Published in Nephrol Dial Transplant on March 10, 2010
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Glomerular activation of the lectin pathway of complement in IgA nephropathy is associated with more severe renal disease. J Am Soc Nephrol (2006) 1.72
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Biochemical and functional characterization of the interaction between pentraxin 3 and C1q. Eur J Immunol (2003) 1.67
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Opsonization with C1q and mannose-binding lectin targets apoptotic cells to dendritic cells. J Immunol (2004) 1.64
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The protein expression of Streptococcus pyogenes is significantly influenced by human plasma. J Proteome Res (2005) 1.55
The renal histopathological spectrum of patients with nephrotic syndrome: an analysis of 1523 patients in a single Chinese centre. Nephrol Dial Transplant (2011) 1.54
IL-10-producing macrophages preferentially clear early apoptotic cells. Blood (2006) 1.53
Experimentally induced liver metastases from colorectal cancer can be prevented by mononuclear phagocyte-mediated monoclonal antibody therapy. J Hepatol (2010) 1.52
Direct binding of C1q to apoptotic cells and cell blebs induces complement activation. Eur J Immunol (2002) 1.52
Activation of the complement system generates antibacterial peptides. Proc Natl Acad Sci U S A (2004) 1.51
Synergism between a novel chimeric lysin and oxacillin protects against infection by methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother (2010) 1.48
Functional characterization of the lectin pathway of complement in human serum. Mol Immunol (2003) 1.48
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In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner. Proc Natl Acad Sci U S A (2008) 1.44
Enzymatic characterization of the streptococcal endopeptidase, IdeS, reveals that it is a cysteine protease with strict specificity for IgG cleavage due to exosite binding. Biochemistry (2004) 1.43
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Human IgG/Fc gamma R interactions are modulated by streptococcal IgG glycan hydrolysis. PLoS One (2008) 1.37
Complement deposition in renal histopathology of patients with ANCA-associated pauci-immune glomerulonephritis. Nephrol Dial Transplant (2008) 1.37
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Streptococcal M protein: a multipotent and powerful inducer of inflammation. J Immunol (2006) 1.36
The regulator PerR is involved in oxidative stress response and iron homeostasis and is necessary for full virulence of Streptococcus pyogenes. Infect Immun (2002) 1.33
Structure of the streptococcal endopeptidase IdeS, a cysteine proteinase with strict specificity for IgG. Proc Natl Acad Sci U S A (2004) 1.32
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Structure and function of the long pentraxin PTX3 glycosidic moiety: fine-tuning of the interaction with C1q and complement activation. Biochemistry (2006) 1.32
Tubulointerstitial lesions of patients with lupus nephritis classified by the 2003 International Society of Nephrology and Renal Pathology Society system. Kidney Int (2010) 1.32
Anti-C1q autoantibodies deposit in glomeruli but are only pathogenic in combination with glomerular C1q-containing immune complexes. J Clin Invest (2004) 1.31
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A functional variant in the CFI gene confers a high risk of age-related macular degeneration. Nat Genet (2013) 1.29
Streptococcus pyogenes expressing M and M-like surface proteins are phagocytosed but survive inside human neutrophils. Cell Microbiol (2003) 1.29
ANCA-negative pauci-immune crescentic glomerulonephritis. Nat Rev Nephrol (2009) 1.29
Circulating microRNA expression profiles associated with systemic lupus erythematosus. Arthritis Rheum (2013) 1.28
IgG glycan hydrolysis by a bacterial enzyme as a therapy against autoimmune conditions. Proc Natl Acad Sci U S A (2008) 1.27
Factor B structure provides insights into activation of the central protease of the complement system. Nat Struct Mol Biol (2007) 1.27
Rapamycin specifically interferes with GM-CSF signaling in human dendritic cells, leading to apoptosis via increased p27KIP1 expression. Blood (2002) 1.26
Proteolysis and its regulation at the surface of Streptococcus pyogenes. Mol Microbiol (2002) 1.25
Myeloperoxidase is critically involved in the induction of organ damage after renal ischemia reperfusion. Am J Pathol (2007) 1.24
IgG glycan hydrolysis attenuates ANCA-mediated glomerulonephritis. J Am Soc Nephrol (2010) 1.24
alpha2-Macroglobulin-proteinase complexes protect Streptococcus pyogenes from killing by the antimicrobial peptide LL-37. J Biol Chem (2004) 1.23
Complement activation by (auto-) antibodies. Mol Immunol (2011) 1.22
Review article: Drug-induced anti-neutrophil cytoplasmic antibody-associated vasculitis. Nephrology (Carlton) (2009) 1.21
Integrin alpha3beta1, a novel receptor for alpha3(IV) noncollagenous domain and a trans-dominant Inhibitor for integrin alphavbeta3. J Biol Chem (2006) 1.20
Risk alleles in CFH and ARMS2 are independently associated with systemic complement activation in age-related macular degeneration. Ophthalmology (2011) 1.20
The membrane attack complex of complement induces caspase activation and apoptosis. Eur J Immunol (2002) 1.20
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Incidence and survival rates in Wegener's granulomatosis, microscopic polyangiitis, Churg-Strauss syndrome and polyarteritis nodosa. Rheumatology (Oxford) (2009) 1.18
Recognition and clearance of apoptotic cells: a role for complement and pentraxins. Trends Immunol (2003) 1.17
Cysteine proteinase SpeB from Streptococcus pyogenes - a potent modifier of immunologically important host and bacterial proteins. Biol Chem (2011) 1.17
Blocking of experimental arthritis by cleavage of IgG antibodies in vivo. Arthritis Rheum (2007) 1.17
Connective tissue growth factor and igf-I are produced by human renal fibroblasts and cooperate in the induction of collagen production by high glucose. Diabetes (2003) 1.16
Modified C-reactive protein might be a target autoantigen of TINU syndrome. Clin J Am Soc Nephrol (2010) 1.16
Inclusion of renal vascular lesions in the 2003 ISN/RPS system for classifying lupus nephritis improves renal outcome predictions. Kidney Int (2013) 1.15
Antibody-mediated activation of the classical pathway of complement may compensate for mannose-binding lectin deficiency. Eur J Immunol (2004) 1.15
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Crystal structure and biological implications of a bacterial albumin binding module in complex with human serum albumin. J Biol Chem (2004) 1.14
Low antibody levels against cell wall-attached proteins of Streptococcus pyogenes predispose for severe invasive disease. J Infect Dis (2004) 1.14
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Complement activation by tubular cells is mediated by properdin binding. Am J Physiol Renal Physiol (2008) 1.12
Therapeutic targeting of classical and lectin pathways of complement protects from ischemia-reperfusion-induced renal damage. Am J Pathol (2010) 1.12
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IdeS: a bacterial proteolytic enzyme with therapeutic potential. PLoS One (2008) 1.10