Published in J Urol on March 19, 2010
c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype. Proc Natl Acad Sci U S A (2011) 1.75
Targeting the osteosarcoma cancer stem cell. J Orthop Surg Res (2010) 1.52
Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer. Nucleic Acids Res (2012) 1.40
Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics. Int J Cancer (2011) 1.27
The dietary bioflavonoid quercetin synergizes with epigallocathechin gallate (EGCG) to inhibit prostate cancer stem cell characteristics, invasion, migration and epithelial-mesenchymal transition. J Mol Signal (2010) 1.26
Steroidogenic enzymes and stem cell markers are upregulated during androgen deprivation in prostate cancer. Mol Med (2011) 1.24
Tumorigenicity of pluripotent stem cells: biological insights from molecular imaging. J R Soc Interface (2010) 1.16
Frequent gene products and molecular pathways altered in prostate cancer- and metastasis-initiating cells and their progenies and novel promising multitargeted therapies. Mol Med (2011) 1.13
Epithelial cell adhesion molecule regulates tumor initiation and tumorigenesis via activating reprogramming factors and epithelial-mesenchymal transition gene expression in colon cancer. J Biol Chem (2012) 1.10
E-cadherin plasticity in prostate cancer stem cell invasion. Am J Cancer Res (2010) 1.10
Prolonged androgen deprivation leads to downregulation of androgen receptor and prostate-specific membrane antigen in prostate cancer cells. Int J Oncol (2012) 1.06
Pathobiological implications of the expression of EGFR, pAkt, NF-κB and MIC-1 in prostate cancer stem cells and their progenies. PLoS One (2012) 1.06
Prostate cancer cell lines under hypoxia exhibit greater stem-like properties. PLoS One (2011) 1.05
TLR9 signaling through NF-κB/RELA and STAT3 promotes tumor-propagating potential of prostate cancer cells. Oncotarget (2015) 0.98
The role of epithelial plasticity in prostate cancer dissemination and treatment resistance. Cancer Metastasis Rev (2014) 0.94
Expression of the stem cell marker, Nanog, in human endometrial adenocarcinoma. Int J Gynecol Pathol (2011) 0.93
Cell-based selection provides novel molecular probes for cancer stem cells. Int J Cancer (2013) 0.91
Cancer stem cell subsets and their relationships. J Transl Med (2011) 0.89
Synergistic effect of SCF and G-CSF on stem-like properties in prostate cancer cell lines. Tumour Biol (2012) 0.88
Salinomycin induces cell death and differentiation in head and neck squamous cell carcinoma stem cells despite activation of epithelial-mesenchymal transition and Akt. BMC Cancer (2012) 0.88
Expression of stemness genes in primary breast cancer tissues: the role of SOX2 as a prognostic marker for detection of early recurrence. Oncotarget (2014) 0.87
Hypoxia, stem cells and bone tumor. Cancer Lett (2011) 0.86
Induced pluripotent stem cell-related genes influence biological behavior and 5-fluorouracil sensitivity of colorectal cancer cells. J Zhejiang Univ Sci B (2012) 0.85
Cell-to-cell signaling influences the fate of prostate cancer stem cells and their potential to generate more aggressive tumors. PLoS One (2012) 0.85
Induced pluripotent cancer cells: progress and application. J Cancer Res Clin Oncol (2010) 0.85
Human α(2)β(1)(HI) CD133(+VE) epithelial prostate stem cells express low levels of active androgen receptor. PLoS One (2012) 0.85
SOX2 expression in the developing, adult, as well as, diseased prostate. Prostate Cancer Prostatic Dis (2014) 0.83
Stem cell pathologies and neurological disease. Mod Pathol (2011) 0.82
Animal models relevant to human prostate carcinogenesis underlining the critical implication of prostatic stem/progenitor cells. Biochim Biophys Acta (2011) 0.81
Modulation of the tumor vasculature and oxygenation to improve therapy. Pharmacol Ther (2015) 0.80
