Published in Nature on November 07, 2002
Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia. Am J Psychiatry (2007) 8.87
Neural mechanisms of extinction learning and retrieval. Neuropsychopharmacology (2007) 7.57
Emotional processing in anterior cingulate and medial prefrontal cortex. Trends Cogn Sci (2010) 6.88
Prefrontal-subcortical pathways mediating successful emotion regulation. Neuron (2008) 6.68
A neural model of voluntary and automatic emotion regulation: implications for understanding the pathophysiology and neurodevelopment of bipolar disorder. Mol Psychiatry (2008) 5.06
Neurobiological basis of failure to recall extinction memory in posttraumatic stress disorder. Biol Psychiatry (2009) 4.84
The neurocircuitry of fear, stress, and anxiety disorders. Neuropsychopharmacology (2010) 4.82
Functional grouping and cortical-subcortical interactions in emotion: a meta-analysis of neuroimaging studies. Neuroimage (2008) 4.62
Plastic synaptic networks of the amygdala for the acquisition, expression, and extinction of conditioned fear. Physiol Rev (2010) 4.59
Fear extinction as a model for translational neuroscience: ten years of progress. Annu Rev Psychol (2012) 4.04
Dissociable roles of prelimbic and infralimbic cortices, ventral hippocampus, and basolateral amygdala in the expression and extinction of conditioned fear. Neuropsychopharmacology (2010) 3.96
Sustained conditioned responses in prelimbic prefrontal neurons are correlated with fear expression and extinction failure. J Neurosci (2009) 3.76
Extinction circuits for fear and addiction overlap in prefrontal cortex. Learn Mem (2009) 3.62
A genetic variant BDNF polymorphism alters extinction learning in both mouse and human. Science (2010) 3.61
Microstimulation reveals opposing influences of prelimbic and infralimbic cortex on the expression of conditioned fear. Learn Mem (2006) 3.52
Amygdala intercalated neurons are required for expression of fear extinction. Nature (2008) 3.37
Different mechanisms of fear extinction dependent on length of time since fear acquisition. Learn Mem (2006) 3.30
Neural circuitry underlying the regulation of conditioned fear and its relation to extinction. Neuron (2008) 3.23
Amygdala and ventrolateral prefrontal cortex activation to masked angry faces in children and adolescents with generalized anxiety disorder. Arch Gen Psychiatry (2008) 3.22
Context-dependent human extinction memory is mediated by a ventromedial prefrontal and hippocampal network. J Neurosci (2006) 3.17
Histone modifications around individual BDNF gene promoters in prefrontal cortex are associated with extinction of conditioned fear. Learn Mem (2007) 2.99
Neural circuits and mechanisms involved in Pavlovian fear conditioning: a critical review. Neurosci Biobehav Rev (2005) 2.91
Antidepressant effect of optogenetic stimulation of the medial prefrontal cortex. J Neurosci (2010) 2.84
A unified framework for addiction: vulnerabilities in the decision process. Behav Brain Sci (2008) 2.83
The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission. Nat Rev Neurosci (2011) 2.82
Thickness of ventromedial prefrontal cortex in humans is correlated with extinction memory. Proc Natl Acad Sci U S A (2005) 2.78
Fear conditioning and extinction differentially modify the intrinsic excitability of infralimbic neurons. J Neurosci (2008) 2.77
Towards a theory of chronic pain. Prog Neurobiol (2008) 2.76
The brain on stress: vulnerability and plasticity of the prefrontal cortex over the life course. Neuron (2013) 2.59
The structural and functional connectivity of the amygdala: from normal emotion to pathological anxiety. Behav Brain Res (2011) 2.58
Memory for extinction of conditioned fear is long-lasting and persists following spontaneous recovery. Learn Mem (2002) 2.57
Brain mediators of cardiovascular responses to social threat: part I: Reciprocal dorsal and ventral sub-regions of the medial prefrontal cortex and heart-rate reactivity. Neuroimage (2009) 2.46
Synaptic correlates of fear extinction in the amygdala. Nat Neurosci (2010) 2.38
