Published in Genes Dev on March 15, 2010
Epigenetic changes play critical role in age-associated dysfunctions of the liver. Aging Cell (2010) 1.05
Liver regeneration and aging: a current perspective. Curr Gerontol Geriatr Res (2011) 0.95
Growth and division--not a one-way road. Curr Opin Cell Biol (2010) 0.94
Maternal hepatic growth response to pregnancy in the mouse. Exp Biol Med (Maywood) (2011) 0.83
Nrf2 participates in regulating maternal hepatic adaptations to pregnancy. J Cell Sci (2013) 0.80
The rejuvenating effect of pregnancy on muscle regeneration. Aging Cell (2015) 0.77
Amniotic Epithelial Cells: A New Tool to Combat Aging and Age-Related Diseases? Front Cell Dev Biol (2016) 0.75
Multiparity improves outcomes after cerebral ischemia in female mice despite features of increased metabovascular risk. Proc Natl Acad Sci U S A (2017) 0.75
AKT/PKB signaling: navigating downstream. Cell (2007) 31.26
Liver regeneration. Science (1997) 12.80
Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature (2005) 11.23
Liver regeneration. J Cell Physiol (2007) 6.69
Understanding the odd science of aging. Cell (2005) 6.50
Liver regeneration: from myth to mechanism. Nat Rev Mol Cell Biol (2004) 6.36
Stems cells and the pathways to aging and cancer. Cell (2008) 5.99
Pregnancy-stimulated neurogenesis in the adult female forebrain mediated by prolactin. Science (2003) 3.90
Menin controls growth of pancreatic beta-cells in pregnant mice and promotes gestational diabetes mellitus. Science (2007) 3.55
Age to survive: DNA damage and aging. Trends Genet (2008) 2.05
Aging reduces proliferative capacities of liver by switching pathways of C/EBPalpha growth arrest. Cell (2003) 1.98
Ageing: balancing regeneration and cancer. Nature (2006) 1.88
Operative mortality after hepatic resection: are literature-based rates broadly applicable? J Gastrointest Surg (2008) 1.69
THE INFLUENCE OF AGE UPON THE INCORPORATION OF THYMIDINE-2-C14 INTO THE DNA OF REGENERATING RAT LIVER. Cancer Res (1964) 1.63
White matter plasticity and enhanced remyelination in the maternal CNS. J Neurosci (2007) 1.54
Age-specific CUGBP1-eIF2 complex increases translation of CCAAT/enhancer-binding protein beta in old liver. J Biol Chem (2006) 1.52
Compensatory recovery of liver mass by Akt-mediated hepatocellular hypertrophy in liver-specific STAT3-deficient mice. J Hepatol (2005) 1.31
The survival pathways phosphatidylinositol-3 kinase (PI3-K)/phosphoinositide-dependent protein kinase 1 (PDK1)/Akt modulate liver regeneration through hepatocyte size rather than proliferation. Hepatology (2009) 1.26
Recovery of liver mass without proliferation of hepatocytes after partial hepatectomy in Skp2-deficient mice. Cancer Res (2002) 1.15
Role of caspase-8 in hepatocyte response to infection and injury in mice. Hepatology (2007) 1.15
Akt-mediated liver growth promotes induction of cyclin E through a novel translational mechanism and a p21-mediated cell cycle arrest. J Biol Chem (2007) 1.02
Liver growth in the lactating rat. J Endocrinol (1958) 0.94
Reconstitution of liver mass via cellular hypertrophy in the rat. Hepatology (2001) 0.90
The effect of rapamycin on DNA synthesis in multiple tissues from late gestation fetal and postnatal rats. Am J Physiol Cell Physiol (2008) 0.87
Cell-matrix interactions in aging: role of receptors and matricryptins. Ageing Res Rev (2004) 0.86
Reproduction in mice: liver enlargement in mice during pregnancy and lactation. Life Sci (1987) 0.83
Magnetic resonance imaging provides accurate and precise volume determination of the regenerating mouse liver. J Gastrointest Surg (2004) 0.82
NF-kappaB functions as a tumour promoter in inflammation-associated cancer. Nature (2004) 15.14
Linking DNA methylation and histone modification: patterns and paradigms. Nat Rev Genet (2009) 12.08
Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer. Nat Genet (2006) 10.47
VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells. Cell (2006) 9.32
G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis. Nat Cell Biol (2006) 5.16
Oct-3/4 is a dose-dependent oncogenic fate determinant. Cancer Cell (2003) 4.50
Control of pancreatic β cell regeneration by glucose metabolism. Cell Metab (2011) 3.35
Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis. FASEB J (2004) 2.94
Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy. EMBO J (2002) 2.74
Self-renewal does not predict tumor growth potential in mouse models of high-grade glioma. Cancer Cell (2012) 2.50
Programming of DNA methylation patterns. Annu Rev Biochem (2012) 2.32
Epigenetic ontogeny of the Igk locus during B cell development. Nat Immunol (2004) 2.25
Investigation of the infertile couple: should diagnostic laparoscopy be performed after normal hysterosalpingography in treating infertility suspected to be of unknown origin? Hum Reprod (2002) 2.12
