Published in Am J Psychiatry on March 15, 2010
Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor. Nature (2011) 4.94
Pain symptomatology and pain medication use in civilian PTSD. Pain (2011) 2.16
Neurogenesis and generalization: a new approach to stratify and treat anxiety disorders. Nat Neurosci (2012) 2.15
Fear conditioning, synaptic plasticity and the amygdala: implications for posttraumatic stress disorder. Trends Neurosci (2011) 2.12
Estrogen levels are associated with extinction deficits in women with posttraumatic stress disorder. Biol Psychiatry (2012) 2.02
Seeking a spotless mind: extinction, deconsolidation, and erasure of fear memory. Neuron (2011) 1.80
Implications of memory modulation for post-traumatic stress and fear disorders. Nat Neurosci (2013) 1.72
Impaired safety signal learning may be a biomarker of PTSD. Neuropharmacology (2011) 1.52
Putative biological mechanisms for the association between early life adversity and the subsequent development of PTSD. Psychopharmacology (Berl) (2010) 1.49
Developmental perspectives on personality: implications for ecological and evolutionary studies of individual differences. Philos Trans R Soc Lond B Biol Sci (2010) 1.47
Functional anatomy of ventromedial prefrontal cortex: implications for mood and anxiety disorders. Mol Psychiatry (2011) 1.47
The fragrant power of collective fear. PLoS One (2015) 1.39
Fear conditioning and early life vulnerabilities: two distinct pathways of emotional dysregulation and brain dysfunction in PTSD. Eur J Psychotraumatol (2010) 1.38
PTSD and gene variants: new pathways and new thinking. Neuropharmacology (2011) 1.34
Amygdala volume changes in posttraumatic stress disorder in a large case-controlled veterans group. Arch Gen Psychiatry (2012) 1.27
Altered resting-state functional connectivity of basolateral and centromedial amygdala complexes in posttraumatic stress disorder. Neuropsychopharmacology (2013) 1.26
Dark-enhanced startle responses and heart rate variability in a traumatized civilian sample: putative sex-specific correlates of posttraumatic stress disorder. Psychosom Med (2012) 1.20
From Pavlov to PTSD: the extinction of conditioned fear in rodents, humans, and anxiety disorders. Neurobiol Learn Mem (2013) 1.19
Estrogen and extinction of fear memories: implications for posttraumatic stress disorder treatment. Biol Psychiatry (2015) 1.17
White matter integrity in highly traumatized adults with and without post-traumatic stress disorder. Neuropsychopharmacology (2012) 1.14
Cannabinoid facilitation of fear extinction memory recall in humans. Neuropharmacology (2012) 1.14
Reversible gating of endocannabinoid plasticity in the amygdala by chronic stress: a potential role for monoacylglycerol lipase inhibition in the prevention of stress-induced behavioral adaptation. Neuropsychopharmacology (2011) 1.11
Understanding the mental health effects of indirect exposure to mass trauma through the media. JAMA (2011) 1.06
Tailoring therapeutic strategies for treating posttraumatic stress disorder symptom clusters. Neuropsychiatr Dis Treat (2010) 1.06
PACAP receptor gene polymorphism impacts fear responses in the amygdala and hippocampus. Proc Natl Acad Sci U S A (2014) 1.02
BDNF function as a potential mediator of bipolar disorder and post-traumatic stress disorder comorbidity. Mol Psychiatry (2011) 1.02
Orexin/hypocretin system modulates amygdala-dependent threat learning through the locus coeruleus. Proc Natl Acad Sci U S A (2013) 1.01
Synergistic activation of dopamine D1 and TrkB receptors mediate gain control of synaptic plasticity in the basolateral amygdala. PLoS One (2011) 1.01
Adult Hippocampal Neurogenesis, Fear Generalization, and Stress. Neuropsychopharmacology (2015) 1.01
Neuropeptide regulation of fear and anxiety: Implications of cholecystokinin, endogenous opioids, and neuropeptide Y. Physiol Behav (2012) 0.98
Differential Genetic and Epigenetic Regulation of catechol-O-methyltransferase is Associated with Impaired Fear Inhibition in Posttraumatic Stress Disorder. Front Behav Neurosci (2013) 0.98
Considering PTSD from the perspective of brain processes: a psychological construction approach. J Trauma Stress (2011) 0.96
A model of amygdala-hippocampal-prefrontal interaction in fear conditioning and extinction in animals. Brain Cogn (2012) 0.96
Serotonin transporter gene polymorphisms and brain function during emotional distraction from cognitive processing in posttraumatic stress disorder. BMC Psychiatry (2011) 0.95
An fMRI study of the brain responses of traumatized mothers to viewing their toddlers during separation and play. Soc Cogn Affect Neurosci (2011) 0.95
Inhibition of fear is differentially associated with cycling estrogen levels in women. J Psychiatry Neurosci (2013) 0.93
