Published in Am J Psychiatry on April 01, 2010
High dimensional endophenotype ranking in the search for major depression risk genes. Biol Psychiatry (2011) 2.23
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Personalized medicine for depression: can we match patients with treatments? Am J Psychiatry (2010) 2.06
Glycine and a glycine dehydrogenase (GLDC) SNP as citalopram/escitalopram response biomarkers in depression: pharmacometabolomics-informed pharmacogenomics. Clin Pharmacol Ther (2010) 1.74
Cognitive mechanisms of treatment in depression. Neuropsychopharmacology (2011) 1.43
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Genetic predictors of response to serotonergic and noradrenergic antidepressants in major depressive disorder: a genome-wide analysis of individual-level data and a meta-analysis. PLoS Med (2012) 1.19
Biomarkers to predict antidepressant response. Curr Psychiatry Rep (2010) 1.14
Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13). PLoS One (2012) 1.14
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Pharmacogenomics of selective serotonin reuptake inhibitor treatment for major depressive disorder: genome-wide associations and functional genomics. Pharmacogenomics J (2012) 0.98
Copy number variants in pharmacogenetic genes. Trends Mol Med (2011) 0.96
Proteoglycans and neuronal migration in the cerebral cortex during development and disease. Front Neurosci (2015) 0.95
Biomarkers predicting treatment outcome in depression: what is clinically significant? Pharmacogenomics (2012) 0.93
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Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains. Psychopharmacology (Berl) (2011) 0.90
A genome-wide association study of a sustained pattern of antidepressant response. J Psychiatr Res (2013) 0.90
The norepinephrine transporter gene is a candidate gene for panic disorder. J Neural Transm (Vienna) (2011) 0.90
Pharmacogenomics and patient care: one size does not fit all. Sci Transl Med (2012) 0.89
Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: a genome-wide association and polygenic scoring study. Am J Med Genet B Neuropsychiatr Genet (2014) 0.88
Pharmacogenomics discovery and implementation in genome-wide association studies era. Wiley Interdiscip Rev Syst Biol Med (2012) 0.88
Leptin receptor deficiency confers resistance to behavioral effects of fluoxetine and desipramine via separable substrates. Transl Psychiatry (2014) 0.87
Citalopram versus other anti-depressive agents for depression. Cochrane Database Syst Rev (2012) 0.87
TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive disorder: pharmacometabolomics-informed pharmacogenomics. Mol Psychiatry (2016) 0.86
The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response. Transl Psychiatry (2015) 0.85
Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Biol Psychiatry (2016) 0.85
Epigenetic alterations in depression and antidepressant treatment. Dialogues Clin Neurosci (2014) 0.85
Investigation of blood mRNA biomarkers for suicidality in an independent sample. Transl Psychiatry (2014) 0.85
Using patient self-reports to study heterogeneity of treatment effects in major depressive disorder. Epidemiol Psychiatr Sci (2016) 0.84
Polygenic interactions with environmental adversity in the aetiology of major depressive disorder. Psychol Med (2015) 0.84
Cytokine variations and mood disorders: influence of social stressors and social support. Front Neurosci (2014) 0.83
Testing a machine-learning algorithm to predict the persistence and severity of major depressive disorder from baseline self-reports. Mol Psychiatry (2016) 0.83
Putative transcriptomic biomarkers in the inflammatory cytokine pathway differentiate major depressive disorder patients from control subjects and bipolar disorder patients. PLoS One (2014) 0.82
Pharmacogenetics of antidepressants. Front Pharmacol (2011) 0.82
PharmGKB summary: citalopram pharmacokinetics pathway. Pharmacogenet Genomics (2011) 0.82
Resistance to antidepressant treatment is associated with polymorphisms in the leptin gene, decreased leptin mRNA expression, and decreased leptin serum levels. Eur Neuropsychopharmacol (2012) 0.82
DNA methylation in interleukin-11 predicts clinical response to antidepressants in GENDEP. Transl Psychiatry (2013) 0.81
Validation of candidate genes associated with cardiovascular risk factors in psychiatric patients. Prog Neuropsychopharmacol Biol Psychiatry (2011) 0.81
The pharmacogenetics of depression: enter the GWAS. Am J Psychiatry (2010) 0.80
Machine learning, statistical learning and the future of biological research in psychiatry. Psychol Med (2016) 0.79
Exploring the effects of polymorphisms on cis-regulatory signal transduction response. Trends Mol Med (2012) 0.79
Genetic Contributions of Inflammation to Depression. Neuropsychopharmacology (2016) 0.79
Antidepressant treatment response is modulated by genetic and environmental factors and their interactions. Ann Gen Psychiatry (2014) 0.78
Genome-wide approaches to antidepressant treatment: working towards understanding and predicting response. Genome Med (2012) 0.78
Sexual dysfunction during treatment with serotonergic and noradrenergic antidepressants: clinical description and the role of the 5-HTTLPR. World J Biol Psychiatry (2011) 0.78
Absolute Measurements of Macrophage Migration Inhibitory Factor and Interleukin-1-β mRNA Levels Accurately Predict Treatment Response in Depressed Patients. Int J Neuropsychopharmacol (2016) 0.78
Genome-wide association study of response to cognitive-behavioural therapy in children with anxiety disorders. Br J Psychiatry (2016) 0.78
A genome-wide association study of antidepressant response in Koreans. Transl Psychiatry (2015) 0.77
Genetics in child and adolescent psychiatry: methodological advances and conceptual issues. Eur Child Adolesc Psychiatry (2015) 0.76
Highly polygenic architecture of antidepressant treatment response: Comparative analysis of SSRI and NRI treatment in an animal model of depression. Am J Med Genet B Neuropsychiatr Genet (2016) 0.75
