Published in EMBO J on May 28, 2010
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TRAMP complex enhances RNA degradation by the nuclear exosome component Rrp6. J Biol Chem (2009) 1.39
A nuclear surveillance pathway for mRNAs with defective polyadenylation. Mol Cell Biol (2005) 1.39
Structural basis for the function of DEAH helicases. EMBO Rep (2010) 1.34
Distinct roles of non-canonical poly(A) polymerases in RNA metabolism. PLoS Genet (2009) 1.33
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The exosome and the proteasome: nano-compartments for degradation. Cell (2006) 1.17
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Characterization of the essential activities of Saccharomyces cerevisiae Mtr4p, a 3'->5' helicase partner of the nuclear exosome. J Biol Chem (2007) 1.13
Atomic structures and functional implications of the archaeal RecQ-like helicase Hjm. BMC Struct Biol (2009) 0.98
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Rationally tuning the reduction potential of a single cupredoxin beyond the natural range. Nature (2009) 1.68
Rational design of a structural and functional nitric oxide reductase. Nature (2009) 1.60
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Modulating the RNA processing and decay by the exosome: altering Rrp44/Dis3 activity and end-product. PLoS One (2013) 1.48
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Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain. Nat Struct Mol Biol (2006) 1.41
The refined crystal structure of an eel pout type III antifreeze protein RD1 at 0.62-A resolution reveals structural microheterogeneity of protein and solvation. Biophys J (2003) 1.36
Structure of a Blm10 complex reveals common mechanisms for proteasome binding and gate opening. Mol Cell (2010) 1.36
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Multiple conformations of phosphodiesterase-5: implications for enzyme function and drug development. J Biol Chem (2006) 1.29
A genomic screen in yeast reveals novel aspects of nonstop mRNA metabolism. Genetics (2007) 1.26
Multiple elements jointly determine inhibitor selectivity of cyclic nucleotide phosphodiesterases 4 and 7. J Biol Chem (2005) 1.25
Structural insight into substrate specificity of phosphodiesterase 10. Proc Natl Acad Sci U S A (2007) 1.22
Crystal structures of the BlaI repressor from Staphylococcus aureus and its complex with DNA: insights into transcriptional regulation of the bla and mec operons. J Bacteriol (2005) 1.19
Different nuclease requirements for exosome-mediated degradation of normal and nonstop mRNAs. Proc Natl Acad Sci U S A (2011) 1.18
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Crystal structure and RNA binding of the Tex protein from Pseudomonas aeruginosa. J Mol Biol (2008) 1.15
Crystal structure of phosphodiesterase 9 shows orientation variation of inhibitor 3-isobutyl-1-methylxanthine binding. Proc Natl Acad Sci U S A (2004) 1.14
Nonsense-mediated mRNA decay in yeast does not require PAB1 or a poly(A) tail. Mol Cell (2008) 1.14
Structure of the cytoplasmic region of PelD, a degenerate diguanylate cyclase receptor that regulates exopolysaccharide production in Pseudomonas aeruginosa. J Biol Chem (2012) 1.11
Structural basis for alginate secretion across the bacterial outer membrane. Proc Natl Acad Sci U S A (2011) 1.11
Insights into the reaction of protein-tyrosine phosphatase 1B: crystal structures for transition state analogs of both catalytic steps. J Biol Chem (2010) 1.10
Kinetic and structural studies of phosphodiesterase-8A and implication on the inhibitor selectivity. Biochemistry (2008) 1.09
Genetic interactions between [PSI+] and nonstop mRNA decay affect phenotypic variation. Proc Natl Acad Sci U S A (2005) 1.09
Crystal structure of the pyocyanin biosynthetic protein PhzS. Biochemistry (2008) 1.08
Crystal structure of the [Mg2+-(chromomycin A3)2]-d(TTGGCCAA)2 complex reveals GGCC binding specificity of the drug dimer chelated by a metal ion. Nucleic Acids Res (2004) 1.08
Crystal structure of Haemophilus influenzae NadR protein. A bifunctional enzyme endowed with NMN adenyltransferase and ribosylnicotinimide kinase activities. J Biol Chem (2002) 1.07
Identification and structural characterization of the ALIX-binding late domains of simian immunodeficiency virus SIVmac239 and SIVagmTan-1. J Virol (2010) 1.06
The peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics. J Immunol (2012) 1.05
Characterization of two potentially universal turn motifs that shape the repeated five-residues fold--crystal structure of a lumenal pentapeptide repeat protein from Cyanothece 51142. Protein Sci (2006) 1.05
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Structural and functional analysis of the pyocyanin biosynthetic protein PhzM from Pseudomonas aeruginosa. Biochemistry (2007) 1.04
Structural insights into membrane targeting by the flagellar calcium-binding protein (FCaBP), a myristoylated and palmitoylated calcium sensor in Trypanosoma cruzi. J Biol Chem (2008) 1.02
Alternative conformations of the archaeal Nop56/58-fibrillarin complex imply flexibility in box C/D RNPs. J Mol Biol (2007) 1.02
Profound asymmetry in the structure of the cAMP-free cAMP Receptor Protein (CRP) from Mycobacterium tuberculosis. J Biol Chem (2009) 1.01