Genome-wide association for fear conditioning in an advanced intercross mouse line. Behav Genet (2012) 0.93
Learning models of PTSD: Theoretical accounts and psychobiological evidence. Int J Psychophysiol (2014) 0.92
Conditioned fear associated phenotypes as robust, translational indices of trauma-, stressor-, and anxiety-related behaviors. Front Psychiatry (2014) 0.91
Neuropsychological and neuroimaging findings in traumatic brain injury and post-traumatic stress disorder. Dialogues Clin Neurosci (2011) 0.91
Enhanced fear expression in a psychopathological mouse model of trait anxiety: pharmacological interventions. PLoS One (2011) 0.91
Impact of predatory threat on fear extinction in Lewis rats. Learn Mem (2010) 0.90
An open-label study of guanfacine extended release for traumatic stress related symptoms in children and adolescents. J Child Adolesc Psychopharmacol (2013) 0.90
Effects of sleep on memory for conditioned fear and fear extinction. Psychol Bull (2015) 0.90
Angiotensin type 1 receptor inhibition enhances the extinction of fear memory. Biol Psychiatry (2013) 0.89
The stressor criterion for posttraumatic stress disorder: does it matter? J Clin Psychiatry (2012) 0.88
Diagnostic Biomarkers for Posttraumatic Stress Disorder: Promising Horizons from Translational Neuroscience Research. Biol Psychiatry (2015) 0.88
Correcting systematic inflation in genetic association tests that consider interaction effects: application to a genome-wide association study of posttraumatic stress disorder. JAMA Psychiatry (2014) 0.88
Complex PTSD, affect dysregulation, and borderline personality disorder. Borderline Personal Disord Emot Dysregul (2014) 0.87
The Dissociative Subtype of Posttraumatic Stress Disorder: Unique Resting-State Functional Connectivity of Basolateral and Centromedial Amygdala Complexes. Neuropsychopharmacology (2015) 0.87
Recent progress in understanding the pathophysiology of post-traumatic stress disorder: implications for targeted pharmacological treatment. CNS Drugs (2013) 0.87
Hippocampal-prefrontal circuit and disrupted functional connectivity in psychiatric and neurodegenerative disorders. Biomed Res Int (2015) 0.87
Intranasal Oxytocin Normalizes Amygdala Functional Connectivity in Posttraumatic Stress Disorder. Neuropsychopharmacology (2016) 0.87
Posttraumatic stress disorder in anorexia nervosa. Psychosom Med (2011) 0.86
Animal models of fear relapse. ILAR J (2014) 0.85
Comparison of the activation of somatostatin- and neuropeptide Y-containing neuronal populations of the rat amygdala following two different anxiogenic stressors. Exp Neurol (2012) 0.85
High-resolution genetic mapping of complex traits from a combined analysis of F2 and advanced intercross mice. Genetics (2014) 0.85
Habenula volume in post-traumatic stress disorder measured with high-resolution MRI. Biol Mood Anxiety Disord (2011) 0.85
Neuroimaging resilience to stress: a review. Front Behav Neurosci (2013) 0.84
The role of serotonin 5-HT2A receptors in memory and cognition. Front Pharmacol (2015) 0.84
Targeting memory processes with drugs to prevent or cure PTSD. Expert Opin Investig Drugs (2012) 0.84
Resilient emotionality and molecular compensation in mice lacking the oligodendrocyte-specific gene Cnp1. Transl Psychiatry (2011) 0.84
Neural correlates of individual differences in fear learning. Behav Brain Res (2015) 0.83
Context Processing and the Neurobiology of Post-Traumatic Stress Disorder. Neuron (2016) 0.83
Pam heterozygous mice reveal essential role for Cu in amygdalar behavioral and synaptic function. Ann N Y Acad Sci (2014) 0.83
Distinct effects of repeated restraint stress on basolateral amygdala neuronal membrane properties in resilient adolescent and adult rats. Neuropsychopharmacology (2014) 0.83
The impact of cultural differences in self-representation on the neural substrates of posttraumatic stress disorder. Eur J Psychotraumatol (2016) 0.83
Autonomic and inflammatory consequences of posttraumatic stress disorder and the link to cardiovascular disease. Am J Physiol Regul Integr Comp Physiol (2015) 0.83
Neural systems for cognitive and emotional processing in posttraumatic stress disorder. Front Psychol (2012) 0.82
Common Polymorphisms in the Age of Research Domain Criteria (RDoC): Integration and Translation. Biol Psychiatry (2015) 0.82
Effects of stress on AMPA receptor distribution and function in the basolateral amygdala. Brain Struct Funct (2013) 0.82
The role of FKBP5 genotype in moderating long-term effectiveness of exposure-based psychotherapy for posttraumatic stress disorder. Transl Psychiatry (2014) 0.81
Bidirectional regulation of synaptic plasticity in the basolateral amygdala induced by the D1-like family of dopamine receptors and group II metabotropic glutamate receptors. J Physiol (2014) 0.81