Amygdala and ventrolateral prefrontal cortex function during anticipated peer evaluation in pediatric social anxiety. Arch Gen Psychiatry (2008) 2.37
The structural integrity of an amygdala-prefrontal pathway predicts trait anxiety. J Neurosci (2009) 2.35
Stress-induced prefrontal reorganization and executive dysfunction in rodents. Neurosci Biobehav Rev (2008) 2.33
Induction of fear extinction with hippocampal-infralimbic BDNF. Science (2010) 2.27
How the neurocircuitry and genetics of fear inhibition may inform our understanding of PTSD. Am J Psychiatry (2010) 2.24
Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective. Nat Rev Neurosci (2013) 2.23
Opposite effects of fear conditioning and extinction on dendritic spine remodelling. Nature (2012) 2.19
Changing fear: the neurocircuitry of emotion regulation. Neuropsychopharmacology (2010) 2.18
Resting-state connectivity biomarkers define neurophysiological subtypes of depression. Nat Med (2016) 2.12
Amygdala BDNF signaling is required for consolidation but not encoding of extinction. Nat Neurosci (2006) 2.10
Reciprocal patterns of c-Fos expression in the medial prefrontal cortex and amygdala after extinction and renewal of conditioned fear. Learn Mem (2009) 2.03
A review of adversity, the amygdala and the hippocampus: a consideration of developmental timing. Front Hum Neurosci (2010) 2.00
Role of ventral medial prefrontal cortex in incubation of cocaine craving. Neuropharmacology (2008) 1.99
Stress and anxiety: structural plasticity and epigenetic regulation as a consequence of stress. Neuropharmacology (2011) 1.98
From circuits to behaviour in the amygdala. Nature (2015) 1.97
Anxiety dissociates dorsal and ventral medial prefrontal cortex functional connectivity with the amygdala at rest. Cereb Cortex (2010) 1.95
Context-dependent neuronal activity in the lateral amygdala represents fear memories after extinction. J Neurosci (2003) 1.94
Neural and cellular mechanisms of fear and extinction memory formation. Neurosci Biobehav Rev (2012) 1.94
Cognitive processes during fear acquisition and extinction in animals and humans: implications for exposure therapy of anxiety disorders. Clin Psychol Rev (2007) 1.93
Infralimbic cortex activation increases c-Fos expression in intercalated neurons of the amygdala. Neuroscience (2005) 1.91
Targeting extinction and reconsolidation mechanisms to combat the impact of drug cues on addiction. Neuropharmacology (2008) 1.84
Social neuroscience and health: neurophysiological mechanisms linking social ties with physical health. Nat Neurosci (2012) 1.81
Seeking a spotless mind: extinction, deconsolidation, and erasure of fear memory. Neuron (2011) 1.80
Hippocampal and prefrontal projections to the basal amygdala mediate contextual regulation of fear after extinction. J Neurosci (2011) 1.77
Altered fear learning across development in both mouse and human. Proc Natl Acad Sci U S A (2012) 1.77
Emotion, cognition, and mental state representation in amygdala and prefrontal cortex. Annu Rev Neurosci (2010) 1.76
mGluR5 has a critical role in inhibitory learning. J Neurosci (2009) 1.76
Amygdala microcircuits controlling learned fear. Neuron (2014) 1.75
Pavlovian fear memory induced by activation in the anterior cingulate cortex. Mol Pain (2005) 1.73
Prelimbic cortical BDNF is required for memory of learned fear but not extinction or innate fear. Proc Natl Acad Sci U S A (2010) 1.72
Fear extinction causes target-specific remodeling of perisomatic inhibitory synapses. Neuron (2013) 1.72
Implications of memory modulation for post-traumatic stress and fear disorders. Nat Neurosci (2013) 1.72
Estrous cycle phase and gonadal hormones influence conditioned fear extinction. Neuroscience (2009) 1.72
Stress, sex, and neural adaptation to a changing environment: mechanisms of neuronal remodeling. Ann N Y Acad Sci (2010) 1.71
The storm and stress of adolescence: insights from human imaging and mouse genetics. Dev Psychobiol (2010) 1.71
Sleep-specific mechanisms underlying posttraumatic stress disorder: integrative review and neurobiological hypotheses. Sleep Med Rev (2007) 1.69
The bed nucleus of the stria terminalis mediates inter-individual variations in anxiety and fear. J Neurosci (2009) 1.69
