A secondary structure at the 3' splice site affects the in vitro splicing reaction of mouse immunoglobulin mu chain pre-mRNAs.

PubWeight™: 1.77‹?› | Rank: Top 3%

🔗 View Article (PMC 334955)

Published in Nucleic Acids Res on October 25, 1989

Authors

A Watakabe1, K Inoue, H Sakamoto, Y Shimura

Author Affiliations

1: Department of Biophysics, Faculty of Science, Kyoto University, Japan.

Articles citing this

Polypurine sequences within a downstream exon function as a splicing enhancer. Mol Cell Biol (1994) 3.15

Influence of RNA secondary structure on the pre-mRNA splicing process. Mol Cell Biol (2004) 3.07

Exonic splicing enhancer motif recognized by human SC35 under splicing conditions. Mol Cell Biol (2000) 3.01

MBNL binds similar RNA structures in the CUG repeats of myotonic dystrophy and its pre-mRNA substrate cardiac troponin T. RNA (2007) 2.58

The Y14 protein communicates to the cytoplasm the position of exon-exon junctions. EMBO J (2001) 2.37

Presence of negative and positive cis-acting RNA splicing elements within and flanking the first tat coding exon of human immunodeficiency virus type 1. Mol Cell Biol (1994) 2.35

Substrate specificities of SR proteins in constitutive splicing are determined by their RNA recognition motifs and composite pre-mRNA exonic elements. Mol Cell Biol (1999) 2.05

A 32-nucleotide exon-splicing enhancer regulates usage of competing 5' splice sites in a differential internal exon. Mol Cell Biol (1995) 1.92

Exon as well as intron sequences are cis-regulating elements for the mutually exclusive alternative splicing of the beta tropomyosin gene. Mol Cell Biol (1990) 1.82

Role of RNA structure in regulating pre-mRNA splicing. Trends Biochem Sci (2009) 1.76

Control of calcitonin/calcitonin gene-related peptide pre-mRNA processing by constitutive intron and exon elements. Mol Cell Biol (1993) 1.76

Short artificial hairpins sequester splicing signals and inhibit yeast pre-mRNA splicing. Mol Cell Biol (1993) 1.73

RNA splicing specificity determined by the coordinated action of RNA recognition motifs in SR proteins. Proc Natl Acad Sci U S A (1997) 1.72

Regulation of fibronectin EDA exon alternative splicing: possible role of RNA secondary structure for enhancer display. Mol Cell Biol (1999) 1.69

Two different sequence elements within exon 4 are necessary for calcitonin-specific splicing of the human calcitonin/calcitonin gene-related peptide I pre-mRNA. Mol Cell Biol (1994) 1.64

Conserved stem-loop structures in the HIV-1 RNA region containing the A3 3' splice site and its cis-regulatory element: possible involvement in RNA splicing. Nucleic Acids Res (2001) 1.37

The developmentally regulated shift from membrane to secreted mu mRNA production is accompanied by an increase in cleavage-polyadenylation efficiency but no measurable change in splicing efficiency. Mol Cell Biol (1991) 1.28

Inhibition of translation by RNA-small molecule interactions. RNA (2002) 1.27

A single nucleotide polymorphism in an exon dictates allele dependent differential splicing of episialin mRNA. Nucleic Acids Res (1991) 1.22

Identification of a specific exon sequence that is a major determinant in the selection between a natural and a cryptic 5' splice site. Mol Cell Biol (1991) 1.21

Exon size affects competition between splicing and cleavage-polyadenylation in the immunoglobulin mu gene. Mol Cell Biol (1994) 1.11

A secondary structure that contains the 5' and 3' splice sites suppresses splicing of duck hepatitis B virus pregenomic RNA. J Virol (2002) 1.06

Alterations of RNase H sensitivity of the 3' splice site region during the in vitro splicing reaction. Nucleic Acids Res (1991) 1.03

The exon junction complex controls transposable element activity by ensuring faithful splicing of the piwi transcript. Genes Dev (2014) 0.99

Live-cell visualization of pre-mRNA splicing with single-molecule sensitivity. Cell Rep (2013) 0.98

Cooperation of 5' and 3' processing sites as well as intron and exon sequences in calcitonin exon recognition. Nucleic Acids Res (1995) 0.97