Neural substrates underlying learning-related changes of the unconditioned fear response. Open Neuroimag J (2013) 0.81
Stress-induced sensitization of cortical adrenergic receptors following a history of cannabinoid exposure. Exp Neurol (2012) 0.81
Maltreatment Exposure, Brain Structure, and Fear Conditioning in Children and Adolescents. Neuropsychopharmacology (2015) 0.81
Cannabinoid modulation of chronic mild stress-induced selective enhancement of trace fear conditioning in adolescent rats. J Psychopharmacol (2013) 0.81
Neurobiological indicators of disinhibition in posttraumatic stress disorder. Hum Brain Mapp (2015) 0.79
Falling out of time: enhanced memory for scenes presented at behaviorally irrelevant points in time in posttraumatic stress disorder (PTSD). PLoS One (2012) 0.78
Controllability modulates the neural response to predictable but not unpredictable threat in humans. Neuroimage (2015) 0.78
Translational neuroscience measures of fear conditioning across development: applications to high-risk children and adolescents. Biol Mood Anxiety Disord (2013) 0.78
Drug discovery strategies that focus on the endocannabinoid signaling system in psychiatric disease. Expert Opin Drug Discov (2014) 0.78
Toward a translational approach to targeting the endocannabinoid system in posttraumatic stress disorder: a critical review of preclinical research. Biol Psychol (2014) 0.78
BDNF-dependent consolidation of fear memories in the perirhinal cortex. Front Behav Neurosci (2013) 0.78
Neural and genetic markers of vulnerability to post-traumatic stress symptoms among survivors of the World Trade Center attacks. Soc Cogn Affect Neurosci (2014) 0.78
Psychophysiology and posttraumatic stress disorder symptom profile in pregnant African-American women with trauma exposure. Arch Womens Ment Health (2014) 0.77
Out with the old and in with the new: Synaptic mechanisms of extinction in the amygdala. Brain Res (2014) 0.77
Identifying profiles of recovery from reward devaluation in rats. Behav Brain Res (2014) 0.77
ApoE2 Exaggerates PTSD-Related Behavioral, Cognitive, and Neuroendocrine Alterations. Neuropsychopharmacology (2015) 0.77
Adolescent Social Isolation as a Model of Heightened Vulnerability to Comorbid Alcoholism and Anxiety Disorders. Alcohol Clin Exp Res (2016) 0.76
The role of stress and fear in the development of mental disorders. Psychiatr Clin North Am (2014) 0.76
Graded fear generalization enhances the level of cfos-positive neurons specifically in the basolateral amygdala. J Neurosci Res (2016) 0.76
CHILDHOOD MALTREATMENT PREDICTS REDUCED INHIBITION-RELATED ACTIVITY IN THE ROSTRAL ANTERIOR CINGULATE IN PTSD, BUT NOT TRAUMA-EXPOSED CONTROLS. Depress Anxiety (2016) 0.76
Disruption of white matter structural integrity and connectivity in posttraumatic stress disorder: A TBSS and tractography study. Depress Anxiety (2017) 0.75
PTSD and cognitive symptoms relate to inhibition-related prefrontal activation and functional connectivity. Depress Anxiety (2017) 0.75
Treatment of Post-Traumatic Stress Disorders with the Alpha-1 Adrenergic Antagonist Prazosin. Can J Psychiatry (2016) 0.75
Accessible Neurobehavioral Anger-Related Markers for Vulnerability to Post-Traumatic Stress Symptoms in a Population of Male Soldiers. Front Behav Neurosci (2017) 0.75
Parent-child relationship quality and family transmission of parent posttraumatic stress disorder symptoms and child externalizing and internalizing symptoms following fathers' exposure to combat trauma. Dev Psychopathol (2016) 0.75
Interpersonal violence in posttraumatic women: brain networks triggered by trauma-related pictures. Soc Cogn Affect Neurosci (2016) 0.75
Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry (2005) 58.92
Posttraumatic stress disorder in the National Comorbidity Survey. Arch Gen Psychiatry (1995) 30.84
Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science (2003) 28.61
Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval. Nature (2000) 10.16
Functional neuroanatomy of emotion: a meta-analysis of emotion activation studies in PET and fMRI. Neuroimage (2002) 9.66
Extinction learning in humans: role of the amygdala and vmPFC. Neuron (2004) 8.63
Neurons in medial prefrontal cortex signal memory for fear extinction. Nature (2002) 8.43
Emotional processing of fear: exposure to corrective information. Psychol Bull (1986) 8.03
The endogenous cannabinoid system controls extinction of aversive memories. Nature (2002) 7.19
Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults. JAMA (2008) 6.60
Preventing the return of fear in humans using reconsolidation update mechanisms. Nature (2009) 5.82
Recall of fear extinction in humans activates the ventromedial prefrontal cortex and hippocampus in concert. Biol Psychiatry (2007) 5.56
Human amygdala activation during conditioned fear acquisition and extinction: a mixed-trial fMRI study. Neuron (1998) 5.54
