of Drosophila heat shock factor with its cognate DNA site: a thermodynamic analysis using analytical ultracentrifugation. Protein Sci (1994) 1.02
Toward the physical basis of thermophilic proteins: linking of enriched polar interactions and reduced heat capacity of unfolding. Biophys J (2002) 1.01
On the entropy of protein folding. Protein Sci (1996) 1.01
Heat capacity changes and hydrophobic interactions in the binding of FK506 and rapamycin to the FK506 binding protein. Proc Natl Acad Sci U S A (1992) 1.00
Contributions of folding cores to the thermostabilities of two ribonucleases H. Protein Sci (2002) 0.99
Probing the protein-folding mechanism using denaturant and temperature effects on rate constants. Proc Natl Acad Sci U S A (2013) 0.98
Transcriptional repression in the Notch pathway: thermodynamic characterization of CSL-MINT (Msx2-interacting nuclear target protein) complexes. J Biol Chem (2011) 0.98
Thermodynamic and structural insights into CSL-DNA complexes. Protein Sci (2010) 0.97
Variational approach for nonpolar solvation analysis. J Chem Phys (2012) 0.97
Unfolding studies on soybean agglutinin and concanavalin a tetramers: a comparative account. Biophys J (2004) 0.96
Folding of a pressure-denatured model protein. Proc Natl Acad Sci U S A (1999) 0.95
Sidedness of interfacial arginine residues and anti-atherogenicity of apolipoprotein A-I mimetic peptides. J Lipid Res (2012) 0.93
Relation between the convergence temperatures Th* and Ts* in protein unfolding. Proc Natl Acad Sci U S A (1992) 0.92
Binding-linked protonation of a DNA minor-groove agent. Biophys J (2005) 0.91
Role of hydration water in protein unfolding. Biophys J (1999) 0.90
Hydrophobic side-chain size is a determinant of the three-dimensional structure of the p53 oligomerization domain. EMBO J (1997) 0.90
Interactions defining the specificity between fungal xylanases and the xylanase-inhibiting protein XIP-I from wheat. Biochem J (2002) 0.89
Substrate-dependent switching of the allosteric binding mechanism of a dimeric enzyme. Nat Chem Biol (2014) 0.89
Correspondence between anomalous m- and DeltaCp-values in protein folding. Protein Sci (2004) 0.89
Complex relationship between ligand binding and dimerization in the epidermal growth factor receptor. Cell Rep (2014) 0.88
Thermal and conformational stability of Ssh10b protein from archaeon Sulfolobus shibattae. Biochem J (2004) 0.88
Probing protein conformation with a minimal photochemical reagent. Protein Sci (2002) 0.87
Enthalpic and entropic contributions mediate the role of disulfide bonds on the conformational stability of interleukin-4. Protein Sci (2006) 0.87
Thermodynamics of unfolding of an integral membrane protein in mixed micelles. Protein Sci (2006) 0.86
Thermodynamics of specific and nonspecific DNA binding by two DNA-binding domains conjugated to fluorescent probes. Biophys J (2001) 0.85
Properties of hydrophobic free energy found by gas-liquid transfer. Proc Natl Acad Sci U S A (2013) 0.85
Comparison of binding energies of SrcSH2-phosphotyrosyl peptides with structure-based prediction using surface area based empirical parameterization. Protein Sci (2000) 0.84
Effect of hydrostatic pressure on unfolding of alpha-lactalbumin: volumetric equivalence of the molten globule and unfolded state. Protein Sci (1999) 0.84
Using surface tension data to predict differences in surface and bulk concentrations of nonelectrolytes in water. J Phys Chem C Nanomater Interfaces (2009) 0.84
Basis of Protein Stabilization by K Glutamate: Unfavorable Interactions with Carbon, Oxygen Groups. Biophys J (2016) 0.84
Nonspecific DNA binding and bending by HUαβ: interfaces of the three binding modes characterized by salt-dependent thermodynamics. J Mol Biol (2011) 0.83
Frozen in Time: The History of Proteins. Mol Biol Evol (2017) 0.82
An intramolecular interaction involving the N terminus of a streptococcal adhesin affects its conformation and adhesive function. J Biol Chem (2013) 0.82
Dynamics of ribonuclease A and ribonuclease S: computational and experimental studies. Protein Sci (1996) 0.82