The role of SOX2 in small cell lung cancer, lung adenocarcinoma and squamous cell carcinoma of the lung. Transl Lung Cancer Res (2013) 0.78
Cellular Plasticity in Prostate Cancer Bone Metastasis. Prostate Cancer (2015) 0.78
Role of SOX2 in the etiology of embryonal carcinoma, based on analysis of the NCCIT and NT2 cell lines. PLoS One (2014) 0.77
Stem cells in genetically-engineered mouse models of prostate cancer. Endocr Relat Cancer (2015) 0.77
Hypoxia regulates SOX2 expression to promote prostate cancer cell invasion and sphere formation. Am J Cancer Res (2016) 0.77
E-Cadherin repression increases amount of cancer stem cells in human A549 lung adenocarcinoma and stimulates tumor growth. Cell Cycle (2016) 0.77
The crossroads between cancer stem cells and aging. BMC Cancer (2015) 0.76
Pyruvate dehydrogenase expression is negatively associated with cell stemness and worse clinical outcome in prostate cancers. Oncotarget (2017) 0.75
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Prostate Cancer Stem Cell Markers Drive Progression, Therapeutic Resistance, and Bone Metastasis. Stem Cells Int (2017) 0.75
Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell (2007) 101.42
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An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat Genet (2008) 17.67
Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res (2005) 13.89
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Module map of stem cell genes guides creation of epithelial cancer stem cells. Cell Stem Cell (2008) 7.69
Prostate cancer. N Engl J Med (2003) 5.91
Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells. Oncogene (2006) 5.86
The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations. Proc Natl Acad Sci U S A (2008) 3.13
Mesenchymal-to-epithelial transition facilitates bladder cancer metastasis: role of fibroblast growth factor receptor-2. Cancer Res (2006) 3.12
Hierarchical organization of prostate cancer cells in xenograft tumors: the CD44+alpha2beta1+ cell population is enriched in tumor-initiating cells. Cancer Res (2007) 3.00
CD44+ CD24(-) prostate cells are early cancer progenitor/stem cells that provide a model for patients with poor prognosis. Br J Cancer (2008) 2.58
Expression of the cellular adhesion molecule E-cadherin is reduced or absent in high-grade prostate cancer. Cancer Res (1992) 2.55
PC3 human prostate carcinoma cell holoclones contain self-renewing tumor-initiating cells. Cancer Res (2008) 2.16
Retention of intrinsic stem cell hierarchies in carcinoma-derived cell lines. Cancer Res (2005) 2.12
Epithelial-mesenchymal transition events during human embryonic stem cell differentiation. Cancer Res (2007) 2.10
Reduction of E-cadherin levels and deletion of the alpha-catenin gene in human prostate cancer cells. Cancer Res (1993) 1.96
Co-culturing human prostate carcinoma cells with hepatocytes leads to increased expression of E-cadherin. Br J Cancer (2007) 1.75
E-cadherin expression in prostate cancer: a broad survey using high-density tissue microarray technology. Hum Pathol (2001) 1.68
Prostate epithelial cell lines form spheroids with evidence of glandular differentiation in three-dimensional Matrigel cultures. Br J Cancer (2001) 1.38
Pten, tumorigenesis, and stem cell self-renewal. Cell (2006) 1.36
Chromosome 5 suppresses tumorigenicity of PC3 prostate cancer cells: correlation with re-expression of alpha-catenin and restoration of E-cadherin function. Cancer Res (1995) 1.28
Overexpression of E-cadherin and beta-catenin proteins in metastatic prostate cancer cells in bone. Prostate (2008) 1.19
Anchorage-independent culture maintains prostate stem cells. Dev Biol (2007) 1.15
Prostate stem cells and prostate cancer. Cold Spring Harb Symp Quant Biol (2005) 1.05
alpha-Catenin overrides Src-dependent activation of beta-catenin oncogenic signaling. Mol Cancer Ther (2008) 0.97