TCR zeta down-regulation under chronic inflammation is mediated by myeloid suppressor cells differentially distributed between various lymphatic organs. J Immunol (2006) 2.05
Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. Mol Cell Biol (2008) 1.96
Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer. Cancer Cell (2013) 1.86
CKIα ablation highlights a critical role for p53 in invasiveness control. Nature (2011) 1.72
Cancer and inflammation: promise for biologic therapy. J Immunother (2010) 1.72
Allelic 'choice' governs somatic hypermutation in vivo at the immunoglobulin kappa-chain locus. Nat Immunol (2007) 1.68
A unique developmental pattern of Oct-3/4 DNA methylation is controlled by a cis-demodification element. J Biol Chem (2002) 1.67
Epithelial microRNAs regulate gut mucosal immunity via epithelium-T cell crosstalk. Nat Immunol (2011) 1.67
Lyn is a target gene for prostate cancer: sequence-based inhibition induces regression of human tumor xenografts. Cancer Res (2004) 1.60
Epigenetics of haematopoietic cell development. Nat Rev Immunol (2011) 1.58
Hyaluronic acid can successfully replace albumin as the sole macromolecule in a human embryo transfer medium. Fertil Steril (2003) 1.54
The expression level of ligands for natural killer cell receptors predicts response to bacillus Calmette-Guerin therapy: a pilot study. J Urol (2007) 1.50
Complications of hysteroscopic surgery: "Beyond the learning curve". J Minim Invasive Gynecol (2007) 1.47
In vitro fertilization-intracytoplasmic sperm injection success rates with cryopreserved sperm from patients with malignant disease. Fertil Steril (2005) 1.46
Preoperative briefing in the operating room: shared cognition, teamwork, and patient safety. Chest (2010) 1.46
Retinal incorporation and differentiation of neural precursors derived from human embryonic stem cells. Stem Cells (2005) 1.45
Cell surface expression and secretion of heparanase markedly promote tumor angiogenesis and metastasis. Proc Natl Acad Sci U S A (2002) 1.45
Resuscitation with aged blood exacerbates liver injury in a hemorrhagic rat model. Crit Care Med (2013) 1.44
The pregnant motor vehicle accident casualty: adherence to basic workup and admission guidelines. Ann Surg (2011) 1.42
Heparanase promotes growth, angiogenesis and survival of primary breast tumors. Int J Cancer (2006) 1.42
Heparanase accelerates wound angiogenesis and wound healing in mouse and rat models. FASEB J (2005) 1.32
Monoallelic gene expression: a repertoire of recurrent themes. Immunol Rev (2004) 1.32
The chemokine CXCL16 and its receptor, CXCR6, as markers and promoters of inflammation-associated cancers. PLoS One (2009) 1.29
S100A8 and S100A9 are novel nuclear factor kappa B target genes during malignant progression of murine and human liver carcinogenesis. Hepatology (2009) 1.28
Mutant KRAS is a druggable target for pancreatic cancer. Proc Natl Acad Sci U S A (2013) 1.26
Accelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks. Proc Natl Acad Sci U S A (2010) 1.26
Function of heparanase in prostate tumorigenesis: potential for therapy. Clin Cancer Res (2008) 1.25
Inflammation and cancer: is the link as simple as we think? J Invest Dermatol (2005) 1.23
A senescence-inflammatory switch from cancer-inhibitory to cancer-promoting mechanism. Cancer Cell (2013) 1.22
Cleavage site selection within a folded substrate by the ATP-dependent lon protease. J Biol Chem (2005) 1.16
Role of caspase-8 in hepatocyte response to infection and injury in mice. Hepatology (2007) 1.15
Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity. J Biol Chem (2004) 1.14
A working group classification of focal prostate atrophy lesions. Am J Surg Pathol (2006) 1.13
Contradictory functions of NF-kappaB in liver physiology and cancer. Cancer Lett (2008) 1.12
Micro-organ ovarian transplantation enables pregnancy: a case report. Hum Reprod (2011) 1.11
Glucose regulates cyclin D2 expression in quiescent and replicating pancreatic β-cells through glycolysis and calcium channels. Endocrinology (2011) 1.11
Thin unresponsive endometrium--a possible complication of surgical curettage compromising ART outcome. J Assist Reprod Genet (2008) 1.08
Choreography of Ig allelic exclusion. Curr Opin Immunol (2008) 1.07
Transcription factor MITF regulates cardiac growth and hypertrophy. J Clin Invest (2006) 1.07
Regulation of the polycomb protein Ring1B by self-ubiquitination or by E6-AP may have implications to the pathogenesis of Angelman syndrome. Proc Natl Acad Sci U S A (2010) 1.07
Repeated implantation failure: clinical approach. Fertil Steril (2012) 1.07
CXCR4 antagonist 4F-benzoyl-TN14003 inhibits leukemia and multiple myeloma tumor growth. Exp Hematol (2010) 1.07
