Published in J Am Chem Soc on May 12, 2010
Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1. PLoS Biol (2015) 2.07
The energy landscape of adenylate kinase during catalysis. Nat Struct Mol Biol (2015) 1.62
A spring-loaded release mechanism regulates domain movement and catalysis in phosphoglycerate kinase. J Biol Chem (2011) 1.10
Mechanisms of protein sequence divergence and incompatibility. PLoS Genet (2013) 0.91
An allosteric signaling pathway of human 3-phosphoglycerate kinase from force distribution analysis. PLoS Comput Biol (2014) 0.86
Near attack conformers dominate β-phosphoglucomutase complexes where geometry and charge distribution reflect those of substrate. Proc Natl Acad Sci U S A (2012) 0.86
Expression, purification, crystallization and preliminary X-ray diffraction studies of phosphoglycerate kinase from methicillin-resistant Staphylococcus aureus MRSA252. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.86
Molecular insights on pathogenic effects of mutations causing phosphoglycerate kinase deficiency. PLoS One (2012) 0.86
Crystal structures of the novel cytosolic 5'-nucleotidase IIIB explain its preference for m7GMP. PLoS One (2014) 0.84
α-Fluorophosphonates reveal how a phosphomutase conserves transition state conformation over hexose recognition in its two-step reaction. Proc Natl Acad Sci U S A (2014) 0.80
(19) F NMR and DFT Analysis Reveal Structural and Electronic Transition State Features for RhoA-Catalyzed GTP Hydrolysis. Angew Chem Int Ed Engl (2016) 0.79
A structural perspective of compensatory evolution. Curr Opin Struct Biol (2014) 0.77
Thioredoxin-dependent redox regulation of chloroplastic phosphoglycerate kinase from Chlamydomonas reinhardtii. J Biol Chem (2014) 0.77
Crystal structures of putative phosphoglycerate kinases from B. anthracis and C. jejuni. J Struct Funct Genomics (2012) 0.76
Insights into human phosphoglycerate kinase 1 deficiency as a conformational disease from biochemical, biophysical, and in vitro expression analyses. J Inherit Metab Dis (2014) 0.76
Measurement of the intrinsic variability within protein crystals: implications for sample-evaluation and data-collection strategies. Acta Crystallogr F Struct Biol Commun (2013) 0.76
Protein Stability, Folding and Misfolding in Human PGK1 Deficiency. Biomolecules (2013) 0.76
OptZyme: computational enzyme redesign using transition state analogues. PLoS One (2013) 0.75
Metal Fluorides: Tools for Structural and Computational Analysis of Phosphoryl Transfer Enzymes. Top Curr Chem (J) (2017) 0.75
(1)H, (15)N, (13)C backbone resonance assignments of human phosphoglycerate kinase in a transition state analogue complex with ADP, 3-phosphoglycerate and magnesium trifluoride. Biomol NMR Assign (2017) 0.75
Rociletinib in EGFR-mutated non-small-cell lung cancer. N Engl J Med (2015) 6.28
The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design. Nature (2006) 6.00
Structure and catalytic mechanism of the human histone methyltransferase SET7/9. Nature (2003) 4.00
Crystal structure and functional analysis of the histone methyltransferase SET7/9. Cell (2002) 2.27
Improving diffraction by humidity control: a novel device compatible with X-ray beamlines. Acta Crystallogr D Biol Crystallogr (2009) 1.73
MxCuBE: a synchrotron beamline control environment customized for macromolecular crystallography experiments. J Synchrotron Radiat (2010) 1.71
Catalytic roles for carbon-oxygen hydrogen bonding in SET domain lysine methyltransferases. J Biol Chem (2006) 1.53
Deep vein thrombosis resolution is modulated by monocyte CXCR2-mediated activity in a mouse model. Arterioscler Thromb Vasc Biol (2004) 1.49
The use of workflows in the design and implementation of complex experiments in macromolecular crystallography. Acta Crystallogr D Biol Crystallogr (2012) 1.46
Inducing phase changes in crystals of macromolecules: status and perspectives for controlled crystal dehydration. J Struct Biol (2011) 1.36
Antibiotic recognition by binuclear metallo-beta-lactamases revealed by X-ray crystallography. J Am Chem Soc (2005) 1.30
Structural and functional analysis of RNA and TAP binding to SF2/ASF. EMBO Rep (2007) 1.28
Essential role of proline isomerization in stefin B tetramer formation. J Mol Biol (2006) 1.23