Conservation of the sizes of 53 introns and over 100 intronic sequences for the binding of common transcription factors in the human and mouse genes for type II procollagen (COL2A1). Biochem J (1995) 0.96

The molecular defect of ferrochelatase in a patient with erythropoietic protoporphyria. Proc Natl Acad Sci U S A (1992) 0.94

The 3' splice site of influenza A segment 7 mRNA can exist in two conformations: a pseudoknot and a hairpin. PLoS One (2012) 0.92

Splicing of constitutive upstream introns is essential for the recognition of intra-exonic suboptimal splice sites in the thrombopoietin gene. Nucleic Acids Res (2001) 0.88

Splice site selection in polyomavirus late pre-mRNA processing. J Virol (1994) 0.83

Identification of U2AF(35)-dependent exons by RNA-Seq reveals a link between 3' splice-site organization and activity of U2AF-related proteins. Nucleic Acids Res (2015) 0.82

The influenza A segment 7 mRNA 3' splice site pseudoknot/hairpin family. RNA Biol (2012) 0.81

Spontaneous deletions in Ig heavy chain genes: flanking sequences influence splice site selection. Nucleic Acids Res (1991) 0.75

Articles cited by this

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res (1983) 124.30

Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc Natl Acad Sci U S A (1985) 68.48

Splicing of messenger RNA precursors. Annu Rev Biochem (1986) 14.41

Tissue-specific in vitro transcription from the mouse albumin promoter. Cell (1986) 10.54

Pre-mRNA splicing. Annu Rev Genet (1986) 9.86

Two mRNAs can be produced from a single immunoglobulin mu gene by alternative RNA processing pathways. Cell (1980) 9.86

Recognition of cap structure in splicing in vitro of mRNA precursors. Cell (1984) 8.67

Specific labeling of 3' termini of RNA with T4 RNA ligase. Methods Enzymol (1980) 7.55

Two mRNAs with different 3' ends encode membrane-bound and secreted forms of immunoglobulin mu chain. Cell (1980) 6.32

The pathway of eukaryotic mRNA formation. Annu Rev Biochem (1983) 6.16

Synthesis of secreted and membrane-bound immunoglobulin mu heavy chains is directed by mRNAs that differ at their 3' ends. Cell (1980) 5.59

Complex transcriptional units: diversity in gene expression by alternative RNA processing. Annu Rev Biochem (1986) 4.73

Alternative splicing caused by RNA secondary structure. Cell (1985) 4.21

Effects of RNA secondary structure on alternative splicing of pre-mRNA: is folding limited to a region behind the transcribing RNA polymerase? Cell (1988) 3.41

The regulated production of mu m and mu s mRNA is dependent on the relative efficiencies of mu s poly(A) site usage and the c mu 4-to-M1 splice. Mol Cell Biol (1989) 2.50

Factors influencing alternative splice site utilization in vivo. Mol Cell Biol (1987) 2.39

The role of nucleotide sequences in splice site selection in eukaryotic pre-messenger RNA. Nature (1987) 2.33

Regulated production of mu m and mu s mRNA requires linkage of the poly(A) addition sites and is dependent on the length of the mu s-mu m intron. Proc Natl Acad Sci U S A (1986) 2.19

Amount of RNA secondary structure required to induce an alternative splice. Mol Cell Biol (1987) 2.19

Relative position and strengths of poly(A) sites as well as transcription termination are critical to membrane versus secreted mu-chain expression during B-cell development. Genes Dev (1987) 2.07

Preferential excision of the 5' proximal intron from mRNA precursors with two introns as mediated by the cap structure. Proc Natl Acad Sci U S A (1987) 2.04

Transcriptional and posttranscriptional control of immunoglobulin mRNA production during B lymphocyte development. Nucleic Acids Res (1986) 1.77

Poly(A) site choice rather than splice site choice governs the regulated production of IgM heavy-chain RNAs. Proc Natl Acad Sci U S A (1988) 1.46

The sequence of the human immunoglobulin mu-delta intron reveals possible vestigial switch segments. Nucleic Acids Res (1984) 1.34

Effects of intron length on differential processing of mouse mu heavy-chain mRNA. Mol Cell Biol (1987) 1.23

Requirement of ATP in the second step of the pre-mRNA splicing reaction. Nucleic Acids Res (1988) 1.18

