Published in J Innate Immun on August 01, 2009
Molecular insight into invasive group A streptococcal disease. Nat Rev Microbiol (2011) 2.81
Genomic analysis of immune response against Vibrio cholerae hemolysin in Caenorhabditis elegans. PLoS One (2012) 0.88
A1M/α1-microglobulin protects from heme-induced placental and renal damage in a pregnant sheep model of preeclampsia. PLoS One (2014) 0.85
The membrane bound LRR lipoprotein Slr, and the cell wall-anchored M1 protein from Streptococcus pyogenes both interact with type I collagen. PLoS One (2011) 0.85
Syncytiotrophoblast vesicles show altered micro-RNA and haemoglobin content after ex-vivo perfusion of placentas with haemoglobin to mimic preeclampsia. PLoS One (2014) 0.84
Region specific and worldwide distribution of collagen-binding M proteins with PARF motifs among human pathogenic streptococcal isolates. PLoS One (2012) 0.83
Annexin A2 mediates secretion of collagen VI, pulmonary elasticity and apoptosis of bronchial epithelial cells. J Cell Sci (2013) 0.82
Herpes simplex virus type 1 infection facilitates invasion of Staphylococcus aureus into the nasal mucosa and nasal polyp tissue. PLoS One (2012) 0.81
Identification of molecular mechanisms used by Finegoldia magna to penetrate and colonize human skin. Mol Microbiol (2014) 0.81
SpyAD, a moonlighting protein of group A Streptococcus contributing to bacterial division and host cell adhesion. Infect Immun (2014) 0.80
The BBA33 lipoprotein binds collagen and impacts Borrelia burgdorferi pathogenesis. Mol Microbiol (2015) 0.80
Novel role of the antimicrobial peptide LL-37 in the protection of neutrophil extracellular traps against degradation by bacterial nucleases. J Innate Immun (2014) 0.79
A novel role for pro-coagulant microvesicles in the early host defense against streptococcus pyogenes. PLoS Pathog (2013) 0.78
Modulation of Hemostatic and Inflammatory Responses by Leptospira Spp. PLoS Negl Trop Dis (2016) 0.77
Heterogeneity of Collagen VI Microfibrils: STRUCTURAL ANALYSIS OF NON-COLLAGENOUS REGIONS. J Biol Chem (2016) 0.76
Streptococcal surface proteins activate the contact system and control its antibacterial activity. J Biol Chem (2012) 0.76
Saliva-Induced Clotting Captures Streptococci: Novel Roles for Coagulation and Fibrinolysis in Host Defense and Immune Evasion. Infect Immun (2016) 0.76
The Collagen Binding Proteins of Streptococcus mutans and Related Streptococci. Mol Oral Microbiol (2016) 0.75
Vesicular Location and Transport of S100A8 and S100A9 Proteins in Monocytoid Cells. PLoS One (2015) 0.75
CD14 Is a Co-Receptor for TLR4 in the S100A9-Induced Pro-Inflammatory Response in Monocytes. PLoS One (2016) 0.75
Rheumatic Heart Disease and Myxomatous Degeneration: Differences and Similarities of Valve Damage Resulting from Autoimmune Reactions and Matrix Disorganization. PLoS One (2017) 0.75
M protein, a classical bacterial virulence determinant, forms complexes with fibrinogen that induce vascular leakage. Cell (2004) 2.46
The N terminus of the MUC2 mucin forms trimers that are held together within a trypsin-resistant core fragment. J Biol Chem (2002) 2.44
Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development. Proc Natl Acad Sci U S A (2013) 2.32
Antibody orientation at bacterial surfaces is related to invasive infection. J Exp Med (2012) 2.30
Pathogenic mechanisms in lupus nephritis: Nucleosomes bind aberrant laminin β1 with high affinity and colocalize in the electron-dense deposits. Arthritis Rheumatol (2014) 2.13
Beta2-glycoprotein I can exist in 2 conformations: implications for our understanding of the antiphospholipid syndrome. Blood (2010) 2.04
Coagulation, an ancestral serine protease cascade, exerts a novel function in early immune defense. Blood (2011) 1.87
Exosome uptake depends on ERK1/2-heat shock protein 27 signaling and lipid Raft-mediated endocytosis negatively regulated by caveolin-1. J Biol Chem (2013) 1.84
β₂-glycoprotein I: a novel component of innate immunity. Blood (2011) 1.75
