Published in Dev Cell on March 16, 2010
The SYK tyrosine kinase: a crucial player in diverse biological functions. Nat Rev Immunol (2010) 4.26
Lymphatic vascular morphogenesis in development, physiology, and disease. J Cell Biol (2011) 2.29
A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy. EMBO J (2013) 1.58
CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development. Blood (2011) 1.30
The role of chemokines and their receptors in angiogenesis. Cell Mol Life Sci (2011) 1.15
Deletion of Syk in neutrophils prevents immune complex arthritis. J Immunol (2011) 1.15
Deciphering the roles of macrophages in developmental and inflammation stimulated lymphangiogenesis. Vasc Cell (2012) 1.01
The chemokine receptors ACKR2 and CCR2 reciprocally regulate lymphatic vessel density. EMBO J (2014) 0.95
The physiological and pathophysiological roles of platelet CLEC-2. Thromb Haemost (2013) 0.92
Spleen tyrosine kinase inhibition in the treatment of autoimmune, allergic and autoinflammatory diseases. Arthritis Res Ther (2010) 0.88
Myeloid cells and lymphangiogenesis. Cold Spring Harb Perspect Med (2012) 0.88
Platelet immunoreceptor tyrosine-based activation motif (ITAM) signaling and vascular integrity. Circ Res (2014) 0.87
Fusing VE-cadherin to α-catenin impairs fetal liver hematopoiesis and lymph but not blood vessel formation. Mol Cell Biol (2014) 0.85
Syk and Src family kinases regulate C-type lectin receptor 2 (CLEC-2)-mediated clustering of podoplanin and platelet adhesion to lymphatic endothelial cells. J Biol Chem (2014) 0.85
Podoplanin and CLEC-2 drive cerebrovascular patterning and integrity during development. Blood (2015) 0.85
A PREVIOUSLY UNKNOWN UNIQUE CHALLENGE FOR INHIBITORS OF SYK ATP-BINDING SITE: ROLE OF SYK AS A CELL CYCLE CHECKPOINT REGULATOR. EBioMedicine (2014) 0.83
Adiponectin regulates vascular endothelial growth factor-C expression in macrophages via Syk-ERK pathway. PLoS One (2013) 0.81
Altered BCR signalling quality predisposes to autoimmune disease and a pre-diabetic state. EMBO J (2012) 0.81
Pharmacological manipulation of blood and lymphatic vascularization in ex vivo-cultured mouse embryos. Nat Protoc (2012) 0.79
The N-terminal SH2 domain of Syk is required for (hem)ITAM, but not integrin, signaling in mouse platelets. Blood (2014) 0.79
Integration of CD45-positive leukocytes into newly forming lymphatics of adult mice. Histochem Cell Biol (2016) 0.78
(Lymph)angiogenic influences on hematopoietic cells in acute myeloid leukemia. Exp Mol Med (2014) 0.78
Intestinal lymphatic vasculature: structure, mechanisms and functions. Nat Rev Gastroenterol Hepatol (2017) 0.78
Platelet adhesion to podoplanin under flow is mediated by the receptor CLEC-2 and stabilised by Src/Syk-dependent platelet signalling. Thromb Haemost (2015) 0.77
The BAFFling function of Syk in B-cell homeostasis. EMBO J (2015) 0.76
Tube-like structures with co-expression of D2-40 and CD34: newly formed vasculatures? Int J Biol Sci (2012) 0.76
The role of RNA interference in the developmental separation of blood and lymphatic vasculature. Vasc Cell (2014) 0.75
A novel model for ectopic, chronic, intravital multiphoton imaging of bone marrow vasculature and architecture in split femurs. Intravital (2015) 0.75
Phospholipase Cγ2 Is Required for Luminal Expansion of the Epididymal Duct during Postnatal Development in Mice. PLoS One (2016) 0.75
Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response. J Immunol (2004) 8.65
Epiblast stem cell subpopulations represent mouse embryos of distinct pregastrulation stages. Cell (2010) 2.58
Mechanotransduction, PROX1, and FOXC2 cooperate to control connexin37 and calcineurin during lymphatic-valve formation. Dev Cell (2012) 2.45
Induction of pluripotency in adult unipotent germline stem cells. Cell Stem Cell (2009) 2.26
BCR-ABL enhances differentiation of long-term repopulating hematopoietic stem cells. Blood (2010) 2.17
