Published in Transplantation on May 01, 1991
Minocycline and N-methyl-4-isoleucine cyclosporin (NIM811) mitigate storage/reperfusion injury after rat liver transplantation through suppression of the mitochondrial permeability transition. Hepatology (2008) 2.22
Inhibition of TNF-α protects against hepatic ischemia-reperfusion injury in rats via NF-κB dependent pathway. Naunyn Schmiedebergs Arch Pharmacol (2012) 1.09
Signs of reperfusion injury following CO2 pneumoperitoneum: an in vivo microscopy study. Surg Endosc (2007) 1.08
Intravenous administration of glutathione protects parenchymal and non-parenchymal liver cells against reperfusion injury following rat liver transplantation. World J Gastroenterol (2004) 1.00
Ischemic preconditioning decreases C-X-C chemokine expression and neutrophil accumulation early after liver transplantation in rats. World J Gastroenterol (2003) 0.91
C-Jun N-terminal kinase 2 promotes graft injury via the mitochondrial permeability transition after mouse liver transplantation. Am J Transplant (2008) 0.90
Pentoxifylline inhibits liver expression of tumor necrosis factor alpha mRNA following normothermic ischemia-reperfusion. HPB (Oxford) (2007) 0.83
Rapid conversion to high xanthine oxidase activity in viable Kupffer cells during hypoxia. J Clin Invest (1994) 0.83
Ischemia reperfusion-facilitated sinusoidal endothelial cell injury in liver transplantation and the resulting impact of extravasated platelet aggregation. Eur Surg (2015) 0.76
Icam-1 upregulation in ethanol-induced Fatty murine livers promotes injury and sinusoidal leukocyte adherence after transplantation. HPB Surg (2012) 0.76
Downregulation of cytokine release by heat preconditioning of livers used for transplantation in rats. Dig Dis Sci (2005) 0.75
Endothelin-1 levels in portal venous blood in relation to hepatic tissue microcirculation disturbance and hepatic cell injury after ischemia/reperfusion. Surg Today (1997) 0.75
Measurements of tissue viability in transplantation. Philos Trans R Soc Lond B Biol Sci (1997) 0.75
Ischemic preconditioning modulates ROS to confer protection in liver ischemia and reperfusion. EXCLI J (2017) 0.75
mir-29 regulates Mcl-1 protein expression and apoptosis. Oncogene (2007) 7.02
Biliary tract cancers. N Engl J Med (1999) 6.36
The mitochondrial permeability transition initiates autophagy in rat hepatocytes. FASEB J (2001) 4.99
Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c. J Clin Invest (2000) 3.58
Essential role of tumor necrosis factor alpha in alcohol-induced liver injury in mice. Gastroenterology (1999) 3.24
Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties. Biochim Biophys Acta (1986) 3.12
Hepatic microsomal ethanol oxidation. Hydrogen peroxide formation and the role of catalase. Eur J Biochem (1972) 3.11
Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice. Hepatology (2001) 2.72
NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease. J Clin Invest (2000) 2.67
Antibiotics prevent liver injury in rats following long-term exposure to ethanol. Gastroenterology (1995) 2.58
Hepatocyte apoptosis after bile duct ligation in the mouse involves Fas. Gastroenterology (1999) 2.56
Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism. Cancer Res (2000) 2.38
Inactivation of Kupffer cells prevents early alcohol-induced liver injury. Hepatology (1994) 2.37
Antibodies to tumor necrosis factor alfa attenuate hepatic necrosis and inflammation caused by chronic exposure to ethanol in the rat. Hepatology (1997) 2.35
The role of proteases during apoptosis. FASEB J (1996) 2.35
Apoptosis: a mechanism of acute and chronic liver injury. Gut (2005) 2.33
Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas. J Clin Invest (1999) 2.32
The utility of CA 19-9 in the diagnoses of cholangiocarcinoma in patients without primary sclerosing cholangitis. Am J Gastroenterol (2000) 2.25
Cell death by apoptosis: basic concepts and disease relevance for the gastroenterologist. Gastroenterology (1996) 2.23
Prolonged disease-free survival after orthotopic liver transplantation plus adjuvant chemoirradiation for cholangiocarcinoma. Liver Transpl (2000) 2.23
Inhibition of interleukin 6-mediated mitogen-activated protein kinase activation attenuates growth of a cholangiocarcinoma cell line. Hepatology (1999) 2.20
Blebbing, free Ca2+ and mitochondrial membrane potential preceding cell death in hepatocytes. Nature (1987) 2.18
Reperfusion after liver transplantation in rats differentially activates the mitogen-activated protein kinases. Hepatology (1997) 2.14
Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to t-butylhydroperoxide. Biochem J (1995) 1.98