Cognitive enhancers as adjuncts to psychotherapy: use of D-cycloserine in phobic individuals to facilitate extinction of fear. Arch Gen Psychiatry (2004) 5.26
Switching on and off fear by distinct neuronal circuits. Nature (2008) 5.22
A multidimensional meta-analysis of psychotherapy for PTSD. Am J Psychiatry (2005) 5.05
Neurobiological basis of failure to recall extinction memory in posttraumatic stress disorder. Biol Psychiatry (2009) 4.84
Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene. Arch Gen Psychiatry (2008) 4.65
Extinction-reconsolidation boundaries: key to persistent attenuation of fear memories. Science (2009) 4.63
Facilitation of conditioned fear extinction by systemic administration or intra-amygdala infusions of D-cycloserine as assessed with fear-potentiated startle in rats. J Neurosci (2002) 4.52
Different projections of the central amygdaloid nucleus mediate autonomic and behavioral correlates of conditioned fear. J Neurosci (1988) 4.47
New vistas on amygdala networks in conditioned fear. J Neurophysiol (2004) 4.44
Psychobiological mechanisms of resilience and vulnerability: implications for successful adaptation to extreme stress. Am J Psychiatry (2004) 4.32
Exaggerated amygdala response to masked facial stimuli in posttraumatic stress disorder: a functional MRI study. Biol Psychiatry (2000) 4.30
Amygdala inhibitory circuits and the control of fear memory. Neuron (2009) 4.16
A functional magnetic resonance imaging study of amygdala and medial prefrontal cortex responses to overtly presented fearful faces in posttraumatic stress disorder. Arch Gen Psychiatry (2005) 4.07
A comparison of cognitive-processing therapy with prolonged exposure and a waiting condition for the treatment of chronic posttraumatic stress disorder in female rape victims. J Consult Clin Psychol (2002) 3.85
Classical fear conditioning in the anxiety disorders: a meta-analysis. Behav Res Ther (2005) 3.83
Activation of the left amygdala to a cognitive representation of fear. Nat Neurosci (2001) 3.71
Extinction of emotional learning: contribution of medial prefrontal cortex. Neurosci Lett (1993) 3.69
Long story short: the serotonin transporter in emotion regulation and social cognition. Nat Neurosci (2007) 3.66
Augmentation of behavior therapy with D-cycloserine for obsessive-compulsive disorder. Am J Psychiatry (2008) 3.63
Why we think plasticity underlying Pavlovian fear conditioning occurs in the basolateral amygdala. Neuron (1999) 3.62
Extinction circuits for fear and addiction overlap in prefrontal cortex. Learn Mem (2009) 3.62
A twin study of genetic and environmental contributions to liability for posttraumatic stress symptoms. Arch Gen Psychiatry (1993) 3.60
Microstimulation reveals opposing influences of prelimbic and infralimbic cortex on the expression of conditioned fear. Learn Mem (2006) 3.52
Treatment of posttraumatic stress disorder in rape victims: a comparison between cognitive-behavioral procedures and counseling. J Consult Clin Psychol (1991) 3.45
Extinction of fear-potentiated startle: blockade by infusion of an NMDA antagonist into the amygdala. J Neurosci (1992) 3.40
Amygdala intercalated neurons are required for expression of fear extinction. Nature (2008) 3.37
Beyond extinction: erasing human fear responses and preventing the return of fear. Nat Neurosci (2009) 3.32
Different mechanisms of fear extinction dependent on length of time since fear acquisition. Learn Mem (2006) 3.30
Neural circuitry underlying the regulation of conditioned fear and its relation to extinction. Neuron (2008) 3.23
The emotional counting Stroop paradigm: a functional magnetic resonance imaging probe of the anterior cingulate affective division. Biol Psychiatry (1998) 3.20
A functional MRI study of human amygdala responses to facial expressions of fear versus anger. Emotion (2001) 3.15
Pilot study of secondary prevention of posttraumatic stress disorder with propranolol. Biol Psychiatry (2002) 3.15
A comparison of exposure therapy, stress inoculation training, and their combination for reducing posttraumatic stress disorder in female assault victims. J Consult Clin Psychol (1999) 3.08
Applying learning principles to the treatment of post-trauma reactions. Ann N Y Acad Sci (2003) 3.05
De novo conditioning in trauma-exposed individuals with and without posttraumatic stress disorder. J Abnorm Psychol (2000) 3.03
D-cycloserine augmented exposure therapy for obsessive-compulsive disorder. Biol Psychiatry (2007) 3.03
The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders. Psychoneuroendocrinology (2009) 3.01
Peripheral blood mononuclear cell gene expression profiles identify emergent post-traumatic stress disorder among trauma survivors. Mol Psychiatry (2005) 2.89