COMP acts as a catalyst in collagen fibrillogenesis. J Biol Chem (2007) 1.74
Complexes of matrilin-1 and biglycan or decorin connect collagen VI microfibrils to both collagen II and aggrecan. J Biol Chem (2003) 1.72
The recombinant C-terminus of the human MUC2 mucin forms dimers in Chinese-hamster ovary cells and heterodimers with full-length MUC2 in LS 174T cells. Biochem J (2003) 1.67
The extracellular matrix and inflammation: fibromodulin activates the classical pathway of complement by directly binding C1q. J Biol Chem (2005) 1.61
Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in endothelial cells. Proc Natl Acad Sci U S A (2011) 1.52
Activation of the complement system generates antibacterial peptides. Proc Natl Acad Sci U S A (2004) 1.51
Dominant collagen VI mutations are a common cause of Ullrich congenital muscular dystrophy. Hum Mol Genet (2004) 1.51
Synergism between a novel chimeric lysin and oxacillin protects against infection by methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother (2010) 1.48
Antimicrobial activities of heparin-binding peptides. Eur J Biochem (2004) 1.46
Anesthesia aggravates lung damage and precipitates hypotension in endotoxemic sheep. Shock (2010) 1.44
In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner. Proc Natl Acad Sci U S A (2008) 1.44
Activation of the human contact system on neutrophil extracellular traps. J Innate Immun (2009) 1.41
Pathogen entrapment by transglutaminase--a conserved early innate immune mechanism. PLoS Pathog (2010) 1.39
Human IgG/Fc gamma R interactions are modulated by streptococcal IgG glycan hydrolysis. PLoS One (2008) 1.37
The contact system--a novel branch of innate immunity generating antibacterial peptides. EMBO J (2006) 1.36
Streptococcal M protein: a multipotent and powerful inducer of inflammation. J Immunol (2006) 1.36
Biglycan organizes collagen VI into hexagonal-like networks resembling tissue structures. J Biol Chem (2002) 1.35
Endoglycosidase treatment abrogates IgG arthritogenicity: importance of IgG glycosylation in arthritis. Eur J Immunol (2007) 1.32
Streptococcus pyogenes expressing M and M-like surface proteins are phagocytosed but survive inside human neutrophils. Cell Microbiol (2003) 1.29
IgG glycan hydrolysis attenuates ANCA-mediated glomerulonephritis. J Am Soc Nephrol (2010) 1.24
Regulation of complement by cartilage oligomeric matrix protein allows for a novel molecular diagnostic principle in rheumatoid arthritis. Arthritis Rheum (2010) 1.23
Suppression of sulfonylurea- and glucose-induced insulin secretion in vitro and in vivo in mice lacking the chloride transport protein ClC-3. Cell Metab (2009) 1.22
Distribution of PG-M/versican variants in human tissues and de novo expression of isoform V3 upon endothelial cell activation, migration, and neoangiogenesis in vitro. J Biol Chem (2002) 1.22
Short leucine-rich glycoproteins of the extracellular matrix display diverse patterns of complement interaction and activation. Mol Immunol (2008) 1.21
Collagen-binding proteoglycan fibromodulin can determine stroma matrix structure and fluid balance in experimental carcinoma. Proc Natl Acad Sci U S A (2007) 1.20
Disruption of platelet-derived chemokine heteromers prevents neutrophil extravasation in acute lung injury. Am J Respir Crit Care Med (2012) 1.18
Secretion of heparin-binding protein from human neutrophils is determined by its localization in azurophilic granules and secretory vesicles. Blood (2002) 1.18
Cysteine proteinase SpeB from Streptococcus pyogenes - a potent modifier of immunologically important host and bacterial proteins. Biol Chem (2011) 1.17
Molecular consequences of dominant Bethlem myopathy collagen VI mutations. Ann Neurol (2007) 1.15
Collagen VI glycine mutations: perturbed assembly and a spectrum of clinical severity. Ann Neurol (2008) 1.14
Low antibody levels against cell wall-attached proteins of Streptococcus pyogenes predispose for severe invasive disease. J Infect Dis (2004) 1.14