Impaired acid catalysis by mutation of a protein loop hinge residue in a YopH mutant revealed by crystal structures. J Am Chem Soc (2009) 1.01
Crystal structure of human kynurenine aminotransferase II. J Biol Chem (2007) 1.00
Structures of the four subfamilies of phosphodiesterase-4 provide insight into the selectivity of their inhibitors. Biochem J (2007) 1.00
A designed functional metalloenzyme that reduces O2 to H2O with over one thousand turnovers. Angew Chem Int Ed Engl (2012) 1.00
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Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II. Biosci Rep (2008) 0.99
Structural mechanism for inactivation and activation of CAD/DFF40 in the apoptotic pathway. Mol Cell (2004) 0.98
Biochemical and structural properties of mouse kynurenine aminotransferase III. Mol Cell Biol (2008) 0.98
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Visualizing key hinges and a potential major source of compliance in the lever arm of myosin. Proc Natl Acad Sci U S A (2010) 0.96
The structure- and metal-dependent activity of Escherichia coli PgaB provides insight into the partial de-N-acetylation of poly-β-1,6-N-acetyl-D-glucosamine. J Biol Chem (2012) 0.96
Crystal structure of actinomycin D bound to the CTG triplet repeat sequences linked to neurological diseases. Nucleic Acids Res (2002) 0.96
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Crystal structure of the oxygen-dependant coproporphyrinogen oxidase (Hem13p) of Saccharomyces cerevisiae. J Biol Chem (2004) 0.96
Introducing a 2-His-1-Glu nonheme iron center into myoglobin confers nitric oxide reductase activity. J Am Chem Soc (2010) 0.95
Beamline X29: a novel undulator source for X-ray crystallography. J Synchrotron Radiat (2006) 0.95
Systematic tuning of heme redox potentials and its effects on O2 reduction rates in a designed oxidase in myoglobin. J Am Chem Soc (2014) 0.95
Crystal structure of the murine cytomegalovirus MHC-I homolog m144. J Mol Biol (2006) 0.93
The CR3 motif of Rrp44p is important for interaction with the core exosome and exosome function. Nucleic Acids Res (2012) 0.93
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Crystal structure and substrate specificity of Drosophila 3,4-dihydroxyphenylalanine decarboxylase. PLoS One (2010) 0.92
Conformational variations of both phosphodiesterase-5 and inhibitors provide the structural basis for the physiological effects of vardenafil and sildenafil. Mol Pharmacol (2007) 0.92
Different vaccine vectors delivering the same antigen elicit CD8+ T cell responses with distinct clonotype and epitope specificity. J Immunol (2009) 0.92
Structure of the Chlamydia protein CADD reveals a redox enzyme that modulates host cell apoptosis. J Biol Chem (2004) 0.92
Crystal structures of the S. cerevisiae Spt6 core and C-terminal tandem SH2 domain. J Mol Biol (2011) 0.91
Structure of the F-spondin domain of mindin, an integrin ligand and pattern recognition molecule. EMBO J (2009) 0.91
Structure of PqsD, a Pseudomonas quinolone signal biosynthetic enzyme, in complex with anthranilate. Biochemistry (2009) 0.91
The molecular basis for different recognition of substrates by phosphodiesterase families 4 and 10. J Mol Biol (2007) 0.90
Structure of the class IV adenylyl cyclase reveals a novel fold. J Mol Biol (2006) 0.90
A 1.7A structure of Fve, a member of the new fungal immunomodulatory protein family. J Mol Biol (2003) 0.90
Structural insight into the inhibition of human kynurenine aminotransferase I/glutamine transaminase K. J Med Chem (2009) 0.89
Structural analysis of Pseudomonas 1-aminocyclopropane-1-carboxylate deaminase complexes: insight into the mechanism of a unique pyridoxal-5'-phosphate dependent cyclopropane ring-opening reaction. Biochemistry (2004) 0.89
Human glutathione-dependent formaldehyde dehydrogenase. Structures of apo, binary, and inhibitory ternary complexes. Biochemistry (2002) 0.89
Structural insights into the regulation of foreign genes in Salmonella by the Hha/H-NS complex. J Biol Chem (2013) 0.89
Structure of 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase from Shewanella oneidensis at 1.6 A: identification of farnesyl pyrophosphate trapped in a hydrophobic cavity. Acta Crystallogr D Biol Crystallogr (2004) 0.89
Crystal structure of the receptor binding domain of the botulinum C-D mosaic neurotoxin reveals potential roles of lysines 1118 and 1136 in membrane interactions. Biochem Biophys Res Commun (2010) 0.89
Structural and functional characterization of Pseudomonas aeruginosa AlgX: role of AlgX in alginate acetylation. J Biol Chem (2013) 0.89
Redesigning the blue copper azurin into a redox-active mononuclear nonheme iron protein: preparation and study of Fe(II)-M121E azurin. J Am Chem Soc (2014) 0.88
Insights into the structural variation between pentapeptide repeat proteins--crystal structure of Rfr23 from Cyanothece 51142. J Struct Biol (2007) 0.88
Structural analysis of the receptor binding domain of botulinum neurotoxin serotype D. Biochem Biophys Res Commun (2010) 0.87
Structure of a proteasome Pba1-Pba2 complex: implications for proteasome assembly, activation, and biological function. J Biol Chem (2012) 0.87
Plant hemoglobins: a molecular fossil record for the evolution of oxygen transport. J Mol Biol (2007) 0.87