Influence of Glu-376 --> Gln mutation on enthalpy and heat capacity changes for the binding of slightly altered ligands to medium chain acyl-CoA dehydrogenase. Protein Sci (2001) 0.81
Structural basis for difference in heat capacity increments for Ca(2+) binding to two alpha-lactalbumins. Biophys J (2002) 0.81
Contribution of asparagine residues to the stabilization of a proteinaceous antigen-antibody complex, HyHEL-10-hen egg white lysozyme. J Biol Chem (2009) 0.81
Chemical denaturation as a tool in the formulation optimization of biologics. Drug Discov Today (2013) 0.80
A survey of peptides with effective therapeutic potential in Alzheimer's disease rodent models or in human clinical studies. Mini Rev Med Chem (2012) 0.79
Alpha-helical topology prediction and generation of distance restraints in membrane proteins. Biophys J (2008) 0.79
Gas-liquid transfer data used to analyze hydrophobic hydration and find the nature of the Kauzmann-Tanford hydrophobic factor. Proc Natl Acad Sci U S A (2012) 0.79
Stability curve prediction of homologous proteins using temperature-dependent statistical potentials. PLoS Comput Biol (2014) 0.78
Thermodynamic and structural basis for relaxation of specificity in protein-DNA recognition. J Mol Biol (2013) 0.78
Influence of the H-site residue 108 on human glutathione transferase P1-1 ligand binding: structure-thermodynamic relationships and thermal stability. Protein Sci (2009) 0.78
Sequence specific and high affinity recognition of 5'-ACGCGT-3' by rationally designed pyrrole-imidazole H-pin polyamides: thermodynamic and structural studies. Bioorg Med Chem (2008) 0.77
A multidisciplinary approach to probing enthalpy-entropy compensation and the interfacial mobility model. J Am Chem Soc (2011) 0.77
Biophysical characterization of anticoagulant hemextin AB complex from the venom of snake Hemachatus haemachatus. Biophys J (2007) 0.77
Hydrophobic interactions are the driving force for the binding of peptide mimotopes and Staphylococcal protein A to recombinant human IgG1. Eur Biophys J (2007) 0.76
Consequences of fuzziness in the NFκB/IκBα interaction. Adv Exp Med Biol (2012) 0.76
The Hydrophobic Effect in Solute Partitioning and Interfacial Tension. Sci Rep (2016) 0.75
An enthalpic basis of additivity in biphenyl hydroxamic acid ligands for stromelysin-1. Bioorg Med Chem Lett (2012) 0.75
In silico Evaluation of Crosslinking Effects on Denaturant m(eq) values and ΔCp upon Protein Unfolding. Avicenna J Med Biotechnol (2012) 0.75
Ligand-induced protein mobility in complexes of carbonic anhydrase II and benzenesulfonamides with oligoglycine chains. PLoS One (2013) 0.75
Parameter optimization in differential geometry based solvation models. J Chem Phys (2015) 0.75
Coupling of local folding to site-specific binding of proteins to DNA. Science (1994) 9.49
Thermodynamic analysis of ion effects on the binding and conformational equilibria of proteins and nucleic acids: the roles of ion association or release, screening, and ion effects on water activity. Q Rev Biophys (1978) 9.44
Ion effects on ligand-nucleic acid interactions. J Mol Biol (1976) 5.52
Characterization of the cytoplasm of Escherichia coli K-12 as a function of external osmolarity. Implications for protein-DNA interactions in vivo. J Mol Biol (1991) 3.73
Polypeptides containing highly conserved regions of transcription initiation factor sigma 70 exhibit specificity of binding to promoter DNA. Cell (1992) 3.27
Use of liquid hydrocarbon and amide transfer data to estimate contributions to thermodynamic functions of protein folding from the removal of nonpolar and polar surface from water. Biochemistry (1992) 3.26
RNA polymerase-promoter interactions: the comings and goings of RNA polymerase. J Bacteriol (1998) 3.16
Factor independent activation of rrnB P1. An "extended" promoter with an upstream element that dramatically increases promoter strength. J Mol Biol (1994) 2.73