Genetic variants in combination with early partial improvement as a clinical utility predictor of treatment outcome in major depressive disorder: the result of two pooled RCTs. Transl Psychiatry (2015) 0.75
Immune signatures and disorder-specific patterns in a cross-disorder gene expression analysis. Br J Psychiatry (2016) 0.75
Genome-wide association study of antidepressant response: involvement of the inorganic cation transmembrane transporter activity pathway. BMC Psychiatry (2016) 0.75
Convergent evidence from mouse and human studies suggests the involvement of zinc finger protein 326 gene in antidepressant treatment response. PLoS One (2012) 0.75
Analysis of 23andMe antidepressant efficacy survey data: implication of circadian rhythm and neuroplasticity in bupropion response. Transl Psychiatry (2016) 0.75
No support for replication of the genetic variants identified by a recent mega-analysis of the treatment response to antidepressants. J Hum Genet (2015) 0.75
Identifying genetic loci affecting antidepressant drug response in depression using drug-gene interaction models. Pharmacogenomics (2016) 0.75
Genome-wide scan of job-related exhaustion with three replication studies implicate a susceptibility variant at the UST gene locus. Hum Mol Genet (2013) 0.75
Pharmacogenomics in the treatment of mood disorders: Strategies and Opportunities for personalized psychiatry. EPMA J (2017) 0.75
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet (2008) 30.20
International network of cancer genome projects. Nature (2010) 20.35
Large recurrent microdeletions associated with schizophrenia. Nature (2008) 20.25
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature (2008) 16.10
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet (2009) 15.15
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat Genet (2009) 14.86
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet (2007) 13.74
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet (2007) 12.62
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature (2010) 12.27
Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nat Genet (2008) 10.52
Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet (2008) 10.49
Common variants conferring risk of schizophrenia. Nature (2009) 10.37
Wake-up call for British psychiatry. Br J Psychiatry (2008) 10.30
Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA (2010) 9.52
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet (2011) 9.23
Genetic variants associated with Lp(a) lipoprotein level and coronary disease. N Engl J Med (2009) 8.73
Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4. PLoS Genet (2007) 8.63
Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet (2010) 8.55
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
Genome-wide association study identifies five susceptibility loci for glioma. Nat Genet (2009) 7.62
Mapping complex disease traits with global gene expression. Nat Rev Genet (2009) 7.44
Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet (2013) 7.44
Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia. Am J Hum Genet (2003) 6.63
A mega-analysis of genome-wide association studies for major depressive disorder. Mol Psychiatry (2012) 6.34
Microduplications of 16p11.2 are associated with schizophrenia. Nat Genet (2009) 6.13
Lung cancer susceptibility locus at 5p15.33. Nat Genet (2008) 5.99
DNA Pooling: a tool for large-scale association studies. Nat Rev Genet (2002) 5.66
A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. Am J Hum Genet (2009) 5.62
City living and urban upbringing affect neural social stress processing in humans. Nature (2011) 5.46
Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease. Hum Mol Genet (2005) 5.35
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease. Arch Neurol (2007) 5.09
A genome-wide investigation of SNPs and CNVs in schizophrenia. PLoS Genet (2009) 5.01
Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. Nat Genet (2008) 4.96
A genome-wide association study of alcohol dependence. Proc Natl Acad Sci U S A (2010) 4.94
Disruption of the neurexin 1 gene is associated with schizophrenia. Hum Mol Genet (2008) 4.78
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet (2013) 4.62
A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15. Nat Genet (2007) 4.61
Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease. Proc Natl Acad Sci U S A (2003) 4.44
Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. Nat Genet (2009) 4.38
The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease. Gastroenterology (2002) 4.20
Functional atlas of emotional faces processing: a voxel-based meta-analysis of 105 functional magnetic resonance imaging studies. J Psychiatry Neurosci (2009) 4.16
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes (2010) 4.07
A twin study of genetic relationships between psychotic symptoms. Am J Psychiatry (2002) 3.95
Pathway and network-based analysis of genome-wide association studies in multiple sclerosis. Hum Mol Genet (2009) 3.92
Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. PLoS Genet (2010) 3.91
Effect of 17q21 variants and smoking exposure in early-onset asthma. N Engl J Med (2008) 3.90
The European dimension for the mouse genome mutagenesis program. Nat Genet (2004) 3.84
Common variants at five new loci associated with early-onset inflammatory bowel disease. Nat Genet (2009) 3.82
Identifying depression in primary care: a comparison of different methods in a prospective cohort study. BMJ (2003) 3.78
Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet (2012) 3.73
Investigation of the fine structure of European populations with applications to disease association studies. Eur J Hum Genet (2008) 3.65
Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease. Arch Gen Psychiatry (2010) 3.64
The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption. Nat Med (2004) 3.63
Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study. Lancet Neurol (2010) 3.61
A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma. Nature (2011) 3.53
New parents and mental disorders: a population-based register study. JAMA (2006) 3.52
Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry. Proc Natl Acad Sci U S A (2009) 3.49