Published in J Physiol on March 01, 1991
Nomenclature and classification of purinoceptors. Pharmacol Rev (1994) 5.32
Ionic permeability of, and divalent cation effects on, two ATP-gated cation channels (P2X receptors) expressed in mammalian cells. J Physiol (1996) 2.07
Differential distribution of two ATP-gated channels (P2X receptors) determined by immunocytochemistry. Proc Natl Acad Sci U S A (1996) 1.86
Neuromodulation by extracellular ATP and P2X receptors in the CNS. Neuron (2012) 1.70
Full sensitivity of P2X2 purinoceptor to ATP revealed by changing extracellular pH. Br J Pharmacol (1996) 1.57
Molecular properties of P2X receptors. Pflugers Arch (2006) 1.47
On the excitatory effects of ATP and its role as a neurotransmitter in coeliac neurons of the guinea-pig. J Physiol (1993) 1.29
Block by calcium of ATP-activated channels in pheochromocytoma cells. J Gen Physiol (1993) 1.23
Purinergic signalling and cancer. Purinergic Signal (2013) 1.18
Non-additive interaction between nicotinic cholinergic and P2X purine receptors in guinea-pig enteric neurons in culture. J Physiol (1998) 1.17
Functional interactions between nicotinic and P2X channels in short-term cultures of guinea-pig submucosal neurons. J Physiol (1998) 1.14
Mutual occlusion of P2X ATP receptors and nicotinic receptors on sympathetic neurons of the guinea-pig. J Physiol (1998) 1.03
Ionic selectivity of native ATP-activated (P2X) receptor channels in dissociated neurones from rat parasympathetic ganglia. J Physiol (2001) 0.97
Cross-inhibition between nicotinic acetylcholine receptors and P2X receptors in myenteric neurons and HEK-293 cells. Am J Physiol Gastrointest Liver Physiol (2009) 0.87
Interaction of P2 purinergic receptors with cellular macromolecules. Naunyn Schmiedebergs Arch Pharmacol (2007) 0.86
Molecular mechanisms of cross-inhibition between nicotinic acetylcholine receptors and P2X receptors in myenteric neurons and HEK-293 cells. Neurogastroenterol Motil (2010) 0.80
P2X receptors. Philos Trans R Soc Lond B Biol Sci (2016) 0.79
Cross-talk between apparently independent receptors. J Physiol (1998) 0.76
Methyllycaconitine, alpha-bungarotoxin and (+)-tubocurarine block fast ATP-gated currents in rat dorsal root ganglion cells. Br J Pharmacol (2004) 0.75
Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch (1981) 134.60
On the stochastic properties of single ion channels. Proc R Soc Lond B Biol Sci (1981) 11.30
Extracellular ATP: effects, sources and fate. Biochem J (1986) 8.45
A novel receptor-operated Ca2+-permeable channel activated by ATP in smooth muscle. Nature (1987) 5.94
Suramin: a reversible P2-purinoceptor antagonist in the mouse vas deferens. Br J Pharmacol (1988) 4.52
On the mechanism of activation of muscarinic K+ channels by adenosine in isolated atrial cells: involvement of GTP-binding proteins. Pflugers Arch (1986) 2.81
Studies on the mechanism of action of acetylcholine antagonists on rat parasympathetic ganglion cells. J Physiol (1979) 2.67
Action of externally applied adenosine triphosphate on single smooth muscle cells dispersed from rabbit ear artery. J Physiol (1987) 2.58
Nerve growth factor-induced increase in electrical excitability and acetylcholine sensitivity of a rat pheochromocytoma cell line. Nature (1977) 2.39
ATP-activated channels in rat and bullfrog sensory neurons: concentration dependence and kinetics. J Neurosci (1990) 2.18
An ATP-sensitive conductance in single smooth muscle cells from the rat vas deferens. J Physiol (1988) 1.78
M currents. Ion Channels (1988) 1.59
Transmitter-like action of ATP on patched membranes of cultured myoblasts and myotubes. Nature (1983) 1.58
The inhibitory action of suramin on the P2-purinoceptor response in smooth muscle cells of guinea-pig taenia caeci. Eur J Pharmacol (1989) 1.55