Evidence that hypoxia markers detect oxygen gradients in liver: pimonidazole and retrograde perfusion of rat liver. Br J Cancer (1995) 1.96
Hepatocyte apoptosis is a pathologic feature of human alcoholic hepatitis. J Hepatol (2001) 1.93
Electrical properties and conduction in reperfused papillary muscle. Circ Res (2001) 1.91
Assessment of Fura-2 for measurements of cytosolic free calcium. Cell Calcium (1990) 1.88
Selective loading of Rhod 2 into mitochondria shows mitochondrial Ca2+ transients during the contractile cycle in adult rabbit cardiac myocytes. Biochem Biophys Res Commun (1997) 1.86
Molecular cloning and characterization of a human mitochondrial ceramidase. J Biol Chem (2000) 1.76
Metabolic effects of ethanol in perfused rat liver. J Biol Chem (1969) 1.73
Flavin and pyridine nucleotide oxidation-reduction changes in perfused rat liver. I. Anoxia and subcellular localization of fluorescent flavoproteins. J Biol Chem (1969) 1.73
Primary cirrhotic hepatocytes resist TGFbeta-induced apoptosis through a ROS-dependent mechanism. J Hepatol (2004) 1.72
Distribution of electrical potential, pH, free Ca2+, and volume inside cultured adult rabbit cardiac myocytes during chemical hypoxia: a multiparameter digitized confocal microscopic study. Biophys J (1994) 1.70
The role of Kupffer cell oxidant production in early ethanol-induced liver disease. Free Radic Biol Med (2001) 1.69
Overexpression of the TGFbeta-regulated zinc finger encoding gene, TIEG, induces apoptosis in pancreatic epithelial cells. J Clin Invest (1997) 1.67
Reductive metabolism of the hypoxia marker pimonidazole is regulated by oxygen tension independent of the pyridine nucleotide redox state. Eur J Biochem (1998) 1.67
Oxidative phosphorylation and ultrastructural transformation in mitochondria in the intact ascites tumor cell. J Cell Biol (1971) 1.66
The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release. Mol Cell Biol (1998) 1.66
Attenuation of CCl(4)-induced hepatic fibrosis by GdCl(3) treatment or dietary glycine. Am J Physiol Gastrointest Liver Physiol (2001) 1.64
Reperfusion injury after liver preservation for transplantation. Annu Rev Pharmacol Toxicol (1997) 1.63
[Time intervals during and after emergency room treatment. An analysis using the trauma register of the German Society for Trauma Surgery]. Unfallchirurg (2010) 1.62
Ursodeoxycholic acid or clofibrate in the treatment of non-alcohol-induced steatohepatitis: a pilot study. Hepatology (1996) 1.62
Mitochondrial permeability transition in hepatocytes induced by t-BuOOH: NAD(P)H and reactive oxygen species. Am J Physiol (1997) 1.61
Ischemic preconditioning of rat livers against cold storage-reperfusion injury: role of nonparenchymal cells and the phenomenon of heterologous preconditioning. Liver Transpl (2001) 1.59
Nephrotoxic effects of primary immunosuppression with FK-506 and cyclosporine regimens after liver transplantation. Mayo Clin Proc (1994) 1.59
Mitochondrial permeability transition in pH-dependent reperfusion injury to rat hepatocytes. Am J Physiol (1997) 1.58
Alcohol causes both tolerance and sensitization of rat Kupffer cells via mechanisms dependent on endotoxin. Gastroenterology (1998) 1.58
Liposome-mitochondrial inner membrane fusion. Lateral diffusion of integral electron transfer components. J Biol Chem (1980) 1.56
Apoptosis of sinusoidal endothelial cells occurs during liver preservation injury by a caspase-dependent mechanism. Transplantation (1999) 1.56
The many facets of reperfusion injury. Gastroenterology (1995) 1.53
Intracellular pH during "chemical hypoxia" in cultured rat hepatocytes. Protection by intracellular acidosis against the onset of cell death. J Clin Invest (1989) 1.53
Nitric oxide in gastrointestinal epithelial cell carcinogenesis: linking inflammation to oncogenesis. Am J Physiol Gastrointest Liver Physiol (2001) 1.52
Bile salts mediate hepatocyte apoptosis by increasing cell surface trafficking of Fas. Am J Physiol Gastrointest Liver Physiol (2000) 1.51
Reduced early alcohol-induced liver injury in CD14-deficient mice. J Immunol (2001) 1.50
Drug-induced liver injury: mechanisms and test systems. Hepatology (2001) 1.49
Mitochondria as a source of reactive oxygen species during reductive stress in rat hepatocytes. Am J Physiol (1993) 1.49
Role of the mitochondrial permeability transition in apoptotic and necrotic death after ischemia/reperfusion injury to hepatocytes. Curr Mol Med (2003) 1.47
Are patients with cirrhotic stage primary sclerosing cholangitis at risk for the development of hepatocellular cancer? J Hepatol (1997) 1.47
