Published in Crit Care Med on June 01, 2010
Retinol binding protein: marker for insulin resistance and inflammation postburn? JPEN J Parenter Enteral Nutr (2011) 1.41
The Sick and the Weak: Neuropathies/Myopathies in the Critically Ill. Physiol Rev (2015) 1.20
Burns: an update on current pharmacotherapy. Expert Opin Pharmacother (2012) 0.95
The impact of severe burns on skeletal muscle mitochondrial function. Burns (2013) 0.84
Cardiovascular Dysfunction Following Burn Injury: What We Have Learned from Rat and Mouse Models. Int J Mol Sci (2016) 0.82
Timing of insulin therapy affects the inflammatory response in endotoxemic rats. Inflammation (2012) 0.79
Intensive insulin therapy: are burns different? Crit Care Med (2010) 0.77
Alcohol Modulation of the Postburn Hepatic Response. J Burn Care Res (2015) 0.75
Management of burns in the elderly. Ann Burns Fire Disasters (2016) 0.75
Intensive insulin therapy in critically ill patients. N Engl J Med (2001) 40.00
Intensive insulin therapy in the medical ICU. N Engl J Med (2006) 22.37
Mitochondrial dysfunction in the elderly: possible role in insulin resistance. Science (2003) 11.39
Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes (2002) 10.49
Effect of an intensive glucose management protocol on the mortality of critically ill adult patients. Mayo Clin Proc (2004) 7.03
Insulin-dependent regulation of insulin receptor concentrations: a direct demonstration in cell culture. Proc Natl Acad Sci U S A (1974) 5.73
Mechanisms of fatty acid-induced inhibition of glucose uptake. J Clin Invest (1994) 5.12
Catecholamines: mediator of the hypermetabolic response to thermal injury. Ann Surg (1974) 4.48
Interaction between glucose and free fatty acid metabolism in human skeletal muscle. J Clin Invest (1993) 2.68
Determinants of skeletal muscle catabolism after severe burn. Ann Surg (2000) 2.56
Improving glycemic control in the cardiothoracic intensive care unit: clinical experience in two hospital settings. J Cardiothorac Vasc Anesth (2004) 2.22
Effects of different hematocrit levels on glucose measurements with handheld meters for point-of-care testing. Arch Pathol Lab Med (2000) 2.17
Effect of severe burn injury on substrate cycling by glucose and fatty acids. N Engl J Med (1987) 1.90
New methods for calculating metabolic rate with special reference to protein metabolism. 1949. Nutrition (1992) 1.84
Comparison of point-of-care and laboratory glucose analysis in critically ill patients. Am J Crit Care (2007) 1.80
Protection of hepatocyte mitochondrial ultrastructure and function by strict blood glucose control with insulin in critically ill patients. Lancet (2005) 1.78
Effect of sustained physiologic hyperinsulinaemia and hyperglycaemia on insulin secretion and insulin sensitivity in man. Diabetologia (1994) 1.73
A comparison of blood glucose meters in Australia. Diabetes Res Clin Pract (2005) 1.66
Mechanisms of insulin resistance following injury. Ann Surg (1982) 1.64
Stimulation of muscle protein synthesis by long-term insulin infusion in severely burned patients. Ann Surg (1995) 1.63
Post burn muscle wasting and the effects of treatments. Int J Biochem Cell Biol (2005) 1.62
Glucose metabolism in severely burned patients. Metabolism (1979) 1.57
Burn injury causes mitochondrial dysfunction in skeletal muscle. Proc Natl Acad Sci U S A (2005) 1.46
Target ranges and the apparent compliance with tight glycaemic control. Anaesthesia (2006) 1.43
The role of the carnitine system in human metabolism. Ann N Y Acad Sci (2004) 1.42
Impact of tight glycemic control in severely burned children. J Trauma (2005) 1.40
Production of insulin resistance by hyperinsulinaemia in man. Diabetologia (1985) 1.36
Malonyl coenzyme A and the regulation of functional carnitine palmitoyltransferase-1 activity and fat oxidation in human skeletal muscle. J Clin Invest (2002) 1.31
Effects of insulin incubation on insulin binding, glucose transport, and insulin degradation by isolated rat adipocytes. Evidence for hormone-induced desensitization at the receptor and postreceptor level. J Clin Invest (1980) 1.26
Epinephrine plasma thresholds for lipolytic effects in man: measurements of fatty acid transport with [l-13C]palmitic acid. J Clin Invest (1981) 1.24