Hippocampus-specific deletion of BDNF in adult mice impairs spatial memory and extinction of aversive memories. Mol Psychiatry (2007) 2.84
Genetic and environmental influences on trauma exposure and posttraumatic stress disorder symptoms: a twin study. Am J Psychiatry (2002) 2.82
The serotonin transporter genotype and social support and moderation of posttraumatic stress disorder and depression in hurricane-exposed adults. Am J Psychiatry (2007) 2.81
Neural organization of the defensive behavior system responsible for fear. Psychon Bull Rev (1994) 2.79
Thickness of ventromedial prefrontal cortex in humans is correlated with extinction memory. Proc Natl Acad Sci U S A (2005) 2.78
Presence and acquired origin of reduced recall for fear extinction in PTSD: results of a twin study. J Psychiatr Res (2008) 2.78
A role for the human dorsal anterior cingulate cortex in fear expression. Biol Psychiatry (2007) 2.78
Augmentation of exposure therapy with D-cycloserine for social anxiety disorder. Arch Gen Psychiatry (2006) 2.77
Brain-derived neurotrophic factor and tyrosine kinase receptor B involvement in amygdala-dependent fear conditioning. J Neurosci (2004) 2.73
A primary acoustic startle circuit: lesion and stimulation studies. J Neurosci (1982) 2.73
From fear to safety and back: reversal of fear in the human brain. J Neurosci (2008) 2.63
Neural correlates of exposure to traumatic pictures and sound in Vietnam combat veterans with and without posttraumatic stress disorder: a positron emission tomography study. Biol Psychiatry (1999) 2.62
Fear and anxiety: animal models and human cognitive psychophysiology. J Affect Disord (2000) 2.58
The functional neuroanatomy of PTSD: a critical review. Prog Brain Res (2008) 2.56
Fear-potentiated startle: a neural and pharmacological analysis. Behav Brain Res (1993) 2.43
Effects of D-cycloserine on extinction of conditioned freezing. Behav Neurosci (2003) 2.39
Prefrontal control of the amygdala. J Neurosci (2005) 2.39
Brain activation in PTSD in response to trauma-related stimuli. Biol Psychiatry (1999) 2.38
Regional cerebral blood flow during script-driven imagery in childhood sexual abuse-related PTSD: A PET investigation. Am J Psychiatry (1999) 2.35
Fear-potentiated startle conditioning to explicit and contextual cues in Gulf War veterans with posttraumatic stress disorder. J Abnorm Psychol (1999) 2.34
Impaired fear inhibition is a biomarker of PTSD but not depression. Depress Anxiety (2010) 2.27
A symptom provocation study of posttraumatic stress disorder using positron emission tomography and script-driven imagery. Arch Gen Psychiatry (1996) 2.22
Models and mechanisms of anxiety: evidence from startle studies. Psychopharmacology (Berl) (2007) 2.18
A meta-analysis of D-cycloserine and the facilitation of fear extinction and exposure therapy. Biol Psychiatry (2008) 2.17
Amygdala BDNF signaling is required for consolidation but not encoding of extinction. Nat Neurosci (2006) 2.10
Regulation of synaptic plasticity genes during consolidation of fear conditioning. J Neurosci (2002) 2.10
The neuropsychopharmacology of action inhibition: cross-species translation of the stop-signal and go/no-go tasks. Psychopharmacology (Berl) (2008) 2.07
Consolidation of extinction learning involves transfer from NMDA-independent to NMDA-dependent memory. J Neurosci (2001) 2.05
A randomized controlled trial of D-cycloserine enhancement of exposure therapy for social anxiety disorder. Biol Psychiatry (2008) 2.03
Psychophysiologic assessment of aversive conditioning in posttraumatic stress disorder. Biol Psychiatry (2000) 2.00
Positron emission tomographic imaging of neural correlates of a fear acquisition and extinction paradigm in women with childhood sexual-abuse-related post-traumatic stress disorder. Psychol Med (2005) 1.99
Psychophysiologic assessment of posttraumatic stress disorder imagery in Vietnam combat veterans. Arch Gen Psychiatry (1987) 1.97
The relevance of recent developments in classical conditioning to understanding the etiology and maintenance of anxiety disorders. Acta Psychol (Amst) (2008) 1.95
Polymorphisms in FKBP5 are associated with peritraumatic dissociation in medically injured children. Mol Psychiatry (2005) 1.91
Enhancing cannabinoid neurotransmission augments the extinction of conditioned fear. Neuropsychopharmacology (2005) 1.89
Treatment of posttraumatic stress disorder by exposure and/or cognitive restructuring: a controlled study. Arch Gen Psychiatry (1998) 1.86
Neural correlates of the classic color and emotional stroop in women with abuse-related posttraumatic stress disorder. Biol Psychiatry (2004) 1.85
The Multi-Source Interference Task: an fMRI task that reliably activates the cingulo-frontal-parietal cognitive/attention network. Nat Protoc (2006) 1.85
