Published in Hepatology on June 01, 1999
Cellular and molecular mechanisms of liver injury. Gastroenterology (2008) 3.02
Human immunodeficiency virus-related microbial translocation and progression of hepatitis C. Gastroenterology (2008) 3.00
Microbial translocation across the GI tract. Annu Rev Immunol (2012) 2.30
Enteric dysbiosis associated with a mouse model of alcoholic liver disease. Hepatology (2010) 2.23
Alcohol, inflammation, and gut-liver-brain interactions in tissue damage and disease development. World J Gastroenterol (2010) 1.45
Deficiency of intestinal mucin-2 ameliorates experimental alcoholic liver disease in mice. Hepatology (2013) 1.18
Metabolomic profiling of a modified alcohol liquid diet model for liver injury in the mouse uncovers new markers of disease. Toxicol Appl Pharmacol (2008) 1.14
Rodent models of alcoholic liver disease: of mice and men. Alcohol (2012) 1.11
Intestinal damage mediated by Kupffer cells in rats with endotoxemia. World J Gastroenterol (2002) 1.09
The intestinal microbiome and the leaky gut as therapeutic targets in alcoholic liver disease. Front Physiol (2012) 1.07
Circulating sCD14 is associated with virological response to pegylated-interferon-alpha/ribavirin treatment in HIV/HCV co-infected patients. PLoS One (2012) 1.06
Body-on-a-chip simulation with gastrointestinal tract and liver tissues suggests that ingested nanoparticles have the potential to cause liver injury. Lab Chip (2014) 1.04
Expression of lipopolysaccharide binding protein and its receptor CD14 in experimental alcoholic liver disease. World J Gastroenterol (2001) 1.03
Kupffer cells are depleted with HIV immunodeficiency and partially recovered with antiretroviral immune reconstitution. AIDS (2009) 1.00
Milk osteopontin, a nutritional approach to prevent alcohol-induced liver injury. Am J Physiol Gastrointest Liver Physiol (2013) 0.96
Bacterial translocation and changes in the intestinal microbiome associated with alcoholic liver disease. World J Hepatol (2012) 0.95
Effect of leflunomide on immunological liver injury in mice. World J Gastroenterol (2003) 0.94
Curcumin decreased oxidative stress, inhibited NF-kappaB activation, and improved liver pathology in ethanol-induced liver injury in rats. J Biomed Biotechnol (2009) 0.93
A human-type nonalcoholic steatohepatitis model with advanced fibrosis in rabbits. Am J Pathol (2010) 0.92
Experimental rat model for alcohol-induced osteonecrosis of the femoral head. Int J Exp Pathol (2013) 0.91
Histamine dihydrochloride protects against early alcohol-induced liver injury in a rat model. Inflammation (2003) 0.82
Effects of daily, light and moderate-heavy ethanol exposure on extent of hepatic injury and recovery following toxin-induced acute hepatitis in rats. Dig Dis Sci (2003) 0.82
Tumor necrosis factor-alpha can provoke cleavage and activation of sterol regulatory element-binding protein in ethanol-exposed cells via a caspase-dependent pathway that is cholesterol insensitive. J Biol Chem (2008) 0.81
Arachidonic acid stimulates TNFα production in Kupffer cells via a reactive oxygen species-pERK1/2-Egr1-dependent mechanism. Am J Physiol Gastrointest Liver Physiol (2012) 0.80
Synthesis of endotoxin receptor CD14 protein in Kupffer cells and its role in alcohol-induced liver disease. World J Gastroenterol (2003) 0.80
Expression of CD14 protein and its gene in liver sinusoidal endothelial cells during endotoxemia. World J Gastroenterol (2002) 0.79
Long-term alcohol consumption increases pro-matrix metalloproteinase-9 levels via oxidative stress. J Med Toxicol (2010) 0.79
HTK-N, a modified HTK solution, decreases preservation injury in a model of microsteatotic rat liver transplantation. Langenbecks Arch Surg (2012) 0.78