Indirect effect of insulin to suppress endogenous glucose production is dominant, even with hyperglucagonemia. J Clin Invest (1997) 1.22
Implementing tight glucose control after coronary artery bypass surgery. Ann Thorac Surg (2005) 1.18
PPAR-alpha agonism improves whole body and muscle mitochondrial fat oxidation, but does not alter intracellular fat concentrations in burn trauma children in a randomized controlled trial. Nutr Metab (Lond) (2007) 1.09
Insulin resistance in cirrhosis: prolonged reduction of hyperinsulinemia normalizes insulin sensitivity. Hepatology (1998) 1.06
Human mitochondrial oxidative capacity is acutely impaired after burn trauma. Am J Surg (2008) 1.04
Intensive insulin treatment in critically ill trauma patients normalizes glucose by reducing endogenous glucose production. J Clin Endocrinol Metab (2004) 1.00
Influence of glucose kinetics on plasma lactate concentration and energy expenditure in severely burned patients. J Trauma (2000) 0.99
Cardiac mitochondrial damage and loss of ROS defense after burn injury: the beneficial effects of antioxidant therapy. J Appl Physiol (1985) (2006) 0.97
Insulin therapy in burn patients does not contribute to hepatic triglyceride production. J Clin Invest (1998) 0.96
Assessment of methods for improving tracer estimation of non-steady-state rate of appearance. J Appl Physiol (1985) (1999) 0.95
Glucose metabolism in children during the first day after burn injury. Arch Emerg Med (1990) 0.93
The systemic stress response to thermal injury in children. Clin Endocrinol (Oxf) (1998) 0.92
Insulin resistance, secretion and breakdown are increased 9 months following severe burn injury. Burns (2008) 0.91
Desensitization of hepatoma cells to insulin action. Evidence for a post-receptor mechanism. J Biol Chem (1981) 0.90
Resistance to exercise-induced increase in glucose uptake during hyperinsulinemia in insulin-resistant skeletal muscle of patients with type 1 diabetes. Diabetes (2001) 0.85
The effects of thermal injury on mitochondrial oxygen consumption and the glycerol phosphate shuttle. Metabolism (1994) 0.84
Comparison of insulin sensitivity, clearance, and secretion estimates using euglycemic and hyperglycemic clamps in children. J Clin Endocrinol Metab (2002) 0.83
Hunterian Lecture: Insulin resistance in human sepsis: implications for the nutritional and metabolic care of the critically ill surgical patient. Ann R Coll Surg Engl (2004) 0.82
Burn injury and increased glucose production. J Trauma (1979) 0.79
Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci U S A (2013) 16.74
A genomic storm in critically injured humans. J Exp Med (2011) 6.67
Pathophysiologic response to severe burn injury. Ann Surg (2008) 3.73
NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis. J Clin Invest (2003) 3.69
Application of genome-wide expression analysis to human health and disease. Proc Natl Acad Sci U S A (2005) 3.49
Resistance exercise increases AMPK activity and reduces 4E-BP1 phosphorylation and protein synthesis in human skeletal muscle. J Physiol (2006) 3.08
A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly. Am J Physiol Endocrinol Metab (2006) 2.80
American Burn Association consensus conference to define sepsis and infection in burns. J Burn Care Res (2007) 2.71
Hydrogen sulfide is an endogenous stimulator of angiogenesis. Proc Natl Acad Sci U S A (2009) 2.66
Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults. Am J Clin Nutr (2003) 2.65
Long-term persistance of the pathophysiologic response to severe burn injury. PLoS One (2011) 2.58
Amino acid ingestion improves muscle protein synthesis in the young and elderly. Am J Physiol Endocrinol Metab (2003) 2.41
Human muscle protein synthesis is modulated by extracellular, not intramuscular amino acid availability: a dose-response study. J Physiol (2003) 2.39
Protein, weight management, and satiety. Am J Clin Nutr (2008) 2.34
Cytokine expression profile over time in severely burned pediatric patients. Shock (2006) 2.33
Three different neutrophil subsets exhibited in mice with different susceptibilities to infection by methicillin-resistant Staphylococcus aureus. Immunity (2004) 2.29