Gene expression patterns associated with posttraumatic stress disorder following exposure to the World Trade Center attacks. Biol Psychiatry (2009) 1.85
Amygdalar NMDA receptors are critical for new fear learning in previously fear-conditioned rats. J Neurosci (1998) 1.82
Inhibition of the amygdala: key to pathological states? Ann N Y Acad Sci (2003) 1.78
Conditioned fear extinction and reinstatement in a human fear-potentiated startle paradigm. Learn Mem (2006) 1.78
Genetic gating of human fear learning and extinction: possible implications for gene-environment interaction in anxiety disorder. Psychol Sci (2009) 1.76
Posttraumatic stress disorder may be associated with impaired fear inhibition: relation to symptom severity. Psychiatry Res (2009) 1.76
D-cycloserine and the facilitation of extinction of conditioned fear: consequences for reinstatement. Behav Neurosci (2004) 1.75
The role of the human amygdala in the production of conditioned fear responses. Neuroimage (2005) 1.73
Impaired discriminative fear-conditioning resulting from elevated fear responding to learned safety cues among individuals with panic disorder. Behav Res Ther (2008) 1.73
Regulation of gephyrin and GABAA receptor binding within the amygdala after fear acquisition and extinction. J Neurosci (2005) 1.72
Physiologic responses to sudden, loud tones in monozygotic twins discordant for combat exposure: association with posttraumatic stress disorder. Arch Gen Psychiatry (2003) 1.70
Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults. JAMA (2008) 6.60
Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions. Nat Neurosci (2012) 4.71
Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene. Arch Gen Psychiatry (2008) 4.65
Facilitation of conditioned fear extinction by systemic administration or intra-amygdala infusions of D-cycloserine as assessed with fear-potentiated startle in rats. J Neurosci (2002) 4.52
A randomized, double-blind evaluation of D-cycloserine or alprazolam combined with virtual reality exposure therapy for posttraumatic stress disorder in Iraq and Afghanistan War veterans. Am J Psychiatry (2014) 4.25
Trauma exposure and stress-related disorders in inner city primary care patients. Gen Hosp Psychiatry (2009) 3.88
Different mechanisms of fear extinction dependent on length of time since fear acquisition. Learn Mem (2006) 3.30
Brain-derived neurotrophic factor and tyrosine kinase receptor B involvement in amygdala-dependent fear conditioning. J Neurosci (2004) 2.73
Impaired fear inhibition is a biomarker of PTSD but not depression. Depress Anxiety (2010) 2.27
Effect of 7,8-dihydroxyflavone, a small-molecule TrkB agonist, on emotional learning. Am J Psychiatry (2010) 2.25
Pain symptomatology and pain medication use in civilian PTSD. Pain (2011) 2.16
Posttraumatic stress disorder among African Americans in an inner city mental health clinic. Psychiatr Serv (2005) 2.13
Fear conditioning, synaptic plasticity and the amygdala: implications for posttraumatic stress disorder. Trends Neurosci (2011) 2.12
Amygdala BDNF signaling is required for consolidation but not encoding of extinction. Nat Neurosci (2006) 2.10
Using polymorphisms in FKBP5 to define biologically distinct subtypes of posttraumatic stress disorder: evidence from endocrine and gene expression studies. Arch Gen Psychiatry (2011) 2.09
The neuronal transporter gene SLC6A15 confers risk to major depression. Neuron (2011) 2.02
Estrogen levels are associated with extinction deficits in women with posttraumatic stress disorder. Biol Psychiatry (2012) 2.02
Fear extinction in traumatized civilians with posttraumatic stress disorder: relation to symptom severity. Biol Psychiatry (2010) 2.02
Enhancing cannabinoid neurotransmission augments the extinction of conditioned fear. Neuropsychopharmacology (2005) 1.89
Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder. Proc Natl Acad Sci U S A (2013) 1.86
Differential immune system DNA methylation and cytokine regulation in post-traumatic stress disorder. Am J Med Genet B Neuropsychiatr Genet (2011) 1.83
Risk and resilience: genetic and environmental influences on development of the stress response. Depress Anxiety (2009) 1.79
Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD. Sci Transl Med (2013) 1.74
Prelimbic cortical BDNF is required for memory of learned fear but not extinction or innate fear. Proc Natl Acad Sci U S A (2010) 1.72
Implications of memory modulation for post-traumatic stress and fear disorders. Nat Neurosci (2013) 1.72
Regulation of gephyrin and GABAA receptor binding within the amygdala after fear acquisition and extinction. J Neurosci (2005) 1.72
Association of CRP genetic variation and CRP level with elevated PTSD symptoms and physiological responses in a civilian population with high levels of trauma. Am J Psychiatry (2014) 1.60
