PubRank

Frank Buchholz

Author PubWeight™ 96.82‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals. Nat Methods 2008 6.51
2 Minimizing the risk of reporting false positives in large-scale RNAi screens. Nat Methods 2006 5.96
3 Systems survey of endocytosis by multiparametric image analysis. Nature 2010 5.03
4 Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science 2010 4.69
5 Genome-scale RNAi profiling of cell division in human tissue culture cells. Nat Cell Biol 2007 3.91
6 Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I. Nature 2006 3.81
7 An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division. Nature 2004 3.69
8 A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity. Cell Stem Cell 2009 3.55
9 HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity. Curr Biol 2009 2.98
10 Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells. Proc Natl Acad Sci U S A 2002 2.85
11 Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies. Nat Methods 2007 2.83
12 HIV-1 proviral DNA excision using an evolved recombinase. Science 2007 2.81
13 RNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cells. Proc Natl Acad Sci U S A 2005 2.59
14 DEQOR: a web-based tool for the design and quality control of siRNAs. Nucleic Acids Res 2004 1.97
15 Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice. Dis Model Mech 2009 1.97
16 A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia. PLoS Biol 2010 1.77
17 Selective expression of the Cre recombinase in late-stage thymocytes using the distal promoter of the Lck gene. J Immunol 2005 1.68
18 Production of endoribonuclease-prepared short interfering RNAs for gene silencing in mammalian cells. Nat Methods 2005 1.62
19 Alternative approaches for efficient inhibition of hepatitis C virus RNA replication by small interfering RNAs. J Virol 2004 1.61
20 A systematic RNAi synthetic interaction screen reveals a link between p53 and snoRNP assembly. Nat Cell Biol 2011 1.54
21 Comparative profiling identifies C13orf3 as a component of the Ska complex required for mammalian cell division. EMBO J 2009 1.51
22 RAD21 cooperates with pluripotency transcription factors in the maintenance of embryonic stem cell identity. PLoS One 2011 1.38
23 Tissue-specific RNA interference in postimplantation mouse embryos with endoribonuclease-prepared short interfering RNA. Proc Natl Acad Sci U S A 2002 1.23
24 Tandem affinity purification of functional TAP-tagged proteins from human cells. Nat Protoc 2007 1.15
25 The FunGenES database: a genomics resource for mouse embryonic stem cell differentiation. PLoS One 2009 1.15
26 A domesticated transposon mediates the effects of a single-nucleotide polymorphism responsible for enhanced muscle growth. EMBO Rep 2010 1.14
27 Interaction between AP-5 and the hereditary spastic paraplegia proteins SPG11 and SPG15. Mol Biol Cell 2013 1.12
28 Highly significant antiviral activity of HIV-1 LTR-specific tre-recombinase in humanized mice. PLoS Pathog 2013 1.08
29 The histone demethylase UTX regulates stem cell migration and hematopoiesis. Blood 2013 1.06
30 Systems biology of mammalian cell division. Cell Cycle 2008 1.04
31 HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment. EMBO J 2013 1.04
32 Crystal structure of a wild-type Cre recombinase-loxP synapse reveals a novel spacer conformation suggesting an alternative mechanism for DNA cleavage activation. Nucleic Acids Res 2003 1.04
33 SeLOX--a locus of recombination site search tool for the detection and directed evolution of site-specific recombination systems. Nucleic Acids Res 2010 1.02
34 Tissue-specific RNA interference in post-implantation mouse embryos using directional electroporation and whole embryo culture. Differentiation 2004 0.93
35 Runx1 is essential at two stages of early murine B-cell development. Blood 2013 0.92
36 Polycomb group ring finger 1 cooperates with Runx1 in regulating differentiation and self-renewal of hematopoietic cells. Blood 2012 0.92
37 Vika/vox, a novel efficient and specific Cre/loxP-like site-specific recombination system. Nucleic Acids Res 2012 0.92
38 RUNX1 DNA-binding mutants, associated with minimally differentiated acute myelogenous leukemia, disrupt myeloid differentiation. Cancer Res 2007 0.91
39 Quantitative interaction screen of telomeric repeat-containing RNA reveals novel TERRA regulators. Genome Res 2013 0.91
40 The symplekin/ZONAB complex inhibits intestinal cell differentiation by the repression of AML1/Runx1. Gastroenterology 2009 0.89
41 Excision of HIV-1 proviral DNA by recombinant cell permeable tre-recombinase. PLoS One 2012 0.89
42 Combined RNAi and localization for functionally dissecting long noncoding RNAs. Nat Methods 2012 0.88
43 Three LIF-dependent signatures and gene clusters with atypical expression profiles, identified by transcriptome studies in mouse ES cells and early derivatives. BMC Genomics 2009 0.88
44 Functional genomic analysis of cell division by endoribonuclease-prepared siRNAs. Cell Cycle 2005 0.87
45 From RNAi screens to molecular function in embryonic stem cells. Stem Cell Rev 2012 0.85
46 RNA interference: gene silencing in the fast lane. Semin Cancer Biol 2003 0.83
47 An RNA interference phenotypic screen identifies a role for FGF signals in colon cancer progression. PLoS One 2011 0.83
48 RNAi in embryonic stem cells. Stem Cell Rev 2006 0.82
49 Engineering of a target site-specific recombinase by a combined evolution- and structure-guided approach. Nucleic Acids Res 2012 0.82
50 Designing efficient and specific endoribonuclease-prepared siRNAs. Methods Mol Biol 2013 0.80
51 Production of Endoribonuclease-Prepared Short Interfering RNAs (esiRNAs) for Specific and Effective Gene Silencing in Mammalian Cells. CSH Protoc 2007 0.79
52 PhenoFam-gene set enrichment analysis through protein structural information. BMC Bioinformatics 2010 0.79
53 MISSION esiRNA for RNAi screening in mammalian cells. J Vis Exp 2010 0.78
54 High-throughput RNAi screening in mammalian cells with esiRNAs. Methods 2010 0.78
55 3D profile-based approach to proteome-wide discovery of novel human chemokines. PLoS One 2012 0.77
56 Ribosome biogenesis and p53: who is regulating whom? Cell Cycle 2011 0.77
57 SKAnking with Ska3: essential role of Ska3 in cell division revealed by combined phenotypic profiling. Cell Cycle 2009 0.76
58 [Revolutionizing HIV-therapy by Tre-Recombinase? Initial observations and current state of development]. MMW Fortschr Med 2013 0.75