An ATP-activated conductance in pheochromocytoma cells and its suppression by extracellular calcium. J Physiol (1990) 1.51
ATP-activated channels in rat and bullfrog sensory neurons: current-voltage relation and single-channel behavior. J Neurosci (1990) 1.49
The action of ganglionic blocking drugs on the synaptic responses of rat submandibular ganglion cells. Br J Pharmacol (1982) 1.46
Cationic channels activated by extracellular ATP in rat sensory neurons. Neuroscience (1988) 1.45
Adenosine triphosphate-activated inward current in isolated smooth muscle cells from rat vas deferens. Pflugers Arch (1987) 1.43
ATP-activated channels in excitable cells. Ion Channels (1990) 1.39
Receptors for ATP in rat sensory neurones: the structure-function relationship for ligands. Br J Pharmacol (1988) 1.38
Extracellular adenosine 5'-triphosphate-evoked norepinephrine secretion not relating to voltage-gated Ca channels in pheochromocytoma PC12 cells. Neurosci Lett (1989) 1.34
An ATP-sensitive conductance in cultured smooth muscle cells from pregnant rat myometrium. Am J Physiol (1989) 1.34
Reversible and selective antagonism by suramin of ATP-activated inward current in PC12 phaeochromocytoma cells. Br J Pharmacol (1990) 1.31
Muscarinic stimulation of calcium influx and norepinephrine release in PC12 cells. J Biol Chem (1988) 1.31
Adenosine 5'-triphosphate activates acetylcholine receptor channels in cultured Xenopus myotomal muscle cells. J Physiol (1988) 1.16
Voltage dependent calcium currents in PC12 growth cones and cells during NGF-induced cell growth. Pflugers Arch (1987) 1.07
Morphological properties and membrane channels of the growth cones induced in PC12 cells by nerve growth factor. J Neurosci Res (1985) 0.98
N-methyl-D-aspartate activates different channels than do kainate and quisqualate. Proc Natl Acad Sci U S A (1989) 0.94
Existence of muscarinic suppression of a K current in PC-12 pheochromocytoma cells. Am J Physiol (1989) 0.91
Regulation of sodium currents and acetylcholine responses in PC12 cells. Brain Res (1990) 0.90
Increased sodium ion conductance through nicotinic acetylcholine receptor channels in PC12 cells exposed to nerve growth factors. J Neurosci (1983) 0.82
Increase of carbamylcholine-induced 22Na+ influx into pheochromocytoma PC12h cells by nerve growth factor. Brain Res (1984) 0.79
Proposed supplements and amendments to 'A Manual of Standardized Terminology, Techniques and Scoring System for Sleep Stages of Human Subjects', the Rechtschaffen & Kales (1968) standard. Psychiatry Clin Neurosci (2001) 36.50
IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J Clin Invest (1999) 7.66
Clinical application of transvenous mitral commissurotomy by a new balloon catheter. J Thorac Cardiovasc Surg (1984) 4.45
Molecular evidence for the early evolution of photosynthesis. Science (2000) 4.17
Real-time detection system for quantification of hepatitis C virus genome. Gastroenterology (1999) 3.83
Inter-mitochondrial complementation: Mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA. Nat Med (2001) 3.81
Results of surgical and nonsurgical treatment for small-sized hepatocellular carcinomas: a retrospective and nationwide survey in Japan. The Liver Cancer Study Group of Japan. Hepatology (2000) 3.42
Control of doublesex alternative splicing by transformer and transformer-2 in Drosophila. Science (1991) 2.87
Myeloscopy, with special reference to blood flow changes in the cauda equina during Lasègue's test. Int Orthop (1981) 2.82
Experimental investigation of geologically produced antineutrinos with KamLAND. Nature (2005) 2.75
Requirement of CD9 on the egg plasma membrane for fertilization. Science (2000) 2.65
Enhanced expression of a glyceraldehyde-3-phosphate dehydrogenase gene in human lung cancers. Cancer Res (1987) 2.65
Tumor angiogenesis in human lung adenocarcinoma. Cancer (1994) 2.59