Regulation of differential processing of mouse immunoglobulin mu heavy-chain mRNA. Nucleic Acids Res (1987) 1.14

In vitro splicing of a chicken delta-crystallin pre-mRNA in a mammalian nuclear extract. J Biochem (1987) 1.08

Nuclear factors in B lymphoma enhance splicing of mouse membrane-bound mu mRNA in Xenopus oocytes. Science (1988) 0.99

Articles by these authors

Proposed supplements and amendments to 'A Manual of Standardized Terminology, Techniques and Scoring System for Sleep Stages of Human Subjects', the Rechtschaffen & Kales (1968) standard. Psychiatry Clin Neurosci (2001) 36.50

Mutational analysis of pistil structure and development of Arabidopsis thaliana. Cell Differ Dev (1989) 14.11

IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J Clin Invest (1999) 7.66

Reversible root tip rotation in Arabidopsis seedlings induced by obstacle-touching stimulus. Science (1990) 7.48

A new protein containing an SH2 domain that inhibits JAK kinases. Nature (1997) 6.28

The Arabidopsis HY5 gene encodes a bZIP protein that regulates stimulus-induced development of root and hypocotyl. Genes Dev (1997) 5.18

The role of exon sequences in splice site selection. Genes Dev (1993) 4.86

Secretion of cyclolysin, the calmodulin-sensitive adenylate cyclase-haemolysin bifunctional protein of Bordetella pertussis. EMBO J (1988) 4.75

Clinical application of transvenous mitral commissurotomy by a new balloon catheter. J Thorac Cardiovasc Surg (1984) 4.45

Molecular evidence for the early evolution of photosynthesis. Science (2000) 4.17

Real-time detection system for quantification of hepatitis C virus genome. Gastroenterology (1999) 3.83

Inter-mitochondrial complementation: Mitochondria-specific system preventing mice from expression of disease phenotypes by mutant mtDNA. Nat Med (2001) 3.81

The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop. EMBO J (1999) 3.77

Epidermal cell differentiation in Arabidopsis determined by a Myb homolog, CPC. Science (1997) 3.59

Structural basis for recognition of the tra mRNA precursor by the Sex-lethal protein. Nature (1999) 3.51

Results of surgical and nonsurgical treatment for small-sized hepatocellular carcinomas: a retrospective and nationwide survey in Japan. The Liver Cancer Study Group of Japan. Hepatology (2000) 3.42

Polypurine sequences within a downstream exon function as a splicing enhancer. Mol Cell Biol (1994) 3.15

High-resolution structure of the oligomerization domain of p53 by multidimensional NMR. Science (1994) 2.98

cDNA sequence of human transforming gene hst and identification of the coding sequence required for transforming activity. Proc Natl Acad Sci U S A (1987) 2.97

Binding of the Drosophila sex-lethal gene product to the alternative splice site of transformer primary transcript. Nature (1990) 2.95

Control of doublesex alternative splicing by transformer and transformer-2 in Drosophila. Science (1991) 2.87

Myeloscopy, with special reference to blood flow changes in the cauda equina during Lasègue's test. Int Orthop (1981) 2.82

Experimental investigation of geologically produced antineutrinos with KamLAND. Nature (2005) 2.75

Construction of a novel database containing aberrant splicing mutations of mammalian genes. Gene (1994) 2.68

Requirement of CD9 on the egg plasma membrane for fertilization. Science (2000) 2.65

Pathogenesis of Chiari malformation: a morphometric study of the posterior cranial fossa. J Neurosurg (1997) 2.60

Tumor angiogenesis in human lung adenocarcinoma. Cancer (1994) 2.59

Extracellular ATP or ADP induce chemotaxis of cultured microglia through Gi/o-coupled P2Y receptors. J Neurosci (2001) 2.54

Cloning and characterization of novel CIS family genes. Biochem Biophys Res Commun (1997) 2.51

No-mortality liver resection for hepatocellular carcinoma in cirrhotic and noncirrhotic patients: is there a way? A prospective analysis of our approach. Arch Surg (1999) 2.47

Quantitation of hepatitis B virus genomic DNA by real-time detection PCR. J Clin Microbiol (1999) 2.46

Organization and structure of an E. coli tRNA operon containing seven tRNA genes. Cell (1981) 2.45