Association of E-cadherin germ-line alterations with prostate cancer. Clin Cancer Res (2001) 0.85
A PCR/restriction digestion assay for the detection of the transcript variants 1 and 2 of POU5F1. Genes Chromosomes Cancer (2008) 0.84
Lack of evidence for the association of E-cadherin gene polymorphism with increased risk or progression of prostate cancer. Urol Int (2004) 0.83
agriGO: a GO analysis toolkit for the agricultural community. Nucleic Acids Res (2010) 10.53
Screening for prostate cancer: systematic review and meta-analysis of randomised controlled trials. BMJ (2010) 7.15
Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro. Glia (2002) 5.81
Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells. J Clin Invest (2005) 5.30
EasyGO: Gene Ontology-based annotation and functional enrichment analysis tool for agronomical species. BMC Genomics (2007) 3.07
Integrative genomic analyses reveal clinically relevant long noncoding RNAs in human cancer. Nat Struct Mol Biol (2013) 2.84
Stem-like cells in bone sarcomas: implications for tumorigenesis. Neoplasia (2005) 2.62
Immunological and clinical responses in metastatic renal cancer patients vaccinated with tumor RNA-transfected dendritic cells. Cancer Res (2003) 2.62
Aldehyde dehydrogenase-expressing colon stem cells contribute to tumorigenesis in the transition from colitis to cancer. Cancer Res (2009) 2.40
Reversal of myeloid cell-mediated immunosuppression in patients with metastatic renal cell carcinoma. Clin Cancer Res (2008) 2.26
Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis. Plant Physiol (2008) 2.25
Pivotal Advance: Tumor-mediated induction of myeloid-derived suppressor cells and M2-polarized macrophages by altering intracellular PGE₂ catabolism in myeloid cells. J Leukoc Biol (2010) 2.22
A critical assessment of the quality of reporting of randomized, controlled trials in the urology literature. J Urol (2007) 2.16
Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors. J Clin Invest (2002) 2.09
Phenotypic and functional characterization of adult brain neuropoiesis. Proc Natl Acad Sci U S A (2005) 2.08
Neural stem cell heterogeneity demonstrated by molecular phenotyping of clonal neurospheres. Proc Natl Acad Sci U S A (2002) 2.04
Embryonic stem cells proliferate and differentiate when seeded into kidney scaffolds. J Am Soc Nephrol (2009) 2.03
Microglia instruct subventricular zone neurogenesis. Glia (2006) 2.02
DWARF27, an iron-containing protein required for the biosynthesis of strigolactones, regulates rice tiller bud outgrowth. Plant Cell (2009) 2.00
Pathophysiologic effects of vascular-targeting agents and the implications for combination with conventional therapies. Cancer Res (2006) 2.00
PMRD: plant microRNA database. Nucleic Acids Res (2009) 1.94
Telomerase mRNA-transfected dendritic cells stimulate antigen-specific CD8+ and CD4+ T cell responses in patients with metastatic prostate cancer. J Immunol (2005) 1.82
Mesenchymal stem cells spontaneously express neural proteins in culture and are neurogenic after transplantation. Stem Cells (2005) 1.73
Oncologic doses of zoledronic acid induce osteonecrosis of the jaw-like lesions in rice rats (Oryzomys palustris) with periodontitis. J Bone Miner Res (2012) 1.73
Cancer immunotherapy with mRNA-transfected dendritic cells. Immunol Rev (2004) 1.66
GM1-ganglioside-mediated activation of the unfolded protein response causes neuronal death in a neurodegenerative gangliosidosis. Mol Cell (2004) 1.64
Analyzing circadian expression data by harmonic regression based on autoregressive spectral estimation. Bioinformatics (2010) 1.63
Oxidative stress regulates expression of VEGFR1 in myeloid cells: link to tumor-induced immune suppression in renal cell carcinoma. J Immunol (2008) 1.63
Leukemia regression by vascular disruption and antiangiogenic therapy. Blood (2010) 1.60
