Published in Annu Rev Cell Dev Biol on January 01, 2007
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Distinct role of rab27a in granule movement at the plasma membrane and in the cytosol of NK cells. PLoS One (2010) 0.99
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The role of the cytoskeleton at the immunological synapse. Immunol Rev (2013) 0.95
VAMP8-dependent fusion of recycling endosomes with the plasma membrane facilitates T lymphocyte cytotoxicity. J Cell Biol (2015) 0.94
Toxoplasma gondii myosin F, an essential motor for centrosomes positioning and apicoplast inheritance. EMBO J (2013) 0.92
Arf-like GTPase Arl8b regulates lytic granule polarization and natural killer cell-mediated cytotoxicity. Mol Biol Cell (2013) 0.92
Microtubule-organizing center polarity and the immunological synapse: protein kinase C and beyond. Front Immunol (2012) 0.92
Intraflagellar transport: a new player at the immune synapse. Trends Immunol (2011) 0.91
Hemophagocytic lymphohistiocytosis caused by dominant-negative mutations in STXBP2 that inhibit SNARE-mediated membrane fusion. Blood (2015) 0.91
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Neuroprotective intervention by interferon-γ blockade prevents CD8+ T cell-mediated dendrite and synapse loss. J Exp Med (2013) 0.85
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The adaptor protein Crk in immune response. Immunol Cell Biol (2013) 0.81
WF10 stimulates NK cell cytotoxicity by increasing LFA-1-mediated adhesion to tumor cells. J Biomed Biotechnol (2011) 0.81
Cytotoxic T lymphocyte perforin and Fas ligand working in concert even when Fas ligand lytic action is still not detectable. Immunology (2011) 0.81
Mother Centriole Distal Appendages Mediate Centrosome Docking at the Immunological Synapse and Reveal Mechanistic Parallels with Ciliogenesis. Curr Biol (2015) 0.80
Molecular mechanisms and functional implications of polarized actin remodeling at the T cell immunological synapse. Cell Mol Life Sci (2014) 0.79
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Natural killer lytic-associated molecule plays a role in controlling tumor dissemination and metastasis. Front Immunol (2012) 0.78
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Lipid-based patterning of the immunological synapse. Biochem Soc Trans (2014) 0.76
ASMase: the tailor of cytotoxic T cell granule exocytosis. Nat Immunol (2009) 0.75
"Cell biology meets physiology: functional organization of vertebrate plasma membranes"--the immunological synapse. Curr Top Membr (2013) 0.75
EBAG9 tempers lymphocyte killing activity. J Clin Invest (2009) 0.75
Spread of HTLV-I between lymphocytes by virus-induced polarization of the cytoskeleton. Science (2003) 5.19
Centrosome polarization delivers secretory granules to the immunological synapse. Nature (2006) 4.28
Secretory lysosomes. Nat Rev Mol Cell Biol (2002) 3.70
Adaptor protein 3-dependent microtubule-mediated movement of lytic granules to the immunological synapse. Nat Immunol (2003) 2.56
The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation. J Exp Med (2007) 2.37
The strength of T cell receptor signal controls the polarization of cytotoxic machinery to the immunological synapse. Immunity (2009) 2.16
Linking albinism and immunity: the secrets of secretory lysosomes. Science (2004) 2.07
Hedgehog signaling controls T cell killing at the immunological synapse. Science (2013) 1.84
A general role for Rab27a in secretory cells. Mol Biol Cell (2003) 1.76
Delivering the kiss of death. Nat Immunol (2003) 1.72
The leaden gene product is required with Rab27a to recruit myosin Va to melanosomes in melanocytes. Traffic (2002) 1.59
Syntaxin 11 is required for NK and CD8⁺ T-cell cytotoxicity and neutrophil degranulation. Eur J Immunol (2012) 1.57
Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse. Traffic (2008) 1.38
CTL secretory lysosomes: biogenesis and secretion of a harmful organelle. Semin Immunol (2005) 1.35
Sorting of Fas ligand to secretory lysosomes is regulated by mono-ubiquitylation and phosphorylation. J Cell Sci (2006) 1.32
Regulating secretory lysosomes. J Biochem (2006) 1.26
Molecular basis of familial hemophagocytic lymphohistiocytosis. Haematologica (2010) 1.25
Positive and negative signaling through SLAM receptors regulate synapse organization and thresholds of cytolysis. Immunity (2012) 1.20
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A single amino acid change, A91V, leads to conformational changes that can impair processing to the active form of perforin. Blood (2005) 1.12
STXBP2 mutations in children with familial haemophagocytic lymphohistiocytosis type 5. J Med Genet (2010) 1.11
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The secretory synapse: the secrets of a serial killer. Immunol Rev (2002) 1.08
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Genotype-phenotype study of familial haemophagocytic lymphohistiocytosis type 3. J Med Genet (2011) 1.05
Two patients with Hermansky Pudlak syndrome type 2 and novel mutations in AP3B1. Haematologica (2009) 1.03
Microtubule-dependent transport of secretory vesicles in RBL-2H3 cells. Traffic (2003) 1.03
Syntaxin binding mechanism and disease-causing mutations in Munc18-2. Proc Natl Acad Sci U S A (2013) 1.01
The role of the secretory immunological synapse in killing by CD8+ CTL. Semin Immunol (2003) 1.00
A role for Rab7 in the movement of secretory granules in cytotoxic T lymphocytes. Traffic (2011) 0.98
The role of the cytoskeleton at the immunological synapse. Immunol Rev (2013) 0.95
Mutations affecting mRNA splicing are the most common molecular defect in patients with familial hemophagocytic lymphohistiocytosis type 3. Haematologica (2008) 0.89
Normal lytic granule secretion by cytotoxic T lymphocytes deficient in BLOC-1, -2 and -3 and myosins Va, VIIa and XV. Traffic (2005) 0.85
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Reduced type I interferon production by dendritic cells and weakened antiviral immunity in patients with Wiskott-Aldrich syndrome protein deficiency. J Allergy Clin Immunol (2012) 0.82
Secretion from Myeloid Cells: Secretory Lysosomes. Microbiol Spectr (2016) 0.75