Molecular cloning and characterization of a novel human G-protein-coupled receptor, EDG7, for lysophosphatidic acid. J Biol Chem (1999) 2.44

Interferon-alpha-mediated down-regulation of angiogenesis-related genes and therapy of bladder cancer are dependent on optimization of biological dose and schedule. Clin Cancer Res (1999) 2.39

Ultrasonically guided percutaneous microwave coagulation therapy for small hepatocellular carcinoma. Cancer (1994) 2.34

Genomic sequence of hst, a transforming gene encoding a protein homologous to fibroblast growth factors and the int-2-encoded protein. Proc Natl Acad Sci U S A (1987) 2.34

Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice. Clin Cancer Res (1999) 2.26

Downregulation of caffeic acid 3-O-methyltransferase and caffeoyl CoA 3-O-methyltransferase in transgenic alfalfa. impacts on lignin structure and implications for the biosynthesis of G and S lignin. Plant Cell (2001) 2.23

Miller-Dieker lissencephaly gene encodes a subunit of brain platelet-activating factor acetylhydrolase [corrected]. Nature (1994) 2.22

The gene for Machado-Joseph disease maps to human chromosome 14q. Nat Genet (1993) 2.18

Molecular cloning and nucleotide sequence of the cDNA for rat peroxisomal enoyl-CoA: hydratase-3-hydroxyacyl-CoA dehydrogenase bifunctional enzyme. J Biol Chem (1985) 2.12

Role of human cytochrome P4502A6 in C-oxidation of nicotine. Drug Metab Dispos (1996) 2.11

Phage-conversion of toxigenicity in Clostridium botulinum types C and D. Jpn J Med Sci Biol (1971) 2.09

Over-expression of facilitative glucose transporter genes in human cancer. Biochem Biophys Res Commun (1990) 2.06

Preferential excision of the 5' proximal intron from mRNA precursors with two introns as mediated by the cap structure. Proc Natl Acad Sci U S A (1987) 2.04

Ataxia with isolated vitamin E deficiency is caused by mutations in the alpha-tocopherol transfer protein. Nat Genet (1995) 2.03

Lysenin, a novel sphingomyelin-specific binding protein. J Biol Chem (1998) 2.02

Postmarketing surveillance of the safety profile of infliximab in 5000 Japanese patients with rheumatoid arthritis. Ann Rheum Dis (2007) 2.01

Autosomal dominant moyamoya disease maps to chromosome 17q25.3. Neurology (2008) 2.00

VCP/p97 in abnormal protein aggregates, cytoplasmic vacuoles, and cell death, phenotypes relevant to neurodegeneration. Cell Death Differ (2001) 2.00

Genetic alterations of the c-erbB-2 oncogene occur frequently in tubular adenocarcinoma of the stomach and are often accompanied by amplification of the v-erbA homologue. Oncogene (1988) 1.99

K-sam, an amplified gene in stomach cancer, is a member of the heparin-binding growth factor receptor genes. Proc Natl Acad Sci U S A (1990) 1.99

Conversion of toxigenicity in Clostridium botulinum type C. Jpn J Microbiol (1970) 1.98

Did ossification of the posterior longitudinal ligament of the spine evolve in the modern period? A paleopathologic study of ancient human skeletons in Japan. J Rheumatol (2000) 1.96

Binding of the Drosophila transformer and transformer-2 proteins to the regulatory elements of doublesex primary transcript for sex-specific RNA processing. Proc Natl Acad Sci U S A (1992) 1.94

Association of U6 snRNA with the 5'-splice site region of pre-mRNA in the spliceosome. Genes Dev (1992) 1.94

Fungal metabolites. Part 11. A potent immunosuppressive activity found in Isaria sinclairii metabolite. J Antibiot (Tokyo) (1994) 1.93

A unique vacuolar processing enzyme responsible for conversion of several proprotein precursors into the mature forms. FEBS Lett (1991) 1.92

Nucleotide sequences recognized by the AGAMOUS MADS domain of Arabidopsis thaliana in vitro. Plant J (1993) 1.91

A human RNA helicase-like protein, HRH1, facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome. Genes Dev (1996) 1.90

Dynamic imaging of pancreatic diseases by contrast enhanced coded phase inversion harmonic ultrasonography. Gut (2004) 1.89