Thalidomide Prevents Alcoholic Liver Injury in Rats Through Inhibition of Kupffer Cell Sensitization. Comp Hepatol (2004) 0.77
The Effects of Syzygium samarangense, Passiflora edulis and Solanum muricatum on Alcohol-Induced Liver Injury. Int J Mol Sci (2016) 0.75
Alcoholic Steatosis in Different Strains of Rat: A Comparative Study. J Drug Alcohol Res (2015) 0.75
Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1. Science (1987) 10.25
The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy. Biochim Biophys Acta (1998) 4.50
Correlation between liver histology and novel magnetic resonance imaging in adult patients with non-alcoholic fatty liver disease - MRI accurately quantifies hepatic steatosis in NAFLD. Aliment Pharmacol Ther (2012) 3.25
Essential role of tumor necrosis factor alpha in alcohol-induced liver injury in mice. Gastroenterology (1999) 3.24
Fewer adhesions induced by laparoscopic surgery? Surg Endosc (2004) 3.11
Hepatic microsomal ethanol oxidation. Hydrogen peroxide formation and the role of catalase. Eur J Biochem (1972) 3.11
Hepatic stellate cells as a target for the treatment of liver fibrosis. Semin Liver Dis (2001) 2.98
Nrf2-deficient female mice develop lupus-like autoimmune nephritis. Kidney Int (2001) 2.90
Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice. Hepatology (2001) 2.72
CRMP-2 induces axons in cultured hippocampal neurons. Nat Neurosci (2001) 2.70
NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease. J Clin Invest (2000) 2.67
Alveolar fluid clearance in the resected human lung. Am J Respir Crit Care Med (1994) 2.63
Antibiotics prevent liver injury in rats following long-term exposure to ethanol. Gastroenterology (1995) 2.58
Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity. J Immunol (1999) 2.55
Efficient transformation of chicken embryo fibroblasts by c-Jun requires structural modification in coding and noncoding sequences. Genes Dev (1990) 2.46
Effect of insertions, deletions, and double-strand breaks on homologous recombination in mouse L cells. Mol Cell Biol (1985) 2.44
Infectious cell entry mechanism of influenza virus. J Virol (1982) 2.41
Inactivation of Kupffer cells prevents early alcohol-induced liver injury. Hepatology (1994) 2.37
Uveal effusion syndrome: clinical features, surgical treatment, histologic examination of the sclera, and pathophysiology. Ophthalmology (2000) 2.36
Sulforaphane targets pancreatic tumour-initiating cells by NF-kappaB-induced antiapoptotic signalling. Gut (2008) 2.36
The role of TGFbeta1 in initiating hepatic stellate cell activation in vivo. J Hepatol (1999) 2.35
Antibodies to tumor necrosis factor alfa attenuate hepatic necrosis and inflammation caused by chronic exposure to ethanol in the rat. Hepatology (1997) 2.35
Failure of parturition in mice lacking the prostaglandin F receptor. Science (1997) 2.27
NFkappaB prevents apoptosis and liver dysfunction during liver regeneration. J Clin Invest (1998) 2.27
Biochemical characterization and biologic actions of two toxins (D-1 and D-2) from Clostridium difficile. Rev Infect Dis (1984) 2.26
A randomized, controlled study to assess the conversion from calcineurin-inhibitors to everolimus after liver transplantation--PROTECT. Am J Transplant (2012) 2.24
Multicentre prospective phase II trial of gefitinib for advanced non-small cell lung cancer with epidermal growth factor receptor mutations: results of the West Japan Thoracic Oncology Group trial (WJTOG0403). Br J Cancer (2008) 2.19
Elevated expression of messenger RNA for peripheral myelin protein 22 in biopsied peripheral nerves of patients with Charcot-Marie-Tooth disease type 1A. Ann Neurol (1994) 2.18
Inhibition of NFkappaB in activated rat hepatic stellate cells by proteasome inhibitors and an IkappaB super-repressor. Hepatology (1998) 2.18
