PubRank

Howard Robinson

Author PubWeight™ 136.24‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Structural and biochemical studies of ALIX/AIP1 and its role in retrovirus budding. Cell 2007 3.06
2 The 1.9 A structure of a proteasome-11S activator complex and implications for proteasome-PAN/PA700 interactions. Mol Cell 2005 2.68
3 The crystal structure of Mtr4 reveals a novel arch domain required for rRNA processing. EMBO J 2010 2.25
4 Structure and ubiquitin binding of the ubiquitin-interacting motif. J Biol Chem 2003 2.19
5 The Fas-FADD death domain complex structure unravels signalling by receptor clustering. Nature 2008 2.11
6 AlgK is a TPR-containing protein and the periplasmic component of a novel exopolysaccharide secretin. Structure 2010 1.97
7 Structure of the antiviral assembly inhibitor CAP-1 complex with the HIV-1 CA protein. J Mol Biol 2007 1.78
8 Time-dependent, protein-directed growth of gold nanoparticles within a single crystal of lysozyme. Nat Nanotechnol 2011 1.77
9 Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation. J Am Chem Soc 2009 1.75
10 Crystal structure of DJ-1/RS and implication on familial Parkinson's disease. FEBS Lett 2003 1.73
11 Structure of the mid-region of tropomyosin: bending and binding sites for actin. Proc Natl Acad Sci U S A 2005 1.72
12 Rationally tuning the reduction potential of a single cupredoxin beyond the natural range. Nature 2009 1.68
13 Rational design of a structural and functional nitric oxide reductase. Nature 2009 1.60
14 Structural studies of a bacterial condensin complex reveal ATP-dependent disruption of intersubunit interactions. Cell 2009 1.58
15 A dimerized coiled-coil domain and an adjoining part of geminin interact with two sites on Cdt1 for replication inhibition. Mol Cell 2004 1.48
16 Implications for viral capsid assembly from crystal structures of HIV-1 Gag(1-278) and CA(N)(133-278). Biochemistry 2006 1.41
17 Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain. Nat Struct Mol Biol 2006 1.41
18 The refined crystal structure of an eel pout type III antifreeze protein RD1 at 0.62-A resolution reveals structural microheterogeneity of protein and solvation. Biophys J 2003 1.36
19 Structure of a Blm10 complex reveals common mechanisms for proteasome binding and gate opening. Mol Cell 2010 1.36
20 Roles of glutamates and metal ions in a rationally designed nitric oxide reductase based on myoglobin. Proc Natl Acad Sci U S A 2010 1.29
21 Multiple conformations of phosphodiesterase-5: implications for enzyme function and drug development. J Biol Chem 2006 1.29
22 Multiple elements jointly determine inhibitor selectivity of cyclic nucleotide phosphodiesterases 4 and 7. J Biol Chem 2005 1.25
23 Structural insight into substrate specificity of phosphodiesterase 10. Proc Natl Acad Sci U S A 2007 1.22
24 Crystal structures of the BlaI repressor from Staphylococcus aureus and its complex with DNA: insights into transcriptional regulation of the bla and mec operons. J Bacteriol 2005 1.19
25 Structural models for interactions between the 20S proteasome and its PAN/19S activators. J Biol Chem 2009 1.17
26 Crystal structure and RNA binding of the Tex protein from Pseudomonas aeruginosa. J Mol Biol 2008 1.15
27 Crystal structure of phosphodiesterase 9 shows orientation variation of inhibitor 3-isobutyl-1-methylxanthine binding. Proc Natl Acad Sci U S A 2004 1.14
28 Structure of the cytoplasmic region of PelD, a degenerate diguanylate cyclase receptor that regulates exopolysaccharide production in Pseudomonas aeruginosa. J Biol Chem 2012 1.11
29 Structural basis for alginate secretion across the bacterial outer membrane. Proc Natl Acad Sci U S A 2011 1.11