The crystal structure of diadenosine tetraphosphate hydrolase from Caenorhabditis elegans in free and binary complex forms. Structure (2002) 1.21
Obligate heterodimerization of the archaeal Alba2 protein with Alba1 provides a mechanism for control of DNA packaging. Structure (2005) 1.20
Automatic processing of macromolecular crystallography X-ray diffraction data at the ESRF. J Appl Crystallogr (2013) 1.19
Polyphenol/peptide binding and precipitation. J Agric Food Chem (2002) 1.17
Determinants of the endosomal localization of sorting nexin 1. Mol Biol Cell (2005) 1.15
The residue 129 polymorphism in human prion protein does not confer susceptibility to Creutzfeldt-Jakob disease by altering the structure or global stability of PrPC. J Biol Chem (2004) 1.14
ATP analogues with modified phosphate chains and their selectivity for rat P2X2 and P2X2/3 receptors. Br J Pharmacol (2003) 1.12
A spring-loaded release mechanism regulates domain movement and catalysis in phosphoglycerate kinase. J Biol Chem (2011) 1.10
Occurrence and genetic variability of Candida parapsilosis sensu lato in Hungary. J Med Microbiol (2007) 1.10
Direct cryocooling of naked crystals: are cryoprotection agents always necessary? Acta Crystallogr D Biol Crystallogr (2011) 1.08
Turnover-based in vitro selection and evolution of biocatalysts from a fully synthetic antibody library. Nat Biotechnol (2003) 1.06
Solution structure of the helicase-interaction domain of the primase DnaG: a model for helicase activation. Structure (2005) 1.04
Effects of domain dissection on the folding and stability of the 43 kDa protein PGK probed by NMR. J Mol Biol (2003) 1.03
Structural basis of the PNRC2-mediated link between mrna surveillance and decapping. Structure (2012) 1.02
Role of phosphate chain mobility of MgATP in completing the 3-phosphoglycerate kinase catalytic site: binding, kinetic, and crystallographic studies with ATP and MgATP. Biochemistry (2004) 1.00
Cystatin forms a tetramer through structural rearrangement of domain-swapped dimers prior to amyloidogenesis. J Mol Biol (2004) 1.00
Structure and dynamics of coxsackievirus B4 2A proteinase, an enyzme involved in the etiology of heart disease. J Virol (2006) 1.00
Fast protein motions are coupled to enzyme H-transfer reactions. J Am Chem Soc (2013) 1.00
A Trojan horse transition state analogue generated by MgF3- formation in an enzyme active site. Proc Natl Acad Sci U S A (2006) 1.00
Definable equilibrium states in the folding of human prion protein. Biochemistry (2005) 0.99
Biochemical, crystallographic, and mutagenic characterization of hint, the AMP-lysine hydrolase, with novel substrates and inhibitors. J Biol Chem (2004) 0.99
Simultaneously enhancing spectral resolution and sensitivity in heteronuclear correlation NMR spectroscopy. Angew Chem Int Ed Engl (2013) 0.99
Multiple forms of copper (II) co-ordination occur throughout the disordered N-terminal region of the prion protein at pH 7.4. Biochem J (2006) 0.98
Anionic charge is prioritized over geometry in aluminum and magnesium fluoride transition state analogs of phosphoryl transfer enzymes. J Am Chem Soc (2008) 0.97
Donor-cell myelodysplastic syndrome developing 13 years after marrow grafting for aplastic anemia. Cancer Genet Cytogenet (2003) 0.97
Trapping of the thioacylglyceraldehyde-3-phosphate dehydrogenase intermediate from Bacillus stearothermophilus. Direct evidence for a flip-flop mechanism. J Biol Chem (2008) 0.96
Atomic details of near-transition state conformers for enzyme phosphoryl transfer revealed by MgF-3 rather than by phosphoranes. Proc Natl Acad Sci U S A (2010) 0.96
Structure and mechanism of imidazoleglycerol-phosphate dehydratase. Structure (2005) 0.94
Reprogramming of Escherichia coli K-12 metabolism during the initial phase of transition from an anaerobic to a micro-aerobic environment. PLoS One (2011) 0.94
Folding kinetics of the human prion protein probed by temperature jump. Proc Natl Acad Sci U S A (2009) 0.94
Increasing the diffraction limit and internal order of a membrane protein crystal by dehydration. J Struct Biol (2003) 0.93
Recent progress in robot-based systems for crystallography and their contribution to drug discovery. Expert Opin Drug Discov (2013) 0.92
