Peripheral T cell lymphoma: new model + new insight.

Characterization of a new mouse model for peripheral T cell lymphoma in humans. PLoS One (2011) 0.76

Overview of the Use of Murine Models in Leukemia and Lymphoma Research. Front Oncol (2017) 0.75

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma. Nature (2010) 8.78

Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia. Blood (2009) 5.84

Mechanisms of B-cell lymphoma pathogenesis. Nat Rev Cancer (2005) 4.66

Tyrosine kinase SYK: essential functions for immunoreceptor signalling. Immunol Today (2000) 2.43

Proteomic and genetic approaches identify Syk as an AML target. Cancer Cell (2009) 2.39

Novel t(5;9)(q33;q22) fuses ITK to SYK in unspecified peripheral T-cell lymphoma. Leukemia (2006) 2.24

Gene expression analysis of peripheral T cell lymphoma, unspecified, reveals distinct profiles and new potential therapeutic targets. J Clin Invest (2007) 1.97

The Syk family of protein tyrosine kinases in T-cell activation and development. Immunol Rev (1998) 1.81

Overexpression of Syk tyrosine kinase in peripheral T-cell lymphomas. Leukemia (2008) 1.75

The Tec kinases Itk and Rlk regulate conventional versus innate T-cell development. Immunol Rev (2009) 1.25

Distinct roles for Syk and ZAP-70 during early thymocyte development. J Exp Med (2007) 1.24

Molecular mechanism of the Syk activation switch. J Biol Chem (2008) 1.22

The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma. J Exp Med (2010) 1.18

Molecular classification of T-cell lymphomas. Crit Rev Oncol Hematol (2009) 1.09

Exploiting cellular pathways to develop new treatment strategies for AML. Cancer Treat Rev (2010) 1.03

Current and future aggressive peripheral T-cell lymphoma treatment paradigms, biological features and therapeutic molecular targets. Crit Rev Oncol Hematol (2008) 0.99

Conformational snapshots of Tec kinases during signaling. Immunol Rev (2009) 0.93

Pathobiology of mature T-cell lymphomas. Clin Lymphoma Myeloma (2008) 0.84

Gatekeeper pathways and cellular background in the pathogenesis and therapy of AML. Leukemia (2005) 0.82

Transgenic mice as an in vivo model of lymphomagenesis. Int Rev Cytol (2004) 0.79