30 Kinetic and structural studies of phosphodiesterase-8A and implication on the inhibitor selectivity. Biochemistry 2008 1.09
31 Crystal structure of the pyocyanin biosynthetic protein PhzS. Biochemistry 2008 1.08
32 Crystal structure of the [Mg2+-(chromomycin A3)2]-d(TTGGCCAA)2 complex reveals GGCC binding specificity of the drug dimer chelated by a metal ion. Nucleic Acids Res 2004 1.08
33 Crystal structure of Haemophilus influenzae NadR protein. A bifunctional enzyme endowed with NMN adenyltransferase and ribosylnicotinimide kinase activities. J Biol Chem 2002 1.07
34 Identification and structural characterization of the ALIX-binding late domains of simian immunodeficiency virus SIVmac239 and SIVagmTan-1. J Virol 2010 1.06
35 The peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics. J Immunol 2012 1.05
36 Characterization of two potentially universal turn motifs that shape the repeated five-residues fold--crystal structure of a lumenal pentapeptide repeat protein from Cyanothece 51142. Protein Sci 2006 1.05
37 Structural and functional analysis of the pyocyanin biosynthetic protein PhzM from Pseudomonas aeruginosa. Biochemistry 2007 1.04
38 Structural insights into membrane targeting by the flagellar calcium-binding protein (FCaBP), a myristoylated and palmitoylated calcium sensor in Trypanosoma cruzi. J Biol Chem 2008 1.02
39 Alternative conformations of the archaeal Nop56/58-fibrillarin complex imply flexibility in box C/D RNPs. J Mol Biol 2007 1.02
40 Impaired acid catalysis by mutation of a protein loop hinge residue in a YopH mutant revealed by crystal structures. J Am Chem Soc 2009 1.01
41 Profound asymmetry in the structure of the cAMP-free cAMP Receptor Protein (CRP) from Mycobacterium tuberculosis. J Biol Chem 2009 1.01
42 Crystal structure of human kynurenine aminotransferase II. J Biol Chem 2007 1.00
43 Structures of the four subfamilies of phosphodiesterase-4 provide insight into the selectivity of their inhibitors. Biochem J 2007 1.00
44 A designed functional metalloenzyme that reduces O2 to H2O with over one thousand turnovers. Angew Chem Int Ed Engl 2012 1.00
45 Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II. Biosci Rep 2008 0.99
46 Biochemical and structural properties of mouse kynurenine aminotransferase III. Mol Cell Biol 2008 0.98
47 Structural mechanism for inactivation and activation of CAD/DFF40 in the apoptotic pathway. Mol Cell 2004 0.98
48 Structure of the Spt16 middle domain reveals functional features of the histone chaperone FACT. J Biol Chem 2013 0.98
49 NSP-Cas protein structures reveal a promiscuous interaction module in cell signaling. Nat Struct Mol Biol 2011 0.97
50 Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK. Nat Commun 2013 0.96
51 The structure- and metal-dependent activity of Escherichia coli PgaB provides insight into the partial de-N-acetylation of poly-β-1,6-N-acetyl-D-glucosamine. J Biol Chem 2012 0.96
52 Crystal structure of actinomycin D bound to the CTG triplet repeat sequences linked to neurological diseases. Nucleic Acids Res 2002 0.96
53 Visualizing key hinges and a potential major source of compliance in the lever arm of myosin. Proc Natl Acad Sci U S A 2010 0.96
54 Crystal structures of Aedes aegypti alanine glyoxylate aminotransferase. J Biol Chem 2006 0.96
55 Crystal structure of the oxygen-dependant coproporphyrinogen oxidase (Hem13p) of Saccharomyces cerevisiae. J Biol Chem 2004 0.96
56 Introducing a 2-His-1-Glu nonheme iron center into myoglobin confers nitric oxide reductase activity. J Am Chem Soc 2010 0.95
57 Systematic tuning of heme redox potentials and its effects on O2 reduction rates in a designed oxidase in myoglobin. J Am Chem Soc 2014 0.95