Chemical polysialylation of human recombinant butyrylcholinesterase delivers a long-acting bioscavenger for nerve agents in vivo. Proc Natl Acad Sci U S A (2013) 0.92
A reassessment of copper(II) binding in the full-length prion protein. Biochem J (2006) 0.92
Cryogenic and laser photoexcitation studies identify multiple roles for active site residues in the light-driven enzyme protochlorophyllide oxidoreductase. J Biol Chem (2009) 0.92
Measurement of energy landscape roughness of folded and unfolded proteins. Proc Natl Acad Sci U S A (2012) 0.91
Pharmacological chaperone for the structured domain of human prion protein. Proc Natl Acad Sci U S A (2010) 0.90
Selectivity of kinases on the activation of tenofovir, an anti-HIV agent. Eur J Pharm Sci (2012) 0.89
A combinatorial selective labeling method for the assignment of backbone amide NMR resonances. J Am Chem Soc (2004) 0.89
Measurement of the equilibrium relative humidity for common precipitant concentrations: facilitating controlled dehydration experiments. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.88
The mechanism of amyloid-fibril formation by stefin B: temperature and protein concentration dependence of the rates. Proteins (2009) 0.87
Conformational properties of beta-PrP. J Biol Chem (2009) 0.87
Near attack conformers dominate β-phosphoglucomutase complexes where geometry and charge distribution reflect those of substrate. Proc Natl Acad Sci U S A (2012) 0.86
Interaction of human 3-phosphoglycerate kinase with its two substrates: is substrate antagonism a kinetic advantage? J Mol Biol (2011) 0.86
Exclusion of the native alpha-helix from the amyloid fibrils of a mixed alpha/beta protein. J Mol Biol (2007) 0.86
Catalysis by Glomerella cingulata cutinase requires conformational cycling between the active and inactive states of its catalytic triad. J Mol Biol (2008) 0.86
A dose-escalation study of SAR3419, an anti-CD19 antibody maytansinoid conjugate, administered by intravenous infusion once weekly in patients with relapsed/refractory B-cell non-Hodgkin lymphoma. Clin Cancer Res (2013) 0.85
Determination of the microscopic equilibrium dissociation constants for risedronate and its analogues reveals two distinct roles for the nitrogen atom in nitrogen-containing bisphosphonate drugs. J Med Chem (2008) 0.85
Substrate-induced double sided H-bond network as a means of domain closure in 3-phosphoglycerate kinase. FEBS Lett (2006) 0.85
Communication between the nucleotide site and the main molecular hinge of 3-phosphoglycerate kinase. Biochemistry (2008) 0.85
Substrate-assisted movement of the catalytic Lys 215 during domain closure: site-directed mutagenesis studies of human 3-phosphoglycerate kinase. Biochemistry (2005) 0.85
Role of pathogenic oral flora in postoperative pneumonia following brain surgery. BMC Infect Dis (2009) 0.85
Evaluation of sexuality, health-related quality-of-life and depression in advanced cancer patients: a prospective study in a Phase I clinical trial unit of predominantly targeted anticancer drugs. Eur J Cancer (2012) 0.85
When simple sequence comparison fails: the cryptic case of the shared domains of the bacterial replication initiation proteins DnaB and DnaD. Nucleic Acids Res (2010) 0.85
The Ighmbp2 helicase structure reveals the molecular basis for disease-causing mutations in DMSA1. Nucleic Acids Res (2012) 0.84
The H187R mutation of the human prion protein induces conversion of recombinant prion protein to the PrP(Sc)-like form. Biochemistry (2010) 0.84
Nucleotide binding to pig muscle 3-phosphoglycerate kinase in the crystal and in solution: relationship between substrate antagonism and interdomain communication. Biochemistry (2002) 0.84
Exposure to 50 Hz magnetic field in apartment buildings with built-in transformer stations in Hungary. Radiat Prot Dosimetry (2008) 0.84
Correlation between conformational stability of the ternary enzyme-substrate complex and domain closure of 3-phosphoglycerate kinase. FEBS J (2005) 0.83
Analysis of the catalytic and binding residues of the diadenosine tetraphosphate pyrophosphohydrolase from Caenorhabditis elegans by site-directed mutagenesis. J Biol Chem (2002) 0.83