SALL4 is a novel sensitive and specific marker for metastatic germ cell tumors, with particular utility in detection of metastatic yolk sac tumors. Cancer (2009) 1.59
The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance. EMBO Mol Med (2013) 1.59
Persistent exposure to Mycoplasma induces malignant transformation of human prostate cells. PLoS One (2009) 1.57
Clinical pharmacogenetics implementation: approaches, successes, and challenges. Am J Med Genet C Semin Med Genet (2014) 1.57
Zinc transporter ZIP8 (SLC39A8) and zinc influence IFN-gamma expression in activated human T cells. J Leukoc Biol (2009) 1.50
Adipose tissue-derived mesenchymal stem cell-based liver gene delivery. J Hepatol (2010) 1.50
Evaluating the evidence: statistical methods in randomized controlled trials in the urological literature. J Urol (2008) 1.48
Expression of an exogenous human Oct-4 promoter identifies tumor-initiating cells in osteosarcoma. Cancer Res (2009) 1.46
The magnesium-chelatase H subunit binds abscisic acid and functions in abscisic acid signaling: new evidence in Arabidopsis. Plant Physiol (2009) 1.44
Factors associated with the full publication of studies presented in abstract form at the annual meeting of the American Urological Association. J Urol (2007) 1.40
SALL4 is a novel diagnostic marker for testicular germ cell tumors. Am J Surg Pathol (2009) 1.39
Bone marrow transdifferentiation in brain after transplantation: a retrospective study. Lancet (2004) 1.38
Diagnostic utility of SALL4 in extragonadal yolk sac tumors: an immunohistochemical study of 59 cases with comparison to placental-like alkaline phosphatase, alpha-fetoprotein, and glypican-3. Am J Surg Pathol (2009) 1.37
Comparison of the EF-1 alpha and the CMV promoter for engineering stable tumor cell lines using recombinant adeno-associated virus. Anticancer Res (2003) 1.35
Genome-scale analysis and comparison of gene expression profiles in developing and germinated pollen in Oryza sativa. BMC Genomics (2010) 1.35
PlantGSEA: a gene set enrichment analysis toolkit for plant community. Nucleic Acids Res (2013) 1.35
Tumor-associated macrophages mediate immunosuppression in the renal cancer microenvironment by activating the 15-lipoxygenase-2 pathway. Cancer Res (2011) 1.34
Annotation and expression profile analysis of 2073 full-length cDNAs from stress-induced maize (Zea mays L.) seedlings. Plant J (2006) 1.31
Regulated expression of ATF5 is required for the progression of neural progenitor cells to neurons. J Neurosci (2003) 1.31
Trifecta nerve complex: potential anatomical basis for microsurgical denervation of the spermatic cord for chronic orchialgia. J Urol (2013) 1.28
Circulating and tumor-infiltrating myeloid cell subsets in patients with bladder cancer. Int J Cancer (2011) 1.27
SALL4 is a novel sensitive and specific marker of ovarian primitive germ cell tumors and is particularly useful in distinguishing yolk sac tumor from clear cell carcinoma. Am J Surg Pathol (2009) 1.23
Synergy between tumor immunotherapy and antiangiogenic therapy. Blood (2003) 1.23
Injection of immature dendritic cells into adjuvant-treated skin obviates the need for ex vivo maturation. J Immunol (2003) 1.22
Effect of the second-generation vascular disrupting agent OXi4503 on tumor vascularity. Clin Cancer Res (2006) 1.22
Chondroitin sulfate proteoglycans potently inhibit invasion and serve as a central organizer of the brain tumor microenvironment. J Neurosci (2013) 1.20
Temporally restricted substrate interactions direct fate and specification of neural precursors derived from embryonic stem cells. Proc Natl Acad Sci U S A (2006) 1.20
Current development status of small-molecule vascular disrupting agents. Curr Opin Investig Drugs (2006) 1.18
PCR inhibition by reverse transcriptase leads to an overestimation of amplification efficiency. Nucleic Acids Res (2005) 1.18