The junctional adhesion molecule (JAM) family members JAM-2 and JAM-3 associate with the cell polarity protein PAR-3: a possible role for JAMs in endothelial cell polarity. J Cell Sci (2003) 1.84
Stabilizing the VE-cadherin-catenin complex blocks leukocyte extravasation and vascular permeability. EMBO J (2011) 1.69
A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy. EMBO J (2013) 1.58
Direct reprogramming of fibroblasts into epiblast stem cells. Nat Cell Biol (2010) 1.52
Dual interaction of JAM-C with JAM-B and alpha(M)beta2 integrin: function in junctional complexes and leukocyte adhesion. Mol Biol Cell (2005) 1.45
Hematopoietic progenitor kinase 1 (HPK1) is required for LFA-1-mediated neutrophil recruitment during the acute inflammatory response. Blood (2013) 1.41
Pluripotential reprogramming of the somatic genome in hybrid cells occurs with the first cell cycle. Stem Cells (2007) 1.37
VE-PTP controls blood vessel development by balancing Tie-2 activity. J Cell Biol (2009) 1.32
Identification of a clonally expanding haematopoietic compartment in bone marrow. EMBO J (2012) 1.19
Activation of hematopoietic progenitor kinase 1 involves relocation, autophosphorylation, and transphosphorylation by protein kinase D1. Mol Cell Biol (2005) 1.13
Smed-SmB, a member of the LSm protein superfamily, is essential for chromatoid body organization and planarian stem cell proliferation. Development (2010) 1.10
CCR7-mediated LFA-1 functions in T cells are regulated by 2 independent ADAP/SKAP55 modules. Blood (2011) 1.10
Troglitazone sensitizes tumor cells to TRAIL-induced apoptosis via down-regulation of FLIP and Survivin. Apoptosis (2006) 1.06
Conversion of adult mouse unipotent germline stem cells into pluripotent stem cells. Nat Protoc (2010) 1.06
Caspase-cleaved HPK1 induces CD95L-independent activation-induced cell death in T and B lymphocytes. Blood (2007) 1.05
Phosphorylation of CARMA1 by HPK1 is critical for NF-kappaB activation in T cells. Proc Natl Acad Sci U S A (2009) 1.02
Intravital two-photon microscopy of lymphatic vessel development and function using a transgenic Prox1 promoter-directed mOrange2 reporter mouse. Biochem Soc Trans (2011) 1.00
Synthesis and biological evaluation of novel exo-methylene cyclopentanone tetracyclic diterpenoids as antitumor agents. Bioorg Med Chem Lett (2010) 0.99
Activation or suppression of NFkappaB by HPK1 determines sensitivity to activation-induced cell death. EMBO J (2005) 0.99
Novel imatinib-sensitive PDGFRA-activating point mutations in hypereosinophilic syndrome induce growth factor independence and leukemia-like disease. Blood (2011) 0.98
Neural induction intermediates exhibit distinct roles of Fgf signaling. Stem Cells (2010) 0.97
Enhanced reprogramming of Xist by induced upregulation of Tsix and Dnmt3a. Stem Cells (2008) 0.97
Identification of genes specific to mouse primordial germ cells through dynamic global gene expression. Hum Mol Genet (2010) 0.96
Vascular endothelial insulin/IGF-1 signaling controls skin wound vascularization. Biochem Biophys Res Commun (2012) 0.92
Hydrothermal growth of large-scale micropatterned arrays of ultralong ZnO nanowires and nanobelts on zinc substrate. Chem Commun (Camb) (2006) 0.90
Tie1 deletion inhibits tumor growth and improves angiopoietin antagonist therapy. J Clin Invest (2014) 0.90
Discovery of inhibitors of microglial neurotoxicity acting through multiple mechanisms using a stem-cell-based phenotypic assay. Cell Stem Cell (2012) 0.89
FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature. J Clin Invest (2015) 0.89
Erasure of cellular memory by fusion with pluripotent cells. Stem Cells (2007) 0.88
AML1/ETO induces self-renewal in hematopoietic progenitor cells via the Groucho-related amino-terminal AES protein. Blood (2011) 0.86
Fusing VE-cadherin to α-catenin impairs fetal liver hematopoiesis and lymph but not blood vessel formation. Mol Cell Biol (2014) 0.85
Biological activities and corresponding SARs of andrographolide and its derivatives. Mini Rev Med Chem (2013) 0.85