The default-mode, ego-functions and free-energy: a neurobiological account of Freudian ideas. Brain (2010) 1.69
Structural and functional alterations to rat medial prefrontal cortex following chronic restraint stress and recovery. Neuroscience (2009) 1.68
Overlapping neural systems mediating extinction, reversal and regulation of fear. Trends Cogn Sci (2010) 1.67
The infralimbic cortex regulates the consolidation of extinction after cocaine self-administration. Learn Mem (2010) 1.66
Fear and safety engage competing patterns of theta-gamma coupling in the basolateral amygdala. Neuron (2014) 1.64
Adolescence: what do transmission, transition, and translation have to do with it? Neuron (2010) 1.61
Chronic alcohol remodels prefrontal neurons and disrupts NMDAR-mediated fear extinction encoding. Nat Neurosci (2012) 1.61
The role of the medial prefrontal cortex-amygdala circuit in stress effects on the extinction of fear. Neural Plast (2007) 1.59
Altered resting-state amygdala functional connectivity in men with posttraumatic stress disorder. J Psychiatry Neurosci (2012) 1.58
Avoiding negative outcomes: tracking the mechanisms of avoidance learning in humans during fear conditioning. Front Behav Neurosci (2009) 1.57
The human amygdala and orbital prefrontal cortex in behavioural regulation. Philos Trans R Soc Lond B Biol Sci (2007) 1.52
Retrieval of emotional memories. Psychol Bull (2007) 1.52
Synaptic encoding of fear extinction in mPFC-amygdala circuits. Neuron (2013) 1.52
A history of corticosterone exposure regulates fear extinction and cortical NR2B, GluR2/3, and BDNF. Neuropsychopharmacology (2008) 1.51
Attachment figures activate a safety signal-related neural region and reduce pain experience. Proc Natl Acad Sci U S A (2011) 1.51
Glutamate receptors in extinction and extinction-based therapies for psychiatric illness. Neuropsychopharmacology (2010) 1.51
Estradiol modulates medial prefrontal cortex and amygdala activity during fear extinction in women and female rats. Biol Psychiatry (2011) 1.51
Extinction memory is impaired in schizophrenia. Biol Psychiatry (2008) 1.50
Functional anatomy of ventromedial prefrontal cortex: implications for mood and anxiety disorders. Mol Psychiatry (2011) 1.47
Variant BDNF Val66Met polymorphism affects extinction of conditioned aversive memory. J Neurosci (2009) 1.46
Impaired extinction retention in adolescent rats: effects of D-cycloserine. Neuropsychopharmacology (2010) 1.45
Sex differences, gonadal hormones and the fear extinction network: implications for anxiety disorders. Biol Mood Anxiety Disord (2012) 1.44
Differentiating neural systems mediating the acquisition vs. expression of goal-directed and habitual behavioral control. Eur J Neurosci (2015) 1.43
Role of corticotropin releasing factor in anxiety disorders: a translational research perspective. Horm Behav (2006) 1.43
Hippocampal regulation of context-dependent neuronal activity in the lateral amygdala. Learn Mem (2007) 1.42
Posttraumatic stress disorder: the role of medial prefrontal cortex and amygdala. Neuroscientist (2009) 1.39
Cerebral blood flow in immediate and sustained anxiety. J Neurosci (2007) 1.38
Functional anatomy of neural circuits regulating fear and extinction. Proc Natl Acad Sci U S A (2012) 1.38
Electrolytic lesions of the medial prefrontal cortex do not interfere with long-term memory of extinction of conditioned fear. Learn Mem (2006) 1.37
Developmental trajectories during adolescence in males and females: a cross-species understanding of underlying brain changes. Neurosci Biobehav Rev (2011) 1.35
Neuronal signalling of fear memory. Nat Rev Neurosci (2004) 7.03
Recall of fear extinction in humans activates the ventromedial prefrontal cortex and hippocampus in concert. Biol Psychiatry (2007) 5.56
New vistas on amygdala networks in conditioned fear. J Neurophysiol (2004) 4.44
Fear extinction as a model for translational neuroscience: ten years of progress. Annu Rev Psychol (2012) 4.04
Dissociable roles of prelimbic and infralimbic cortices, ventral hippocampus, and basolateral amygdala in the expression and extinction of conditioned fear. Neuropsychopharmacology (2010) 3.96