Leucine-enriched essential amino acid and carbohydrate ingestion following resistance exercise enhances mTOR signaling and protein synthesis in human muscle. Am J Physiol Endocrinol Metab (2007) 2.26
CCL17 and IL-10 as effectors that enable alternatively activated macrophages to inhibit the generation of classically activated macrophages. J Immunol (2004) 2.25
Testosterone administration to older men improves muscle function: molecular and physiological mechanisms. Am J Physiol Endocrinol Metab (2002) 2.24
Effect of β-hydroxy-β-methylbutyrate (HMB) on lean body mass during 10 days of bed rest in older adults. Clin Nutr (2013) 2.17
Insulin resistance of muscle protein metabolism in aging. FASEB J (2006) 2.17
Aging is associated with diminished accretion of muscle proteins after the ingestion of a small bolus of essential amino acids. Am J Clin Nutr (2005) 2.15
Preclinical evaluation of epinephrine nebulization to reduce airway hyperemia and improve oxygenation after smoke inhalation injury. Crit Care Med (2011) 2.10
Long-term posttraumatic stress symptoms vary inversely with early opiate dosing in children recovering from serious burns: effects durable at 4 years. J Trauma Acute Care Surg (2014) 2.03
Role of mitochondrial inner membrane permeabilization in necrotic cell death, apoptosis, and autophagy. Antioxid Redox Signal (2002) 2.03
Impaired zinc and copper status in children with burn injuries: need to reassess nutritional requirements. Burns (2005) 1.98
Burn size determines the inflammatory and hypermetabolic response. Crit Care (2007) 1.97
A novel animal model of sepsis after acute lung injury in sheep. Crit Care Med (2002) 1.95
Hepatitis C virus core protein, cytochrome P450 2E1, and alcohol produce combined mitochondrial injury and cytotoxicity in hepatoma cells. Gastroenterology (2005) 1.95
Inhibition of the mitochondrial permeability transition by the nonimmunosuppressive cyclosporin derivative NIM811. Mol Pharmacol (2002) 1.95
Role of dietary protein in the sarcopenia of aging. Am J Clin Nutr (2008) 1.91
Cyclophilin D as a drug target. Curr Med Chem (2003) 1.87
Glucose control in severely thermally injured pediatric patients: what glucose range should be the target? Ann Surg (2010) 1.78
Blood transfusions are associated with increased risk for development of sepsis in severely burned pediatric patients. Crit Care Med (2007) 1.77
Differential requirement for c-Jun NH2-terminal kinase in TNFalpha- and Fas-mediated apoptosis in hepatocytes. FASEB J (2004) 1.76
Synthesis of vitamin D in skin after burns. Lancet (2004) 1.75
Combination of recombinant human growth hormone and propranolol decreases hypermetabolism and inflammation in severely burned children. Pediatr Crit Care Med (2008) 1.73
Primary cirrhotic hepatocytes resist TGFbeta-induced apoptosis through a ROS-dependent mechanism. J Hepatol (2004) 1.72
Abnormal insulin sensitivity persists up to three years in pediatric patients post-burn. J Clin Endocrinol Metab (2009) 1.71
A moderate serving of high-quality protein maximally stimulates skeletal muscle protein synthesis in young and elderly subjects. J Am Diet Assoc (2009) 1.70
Combined neuronal and inducible nitric oxide synthase inhibition in ovine acute lung injury. Crit Care Med (2009) 1.68
Temporal cytokine profiles in severely burned patients: a comparison of adults and children. Mol Med (2008) 1.67
Morbidity and survival probability in burn patients in modern burn care. Crit Care Med (2015) 1.67
Hyperglycemia exacerbates muscle protein catabolism in burn-injured patients. Crit Care Med (2002) 1.66
Essential amino acids and muscle protein recovery from resistance exercise. Am J Physiol Endocrinol Metab (2002) 1.64
Mitochondrial permeability transition in the switch from necrotic to apoptotic cell death in ischemic rat hepatocytes. Gastroenterology (2003) 1.63
Intramuscular and liver triglycerides are increased in the elderly. J Clin Endocrinol Metab (2004) 1.62
Longitudinal assessment of Integra in primary burn management: a randomized pediatric clinical trial. Crit Care Med (2007) 1.62
Post burn muscle wasting and the effects of treatments. Int J Biochem Cell Biol (2005) 1.62
Insulin treatment improves the systemic inflammatory reaction to severe trauma. Ann Surg (2004) 1.61