Variability of the intracellular ionic environment of Escherichia coli. Differences between in vitro and in vivo effects of ion concentrations on protein-DNA interactions and gene expression. J Biol Chem (1987) 2.67
Upstream operators enhance repression of the lac promoter. Science (1986) 2.58
Electrostatic effects on polynucleotide transitions. II. Behavior of titrated systems. Biopolymers (1967) 2.55
Enthalpy and heat capacity changes for formation of an oligomeric DNA duplex: interpretation in terms of coupled processes of formation and association of single-stranded helices. Biochemistry (1999) 2.54
Salt-nucleic acid interactions. Annu Rev Phys Chem (1995) 2.50
Replacement of potassium chloride by potassium glutamate dramatically enhances protein-DNA interactions in vitro. Biochemistry (1987) 2.45
Origins of the osmoprotective properties of betaine and proline in Escherichia coli K-12. J Bacteriol (1992) 2.34
Vapor pressure osmometry studies of osmolyte-protein interactions: implications for the action of osmoprotectants in vivo and for the interpretation of "osmotic stress" experiments in vitro. Biochemistry (2000) 2.24
Interpretation of monovalent and divalent cation effects on the lac repressor-operator interaction. Biochemistry (1977) 2.23
Role of the hydrophobic effect in stability of site-specific protein-DNA complexes. J Mol Biol (1989) 2.20
Analysis of equilibrium and kinetic measurements to determine thermodynamic origins of stability and specificity and mechanism of formation of site-specific complexes between proteins and helical DNA. Methods Enzymol (1991) 2.18
Inhibition of transcription initiation by lac repressor. J Mol Biol (1995) 2.13
Monte Carlo description of oligoelectrolyte properties of DNA oligomers: range of the end effect and the approach of molecular and thermodynamic properties to the polyelectrolyte limits. Proc Natl Acad Sci U S A (1989) 2.11
Thermodynamic origins of specificity in the lac repressor-operator interaction. Adaptability in the recognition of mutant operator sites. J Mol Biol (1985) 2.00
Equilibrium dialysis studies of polyamine binding to DNA. Biopolymers (1982) 1.97
Nonspecific interaction of lac repressor with DNA: an association reaction driven by counterion release. Biochemistry (1977) 1.95
Hydrophobic effect in protein folding and other noncovalent processes involving proteins. Proc Natl Acad Sci U S A (1989) 1.92
Kinetics and mechanism of the interaction of Escherichia coli RNA polymerase with the lambda PR promoter. J Mol Biol (1984) 1.84
Physical properties of DNA in vivo as probed by the length dependence of the lac operator looping process. Biochemistry (1988) 1.83
Pentalysine-deoxyribonucleic acid interactions: a model for the general effects of ion concentrations on the interactions of proteins with nucleic acids. Biochemistry (1980) 1.78
Biophysical characterization of changes in amounts and activity of Escherichia coli cell and compartment water and turgor pressure in response to osmotic stress. Biophys J (2000) 1.73
Relative binding affinities of monovalent cations for double-stranded DNA. Proc Natl Acad Sci U S A (1980) 1.73
Ion distributions around DNA and other cylindrical polyions: theoretical descriptions and physical implications. Annu Rev Biophys Biophys Chem (1990) 1.73
Sodium-23 NMR studies of cation-DNA interactions. Biophys Chem (1978) 1.73
Double helical DNA: conformations, physical properties, and interactions with ligands. Annu Rev Biochem (1981) 1.73
Thermodynamics of interactions of urea and guanidinium salts with protein surface: relationship between solute effects on protein processes and changes in water-accessible surface area. Protein Sci (2001) 1.69
HO. and DNase I probing of E sigma 70 RNA polymerase--lambda PR promoter open complexes: Mg2+ binding and its structural consequences at the transcription start site. Biochemistry (1995) 1.68
Nonspecific interactions of Escherichia coli RNA polymerase with native and denatured DNA: differences in the binding behavior of core and holoenzyme. Biochemistry (1978) 1.67
