Published in BMC Bioinformatics on April 16, 2010
Plasma free amino acid profiling of five types of cancer patients and its application for early detection. PLoS One (2011) 1.73
Possibility of multivariate function composed of plasma amino acid profiles as a novel screening index for non-small cell lung cancer: a case control study. BMC Cancer (2010) 1.31
Analytical methods in untargeted metabolomics: state of the art in 2015. Front Bioeng Biotechnol (2015) 1.08
Review of mass spectrometry-based metabolomics in cancer research. Cancer Epidemiol Biomarkers Prev (2013) 1.03
The significance and robustness of a plasma free amino acid (PFAA) profile-based multiplex function for detecting lung cancer. BMC Cancer (2013) 0.87
Use of Charged Nanoparticles in NMR-Based Metabolomics for Spectral Simplification and Improved Metabolite Identification. Anal Chem (2015) 0.86
-The advancement of biomarker-based diagnostic tools for ovarian, breast, and pancreatic cancer through the use of urine as an analytical biofluid. Int J Biol Markers (2011) 0.80
A dried blood spot mass spectrometry metabolomic approach for rapid breast cancer detection. Onco Targets Ther (2016) 0.79
Differential distribution improves gene selection stability and has competitive classification performance for patient survival. Nucleic Acids Res (2016) 0.75
A characteristic biosignature for discrimination of gastric cancer from healthy population by high throughput GC-MS analysis. Oncotarget (2016) 0.75
A common open representation of mass spectrometry data and its application to proteomics research. Nat Biotechnol (2004) 11.42
Metabolomics--the link between genotypes and phenotypes. Plant Mol Biol (2002) 11.36
MZmine: toolbox for processing and visualization of mass spectrometry based molecular profile data. Bioinformatics (2006) 5.38
Processing methods for differential analysis of LC/MS profile data. BMC Bioinformatics (2005) 3.21
A comprehensive urinary metabolomic approach for identifying kidney cancerr. Anal Biochem (2007) 3.14
Identification of diagnostic markers for tuberculosis by proteomic fingerprinting of serum. Lancet (2006) 2.96
Mass spectrometry-based metabolic profiling reveals different metabolite patterns in invasive ovarian carcinomas and ovarian borderline tumors. Cancer Res (2006) 2.68
Discovery and validation of new protein biomarkers for urothelial cancer: a prospective analysis. Lancet Oncol (2006) 2.29
Urine metabolomics analysis for kidney cancer detection and biomarker discovery. Mol Cell Proteomics (2008) 1.78
Influence of acute phytochemical intake on human urinary metabolomic profiles. Am J Clin Nutr (2007) 1.29
Serum proteome profiling detects myelodysplastic syndromes and identifies CXC chemokine ligands 4 and 7 as markers for advanced disease. Proc Natl Acad Sci U S A (2007) 1.20
Profiles of metabolites and gene expression in rats with chemically induced hepatic necrosis. Toxicol Pathol (2005) 1.06
Metabonomics evaluations of age-related changes in the urinary compositions of male Sprague Dawley rats and effects of data normalization methods on statistical and quantitative analysis. BMC Bioinformatics (2007) 0.94
Urine metabolites reflect time-dependent effects of cyclosporine and sirolimus on rat kidney function. Chem Res Toxicol (2009) 0.90
Prediction of acute cellular renal allograft rejection by urinary metabolomics using MALDI-FTMS. J Proteome Res (2008) 0.84
Quantitative determination of urine proteins: a rapid, noninvasive, sensitive, and inexpensive method to monitor renal grafts. Transplant Proc (1995) 0.80
Network-based classification of breast cancer metastasis. Mol Syst Biol (2007) 12.18
Antiretroviral drug exposure in the female genital tract: implications for oral pre- and post-exposure prophylaxis. AIDS (2007) 4.89
Inferring pathway activity toward precise disease classification. PLoS Comput Biol (2008) 3.48
Phytochromes promote seedling light responses by inhibiting four negatively-acting phytochrome-interacting factors. Proc Natl Acad Sci U S A (2009) 2.61
Genome-wide analysis of genes targeted by PHYTOCHROME INTERACTING FACTOR 3-LIKE5 during seed germination in Arabidopsis. Plant Cell (2009) 2.44
Elevated urinary 8-isoprostaglandin F(2alpha) in females with Graves' hyperthyroidism. Prostaglandins Leukot Essent Fatty Acids (2004) 2.04
A feature-based approach to modeling protein-protein interaction hot spots. Nucleic Acids Res (2009) 1.41
Compound identification using partial and semipartial correlations for gas chromatography-mass spectrometry data. Anal Chem (2012) 1.34
Modularized learning of genetic interaction networks from biological annotations and mRNA expression data. Bioinformatics (2005) 1.33
Optogenetic mimicry of the transient activation of dopamine neurons by natural reward is sufficient for operant reinforcement. PLoS One (2012) 1.32
Mass spectrometry based metabolomic approaches in urinary biomarker study of women's cancers. Clin Chim Acta (2008) 1.27
A method of finding optimal weight factors for compound identification in gas chromatography-mass spectrometry. Bioinformatics (2012) 1.27