Secretin stimulates exocytosis in isolated bile duct epithelial cells by a cyclic AMP-mediated mechanism. J Biol Chem (1992) 1.47
Liver cell necrosis: cellular mechanisms and clinical implications. Gastroenterology (1995) 1.47
Ischemic-type biliary complications after orthotopic liver transplantation. Hepatology (1992) 1.46
Cholestasis confers resistance to the rat liver mitochondrial permeability transition. Gastroenterology (1998) 1.46
Glycochenodeoxycholate-induced lethal hepatocellular injury in rat hepatocytes. Role of ATP depletion and cytosolic free calcium. J Clin Invest (1993) 1.46
Biliary excretion in primary rat hepatocytes cultured in a collagen-sandwich configuration. Am J Physiol (1999) 1.45
Death receptors in liver biology and pathobiology. Hepatology (1999) 1.45
Chronic enteral ethanol treatment causes hypoxia in rat liver tissue in vivo. Hepatology (1997) 1.45
[Interventional emergency embolization for severe pelvic ring fractures with arterial bleeding. Integration into the early clinical treatment algorithm]. Unfallchirurg (2008) 1.45
Pathogenesis, diagnosis, and treatment of alcoholic liver disease. Mayo Clin Proc (2001) 1.45
Kupffer cell sensitization by alcohol involves increased permeability to gut-derived endotoxin. Alcohol Clin Exp Res (2001) 1.44
The mitochondrial permeability transition augments Fas-induced apoptosis in mouse hepatocytes. J Biol Chem (2000) 1.44
Orthotopic liver transplantation for preoperative early-stage hepatocellular carcinoma. Mayo Clin Proc (1994) 1.43
Increases of intracellular magnesium promote glycodeoxycholate-induced apoptosis in rat hepatocytes. J Clin Invest (1994) 1.42
Nitric oxide-mediated inhibition of DNA repair potentiates oxidative DNA damage in cholangiocytes. Gastroenterology (2001) 1.40
Physiology and pathophysiology of apoptosis in epithelial cells of the liver, pancreas, and intestine. Am J Physiol (1997) 1.40
Mitochondrial free calcium transients during excitation-contraction coupling in rabbit cardiac myocytes. FEBS Lett (1996) 1.39
[Effects of desflurane on liver microcirculation in comparison with isoflurane and pentobarbital. An intravital microscopy study in the rat]. Anasthesiol Intensivmed Notfallmed Schmerzther (1995) 1.39
Apoptosis and hepatobiliary disease. Hepatology (1995) 1.39
Cathepsin B knockout mice are resistant to tumor necrosis factor-alpha-mediated hepatocyte apoptosis and liver injury: implications for therapeutic applications. Am J Pathol (2001) 1.39
Prognostic role of vascular endothelial growth factor in hepatocellular carcinoma: systematic review and meta-analysis. Br J Cancer (2009) 1.38
The involvement of Kupffer cells in carbon tetrachloride toxicity. Toxicol Appl Pharmacol (1993) 1.38
Extracellular acidosis delays onset of cell death in ATP-depleted hepatocytes. Am J Physiol (1988) 1.38
Proteasome inhibition causes apoptosis of normal human plasma cells preventing alloantibody production. Am J Transplant (2008) 1.37
Inhibition of glucagon effects in perfused rat liver by (+)decanoylcarnitine. J Biol Chem (1969) 1.37
Clinical Trial of the Pan-Caspase Inhibitor, IDN-6556, in Human Liver Preservation Injury. Am J Transplant (2007) 1.36
Interaction of mixed-function oxidation with biosynthetic processes. 1. Inhibition of gluconeogenesis by aminopyrine in perfused rat liver. Eur J Biochem (1973) 1.36
Cryptosporidium parvum activates nuclear factor kappaB in biliary epithelia preventing epithelial cell apoptosis. Gastroenterology (2001) 1.36
Surgical resection versus transplantation for early hepatocellular carcinoma: clues for the best strategy. Hepatology (2000) 1.35
Cathepsin B contributes to bile salt-induced apoptosis of rat hepatocytes. Gastroenterology (1997) 1.35
The mitochondrial permeability transition mediates both necrotic and apoptotic death of hepatocytes exposed to Br-A23187. Toxicol Appl Pharmacol (1999) 1.34
The bile acid glycochenodeoxycholate induces trail-receptor 2/DR5 expression and apoptosis. J Biol Chem (2001) 1.34
Irreversible injury in anoxic hepatocytes precipitated by an abrupt increase in plasma membrane permeability. FASEB J (1988) 1.34
Development of a new, simple rat model of early alcohol-induced liver injury based on sensitization of Kupffer cells. Hepatology (1999) 1.33
Lipopolysaccharide induces cholangiocyte proliferation via an interleukin-6-mediated activation of p44/p42 mitogen-activated protein kinase. Hepatology (1999) 1.33
Mitochondrial calcium transients in adult rabbit cardiac myocytes: inhibition by ruthenium red and artifacts caused by lysosomal loading of Ca(2+)-indicating fluorophores. Biophys J (2000) 1.32