Importance of oligoelectrolyte end effects for the thermodynamics of conformational transitions of nucleic acid oligomers: a grand canonical Monte Carlo analysis. Biopolymers (1991) 1.64
Thermodynamics of the interactions of lac repressor with variants of the symmetric lac operator: effects of converting a consensus site to a non-specific site. J Mol Biol (1997) 1.63
Specific and non-specific interactions of integration host factor with DNA: thermodynamic evidence for disruption of multiple IHF surface salt-bridges coupled to DNA binding. J Mol Biol (2001) 1.60
Two open complexes and a requirement for Mg2+ to open the lambda PR transcription start site. Science (1993) 1.51
Conformational transitions of duplex and triplex nucleic acid helices: thermodynamic analysis of effects of salt concentration on stability using preferential interaction coefficients. Biophys J (1994) 1.50
Stable DNA loops in vivo and in vitro: roles in gene regulation at a distance and in biophysical characterization of DNA. Prog Nucleic Acid Res Mol Biol (1990) 1.39
Na+ effects on transition of DNA and polynucleotides of variable linear charge density. Biopolymers (1976) 1.36
The relationship between the poisson-boltzmann model and the condensation hypothesis: an analysis based on the low salt form of the Donnan coefficient. Biophys Chem (1980) 1.36
Rapid response to osmotic upshift by osmoregulated genes in Escherichia coli and Salmonella typhimurium. J Bacteriol (1988) 1.34
Regulation of the kinetics of the interaction of Escherichia coli RNA polymerase with the lambda PR promoter by salt concentration. Biochemistry (1985) 1.29
Analytic binding isotherms describing competitive interactions of a protein ligand with specific and nonspecific sites on the same DNA oligomer. Biophys J (2001) 1.28
In an Escherichia coli coupled transcription-translation system, expression of the osmoregulated gene proU is stimulated at elevated potassium concentrations and by an extract from cells grown at high osmolality. J Biol Chem (1989) 1.28
Intermediates in the formation of the open complex by RNA polymerase holoenzyme containing the sigma factor sigma 32 at the groE promoter. J Mol Biol (1989) 1.28
Importance of coulombic end effects on cation accumulation near oligoelectrolyte B-DNA: a demonstration using 23Na NMR. Biophys J (1995) 1.25
Grand canonical Monte Carlo molecular and thermodynamic predictions of ion effects on binding of an oligocation (L8+) to the center of DNA oligomers. Biophys J (1995) 1.21
Variables affecting the selectivity and efficiency of retention of DNA fragments by E. coli RNA polymerase in the nitrocellulose-filter-binding assay. Gene (1981) 1.21
Ions as regulators of protein-nucleic acid interactions in vitro and in vivo. Adv Biophys (1985) 1.17
Mg NMR in DNA solutions: Dominance of site binding effects. Proc Natl Acad Sci U S A (1980) 1.15
Electrostatic effects on polynucleotide transitions. I. Behavior at neutral pH. Biopolymers (1967) 1.15
Cooperative and anticooperative effects in binding of the first and second plasmid Osym operators to a LacI tetramer: evidence for contributions of non-operator DNA binding by wrapping and looping. J Mol Biol (1996) 1.12
Direct evidence for the preferential binding of Escherichia coli RNA polymerase holoenzyme to the ends of deoxyribonucleic acid restriction fragments. Biochemistry (1983) 1.11
Accumulation of 3-(N-morpholino)propanesulfonate by osmotically stressed Escherichia coli K-12. J Bacteriol (1989) 1.11
Characterization of rodlike RNA fragments. Biopolymers (1975) 1.10
Wrapping of flanking non-operator DNA in lac repressor-operator complexes: implications for DNA looping. J Mol Biol (1999) 1.09
23Na NMR relaxation study of the effects of conformation and base composition on the interactions of counterions with double-helical DNA. Biochemistry (1984) 1.09
Competitive interactions of Co(NH3)6(3+) and Na+ with helical B-DNA probed by 59Co and 23Na NMR. Biochemistry (1987) 1.07