The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells. Involvement of death receptor-related signaling pathways. J Biol Chem (2000) 2.17
Reperfusion after liver transplantation in rats differentially activates the mitogen-activated protein kinases. Hepatology (1997) 2.14
Continuous Fick cardiac output measurement during exercise by monitoring of mixed venous oxygen saturation and oxygen uptake. Chest (1993) 2.13
Prions prevent neuronal cell-line death. Nature (1999) 2.13
Influence of test technique on sensitization status of patients on the kidney transplant waiting list. Am J Transplant (2013) 2.12
Validity of 18F-fluorodeoxyglucose imaging with a dual-head coincidence gamma camera for detection of myocardial viability. J Nucl Med (1999) 2.06
Circulatory and respiratory complications of carbon dioxide insufflation. Dig Surg (2004) 2.06
Patent ductus arteriosus and neonatal death in prostaglandin receptor EP4-deficient mice. Biochem Biophys Res Commun (1998) 2.04
Posttranscriptional regulation of collagen alpha1(I) mRNA in hepatic stellate cells. Mol Cell Biol (1997) 2.04
Metabolism of iodine-123-BMIPP in perfused rat hearts. J Nucl Med (1995) 2.02
Continuous ambulatory radionuclide monitoring of left ventricular function: effect of body position during ergometer exercise. J Nucl Med (1997) 1.99
Continuous determination of cardiac output using a flow-directed Doppler pulmonary artery catheter. J Cardiothorac Vasc Anesth (1991) 1.97
Evidence that hypoxia markers detect oxygen gradients in liver: pimonidazole and retrograde perfusion of rat liver. Br J Cancer (1995) 1.96
Aldehyde dehydrogenase genotypes in Japanese alcoholics. Lancet (1994) 1.91
Tumor necrosis factor alpha stimulates AP-1 activity through prolonged activation of the c-Jun kinase. J Biol Chem (1994) 1.90
Mechanisms of hepatic toxicity. I. TNF-induced liver injury. Am J Physiol (1998) 1.89
Proton chemical shift imaging in normal pressure hydrocephalus. AJNR Am J Neuroradiol (2001) 1.89
The role of Smad3 in mediating mouse hepatic stellate cell activation. Hepatology (2001) 1.88
Robot-assisted abdominal surgery. Br J Surg (2004) 1.85
ProTherm: Thermodynamic Database for Proteins and Mutants. Nucleic Acids Res (1999) 1.85
The enzymatic defect in variegate prophyria. Studies with human cultured skin fibroblasts. N Engl J Med (1980) 1.79
alpha-galactosylceramide induces early B-cell activation through IL-4 production by NKT cells. Cell Immunol (2000) 1.77
Apoptosis is an innate defense function of macrophages against Mycobacterium tuberculosis. Mucosal Immunol (2011) 1.76
Metabolic effects of ethanol in perfused rat liver. J Biol Chem (1969) 1.73
Flavin and pyridine nucleotide oxidation-reduction changes in perfused rat liver. I. Anoxia and subcellular localization of fluorescent flavoproteins. J Biol Chem (1969) 1.73
Mortality, major cause of moribundity, and spontaneous tumors in CD-1 mice. Toxicol Pathol (1988) 1.73
Double-strand gap repair results in homologous recombination in mouse L cells. Proc Natl Acad Sci U S A (1986) 1.72
Mice lacking inducible nitric oxide synthase have improved left ventricular contractile function and reduced apoptotic cell death late after myocardial infarction. Circ Res (2001) 1.70
The role of Kupffer cell oxidant production in early ethanol-induced liver disease. Free Radic Biol Med (2001) 1.69
Oncogenic Ras activates c-Jun via a separate pathway from the activation of extracellular signal-regulated kinases. Proc Natl Acad Sci U S A (1994) 1.67
Reductive metabolism of the hypoxia marker pimonidazole is regulated by oxygen tension independent of the pyridine nucleotide redox state. Eur J Biochem (1998) 1.67
The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release. Mol Cell Biol (1998) 1.66