Sustained conditioned responses in prelimbic prefrontal neurons are correlated with fear expression and extinction failure. J Neurosci (2009) 3.76
Extinction circuits for fear and addiction overlap in prefrontal cortex. Learn Mem (2009) 3.62
Microstimulation reveals opposing influences of prelimbic and infralimbic cortex on the expression of conditioned fear. Learn Mem (2006) 3.52
Consolidation of fear extinction requires NMDA receptor-dependent bursting in the ventromedial prefrontal cortex. Neuron (2007) 3.32
Fear extinction in rats: implications for human brain imaging and anxiety disorders. Biol Psychol (2006) 3.32
Prefrontal control of fear: more than just extinction. Curr Opin Neurobiol (2010) 3.10
Consolidation of fear extinction requires protein synthesis in the medial prefrontal cortex. J Neurosci (2004) 2.88
Activity in prelimbic cortex is necessary for the expression of learned, but not innate, fears. J Neurosci (2007) 2.82
A role for the human dorsal anterior cingulate cortex in fear expression. Biol Psychiatry (2007) 2.78
Fear conditioning and extinction differentially modify the intrinsic excitability of infralimbic neurons. J Neurosci (2008) 2.77
Induction of fear extinction with hippocampal-infralimbic BDNF. Science (2010) 2.27
Delayed recall of fear extinction in rats with lesions of ventral medial prefrontal cortex. Learn Mem (2004) 2.09
Gating of fear in prelimbic cortex by hippocampal and amygdala inputs. Neuron (2012) 2.06
Lesions of the basal amygdala block expression of conditioned fear but not extinction. J Neurosci (2005) 1.87
Noradrenergic signaling in infralimbic cortex increases cell excitability and strengthens memory for fear extinction. J Neurosci (2008) 1.84
Inactivation of the ventromedial prefrontal cortex reduces expression of conditioned fear and impairs subsequent recall of extinction. Eur J Neurosci (2006) 1.82
The brain-derived neurotrophic factor Val66Met polymorphism predicts response to exposure therapy in posttraumatic stress disorder. Biol Psychiatry (2013) 1.54
Deep brain stimulation of the ventral striatum enhances extinction of conditioned fear. Proc Natl Acad Sci U S A (2012) 1.33
Recalling safety: cooperative functions of the ventromedial prefrontal cortex and the hippocampus in extinction. CNS Spectr (2007) 1.20
Systemic propranolol acts centrally to reduce conditioned fear in rats without impairing extinction. Biol Psychiatry (2009) 1.19
Memory for fear extinction requires mGluR5-mediated activation of infralimbic neurons. Cereb Cortex (2010) 1.18
Pharmacological facilitation of fear extinction and the search for adjunct treatments for anxiety disorders--the case of yohimbine. Trends Pharmacol Sci (2009) 1.17
Infralimbic D2 receptors are necessary for fear extinction and extinction-related tone responses. Biol Psychiatry (2010) 1.11
Resting amygdala and medial prefrontal metabolism predicts functional activation of the fear extinction circuit. Am J Psychiatry (2012) 1.09
A biologically realistic network model of acquisition and extinction of conditioned fear associations in lateral amygdala neurons. J Neurophysiol (2008) 1.03
A time-dependent role of midline thalamic nuclei in the retrieval of fear memory. Neuropharmacology (2011) 1.00
Prelimbic and infralimbic neurons signal distinct aspects of appetitive instrumental behavior. PLoS One (2013) 0.98
Deep brain stimulation of the ventral striatum increases BDNF in the fear extinction circuit. Front Behav Neurosci (2013) 0.98
The effects of yohimbine and amphetamine on fear expression and extinction in rats. Psychopharmacology (Berl) (2009) 0.92
Neuroscience: Editing out fear. Nature (2010) 0.85
Fear signaling in the prelimbic-amygdala circuit: a computational modeling and recording study. J Neurophysiol (2013) 0.83
Extending fear extinction beyond anxiety disorders. Biol Psychiatry (2009) 0.78
The effect of repeated exposure to ethanol on pre-existing fear memories in rats. Psychopharmacology (Berl) (2015) 0.77
Keeping the memories flowing. Nat Neurosci (2006) 0.75