58 Beamline X29: a novel undulator source for X-ray crystallography. J Synchrotron Radiat 2006 0.95
59 Crystal structure of the murine cytomegalovirus MHC-I homolog m144. J Mol Biol 2006 0.93
60 Identification, structural, and biochemical characterization of a group of large Csn2 proteins involved in CRISPR-mediated bacterial immunity. Proteins 2012 0.93
61 Crystal structure and substrate specificity of Drosophila 3,4-dihydroxyphenylalanine decarboxylase. PLoS One 2010 0.92
62 Different vaccine vectors delivering the same antigen elicit CD8+ T cell responses with distinct clonotype and epitope specificity. J Immunol 2009 0.92
63 Conformational variations of both phosphodiesterase-5 and inhibitors provide the structural basis for the physiological effects of vardenafil and sildenafil. Mol Pharmacol 2007 0.92
64 Structure of the Chlamydia protein CADD reveals a redox enzyme that modulates host cell apoptosis. J Biol Chem 2004 0.92
65 Crystal structures of the S. cerevisiae Spt6 core and C-terminal tandem SH2 domain. J Mol Biol 2011 0.91
66 Structure of PqsD, a Pseudomonas quinolone signal biosynthetic enzyme, in complex with anthranilate. Biochemistry 2009 0.91
67 Structure of the F-spondin domain of mindin, an integrin ligand and pattern recognition molecule. EMBO J 2009 0.91
68 Structure of the class IV adenylyl cyclase reveals a novel fold. J Mol Biol 2006 0.90
69 The molecular basis for different recognition of substrates by phosphodiesterase families 4 and 10. J Mol Biol 2007 0.90
70 A 1.7A structure of Fve, a member of the new fungal immunomodulatory protein family. J Mol Biol 2003 0.90
71 Structural insight into the inhibition of human kynurenine aminotransferase I/glutamine transaminase K. J Med Chem 2009 0.89
72 Structure of 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase from Shewanella oneidensis at 1.6 A: identification of farnesyl pyrophosphate trapped in a hydrophobic cavity. Acta Crystallogr D Biol Crystallogr 2004 0.89
73 Crystal structure of the receptor binding domain of the botulinum C-D mosaic neurotoxin reveals potential roles of lysines 1118 and 1136 in membrane interactions. Biochem Biophys Res Commun 2010 0.89
74 Human glutathione-dependent formaldehyde dehydrogenase. Structures of apo, binary, and inhibitory ternary complexes. Biochemistry 2002 0.89
75 Structural analysis of Pseudomonas 1-aminocyclopropane-1-carboxylate deaminase complexes: insight into the mechanism of a unique pyridoxal-5'-phosphate dependent cyclopropane ring-opening reaction. Biochemistry 2004 0.89
76 Structural insights into the regulation of foreign genes in Salmonella by the Hha/H-NS complex. J Biol Chem 2013 0.89
77 Structural and functional characterization of Pseudomonas aeruginosa AlgX: role of AlgX in alginate acetylation. J Biol Chem 2013 0.89
78 Redesigning the blue copper azurin into a redox-active mononuclear nonheme iron protein: preparation and study of Fe(II)-M121E azurin. J Am Chem Soc 2014 0.88
79 Insights into the structural variation between pentapeptide repeat proteins--crystal structure of Rfr23 from Cyanothece 51142. J Struct Biol 2007 0.88
80 Structural analysis of the receptor binding domain of botulinum neurotoxin serotype D. Biochem Biophys Res Commun 2010 0.87
81 A comparative biochemical and structural analysis of the intracellular chorismate mutase (Rv0948c) from Mycobacterium tuberculosis H(37)R(v) and the secreted chorismate mutase (y2828) from Yersinia pestis. FEBS J 2008 0.87
82 Structure of a proteasome Pba1-Pba2 complex: implications for proteasome assembly, activation, and biological function. J Biol Chem 2012 0.87
83 Plant hemoglobins: a molecular fossil record for the evolution of oxygen transport. J Mol Biol 2007 0.87