Change in vasoconstrictive function during prolonged nonpulsatile left heart bypass. Artif Organs (2001) 1.65
Attenuation of CCl(4)-induced hepatic fibrosis by GdCl(3) treatment or dietary glycine. Am J Physiol Gastrointest Liver Physiol (2001) 1.64
Effects of reduced pulse pressure to the cerebral metabolism during prolonged nonpulsatile left heart bypass. Artif Organs (2000) 1.64
Reperfusion injury after liver preservation for transplantation. Annu Rev Pharmacol Toxicol (1997) 1.63
NF-kappaB inactivation converts a hepatocyte cell line TNF-alpha response from proliferation to apoptosis. Am J Physiol (1998) 1.63
Role of structural and sequence information in the prediction of protein stability changes: comparison between buried and partially buried mutations. Protein Eng (1999) 1.61
MR tractography depicting damage to the arcuate fasciculus in a patient with conduction aphasia. Neurology (2007) 1.60
Clinical efficacy and safety of donepezil on cognitive and global function in patients with Alzheimer's disease. A 24-week, multicenter, double-blind, placebo-controlled study in Japan. E2020 Study Group. Dement Geriatr Cogn Disord (2001) 1.59
Triptolide attenuates pulmonary arterial hypertension and neointimal formation in rats. Am J Respir Crit Care Med (2000) 1.59
Ischemic preconditioning of rat livers against cold storage-reperfusion injury: role of nonparenchymal cells and the phenomenon of heterologous preconditioning. Liver Transpl (2001) 1.59
Tumor necrosis factor alpha inhibits collagen gene transcription and collagen synthesis in cultured human fibroblasts. J Biol Chem (1988) 1.58
Alcohol causes both tolerance and sensitization of rat Kupffer cells via mechanisms dependent on endotoxin. Gastroenterology (1998) 1.58
Plasma levels of vascular endothelial growth factor and pigment epithelium-derived factor before and after intravitreal injection of bevacizumab. Br J Ophthalmol (2010) 1.55
The effectiveness of lymphangiography as a treatment method for various chyle leakages. Br J Radiol (2008) 1.55
Cloning and structural analysis of cDNA and the gene for mouse transcription factor UBF. Nucleic Acids Res (1991) 1.55
Influence of environmental factors on foetal growth in man. Lancet (1967) 1.55
Regulatory elements in the 5'-flanking region and the first intron contribute to transcriptional control of the mouse alpha 1 type I collagen gene. Mol Cell Biol (1989) 1.55
CD40 activates NF-kappa B and c-Jun N-terminal kinase and enhances chemokine secretion on activated human hepatic stellate cells. J Immunol (2001) 1.54
The many facets of reperfusion injury. Gastroenterology (1995) 1.53
A simplified method for the preparation of transcriptionally active liver nuclear extracts. DNA Cell Biol (1990) 1.53
Stimulation of collagen gene expression by ascorbic acid in cultured human fibroblasts. A role for lipid peroxidation? J Biol Chem (1989) 1.52
Expression of pigment epithelium derived factor and vascular endothelial growth factor in choroidal neovascular membranes and polypoidal choroidal vasculopathy. Br J Ophthalmol (2004) 1.52
Inhibition of proinflammatory molecule production by adenovirus-mediated expression of a nuclear factor kappaB super-repressor in human intestinal epithelial cells. J Immunol (1998) 1.51
Randomized clinical trial of stapler versus clamp-crushing transection in elective liver resection. Br J Surg (2014) 1.50
Improved method for post-embedding cytochemistry using reduced osmium and LR white resin. J Histochem Cytochem (1994) 1.50
Reduced early alcohol-induced liver injury in CD14-deficient mice. J Immunol (2001) 1.50
Purification and properties of beta-ketothiolase from Zoogloea ramigera. Arch Microbiol (1978) 1.48
Mitochondrial dysfunction in the pathogenesis of necrotic and apoptotic cell death. J Bioenerg Biomembr (1999) 1.46