Extracellular ATP or ADP induce chemotaxis of cultured microglia through Gi/o-coupled P2Y receptors. J Neurosci (2001) 2.54
No-mortality liver resection for hepatocellular carcinoma in cirrhotic and noncirrhotic patients: is there a way? A prospective analysis of our approach. Arch Surg (1999) 2.47
Quantitation of hepatitis B virus genomic DNA by real-time detection PCR. J Clin Microbiol (1999) 2.46
Molecular cloning and characterization of a novel human G-protein-coupled receptor, EDG7, for lysophosphatidic acid. J Biol Chem (1999) 2.44
Interferon-alpha-mediated down-regulation of angiogenesis-related genes and therapy of bladder cancer are dependent on optimization of biological dose and schedule. Clin Cancer Res (1999) 2.39
Ultrasonically guided percutaneous microwave coagulation therapy for small hepatocellular carcinoma. Cancer (1994) 2.34
Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice. Clin Cancer Res (1999) 2.26
Downregulation of caffeic acid 3-O-methyltransferase and caffeoyl CoA 3-O-methyltransferase in transgenic alfalfa. impacts on lignin structure and implications for the biosynthesis of G and S lignin. Plant Cell (2001) 2.23
Miller-Dieker lissencephaly gene encodes a subunit of brain platelet-activating factor acetylhydrolase [corrected]. Nature (1994) 2.22
Molecular cloning and nucleotide sequence of the cDNA for rat peroxisomal enoyl-CoA: hydratase-3-hydroxyacyl-CoA dehydrogenase bifunctional enzyme. J Biol Chem (1985) 2.12
Role of human cytochrome P4502A6 in C-oxidation of nicotine. Drug Metab Dispos (1996) 2.11
Phage-conversion of toxigenicity in Clostridium botulinum types C and D. Jpn J Med Sci Biol (1971) 2.09
Over-expression of facilitative glucose transporter genes in human cancer. Biochem Biophys Res Commun (1990) 2.06
Ataxia with isolated vitamin E deficiency is caused by mutations in the alpha-tocopherol transfer protein. Nat Genet (1995) 2.03
Lysenin, a novel sphingomyelin-specific binding protein. J Biol Chem (1998) 2.02
Postmarketing surveillance of the safety profile of infliximab in 5000 Japanese patients with rheumatoid arthritis. Ann Rheum Dis (2007) 2.01
Autosomal dominant moyamoya disease maps to chromosome 17q25.3. Neurology (2008) 2.00
VCP/p97 in abnormal protein aggregates, cytoplasmic vacuoles, and cell death, phenotypes relevant to neurodegeneration. Cell Death Differ (2001) 2.00
Conversion of toxigenicity in Clostridium botulinum type C. Jpn J Microbiol (1970) 1.98
Did ossification of the posterior longitudinal ligament of the spine evolve in the modern period? A paleopathologic study of ancient human skeletons in Japan. J Rheumatol (2000) 1.96
Fungal metabolites. Part 11. A potent immunosuppressive activity found in Isaria sinclairii metabolite. J Antibiot (Tokyo) (1994) 1.93
A unique vacuolar processing enzyme responsible for conversion of several proprotein precursors into the mature forms. FEBS Lett (1991) 1.92
Bacteriophages of Clostridium botulinum. J Virol (1968) 1.88
Monoclonal antibodies to mouse complement receptor type 1 (CR1). Their use in a distribution study showing that mouse erythrocytes and platelets are CR1-negative. J Immunol (1988) 1.86
Molecular composition of Clostridium botulinum type A progenitor toxins. Infect Immun (1996) 1.82
Friedreich-like ataxia with retinitis pigmentosa caused by the His101Gln mutation of the alpha-tocopherol transfer protein gene. Ann Neurol (1997) 1.81
Biochemical identification of Xenopus Pumilio as a sequence-specific cyclin B1 mRNA-binding protein that physically interacts with a Nanos homolog, Xcat-2, and a cytoplasmic polyadenylation element-binding protein. J Biol Chem (2001) 1.81
Redistribution of phosphatidylethanolamine at the cleavage furrow of dividing cells during cytokinesis. Proc Natl Acad Sci U S A (1996) 1.81