84 Tyrosine aminotransferase: biochemical and structural properties and molecular dynamics simulations. Protein Cell 2010 0.86
85 Conformation changes, N-terminal involvement, and cGMP signal relay in the phosphodiesterase-5 GAF domain. J Biol Chem 2010 0.86
86 Biological and structural characterization of Trypanosoma cruzi phosphodiesterase C and Implications for design of parasite selective inhibitors. J Biol Chem 2012 0.86
87 Structural basis of mouse cytomegalovirus m152/gp40 interaction with RAE1γ reveals a paradigm for MHC/MHC interaction in immune evasion. Proc Natl Acad Sci U S A 2012 0.85
88 Crystallization and preliminary X-ray diffraction study of the farnesyl diphosphate synthase from Trypanosoma brucei. Acta Crystallogr D Biol Crystallogr 2004 0.85
89 High-level expression, purification, crystallization and preliminary X-ray crystallographic studies of the receptor-binding domain of botulinum neurotoxin serotype D. Acta Crystallogr Sect F Struct Biol Cryst Commun 2010 0.85
90 Cellular expression and crystal structure of the murine cytomegalovirus major histocompatibility complex class I-like glycoprotein, m153. J Biol Chem 2007 0.85
91 Structural evidence suggests that antiactivator ExsD from Pseudomonas aeruginosa is a DNA binding protein. Protein Sci 2009 0.84
92 Combining in situ proteolysis and mass spectrometry to crystallize Escherichia coli PgaB. Acta Crystallogr Sect F Struct Biol Cryst Commun 2012 0.84
93 Structure determination and functional analysis of a chromate reductase from Gluconacetobacter hansenii. PLoS One 2012 0.83
94 Structural insight into the mechanism of substrate specificity of aedes kynurenine aminotransferase. Biochemistry 2008 0.83
95 Structure of the Bro1 domain protein BROX and functional analyses of the ALIX Bro1 domain in HIV-1 budding. PLoS One 2011 0.83
96 Crystal structures of Aedes aegypti kynurenine aminotransferase. FEBS J 2005 0.83
97 Biochemical identification and crystal structure of kynurenine formamidase from Drosophila melanogaster. Biochem J 2012 0.82
98 Insight into binding of phosphodiesterase-9A selective inhibitors by crystal structures and mutagenesis. J Med Chem 2010 0.82
99 Structure of C73G putidaredoxin from Pseudomonas putida. Acta Crystallogr D Biol Crystallogr 2004 0.82
100 Crystallization and phasing of alanine dehydrogenase from Archaeoglobus fulgidus. Acta Crystallogr D Biol Crystallogr 2003 0.82
101 Purification, crystallization and preliminary X-ray crystallographic analysis of squid heavy meromyosin. Acta Crystallogr Sect F Struct Biol Cryst Commun 2013 0.81
102 Biochemical and structural characterization of mouse mitochondrial aspartate aminotransferase, a newly identified kynurenine aminotransferase-IV. Biosci Rep 2011 0.81
103 Crystal structure of staphylococcal enterotoxin G (SEG) in complex with a mouse T-cell receptor {beta} chain. J Biol Chem 2010 0.81
104 Functional and structural characterization of DR_0079 from Deinococcus radiodurans, a novel Nudix hydrolase with a preference for cytosine (deoxy)ribonucleoside 5'-Di- and triphosphates. Biochemistry 2008 0.80
105 Expression, purification, crystallization and preliminary X-ray analysis of Pseudomonas aeruginosa PelD. Acta Crystallogr Sect F Struct Biol Cryst Commun 2012 0.80
106 Expression, purification, crystallization and preliminary X-ray analysis of Pseudomonas aeruginosa AlgL. Acta Crystallogr Sect F Struct Biol Cryst Commun 2012 0.80
107 Crystal structure of a macrophage migration inhibitory factor from Giardia lamblia. J Struct Funct Genomics 2013 0.80
108 Kinetic and crystallographic studies of a redesigned manganese-binding site in cytochrome c peroxidase. J Biol Inorg Chem 2006 0.80