The renin-angiotensin pathway in posttraumatic stress disorder: angiotensin-converting enzyme inhibitors and angiotensin receptor blockers are associated with fewer traumatic stress symptoms. J Clin Psychiatry (2012) 1.54
Differential regulation of brain-derived neurotrophic factor transcripts during the consolidation of fear learning. Learn Mem (2004) 1.53
Training-induced changes in the expression of GABAA-associated genes in the amygdala after the acquisition and extinction of Pavlovian fear. Eur J Neurosci (2007) 1.43
Epigenomic association analysis identifies smoking-related DNA methylation sites in African Americans. Hum Genet (2013) 1.43
Effect of Childhood Trauma on Adult Depression and Neuroendocrine Function: Sex-Specific Moderation by CRH Receptor 1 Gene. Front Behav Neurosci (2009) 1.41
Beta-catenin is required for memory consolidation. Nat Neurosci (2008) 1.40
DSM-5 and RDoC: progress in psychiatry research? Nat Rev Neurosci (2013) 1.38
Early interventions for PTSD: a review. Depress Anxiety (2012) 1.37
Early intervention may prevent the development of posttraumatic stress disorder: a randomized pilot civilian study with modified prolonged exposure. Biol Psychiatry (2012) 1.37
PTSD and gene variants: new pathways and new thinking. Neuropharmacology (2011) 1.34
Methylation quantitative trait loci (meQTLs) are consistently detected across ancestry, developmental stage, and tissue type. BMC Genomics (2014) 1.34
Learning-dependent structural plasticity in the adult olfactory pathway. J Neurosci (2008) 1.34
Pain medication use among patients with posttraumatic stress disorder. Psychosomatics (2006) 1.32
Brain-derived neurotrophic factor in amygdala-dependent learning. Neuroscientist (2005) 1.31
RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory. Proc Natl Acad Sci U S A (2010) 1.31
Treatment barriers for low-income, urban African Americans with undiagnosed posttraumatic stress disorder. J Trauma Stress (2008) 1.29
Emotion dysregulation and negative affect: association with psychiatric symptoms. J Clin Psychiatry (2011) 1.27
Accounting for population stratification in DNA methylation studies. Genet Epidemiol (2014) 1.25
Emotional learning and glutamate: translational perspectives. CNS Spectr (2005) 1.23
Dark-enhanced startle responses and heart rate variability in a traumatized civilian sample: putative sex-specific correlates of posttraumatic stress disorder. Psychosom Med (2012) 1.20
Moderating effects of resilience on depression in individuals with a history of childhood abuse or trauma exposure. J Affect Disord (2010) 1.20
Pharmacological treatments that facilitate extinction of fear: relevance to psychotherapy. NeuroRx (2006) 1.20
Neural correlates of attention bias to threat in post-traumatic stress disorder. Biol Psychol (2012) 1.17
Substance use, childhood traumatic experience, and Posttraumatic Stress Disorder in an urban civilian population. Depress Anxiety (2010) 1.16
White matter integrity in highly traumatized adults with and without post-traumatic stress disorder. Neuropsychopharmacology (2012) 1.14
Disrupted amygdala-prefrontal functional connectivity in civilian women with posttraumatic stress disorder. J Psychiatr Res (2013) 1.14
Olfactory receptor surface expression is driven by association with the beta2-adrenergic receptor. Proc Natl Acad Sci U S A (2004) 1.14
Tools for translational neuroscience: PTSD is associated with heightened fear responses using acoustic startle but not skin conductance measures. Depress Anxiety (2011) 1.14
The role of neuropeptide Y in the expression and extinction of fear-potentiated startle. J Neurosci (2008) 1.14
Lesions of the habenula produce stress- and dopamine-dependent alterations in prepulse inhibition and locomotion. Brain Res (2006) 1.13
Epigenetic modulation of Homer1a transcription regulation in amygdala and hippocampus with pavlovian fear conditioning. J Neurosci (2012) 1.12
Childhood abuse is associated with increased startle reactivity in adulthood. Depress Anxiety (2009) 1.11
FKBP5 and attention bias for threat: associations with hippocampal function and shape. JAMA Psychiatry (2013) 1.11
Reduced neural activation during an inhibition task is associated with impaired fear inhibition in a traumatized civilian sample. Cortex (2012) 1.11
Chronic overexpression of corticotropin-releasing factor from the central amygdala produces HPA axis hyperactivity and behavioral anxiety associated with gene-expression changes in the hippocampus and paraventricular nucleus of the hypothalamus. Psychoneuroendocrinology (2011) 1.09
DNA extracted from saliva for methylation studies of psychiatric traits: evidence tissue specificity and relatedness to brain. Am J Med Genet B Neuropsychiatr Genet (2014) 1.07
Posttraumatic stress disorder is a risk factor for metabolic syndrome in an impoverished urban population. Gen Hosp Psychiatry (2011) 1.06
