Published in Cancer Res on July 15, 2007
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Targeting the unique methylation pattern of androgen receptor (AR) promoter in prostate stem/progenitor cells with 5-aza-2'-deoxycytidine (5-AZA) leads to suppressed prostate tumorigenesis. J Biol Chem (2012) 0.98
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Marked improvement of cytotoxic effects induced by docetaxel on highly metastatic and androgen-independent prostate cancer cells by downregulating macrophage inhibitory cytokine-1. Br J Cancer (2013) 0.87
Sulforaphane and TRAIL induce a synergistic elimination of advanced prostate cancer stem-like cells. Int J Oncol (2014) 0.87
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Enrichment of human prostate cancer cells with tumor initiating properties in mouse and zebrafish xenografts by differential adhesion. Prostate (2013) 0.86
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Novel interaction between proliferating cell nuclear antigen and HLA I on the surface of tumor cells inhibits NK cell function through NKp44. PLoS One (2013) 0.84
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Human prostate cancer initiating cells isolated directly from localized cancer do not form prostaspheres in primary culture. Prostate (2012) 0.82
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A novel in vitro assay of tumor-initiating cells in xenograft prostate tumors. Prostate (2010) 0.80
Aquaporin 3 promotes the stem-like properties of gastric cancer cells via Wnt/GSK-3β/β-catenin pathway. Oncotarget (2016) 0.80
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Defining a Population of Stem-like Human Prostate Cancer Cells That Can Generate and Propagate Castration-Resistant Prostate Cancer. Clin Cancer Res (2016) 0.79
miR-199a-3p targets stemness-related and mitogenic signaling pathways to suppress the expansion and tumorigenic capabilities of prostate cancer stem cells. Oncotarget (2016) 0.79
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GLI1 confers profound phenotypic changes upon LNCaP prostate cancer cells that include the acquisition of a hormone independent state. PLoS One (2011) 0.78
A patient tumor-derived orthotopic xenograft mouse model replicating the group 3 supratentorial primitive neuroectodermal tumor in children. Neuro Oncol (2014) 0.78
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Prostate tumor cells with cancer progenitor properties have high telomerase activity and are rapidly killed by telomerase interference. Prostate (2011) 0.78
Hypoxia regulates SOX2 expression to promote prostate cancer cell invasion and sphere formation. Am J Cancer Res (2016) 0.77
Registered report: the microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Elife (2015) 0.77
Expansion of prostate epithelial progenitor cells after inflammation of the mouse prostate. Am J Physiol Renal Physiol (2015) 0.77
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat Med (2011) 6.85
Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic. Cancer Res (2005) 5.87
The PSA(-/lo) prostate cancer cell population harbors self-renewing long-term tumor-propagating cells that resist castration. Cell Stem Cell (2012) 2.69
Functional evidence that the self-renewal gene NANOG regulates human tumor development. Stem Cells (2009) 2.59
PC3 human prostate carcinoma cell holoclones contain self-renewing tumor-initiating cells. Cancer Res (2008) 2.16
MicroRNA regulation of cancer stem cells. Cancer Res (2011) 1.84
Prostate cancer stem/progenitor cells: identification, characterization, and implications. Mol Carcinog (2007) 1.74
Intracellular nucleotides act as critical prosurvival factors by binding to cytochrome C and inhibiting apoptosome. Cell (2006) 1.61
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Distinct microRNA expression profiles in prostate cancer stem/progenitor cells and tumor-suppressive functions of let-7. Cancer Res (2012) 1.55
Annexin II expression is reduced or lost in prostate cancer cells and its re-expression inhibits prostate cancer cell migration. Oncogene (2003) 1.46
Association of active caspase 8 with the mitochondrial membrane during apoptosis: potential roles in cleaving BAP31 and caspase 3 and mediating mitochondrion-endoplasmic reticulum cross talk in etoposide-induced cell death. Mol Cell Biol (2004) 1.46
Bax-dependent regulation of Bak by voltage-dependent anion channel 2. J Biol Chem (2005) 1.32
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Critical and distinct roles of p16 and telomerase in regulating the proliferative life span of normal human prostate epithelial progenitor cells. J Biol Chem (2008) 1.23
Cancer stem cells and radioresistance. Int J Radiat Biol (2014) 1.20
Identification and characterization of Bimgamma, a novel proapoptotic BH3-only splice variant of Bim. Cancer Res (2002) 1.20
Subcellular localization and tumor-suppressive functions of 15-lipoxygenase 2 (15-LOX2) and its splice variants. J Biol Chem (2003) 1.18
Methodologies in assaying prostate cancer stem cells. Methods Mol Biol (2009) 1.16
Evidence that arachidonate 15-lipoxygenase 2 is a negative cell cycle regulator in normal prostate epithelial cells. J Biol Chem (2002) 1.15
Functional remodeling of benign human prostatic tissues in vivo by spontaneously immortalized progenitor and intermediate cells. Stem Cells (2010) 1.09
CD44-positive cancer stem cells expressing cellular prion protein contribute to metastatic capacity in colorectal cancer. Cancer Res (2013) 1.05
New insights into prostate cancer stem cells. Cell Cycle (2013) 1.02
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Cell-autonomous induction of functional tumor suppressor 15-lipoxygenase 2 (15-LOX2) contributes to replicative senescence of human prostate progenitor cells. Oncogene (2005) 0.97
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Bim, a proapoptotic protein, up-regulated via transcription factor E2F1-dependent mechanism, functions as a prosurvival molecule in cancer. J Biol Chem (2012) 0.91
Evidence that senescent human prostate epithelial cells enhance tumorigenicity: cell fusion as a potential mechanism and inhibition by p16INK4a and hTERT. Int J Cancer (2008) 0.91
In vivo functional studies of tumor-specific retrogene NanogP8 in transgenic animals. Cell Cycle (2013) 0.89
Drug-tolerant cancer cells show reduced tumor-initiating capacity: depletion of CD44 cells and evidence for epigenetic mechanisms. PLoS One (2011) 0.88
Defective molecular timer in the absence of nucleotides leads to inefficient caspase activation. PLoS One (2011) 0.84
An old player on a new playground: bmi-1 as a regulator of prostate stem cells. Cell Stem Cell (2010) 0.82
Activated ERM protein plays a critical role in drug resistance of MOLT4 cells induced by CCL25. PLoS One (2013) 0.81
Dissociated primary human prostate cancer cells coinjected with the immortalized Hs5 bone marrow stromal cells generate undifferentiated tumors in NOD/SCID-γ mice. PLoS One (2013) 0.80
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