109 Enantiomer discrimination illustrated by the high resolution crystal structures of type 4 phosphodiesterase. J Med Chem 2006 0.79
110 Structure of the D-alanylgriseoluteic acid biosynthetic protein EhpF, an atypical member of the ANL superfamily of adenylating enzymes. Acta Crystallogr D Biol Crystallogr 2010 0.79
111 Catalytic mechanism and mode of action of the periplasmic alginate epimerase AlgG. J Biol Chem 2014 0.79
112 Structure-function relationships in human glutathione-dependent formaldehyde dehydrogenase. Role of Glu-67 and Arg-368 in the catalytic mechanism. Biochemistry 2006 0.79
113 An insight into the pharmacophores of phosphodiesterase-5 inhibitors from synthetic and crystal structural studies. Biochem Pharmacol 2008 0.79
114 Active-site structure of class IV adenylyl cyclase and transphyletic mechanism. J Mol Biol 2010 0.79
115 Crystal structure of VC0702 at 2.0 A: conserved hypothetical protein from Vibrio cholerae. Proteins 2006 0.78
116 Crystal structure of a phosphorylated light chain domain of scallop smooth-muscle myosin. Biophys J 2011 0.78
117 Expression, purification, crystallization and preliminary X-ray analysis of Pseudomonas aeruginosa AlgX. Acta Crystallogr Sect F Struct Biol Cryst Commun 2010 0.78
118 A structural and molecular dynamics approach to understanding the peptide-receptive transition state of MHC-I molecules. Mol Immunol 2012 0.78
119 Structural characterization of the protein cce_0567 from Cyanothece 51142, a metalloprotein associated with nitrogen fixation in the DUF683 family. Biochim Biophys Acta 2009 0.78
120 Evolution of insect arylalkylamine N-acetyltransferases: structural evidence from the yellow fever mosquito, Aedes aegypti. Proc Natl Acad Sci U S A 2012 0.78
121 Automated high-throughput nanoliter-scale protein crystallization screening. Anal Bioanal Chem 2005 0.77
122 Structure-function relationships in human Class III alcohol dehydrogenase (formaldehyde dehydrogenase). Chem Biol Interact 2003 0.77
123 Structural insights into the functional role of the Hcn sub-domain of the receptor-binding domain of the botulinum neurotoxin mosaic serotype C/D. Biochimie 2013 0.77
124 Can protein conformers be fractionated by crystallization? Anal Chem 2013 0.77
125 Expression, purification, crystallization and preliminary X-ray analysis of Pseudomonas fluorescens AlgK. Acta Crystallogr Sect F Struct Biol Cryst Commun 2007 0.77
126 Structural characterization of Burkholderia pseudomallei adenylate kinase (Adk): profound asymmetry in the crystal structure of the 'open' state. Biochem Biophys Res Commun 2010 0.77
127 Biochemical characterization and crystal structure of a GH10 xylanase from termite gut bacteria reveal a novel structural feature and significance of its bacterial Ig-like domain. Biotechnol Bioeng 2013 0.76
128 Cloning, expression, crystallization and preliminary crystallographic analysis of a pentapeptide-repeat protein (Rfr23) from the bacterium Cyanothece 51142. Acta Crystallogr Sect F Struct Biol Cryst Commun 2006 0.76
129 The structure at 2.5 A resolution of human basophilic leukemia-expressed protein BLES03. Acta Crystallogr Sect F Struct Biol Cryst Commun 2005 0.76
130 Protein Crystal Engineering of YpAC-IV using the Strategy of Excess Charge Reduction. Cryst Growth Des 2009 0.75
131 Dual specificity and novel structural folding of yeast phosphodiesterase-1 for hydrolysis of second messengers cyclic adenosine and guanosine 3',5'-monophosphate. Biochemistry 2014 0.75
132 Crystal structure of cce_0566 from Cyanothece 51142, a protein associated with nitrogen fixation in the DUF269 family. FEBS Lett 2012 0.75
133 Structural Basis for the Activation and Inhibition of the UCH37 Deubiquitylase. Mol Cell 2016 0.75