Rare deletions at 16p13.11 predispose to a diverse spectrum of sporadic epilepsy syndromes.

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Published in Am J Hum Genet on April 15, 2010

Authors

Erin L Heinzen1, Rodney A Radtke, Thomas J Urban, Gianpiero L Cavalleri, Chantal Depondt, Anna C Need, Nicole M Walley, Paola Nicoletti, Dongliang Ge, Claudia B Catarino, John S Duncan, Dalia Kasperaviciūte, Sarah K Tate, Luis O Caboclo, Josemir W Sander, Lisa Clayton, Kristen N Linney, Kevin V Shianna, Curtis E Gumbs, Jason Smith, Kenneth D Cronin, Jessica M Maia, Colin P Doherty, Massimo Pandolfo, David Leppert, Lefkos T Middleton, Rachel A Gibson, Michael R Johnson, Paul M Matthews, David Hosford, Reetta Kälviäinen, Kai Eriksson, Anne-Mari Kantanen, Thomas Dorn, Jörg Hansen, Günter Krämer, Bernhard J Steinhoff, Heinz-Gregor Wieser, Dominik Zumsteg, Marcos Ortega, Nicholas W Wood, Julie Huxley-Jones, Mohamad Mikati, William B Gallentine, Aatif M Husain, Patrick G Buckley, Ray L Stallings, Mihai V Podgoreanu, Norman Delanty, Sanjay M Sisodiya, David B Goldstein

Author Affiliations

1: Center for Human Genome Variation, School of Medicine, Duke University, Durham, NC 27708, USA.

Associated clinical trials:

Targeting a Genetic Mutation in Glycine Metabolism With D-cycloserine (DCS) | NCT02304432

Neurobiology of a Mutation in Glycine Metabolism in Psychotic Disorders | NCT01720316

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