Structural basis for interactions between tenascins and lectican C-type lectin domains: evidence for a crosslinking role for tenascins. Structure (2004) 1.14
A novel localization of the G-protein-coupled CysLT1 receptor in the nucleus of colorectal adenocarcinoma cells. Cancer Res (2005) 1.13
Proteolysis of human thrombin generates novel host defense peptides. PLoS Pathog (2010) 1.12
Antimicrobial activity of histidine-rich peptides is dependent on acidic conditions. Biochim Biophys Acta (2007) 1.12
Domain 5 of high molecular weight kininogen is antibacterial. J Biol Chem (2005) 1.11
Podocytes express ADAMTS13 in normal renal cortex and in patients with thrombotic thrombocytopenic purpura. Br J Haematol (2007) 1.11
B cell activation by outer membrane vesicles--a novel virulence mechanism. PLoS Pathog (2010) 1.09
Antimicrobial peptides derived from growth factors. Growth Factors (2007) 1.09
Simvastatin reduces endotoxin-induced acute lung injury by decreasing neutrophil recruitment and radical formation. PLoS One (2012) 1.08
The leucine-rich repeat protein PRELP binds perlecan and collagens and may function as a basement membrane anchor. J Biol Chem (2002) 1.08
Tolerance induction with T cell-dependent protein antigens induces regulatory sialylated IgGs. J Allergy Clin Immunol (2012) 1.06
Chondroitin sulfate perlecan enhances collagen fibril formation. Implications for perlecan chondrodysplasias. J Biol Chem (2006) 1.06
Streptococcus pyogenes bacteria modulate membrane traffic in human neutrophils and selectively inhibit azurophilic granule fusion with phagosomes. Cell Microbiol (2006) 1.06
Kinked collagen VI tetramers and reduced microfibril formation as a result of Bethlem myopathy and introduced triple helical glycine mutations. J Biol Chem (2001) 1.06
The major bactericidal activity of human seminal plasma is zinc-dependent and derived from fragmentation of the semenogelins. J Immunol (2008) 1.05
Characterization of recombinant amino-terminal NC4 domain of human collagen IX: interaction with glycosaminoglycans and cartilage oligomeric matrix protein. J Biol Chem (2004) 1.05
Presence of activated mobile fibroblasts in bronchoalveolar lavage from patients with mild asthma. Am J Respir Crit Care Med (2004) 1.05
Streptococcal M proteins and their role as virulence determinants. Clin Chim Acta (2010) 1.05
The IgG-specific endoglycosidase EndoS inhibits both cellular and complement-mediated autoimmune hemolysis. Blood (2010) 1.05
Moraxella catarrhalis outer membrane vesicles carry β-lactamase and promote survival of Streptococcus pneumoniae and Haemophilus influenzae by inactivating amoxicillin. Antimicrob Agents Chemother (2011) 1.05
The fibrillogenic L178H variant of apolipoprotein A-I forms helical fibrils. J Lipid Res (2011) 1.05
Boosting antimicrobial peptides by hydrophobic oligopeptide end tags. J Biol Chem (2009) 1.03
All four members of the Ten-m/Odz family of transmembrane proteins form dimers. J Biol Chem (2002) 1.03
Complement inhibitor C4b-binding protein interacts directly with small glycoproteins of the extracellular matrix. J Immunol (2009) 1.03
EndoS from Streptococcus pyogenes is hydrolyzed by the cysteine proteinase SpeB and requires glutamic acid 235 and tryptophans for IgG glycan-hydrolyzing activity. BMC Microbiol (2008) 1.02
C-terminal peptides of tissue factor pathway inhibitor are novel host defense molecules. J Biol Chem (2010) 1.02
Multicomponent Moraxella catarrhalis outer membrane vesicles induce an inflammatory response and are internalized by human epithelial cells. Cell Microbiol (2010) 1.01
The human CXC chemokine granulocyte chemotactic protein 2 (GCP-2)/CXCL6 possesses membrane-disrupting properties and is antibacterial. Antimicrob Agents Chemother (2008) 1.01
ScFv antibody-induced translocation of cell-surface heparan sulfate proteoglycan to endocytic vesicles: evidence for heparan sulfate epitope specificity and role of both syndecan and glypican. J Biol Chem (2009) 1.01
Characterization and genome sequencing of two Propionibacterium acnes phages displaying pseudolysogeny. BMC Genomics (2011) 1.01