Balanced biosynthesis of major membrane components through regulated degradation of the committed enzyme of lipid A biosynthesis by the AAA protease FtsH (HflB) in Escherichia coli. Mol Microbiol (1999) 1.80
Adult-onset spinocerebellar dysfunction caused by a mutation in the gene for the alpha-tocopherol-transfer protein. N Engl J Med (1995) 1.77
A secondary structure at the 3' splice site affects the in vitro splicing reaction of mouse immunoglobulin mu chain pre-mRNAs. Nucleic Acids Res (1989) 1.77
Affinity for alpha-tocopherol transfer protein as a determinant of the biological activities of vitamin E analogs. FEBS Lett (1997) 1.74
Characterization of CYP2A6 involved in 3'-hydroxylation of cotinine in human liver microsomes. J Pharmacol Exp Ther (1996) 1.74
Accurate preoperative evaluation of liver mass lesions without fine-needle biopsy. Hepatology (1999) 1.73
Possible link between large artery stiffness and coronary flow velocity reserve. Heart (2007) 1.72
Molecular mechanisms of Spemann's organizer formation: conserved growth factor synergy between Xenopus and mouse. Genes Dev (1995) 1.71
Modulation of transforming growth factor beta function in hepatocytes and hepatic stellate cells in rat liver injury. Gut (2000) 1.70
[Studies on the immune bacteriolysis. XIV. Requirement of all nine components of complement for immune bacteriolysis]. Biken J (1968) 1.70
Peripheral administration of nesfatin-1 reduces food intake in mice: the leptin-independent mechanism. Endocrinology (2008) 1.69
Percutaneous microwave coagulation therapy for solitary metastatic liver tumors from colorectal cancer: a pilot clinical study. Am J Gastroenterol (1999) 1.69
Control of Drosophila Sex-lethal pre-mRNA splicing by its own female-specific product. Nucleic Acids Res (1992) 1.68
Scavenger receptor-mediated uptake and metabolism of lipid vesicles containing acidic phospholipids by mouse peritoneal macrophages. J Biol Chem (1990) 1.67
Expression of P-glycoprotein in human placenta: relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene. J Pharmacol Exp Ther (2001) 1.65
15-deoxy-delta(12,14)-PGJ(2) induces synoviocyte apoptosis and suppresses adjuvant-induced arthritis in rats. J Clin Invest (2000) 1.64
Cytokine production in the infrapatellar fat pad: another source of cytokines in knee synovial fluids. Ann Rheum Dis (2003) 1.64
The evolutionary chromosome translocation 4;19 in Gorilla gorilla is associated with microduplication of the chromosome fragment syntenic to sequences surrounding the human proximal CMT1A-REP. Genome Res (2001) 1.64
Extracellular ATP triggers tumor necrosis factor-alpha release from rat microglia. J Neurochem (2000) 1.63
Exposure of phosphatidylethanolamine on the surface of apoptotic cells. Exp Cell Res (1997) 1.61
Sterol regulatory element-binding proteins induce an entire pathway of cholesterol synthesis. Biochem Biophys Res Commun (2001) 1.61
A randomized clinical trial of pouch reconstruction after total gastrectomy for cancer: which is the better technique, Roux-en-Y or interposition? Hepatogastroenterology (2001) 1.61
Structure and function of Clostridium botulinum toxins. Microbiol Immunol (1995) 1.60
Selective expression of a protein-tyrosine kinase, p56lyn, in hematopoietic cells and association with production of human T-cell lymphotropic virus type I. Proc Natl Acad Sci U S A (1989) 1.59
Vesicle transport and processing of the precursor to 2S albumin in pumpkin. Plant J (1993) 1.58
Hemolysins and related enzymes of Vibrio parahaemolyticus. I. Identification and partial purification of enzymes. Biken J (1970) 1.57
Percutaneous microwave coagulation therapy for patients with small hepatocellular carcinoma: comparison with percutaneous ethanol injection therapy. Cancer (1999) 1.56
Augmented interleukin-1 production and HLA-DR expression in the synovium of rheumatoid arthritis patients. Possible involvement in joint destruction. Arthritis Rheum (1988) 1.54