The influence of age and gender on resting energy expenditure in severely burned children. Ann Surg (2006) 1.60
Influence of systemic inflammatory response syndrome on host resistance against bacterial infections. Crit Care Med (2004) 1.59
Serum cytokine differences in severely burned children with and without sepsis. Shock (2007) 1.59
The leading causes of death after burn injury in a single pediatric burn center. Crit Care (2009) 1.59
Airway obstruction in sheep with burn and smoke inhalation injuries. Am J Respir Cell Mol Biol (2003) 1.58
Benchmarking outcomes in the critically injured burn patient. Ann Surg (2014) 1.58
Prediction of mortality from catastrophic burns in children. Lancet (2003) 1.58
Modulation of types I and II acute phase reactants with insulin-like growth factor-1/binding protein-3 complex in severely burned children. Crit Care Med (2002) 1.58
Aging does not impair the anabolic response to a protein-rich meal. Am J Clin Nutr (2007) 1.58
Hypoglycemia is associated with increased postburn morbidity and mortality in pediatric patients. Crit Care Med (2014) 1.58
Emerging infections in burns. Surg Infect (Larchmt) (2009) 1.57
Inhibition of neuronal nitric oxide synthase in ovine model of acute lung injury. Crit Care Med (2009) 1.57
Atrophy and impaired muscle protein synthesis during prolonged inactivity and stress. J Clin Endocrinol Metab (2006) 1.56
Skin nitric oxide and its metabolites are increased in nonburned skin after thermal injuries. Shock (2004) 1.56
Differential stimulation of muscle protein synthesis in elderly humans following isocaloric ingestion of amino acids or whey protein. Exp Gerontol (2005) 1.53
Rapid Expectation Adaptation during Syntactic Comprehension. PLoS One (2013) 1.53
Intensive insulin therapy in severely burned pediatric patients: a prospective randomized trial. Am J Respir Crit Care Med (2010) 1.53
Continuous nebulized albuterol attenuates acute lung injury in an ovine model of combined burn and smoke inhalation. Crit Care Med (2006) 1.52
The effect of growth hormone on gut mucosal homeostasis and cellular mediators after severe trauma. J Surg Res (2005) 1.52
Evidence supporting a role of glucocorticoids in short-term bone loss in burned children. Osteoporos Int (2004) 1.52
Stable isotope tracer dilution for quantifying very low-density lipoprotein-triacylglycerol kinetics in man. Clin Nutr (2004) 1.49
Body composition changes with time in pediatric burn patients. J Trauma (2006) 1.49
Acute response of net muscle protein balance reflects 24-h balance after exercise and amino acid ingestion. Am J Physiol Endocrinol Metab (2002) 1.48
A genomic score prognostic of outcome in trauma patients. Mol Med (2009) 1.48
Ingestion of casein and whey proteins result in muscle anabolism after resistance exercise. Med Sci Sports Exerc (2004) 1.47
Pivotal advance: glycyrrhizin restores the impaired production of beta-defensins in tissues surrounding the burn area and improves the resistance of burn mice to Pseudomonas aeruginosa wound infection. J Leukoc Biol (2009) 1.46
Isoflurane but not mechanical ventilation promotes extravascular fluid accumulation during crystalloid volume loading. Anesthesiology (2003) 1.46
Amino acid supplementation increases lean body mass, basal muscle protein synthesis, and insulin-like growth factor-I expression in older women. J Clin Endocrinol Metab (2009) 1.45
IGF-I gene transfer effects on inflammatory elements present after thermal trauma. Am J Physiol Regul Integr Comp Physiol (2003) 1.43
Essential amino acid and carbohydrate supplementation ameliorates muscle protein loss in humans during 28 days bedrest. J Clin Endocrinol Metab (2004) 1.43
Beneficial effects of concomitant neuronal and inducible nitric oxide synthase inhibition in ovine burn and inhalation injury. Shock (2011) 1.42
The effect of hepatocyte growth factor on gut mucosal apoptosis and proliferation, and cellular mediators after severe trauma. Surgery (2005) 1.42
The effects of oxandrolone and exercise on muscle mass and function in children with severe burns. Pediatrics (2006) 1.42
The association between fluid administration and outcome following major burn: a multicenter study. Ann Surg (2007) 1.41