Thermodynamic characterization of interactions of native bovine serum albumin with highly excluded (glycine betaine) and moderately accumulated (urea) solutes by a novel application of vapor pressure osmometry. Biochemistry (1996) 1.07
Measurement of binding constants for protein-DNA interactions by DNA-cellulose chromatography. Biochemistry (1977) 1.03
Compensating effects of opposing changes in putrescine (2+) and K+ concentrations on lac repressor-lac operator binding: in vitro thermodynamic analysis and in vivo relevance. J Mol Biol (1996) 1.03
Roles of Mg2+ in the mechanism of formation and dissociation of open complexes between Escherichia coli RNA polymerase and the lambda PR promoter: kinetic evidence for a second open complex requiring Mg2+. Biochemistry (1992) 1.02
Large electrostatic differences in the binding thermodynamics of a cationic peptide to oligomeric and polymeric DNA. Proc Natl Acad Sci U S A (1996) 1.02
Relative affinities of divalent polyamines and of their N-methylated analogues for helical DNA determined by 23Na NMR. Biochemistry (1991) 1.02
23Na-NMR investigations of counterion exchange reactions of helical DNA. Biopolymers (1986) 1.01
Ion effects on the aggregation and DNA-binding reactions of Escherichia coli RNA polymerase. Cold Spring Harb Symp Quant Biol (1983) 1.00
Binding of Escherichia coli ribonucleic acid polymerase holoenzyme to a bacteriophage T7 promoter-containing fragment: evaluation of promoter binding constants as a function of solution conditions. Biochemistry (1980) 1.00
Binding of Escherichia coli ribonucleic acid polymerase holoenzyme to a bacteriophage T7 promoter-containing fragment: selectivity exists over a wide range of solution conditions. Biochemistry (1980) 1.00
Interaction of an N-methylated polyamine analogue, hexamethonium(2+), with NaDNA: quantitative 14N and 23Na NMR relaxation rate studies of the cation-exchange process. Biochemistry (1988) 0.99
Kinetics of the helix-coil transition in DNA. Biopolymers (1972) 0.99
Analysis of ion concentration effects of the kinetics of protein-nucleic acid interactions. Application to lac repressor-operator interactions. Biophys Chem (1978) 0.99
Binding of cationic (+4) alanine- and glycine-containing oligopeptides to double-stranded DNA: thermodynamic analysis of effects of coulombic interactions and alpha-helix induction. Biochemistry (1997) 0.97
Quantifying accumulation or exclusion of H(+), HO(-), and Hofmeister salt ions near interfaces. Chem Phys Lett (2008) 0.95
Aggregation equilibria of Escherichia coli RNA polymerase: evidence for anion-linked conformational transitions in the protomers of core and holoenzyme. Biochemistry (1982) 0.95
E. coli promoter spacer regions contain nonrandom sequences which correlate to spacer length. Nucleic Acids Res (1990) 0.94
Counterion exchange reactions on DNA: Monte Carlo and Poisson-Boltzmann analysis. Biopolymers (1988) 0.93
The strand-separation transition of T2 bacteriophage DNA. Biopolymers (1974) 0.92
Quantitative analysis of multiple-hit footprinting studies to characterize DNA conformational changes in protein-DNA complexes: application to DNA opening by Esigma70 RNA polymerase. J Mol Biol (1998) 0.91
Preferential interactions between small solutes and the protein backbone: a computational analysis. Biochemistry (2010) 0.87
The strand-separation transition of T7 DNA. Biopolymers (1974) 0.86
Use of difference boundary sedimentation velocity to investigate nonspecific protein-nucleic acid interactions. Biochemistry (1980) 0.85
Thermodynamic investigation of hirudin binding to the slow and fast forms of thrombin: evidence for folding transitions in the inhibitor and protease coupled to binding. J Mol Biol (1995) 0.85
A method for horizontal polyacrylamide slab gel electrophoresis. Biotechniques (1989) 0.82
K(+)-ribosome interactions determine the large enhancements of 39K NMR transverse relaxation rates in the cytoplasm of Escherichia coli K-12. Biochemistry (1995) 0.81
Association kinetics of site-specific protein-DNA interactions: roles of nonspecific DNA sites and of the molecular location of the specific site. Biopolymers (1989) 0.78