Inhibition of human lung cancer cell growth by the peroxisome proliferator-activated receptor-gamma agonists through induction of apoptosis. Biochem Biophys Res Commun (2000) 1.52
Anti-manic and prophylactic effects of carbamazepine (Tegretol) on manic depressive psychosis. A preliminary report. Folia Psychiatr Neurol Jpn (1973) 1.52
Mammalian non-pancreatic phospholipases A2. Biochim Biophys Acta (1993) 1.52
Catalytic properties of polymorphic human cytochrome P450 1B1 variants. Carcinogenesis (1999) 1.52
An ATP-activated conductance in pheochromocytoma cells and its suppression by extracellular calcium. J Physiol (1990) 1.51
Hepatic infarction following percutaneous ethanol injection therapy for hepatocellular carcinoma. Eur J Gastroenterol Hepatol (1998) 1.51
Metabolism of benzo[a]pyrene to trans-7,8-dihydroxy-7, 8-dihydrobenzo[a]pyrene by recombinant human cytochrome P450 1B1 and purified liver epoxide hydrolase. Chem Res Toxicol (1999) 1.51
The isolation and characterization of a ninth component of hemolytic complement, C'3f. J Immunol (1966) 1.51
Inhibitory effect of K-76 monocarboxylic acid, an anticomplementary agent, on the C3b inactivator system. J Immunol (1981) 1.50
Treatment of roentogenographically occult endobronchial carcinoma with external beam radiotherapy and intraluminal low dose rate brachytherapy. Int J Radiat Oncol Biol Phys (1996) 1.50
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Genome Res (2000) 1.50
Inflammatory pseudotumors of the liver: prevalence and clinical impact in surgical patients. Hepatogastroenterology (2001) 1.49
Antigenicity of converting phages obtained from Clostridium botulinum types C and D. Infect Immun (1976) 1.49
Isoform-dependent differences in feedback regulation and subcellular localization of serine acetyltransferase involved in cysteine biosynthesis from Arabidopsis thaliana. J Biol Chem (1998) 1.47
Lysophosphatidic acid (LPA) receptors of the EDG family are differentially activated by LPA species. Structure-activity relationship of cloned LPA receptors. FEBS Lett (2000) 1.47
Patterns of internal echoes in lymph nodes in the diagnosis of lung cancer metastasis. World J Surg (1993) 1.47
Identification of a PDZ-domain-containing protein that interacts with the scavenger receptor class B type I. Proc Natl Acad Sci U S A (2000) 1.47
Measurement of neutrino oscillation with KamLAND: evidence of spectral distortion. Phys Rev Lett (2005) 1.46
The gene for the 9 kd polypeptide, a possible apoprotein for the iron-sulfur centers A and B of the photosystem I complex, in tobacco chloroplast DNA. Curr Genet (1987) 1.46
Regulatory functions of phospholipase A2. Crit Rev Immunol (1997) 1.45
Monocyte chemoattractant protein-1 (MCP-1) in inflammatory joint diseases and its involvement in the cytokine network of rheumatoid synovium. Clin Immunol Immunopathol (1993) 1.45
N-methylnicotinamide is an endogenous probe for evaluation of drug-drug interactions involving multidrug and toxin extrusions (MATE1 and MATE2-K). Clin Pharmacol Ther (2012) 1.45
Increased plasma TGF-beta1 in patients with amyotrophic lateral sclerosis. Acta Neurol Scand (2002) 1.43
Brain acetylhydrolase that inactivates platelet-activating factor is a G-protein-like trimer. Nature (1997) 1.42
Spontaneous production of an interleukin 1-like factor by cloned rheumatoid synovial cells in long-term culture. J Clin Invest (1987) 1.42
Ectopic pancreas in the stomach presenting as an inflammatory abdominal mass. Am J Gastroenterol (1989) 1.41
Heterogeneous distribution of microcirculatory disturbance in the gastric mucosa during gastric hypercontraction in rats. J Gastroenterol Hepatol (1995) 1.41
Chest roentgenogram demonstrates cephalad movement of the carina during laparoscopic cholecystectomy. Anesthesiology (1994) 1.41