MetSign: a computational platform for high-resolution mass spectrometry-based metabolomics. Anal Chem (2011) 1.19
Genetic Effects of FTO and MC4R Polymorphisms on Body Mass in Constitutional Types. Evid Based Complement Alternat Med (2011) 1.14
SNP@Ethnos: a database of ethnically variant single-nucleotide polymorphisms. Nucleic Acids Res (2006) 1.14
A protein interaction network associated with asthma. J Theor Biol (2008) 1.14
Dynamic changes in DNA methylation and hydroxymethylation when hES cells undergo differentiation toward a neuronal lineage. Hum Mol Genet (2013) 1.08
Regression trees for regulatory element identification. Bioinformatics (2004) 1.07
MetPP: a computational platform for comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry-based metabolomics. Bioinformatics (2013) 1.06
Mathematical modeling of translation initiation for the estimation of its efficiency to computationally design mRNA sequences with desired expression levels in prokaryotes. BMC Syst Biol (2010) 1.04
Combining tissue transcriptomics and urine metabolomics for breast cancer biomarker identification. Bioinformatics (2009) 1.03
RBSDesigner: software for designing synthetic ribosome binding sites that yields a desired level of protein expression. Bioinformatics (2010) 1.03
Detecting clusters of different geometrical shapes in microarray gene expression data. Bioinformatics (2005) 1.03
Building the process-drug-side effect network to discover the relationship between biological processes and side effects. BMC Bioinformatics (2011) 1.00
Patome: a database server for biological sequence annotation and analysis in issued patents and published patent applications. Nucleic Acids Res (2006) 0.98
The antistress effect of ginseng total saponin and ginsenoside Rg3 and Rb1 evaluated by brain polyamine level under immobilization stress. Pharmacol Res (2006) 0.98
Comparative studies on level of androgens in hair and plasma with premature male-pattern baldness. J Dermatol Sci (2004) 0.96
Protein comparison at the domain architecture level. BMC Bioinformatics (2009) 0.96
Smith-Waterman peak alignment for comprehensive two-dimensional gas chromatography-mass spectrometry. BMC Bioinformatics (2011) 0.95
DAhunter: a web-based server that identifies homologous proteins by comparing domain architecture. Nucleic Acids Res (2008) 0.94
Analysis of AML genes in dysregulated molecular networks. BMC Bioinformatics (2009) 0.93
Specificity of molecular interactions in transient protein-protein interaction interfaces. Proteins (2006) 0.93
Evaluation of urinary nucleosides in breast cancer patients before and after tumor removal. Clin Biochem (2009) 0.91
Up-regulation of BLT2 is critical for the survival of bladder cancer cells. Exp Mol Med (2011) 0.91
Density-induced support vector data description. IEEE Trans Neural Netw (2007) 0.91
PLPD: reliable protein localization prediction from imbalanced and overlapped datasets. Nucleic Acids Res (2006) 0.90
Rapid and sensitive determination of sertraline in human plasma using gas chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci (2002) 0.89
Shotgun lipidomics for candidate biomarkers of urinary phospholipids in prostate cancer. Anal Bioanal Chem (2010) 0.89
Architecture of basic building blocks in protein and domain structural interaction networks. Bioinformatics (2004) 0.89
Caspase-7 mediated cleavage of proteasome subunits during apoptosis. Biochem Biophys Res Commun (2007) 0.89
Speed estimation from a tri-axial accelerometer using neural networks. Conf Proc IEEE Eng Med Biol Soc (2007) 0.89
Analysis of polyamines as carbamoyl derivatives in urine and serum by liquid chromatography-tandem mass spectrometry. Biomed Chromatogr (2008) 0.88
Comparison of pathways associated with hepatitis B- and C-infected hepatocellular carcinoma using pathway-based class discrimination method. Genomics (2012) 0.87
Validated quantification for selective cellular uptake of ginsenosides on MCF-7 human breast cancer cells by liquid chromatography-mass spectrometry. Anal Bioanal Chem (2010) 0.86
The association of Alu repeats with the generation of potential AU-rich elements (ARE) at 3' untranslated regions. BMC Genomics (2004) 0.86
Identification of temporal association rules from time-series microarray data sets. BMC Bioinformatics (2009) 0.85
Determination of phytoestrogens in traditional medicinal herbs using gas chromatography--mass spectrometry. J Nutr Biochem (2004) 0.85
A rapid and sensitive method for quantitation of nucleosides in human urine using liquid chromatography/mass spectrometry with direct urine injection. Rapid Commun Mass Spectrom (2004) 0.85
Gonadotropin-releasing hormone (GnRH) and GnRH receptor in bladder cancer epithelia and GnRH effect on bladder cancer cell proliferation. Urol Int (2008) 0.85
A method to improve protein subcellular localization prediction by integrating various biological data sources. BMC Bioinformatics (2009) 0.85
Alteration of plasma total F2-isoprostanes before and after hemodialysis in end-stage renal disease patients. Prostaglandins Leukot Essent Fatty Acids (2004) 0.85