Localization of human neutrophil interleukin-8 (CXCL-8) to organelle(s) distinct from the classical granules and secretory vesicles. J Leukoc Biol (2005) 1.00
Successful treatment of experimental glomerulonephritis with IdeS and EndoS, IgG-degrading streptococcal enzymes. Nephrol Dial Transplant (2010) 1.00
M1 protein-dependent intracellular trafficking promotes persistence and replication of Streptococcus pyogenes in macrophages. J Innate Immun (2010) 0.99
Identification of proteins released by mammalian cells that mediate DNA internalization through proteoglycan-dependent macropinocytosis. J Biol Chem (2007) 0.99
Severe streptococcal infection is associated with M protein-induced platelet activation and thrombus formation. Mol Microbiol (2007) 0.99
Thrombin-activatable fibrinolysis inhibitor binds to Streptococcus pyogenes by interacting with collagen-like proteins A and B. J Biol Chem (2007) 0.99
Antibodies against a surface protein of Streptococcus pyogenes promote a pathological inflammatory response. PLoS Pathog (2008) 0.98
The antibacterial chemokine MIG/CXCL9 is constitutively expressed in epithelial cells of the male urogenital tract and is present in seminal plasma. J Interferon Cytokine Res (2008) 0.98
PACSIN 1 forms tetramers via its N-terminal F-BAR domain. FEBS J (2007) 0.98
Haemophilus influenzae protein E recognizes the C-terminal domain of vitronectin and modulates the membrane attack complex. Mol Microbiol (2011) 0.98
The C5 domain of the collagen VI alpha3(VI) chain is critical for extracellular microfibril formation and is present in the extracellular matrix of cultured cells. J Biol Chem (2006) 0.97
Haemophilus influenzae acquires vitronectin via the ubiquitous Protein F to subvert host innate immunity. Mol Microbiol (2013) 0.96
Magnetic nanoparticle-based isolation of endocytic vesicles reveals a role of the heat shock protein GRP75 in macromolecular delivery. Proc Natl Acad Sci U S A (2010) 0.96
Histidine-rich glycoprotein protects from systemic Candida infection. PLoS Pathog (2008) 0.95
Streptococcal protein FOG, a novel matrix adhesin interacting with collagen I in vivo. J Biol Chem (2005) 0.95
Mice lacking the extracellular matrix adaptor protein matrilin-2 develop without obvious abnormalities. Matrix Biol (2004) 0.95
ADAM12 is a four-leafed clover: the excised prodomain remains bound to the mature enzyme. J Biol Chem (2006) 0.95
Vitronectin binds to the head region of Moraxella catarrhalis ubiquitous surface protein A2 and confers complement-inhibitory activity. Mol Microbiol (2010) 0.94
Preservation of antimicrobial properties of complement peptide C3a, from invertebrates to humans. J Biol Chem (2006) 0.94
Histidine-rich glycoprotein exerts antibacterial activity. FEBS J (2007) 0.94
Up-regulation of A1M/α1-microglobulin in skin by heme and reactive oxygen species gives protection from oxidative damage. PLoS One (2011) 0.93
The GRACILE mutation introduced into Bcs1l causes postnatal complex III deficiency: a viable mouse model for mitochondrial hepatopathy. Hepatology (2010) 0.93
Histidine-rich glycoprotein promotes bacterial entrapment in clots and decreases mortality in a mouse model of sepsis. Blood (2010) 0.93
Treatment of invasive streptococcal infection with a peptide derived from human high-molecular weight kininogen. Blood (2009) 0.93
Activation of TAFI on the surface of Streptococcus pyogenes evokes inflammatory reactions by modulating the kallikrein/kinin system. J Innate Immun (2008) 0.93
Haemophilus influenzae protein E binds to the extracellular matrix by concurrently interacting with laminin and vitronectin. J Infect Dis (2011) 0.93
The antibacterial activity of peptides derived from human beta-2 glycoprotein I is inhibited by protein H and M1 protein from Streptococcus pyogenes. Mol Microbiol (2007) 0.93
Midkine and pleiotrophin have bactericidal properties: preserved antibacterial activity in a family of heparin-binding growth factors during evolution. J Biol Chem (2010) 0.92