Interaction between CXCR4 and CCL20 pathways regulates tumor growth. PLoS One (2009) 1.07
Toll-like receptor 3 signaling attenuates liver regeneration. Hepatology (2009) 1.06
The haematopoietic specific signal transducer Vav1 is expressed in a subset of human neuroblastomas. J Pathol (2003) 1.06
Oct-3/4 regulates stem cell identity and cell fate decisions by modulating Wnt/β-catenin signalling. EMBO J (2010) 1.05
A common pathway mediated through Toll-like receptors leads to T- and natural killer-cell immunosuppression. Blood (2007) 1.04
Allelic inactivation of rDNA loci. Genes Dev (2009) 1.04
At what age can human oocytes be obtained? Fertil Steril (2008) 1.03
Derivation of xeno-free and GMP-grade human embryonic stem cells--platforms for future clinical applications. PLoS One (2012) 1.03
The haematopoietic specific signal transducer Vav1 is aberrantly expressed in lung cancer and plays a role in tumourigenesis. J Pathol (2009) 1.03
Assessment and treatment of repeated implantation failure (RIF). J Assist Reprod Genet (2012) 1.00
beta-TrCP inhibition reduces prostate cancer cell growth via upregulation of the aryl hydrocarbon receptor. PLoS One (2010) 0.99
Receptor for advanced glycation endproducts (RAGE) is a key regulator of oval cell activation and inflammation-associated liver carcinogenesis in mice. Hepatology (2013) 0.99
Biallelic germline transcription at the kappa immunoglobulin locus. J Exp Med (2003) 0.98
Functional MR imaging during hypercapnia and hyperoxia: noninvasive tool for monitoring changes in liver perfusion and hemodynamics in a rat model. Radiology (2007) 0.94
Neutrophils recruit regulatory T-cells into tumors via secretion of CCL17--a new mechanism of impaired antitumor immunity. Int J Cancer (2014) 0.94
Tamoxifen induces heparanase expression in estrogen receptor-positive breast cancer. Clin Cancer Res (2007) 0.92
The AP-1 repressor protein, JDP2, potentiates hepatocellular carcinoma in mice. Mol Cancer (2010) 0.92
Role of androgens in the treatment of patients with low ovarian response. Reprod Biomed Online (2009) 0.92
Splicing factor hnRNP A2 activates the Ras-MAPK-ERK pathway by controlling A-Raf splicing in hepatocellular carcinoma development. RNA (2014) 0.92
Perinatal outcome of pregnancies complicated by placenta accreta. Obstet Gynecol (2004) 0.91
Vascular profile characterization of liver tumors by magnetic resonance imaging using hemodynamic response imaging in mice. Neoplasia (2011) 0.91
Herpes simplex virus type 1 preferentially targets human colon carcinoma: role of extracellular matrix. J Virol (2007) 0.91
Oocyte collection during cryopreservation of the ovarian cortex. Fertil Steril (2003) 0.90
Clonal allelic predetermination of immunoglobulin-κ rearrangement. Nature (2012) 0.89
A Key role for cyclic AMP-responsive element binding protein in hypoxia-mediated activation of the angiogenesis factor CCN1 (CYR61) in Tumor cells. Mol Cancer Res (2008) 0.88
Differential accessibility at the kappa chain locus plays a role in allelic exclusion. EMBO J (2002) 0.87
Ovarian hyperstimulation syndrome: definition, incidence, and classification. Semin Reprod Med (2010) 0.87
Spermatogenesis rescue in a mouse deficient for the ubiquitin ligase SCF{beta}-TrCP by single substrate depletion. Genes Dev (2010) 0.87
A trimerizing GxxxG motif is uniquely inserted in the severe acute respiratory syndrome (SARS) coronavirus spike protein transmembrane domain. Biochemistry (2006) 0.87
Expression of the RNA-binding protein VICKZ in normal hematopoietic tissues and neoplasms. Haematologica (2007) 0.86
An Ashkenazi founder mutation in the MSH6 gene leading to HNPCC. Fam Cancer (2010) 0.86
Etk/Bmx regulates proteinase-activated-receptor1 (PAR1) in breast cancer invasion: signaling partners, hierarchy and physiological significance. PLoS One (2010) 0.86
Inflammation-induced hepatocellular carcinoma is dependent on CCR5 in mice. Hepatology (2013) 0.85
Should ovarian cryopreservation be offered to girls with cancer. Pediatr Blood Cancer (2007) 0.85
Functional magnetic resonance imaging monitoring of pathological changes in rodent livers during hyperoxia and hypercapnia. Hepatology (2008) 0.85
Hemodynamic response imaging: a potential tool for the assessment of angiogenesis in brain tumors. PLoS One (2012) 0.85
α-Synuclein expression selectively affects tumorigenesis in mice modeling Parkinson's disease. PLoS One (2011) 0.84
Hemodynamic response magnetic resonance imaging: application for renal hemodynamic characterization. Nephrol Dial Transplant (2013) 0.84
Homozygosity of MSH2 c.1906G-->C germline mutation is associated with childhood colon cancer, astrocytoma and signs of Neurofibromatosis type I. Fam Cancer (2008) 0.84