Quantitative metabolic profiling of 21 endogenous corticosteroids in urine by liquid chromatography-triple quadrupole-mass spectrometry. Anal Chim Acta (2008) 0.85
Metabolomic approach to evaluate the toxicological effects of nonylphenol with rat urine. Anal Chem (2007) 0.85
Simultaneous measurement of urinary polyols using gas chromatography/mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci (2005) 0.84
bZIPDB: a database of regulatory information for human bZIP transcription factors. BMC Genomics (2007) 0.84
Simultaneous determination of anabolic steroids and synthetic hormones in meat by freezing-lipid filtration, solid-phase extraction and gas chromatography-mass spectrometry. J Chromatogr A (2005) 0.84
Compound identification in GC-MS by simultaneously evaluating the mass spectrum and retention index. Analyst (2014) 0.84
AsiDesigner: exon-based siRNA design server considering alternative splicing. Nucleic Acids Res (2008) 0.83
Comparative study of concentration of isoflavones and lignans in plasma and prostatic tissues of normal control and benign prostatic hyperplasia. Yonsei Med J (2002) 0.83
Capillary electrophoretic competitive immunoassay with laser-induced fluorescence detection for methionine-enkephalin. J Chromatogr A (2005) 0.83
Gas chromatography-mass spectrometry-based simultaneous quantitative analytical method for urinary oxysterols and bile acids in rats. Anal Biochem (2010) 0.83
Relative quantitation of restriction fragment length polymorphic DNAs via DNA melting analysis provides an effective way to determine allele frequencies. Genomics (2009) 0.83
Relations between toxicity and altered tissue distribution and urinary excretion of nicotine, cotinine, and hydroxycotinine after chronic oral administration of nicotine in rats. Drug Chem Toxicol (2010) 0.83
Discovery of common urinary biomarkers for hepatotoxicity induced by carbon tetrachloride, acetaminophen and methotrexate by mass spectrometry-based metabolomics. J Appl Toxicol (2011) 0.82
Rule-based multi-scale simulation for drug effect pathway analysis. BMC Med Inform Decis Mak (2013) 0.82
Prediction of extracellular matrix proteins based on distinctive sequence and domain characteristics. J Comput Biol (2010) 0.82
Database-dependent metabolite profiling focused on steroid and fatty acid derivatives using high-temperature gas chromatography-mass spectrometry. Clin Chim Acta (2010) 0.82
H-CORE: enabling genome-scale Bayesian analysis of biological systems without prior knowledge. Biosystems (2006) 0.82
Discovering context-specific relationships from biological literature by using multi-level context terms. BMC Med Inform Decis Mak (2012) 0.82
Social deficits in the AY-9944 mouse model of atypical absence epilepsy. Behav Brain Res (2012) 0.82
Direct determination of nucleosides in the urine of patients with breast cancer using column-switching liquid chromatography-tandem mass spectrometry. Biomed Chromatogr (2006) 0.82
Generation and application of drug indication inference models using typed network motif comparison analysis. BMC Med Inform Decis Mak (2013) 0.81
CaGe: A Web-Based Cancer Gene Annotation System for Cancer Genomics. Genomics Inform (2012) 0.81
MKEM: a Multi-level Knowledge Emergence Model for mining undiscovered public knowledge. BMC Bioinformatics (2010) 0.81
Heat-map visualization of gas chromatography-mass spectrometry based quantitative signatures on steroid metabolism. J Am Soc Mass Spectrom (2009) 0.81
Increased urinary level of oxidized nucleosides in patients with mild-to-moderate Alzheimer's disease. Clin Biochem (2007) 0.81
Expression and activation of matrix metalloproteinase-9 and NADPH oxidase in tissues and plasma of experimental autoimmune encephalomyelitis in mice. Exp Toxicol Pathol (2010) 0.81
Cytochrome P450-mediated metabolic alterations in preeclampsia evaluated by quantitative steroid signatures. J Steroid Biochem Mol Biol (2013) 0.81
Association analyses of the INSIG2 polymorphism in the obesity and cholesterol levels of Korean populations. BMC Med Genet (2009) 0.80
Cellular uptake of ginsenosides in Korean white ginseng and red ginseng and their apoptotic activities in human breast cancer cells. Planta Med (2010) 0.80
Metabolic significance of bisphenol A-induced oxidative stress in rat urine measured by liquid chromatography-mass spectrometry. J Appl Toxicol (2009) 0.80
A novel GC-MS method in urinary estrogen analysis from postmenopausal women with osteoporosis. J Lipid Res (2011) 0.80
Metabolic alteration of urinary steroids in pre- and post-menopausal women, and men with papillary thyroid carcinoma. BMC Cancer (2011) 0.80
Mathematical modeling of humoral immune response suppression by passively administered antibodies in mice. J Theor Biol (2006) 0.80
Increased urinary F(2)-isoprostanes levels in the patients with Alzheimer's disease. Brain Res Bull (2004) 0.80
High-temperature GC-MS-based serum cholesterol signatures may reveal sex differences in vasospastic angina. J Lipid Res (2013) 0.79