CD44+/CD24- ovarian cancer cells demonstrate cancer stem cell properties and correlate to survival. Clin Exp Metastasis (2012) 1.18
Bone marrow stem and progenitor cell contribution to neovasculogenesis is dependent on model system with SDF-1 as a permissive trigger. Blood (2009) 1.15
RNA aptamer-targeted inhibition of NF-kappa B suppresses non-small cell lung cancer resistance to doxorubicin. Mol Ther (2007) 1.14
DNA methylation is required for silencing of ant4, an adenine nucleotide translocase selectively expressed in mouse embryonic stem cells and germ cells. Stem Cells (2005) 1.14
Reversal of tumor-mediated immunosuppression. Clin Cancer Res (2007) 1.13
Residual tumor cells are unique cellular targets in glioblastoma. Ann Neurol (2010) 1.13
Connective tissue growth factor with a novel fibronectin binding site promotes cell adhesion and migration during rat oval cell activation. Hepatology (2008) 1.12
LSPR: an integrated periodicity detection algorithm for unevenly sampled temporal microarray data. Bioinformatics (2011) 1.12
Evolutionarily conserved mammalian adenine nucleotide translocase 4 is essential for spermatogenesis. J Biol Chem (2007) 1.11
Purification of immature neuronal cells from neural stem cell progeny. PLoS One (2011) 1.11
Diagnostic utility of novel stem cell markers SALL4, OCT4, NANOG, SOX2, UTF1, and TCL1 in primary mediastinal germ cell tumors. Am J Surg Pathol (2010) 1.10
A novel DNMT3B splice variant expressed in tumor and pluripotent cells modulates genomic DNA methylation patterns and displays altered DNA binding. Mol Cancer Res (2009) 1.10
Smoothelin immunohistochemistry is a useful adjunct for assessing muscularis propria invasion in bladder carcinoma. Histopathology (2010) 1.10
E-cadherin plasticity in prostate cancer stem cell invasion. Am J Cancer Res (2010) 1.10
Primary renal carcinoid tumors: clinicopathologic features of 9 cases with emphasis on novel immunohistochemical findings. Hum Pathol (2011) 1.09
H1 RNA polymerase III promoter-driven expression of an RNA aptamer leads to high-level inhibition of intracellular protein activity. Nucleic Acids Res (2006) 1.09
BMS-777607, a small-molecule met kinase inhibitor, suppresses hepatocyte growth factor-stimulated prostate cancer metastatic phenotype in vitro. Mol Cancer Ther (2010) 1.08
Low proliferation and differentiation capacities of adult hippocampal stem cells correlate with memory dysfunction in humans. Brain (2010) 1.07
Altered expression of 15-hydroxyprostaglandin dehydrogenase in tumor-infiltrated CD11b myeloid cells: a mechanism for immune evasion in cancer. J Immunol (2009) 1.07
Web-based synoptic reporting for cancer checklists. J Pathol Inform (2011) 1.07
RNA-binding protein LIN28 is a marker for testicular germ cell tumors. Hum Pathol (2011) 1.07
Enhancing the immunostimulatory function of dendritic cells by transfection with mRNA encoding OX40 ligand. Blood (2004) 1.06
Arabidopsis Hormone Database: a comprehensive genetic and phenotypic information database for plant hormone research in Arabidopsis. Nucleic Acids Res (2008) 1.05
Derivation and large-scale expansion of multipotent astroglial neural progenitors from adult human brain. Development (2006) 1.04
plantsUPS: a database of plants' Ubiquitin Proteasome System. BMC Genomics (2009) 1.04
Identification of a drought tolerant introgression line derived from Dongxiang common wild rice (O. rufipogon Griff.). Plant Mol Biol (2006) 1.04
Impact of hypoxia on the metastatic potential of human prostate cancer cells. Int J Radiat Oncol Biol Phys (2011) 1.04
Anticancer effects of niclosamide in human glioblastoma. Clin Cancer Res (2013) 1.03
Modulation of blood flow, hypoxia, and vascular function in orthotopic prostate tumors during exercise. J Natl Cancer Inst (2014) 1.02
Differentiation of human embryonic stem cells into immunostimulatory dendritic cells under feeder-free culture conditions. Clin Cancer Res (2008) 1.02