New in vitro kinetic model for evaluating bactericidal efficacy of antibiotics. Antimicrob Agents Chemother (1980) 1.89

Bacteriophages of Clostridium botulinum. J Virol (1968) 1.88

Monoclonal antibodies to mouse complement receptor type 1 (CR1). Their use in a distribution study showing that mouse erythrocytes and platelets are CR1-negative. J Immunol (1988) 1.86

Cloning of the iron superoxide dismutase gene (sodB) in Escherichia coli K-12. J Bacteriol (1984) 1.86

Molecular composition of Clostridium botulinum type A progenitor toxins. Infect Immun (1996) 1.82

Biochemical identification of Xenopus Pumilio as a sequence-specific cyclin B1 mRNA-binding protein that physically interacts with a Nanos homolog, Xcat-2, and a cytoplasmic polyadenylation element-binding protein. J Biol Chem (2001) 1.81

Friedreich-like ataxia with retinitis pigmentosa caused by the His101Gln mutation of the alpha-tocopherol transfer protein gene. Ann Neurol (1997) 1.81

Redistribution of phosphatidylethanolamine at the cleavage furrow of dividing cells during cytokinesis. Proc Natl Acad Sci U S A (1996) 1.81

Balanced biosynthesis of major membrane components through regulated degradation of the committed enzyme of lipid A biosynthesis by the AAA protease FtsH (HflB) in Escherichia coli. Mol Microbiol (1999) 1.80

Temperature sensitive mutants of Escherichia coli for tRNA synthesis. Nucleic Acids Res (1974) 1.79

Identification of a putative RNA helicase (HRH1), a human homolog of yeast Prp22. Mol Cell Biol (1994) 1.78

Adult-onset spinocerebellar dysfunction caused by a mutation in the gene for the alpha-tocopherol-transfer protein. N Engl J Med (1995) 1.77

A nuclear cap binding protein from HeLa cells. Nucleic Acids Res (1990) 1.77

Two different RNA binding activities for the AU-rich element and the poly(A) sequence of the mouse neuronal protein mHuC. Nucleic Acids Res (1996) 1.77

Affinity for alpha-tocopherol transfer protein as a determinant of the biological activities of vitamin E analogs. FEBS Lett (1997) 1.74

Characterization of CYP2A6 involved in 3'-hydroxylation of cotinine in human liver microsomes. J Pharmacol Exp Ther (1996) 1.74

Accurate preoperative evaluation of liver mass lesions without fine-needle biopsy. Hepatology (1999) 1.73

Possible link between large artery stiffness and coronary flow velocity reserve. Heart (2007) 1.72

Molecular mechanisms of Spemann's organizer formation: conserved growth factor synergy between Xenopus and mouse. Genes Dev (1995) 1.71

Transforming gene from human stomach cancers and a noncancerous portion of stomach mucosa. Proc Natl Acad Sci U S A (1986) 1.71

Modulation of transforming growth factor beta function in hepatocytes and hepatic stellate cells in rat liver injury. Gut (2000) 1.70

[Studies on the immune bacteriolysis. XIV. Requirement of all nine components of complement for immune bacteriolysis]. Biken J (1968) 1.70

Peripheral administration of nesfatin-1 reduces food intake in mice: the leptin-independent mechanism. Endocrinology (2008) 1.69

Percutaneous microwave coagulation therapy for solitary metastatic liver tumors from colorectal cancer: a pilot clinical study. Am J Gastroenterol (1999) 1.69

Stratificational relationship among the main nerves from the dorsal division of the sacral plexus and the innervation of the piriformis. Anat Rec (1992) 1.69

Control of Drosophila Sex-lethal pre-mRNA splicing by its own female-specific product. Nucleic Acids Res (1992) 1.68

Scavenger receptor-mediated uptake and metabolism of lipid vesicles containing acidic phospholipids by mouse peritoneal macrophages. J Biol Chem (1990) 1.67

Expression of MUC1 and MUC2 mucins in gastric carcinomas: its relationship with the prognosis of the patients. Clin Cancer Res (1998) 1.66

Phosphorylation of serine 392 stabilizes the tetramer formation of tumor suppressor protein p53. Biochemistry (1997) 1.66

Effect of the cap structure on pre-mRNA splicing in Xenopus oocyte nuclei. Genes Dev (1989) 1.66