Bradley R Fruen

Author PubWeight™ 11.95‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Kinetics of FKBP12.6 binding to ryanodine receptors in permeabilized cardiac myocytes and effects on Ca sparks. Circ Res 2010 2.29
2 FRET-based mapping of calmodulin bound to the RyR1 Ca2+ release channel. Proc Natl Acad Sci U S A 2009 1.29
3 Mapping the ryanodine receptor FK506-binding protein subunit using fluorescence resonance energy transfer. J Biol Chem 2010 1.05
4 Localization of the dantrolene-binding sequence near the FK506-binding protein-binding site in the three-dimensional structure of the ryanodine receptor. J Biol Chem 2011 1.05
5 FRET detection of calmodulin binding to the cardiac RyR2 calcium release channel. Biophys J 2011 1.00
6 Cardiac myocyte Z-line calmodulin is mainly RyR2-bound, and reduction is arrhythmogenic and occurs in heart failure. Circ Res 2013 0.98
7 Ablation of skeletal muscle triadin impairs FKBP12/RyR1 channel interactions essential for maintaining resting cytoplasmic Ca2+. J Biol Chem 2010 0.93
8 Calmodulin oxidation and methionine to glutamine substitutions reveal methionine residues critical for functional interaction with ryanodine receptor-1. J Biol Chem 2003 0.90
9 Role of calmodulin methionine residues in mediating productive association with cardiac ryanodine receptors. Am J Physiol Heart Circ Physiol 2005 0.89
10 In cardiomyocytes, binding of unzipping peptide activates ryanodine receptor 2 and reciprocally inhibits calmodulin binding. Circ Res 2012 0.84
11 Calmodulin dissociation mediates desensitization of the cADPR-induced Ca2+ release mechanism. Curr Biol 2002 0.79