ADCYAP1R1 genotype associates with post-traumatic stress symptoms in highly traumatized African-American females. Am J Med Genet B Neuropsychiatr Genet (2013) 1.06
Physiological markers of anxiety are increased in children of abused mothers. J Child Psychol Psychiatry (2011) 1.06
Olfactory-mediated fear conditioning in mice: simultaneous measurements of fear-potentiated startle and freezing. Behav Neurosci (2005) 1.06
Perceived neighborhood disorder, community cohesion, and PTSD symptoms among low-income African Americans in an urban health setting. Am J Orthopsychiatry (2011) 1.05
The orbitofrontal cortex regulates outcome-based decision-making via the lateral striatum. Eur J Neurosci (2013) 1.05
Wnt signaling in amygdala-dependent learning and memory. J Neurosci (2011) 1.05
The dynamic role of beta-catenin in synaptic plasticity. Neuropharmacology (2011) 1.04
Distinct subtypes of cholecystokinin (CCK)-containing interneurons of the basolateral amygdala identified using a CCK promoter-specific lentivirus. J Neurophysiol (2009) 1.03
T lymphocytes and vascular inflammation contribute to stress-dependent hypertension. Biol Psychiatry (2012) 1.03
PACAP receptor gene polymorphism impacts fear responses in the amygdala and hippocampus. Proc Natl Acad Sci U S A (2014) 1.02
Cell-type specific deletion of GABA(A)α1 in corticotropin-releasing factor-containing neurons enhances anxiety and disrupts fear extinction. Proc Natl Acad Sci U S A (2012) 1.02
Association of genetic variants in the neurotrophic receptor-encoding gene NTRK2 and a lifetime history of suicide attempts in depressed patients. Arch Gen Psychiatry (2010) 1.02
Differential regional expression of brain-derived neurotrophic factor following olfactory fear learning. Learn Mem (2007) 1.01
The neurobiology of anxiety disorders: brain imaging, genetics, and psychoneuroendocrinology. Psychiatr Clin North Am (2009) 1.00
The protective role of friendship on the effects of childhood abuse and depression. Depress Anxiety (2009) 1.00
Functional interactions between endocannabinoid and CCK neurotransmitter systems may be critical for extinction learning. Neuropsychopharmacology (2008) 1.00
Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response. Arch Gen Psychiatry (2010) 1.00
Deoxygedunin, a natural product with potent neurotrophic activity in mice. PLoS One (2010) 0.99
Modulation of fear and anxiety by the endogenous cannabinoid system. CNS Spectr (2007) 0.99
A DTI tractography analysis of infralimbic and prelimbic connectivity in the mouse using high-throughput MRI. Neuroimage (2012) 0.98
Neuropeptide regulation of fear and anxiety: Implications of cholecystokinin, endogenous opioids, and neuropeptide Y. Physiol Behav (2012) 0.98
Differential Genetic and Epigenetic Regulation of catechol-O-methyltransferase is Associated with Impaired Fear Inhibition in Posttraumatic Stress Disorder. Front Behav Neurosci (2013) 0.98
Prepulse inhibition deficits in GAD65 knockout mice and the effect of antipsychotic treatment. Neuropsychopharmacology (2004) 0.97
Specificity of olfactory receptor interactions with other G protein-coupled receptors. J Biol Chem (2007) 0.97
A role for WNT/β-catenin signaling in the neural mechanisms of behavior. J Neuroimmune Pharmacol (2012) 0.97
Thy1-expressing neurons in the basolateral amygdala may mediate fear inhibition. J Neurosci (2013) 0.97
The neurobiology of anxiety disorders: brain imaging, genetics, and psychoneuroendocrinology. Clin Lab Med (2010) 0.96
Family environment and adult resilience: contributions of positive parenting and the oxytocin receptor gene. Eur J Psychotraumatol (2013) 0.95
From the neurobiology of extinction to improved clinical treatments. Depress Anxiety (2013) 0.94
Learning and memory deficits in mice lacking protease activated receptor-1. Neurobiol Learn Mem (2007) 0.93
Inhibition of fear is differentially associated with cycling estrogen levels in women. J Psychiatry Neurosci (2013) 0.93
A novel transgenic mouse for gene-targeting within cells that express corticotropin-releasing factor. Biol Psychiatry (2010) 0.93
The Use of Lentiviral Vectors and Cre/loxP to Investigate the Function of Genes in Complex Behaviors. Front Mol Neurosci (2009) 0.93
Construction of cell-type specific promoter lentiviruses for optically guiding electrophysiological recordings and for targeted gene delivery. Methods Mol Biol (2009) 0.93
Neuronal Abelson helper integration site-1 (Ahi1) deficiency in mice alters TrkB signaling with a depressive phenotype. Proc Natl Acad Sci U S A (2010) 0.92
Amygdala-specific reduction of alpha1-GABAA receptors disrupts the anticonvulsant, locomotor, and sedative, but not anxiolytic, effects of benzodiazepines in mice. J Neurosci (2010) 0.92