Facile synthesis of monodisperse microspheres and gigantic hollow shells of mesoporous silica in mixed water-ethanol solvents. Langmuir (2007) 0.84
Pim2 cooperates with PML-RARalpha to induce acute myeloid leukemia in a bone marrow transplantation model. Blood (2010) 0.83
Migration inhibition of mammary epithelial cells by Syk is blocked in the presence of DDR1 receptors. Cell Mol Life Sci (2011) 0.83
In vitro differentiation of reprogrammed murine somatic cells into hepatic precursor cells. Biol Chem (2008) 0.81
Ischemic postconditioning downregulates Egr-1 expression and attenuates postischemic pulmonary inflammatory cytokine release and tissue injury in rats. J Surg Res (2012) 0.81
Altered BCR signalling quality predisposes to autoimmune disease and a pre-diabetic state. EMBO J (2012) 0.81
Hematopoietic progenitor kinase 1 is a critical component of prostaglandin E2-mediated suppression of the anti-tumor immune response. Cancer Immunol Immunother (2009) 0.80
Characterizing the interaction between the Rab6 GTPase and Mint3 via flow cytometry based FRET analysis. Biochem Biophys Res Commun (2010) 0.80
Modulation of synaptic function through the α-neurexin-specific ligand neurexophilin-1. Proc Natl Acad Sci U S A (2014) 0.79
Reprogramming of two somatic nuclei in the same ooplasm leads to pluripotent embryonic stem cells. Stem Cells (2013) 0.79
Visualization of lymphatic vessel development, growth, and function. Adv Anat Embryol Cell Biol (2014) 0.78
Effects of hydroperoxides on contractile reactivity and free radical production of porcine brain arteries. Gen Physiol Biophys (2009) 0.77
Phylogenetic analysis of the sequences of rDNA internal transcribed spacer (ITS) of Phytophthora sojae. J Genet Genomics (2007) 0.77
HPK1 competes with ADAP for SLP-76 binding and via Rap1 negatively affects T-cell adhesion. Eur J Immunol (2010) 0.77
HPK1 associates with SKAP-HOM to negatively regulate Rap1-mediated B-lymphocyte adhesion. PLoS One (2010) 0.77
Hematopoietic progenitor kinase 1 is a negative regulator of dendritic cell activation. J Immunol (2009) 0.77
[Effects of D-galactose on ageing of rat mesenchymal stem cells]. Zhejiang Da Xue Xue Bao Yi Xue Ban (2013) 0.76
A new Mint1 isoform, but not the conventional Mint1, interacts with the small GTPase Rab6. PLoS One (2013) 0.76
Suboptimal B-cell antigen receptor signaling activity in vivo elicits germinal center counterselection mechanisms. Eur J Immunol (2014) 0.75
kW-level narrow linewidth fiber amplifier seeded by a fiber Bragg grating based oscillator. Appl Opt (2015) 0.75
Fiber polarization control based on a fast locating algorithm. Appl Opt (2013) 0.75
Dynamic optical limiting experiments on vanadium dioxide and vanadium pentoxide thin films irradiated by a laser beam. Appl Opt (2006) 0.75
Biotransformation of 2alpha,5alpha,10beta,14beta-tetraacetoxy-4(20),11-taxadiene by cell suspension cultures of Catharanthus roseus. Planta Med (2002) 0.75
Electrochemistry: an efficient way to chemically modify individual monolayers of graphene. Small (2012) 0.75
A more reliable measurement method for metal/graphene contact resistance. Nanotechnology (2015) 0.75
Palladium-catalyzed highly efficient synthesis of functionalized indolizines via cross-coupling/cycloisomerization cascade. Chem Commun (Camb) (2015) 0.75
Phase locking of slab laser amplifiers via square wave dithering algorithm. Appl Opt (2014) 0.75
ERRATUM: Establishment of a primed pluripotent epiblast stem cell in FGF4-based conditions. Sci Rep (2015) 0.75
Tunable liquid crystal microlens array using hole patterned electrode structure with ultrathin glass slab. Appl Opt (2012) 0.75
Direct investigation and accurate control of phase profile in liquid-crystal optical-phased array for beam steering. Appl Opt (2013) 0.75
Substrate specificity for the hydroxylation of polyoxygenated 4(20),11-taxadienes by Ginkgo cell suspension cultures. Bioorg Chem (2003) 0.75