Signaling from axon guidance receptors.

Mechanisms and molecules of neuronal wiring: a primer. Cold Spring Harb Perspect Biol (2011) 2.62

The growth cone cytoskeleton in axon outgrowth and guidance. Cold Spring Harb Perspect Biol (2011) 2.22

The central dogma decentralized: new perspectives on RNA function and local translation in neurons. Neuron (2013) 2.21

Rho and Ras GTPases in axon growth, guidance, and branching. Cold Spring Harb Perspect Biol (2010) 2.17

Extracellular inhibitors, repellents, and semaphorin/plexin/MICAL-mediated actin filament disassembly. Cytoskeleton (Hoboken) (2011) 1.12

The RacGAP β2-Chimaerin selectively mediates axonal pruning in the hippocampus. Cell (2012) 1.08

Ephrin reverse signaling in axon guidance and synaptogenesis. Semin Cell Dev Biol (2011) 1.07

Diffusion tensor imaging and fiber tractography in brain malformations. Pediatr Radiol (2013) 1.07

Potential contribution of exosomes to the prion-like propagation of lesions in Alzheimer's disease. Front Physiol (2012) 1.05

Genetic dissection of axon regeneration. Curr Opin Neurobiol (2010) 1.03

Molecular mechanisms of tumor angiogenesis. Genes Cancer (2011) 0.96

Local caspase activation interacts with Slit-Robo signaling to restrict axonal arborization. J Cell Biol (2013) 0.96

PlexinA1 is a new Slit receptor and mediates axon guidance function of Slit C-terminal fragments. Nat Neurosci (2014) 0.95

Eph/ephrin interactions modulate muscle satellite cell motility and patterning. Development (2011) 0.95

Netrin-1 attracts axons through FAK-dependent mechanotransduction. J Neurosci (2012) 0.94

The Control of semaphorin-1a-mediated reverse signaling by opposing pebble and RhoGAPp190 functions in drosophila. Neuron (2012) 0.93

A parallel genome-wide mRNA and microRNA profiling of the frontal cortex of HIV patients with and without HIV-associated dementia shows the role of axon guidance and downstream pathways in HIV-mediated neurodegeneration. BMC Genomics (2012) 0.93

FLRT structure: balancing repulsion and cell adhesion in cortical and vascular development. Neuron (2014) 0.92

Sculpting Neural Circuits by Axon and Dendrite Pruning. Annu Rev Cell Dev Biol (2015) 0.91

14-3-3ε couples protein kinase A to semaphorin signaling and silences plexin RasGAP-mediated axonal repulsion. Neuron (2012) 0.90

Hypoxia disruption of vertebrate CNS pathfinding through ephrinB2 Is rescued by magnesium. PLoS Genet (2012) 0.89

Antagonistic functions of Dishevelleds regulate Frizzled3 endocytosis via filopodia tips in Wnt-mediated growth cone guidance. J Neurosci (2013) 0.88

Dopaminergic axon guidance: which makes what? Front Cell Neurosci (2012) 0.88

UNC-40/DCC, SAX-3/Robo, and VAB-1/Eph polarize F-actin during embryonic morphogenesis by regulating the WAVE/SCAR actin nucleation complex. PLoS Genet (2012) 0.88

The extracellular matrix proteoglycan perlecan facilitates transmembrane semaphorin-mediated repulsive guidance. Genes Dev (2012) 0.87

Peripheral somatosensation: a touch of genetics. Curr Opin Genet Dev (2011) 0.87

Less than 5 Netrin-1 molecules initiate attraction but 200 Sema3A molecules are necessary for repulsion. Sci Rep (2012) 0.86

Dendrite self-avoidance requires cell-autonomous slit/robo signaling in cerebellar purkinje cells. Neuron (2014) 0.86

Schwann cells reposition a peripheral nerve to isolate it from postembryonic remodeling of its targets. Development (2010) 0.86

Microtopographical features generated by photopolymerization recruit RhoA/ROCK through TRPV1 to direct cell and neurite growth. Biomaterials (2015) 0.85

Binge cocaine administration in adolescent rats affects amygdalar gene expression patterns and alters anxiety-related behavior in adulthood. Biol Psychiatry (2011) 0.84

Xenopus sonic hedgehog guides retinal axons along the optic tract. Dev Dyn (2010) 0.83

MIG-10 functions with ABI-1 to mediate the UNC-6 and SLT-1 axon guidance signaling pathways. PLoS Genet (2012) 0.81

Analysis of the VAV3 as candidate gene for schizophrenia: evidences from voxel-based morphometry and mutation screening. Schizophr Bull (2012) 0.81

Activation of glial FGFRs is essential in glial migration, proliferation, and survival and in glia-neuron signaling during olfactory system development. PLoS One (2012) 0.81

Src and cortactin promote lamellipodia protrusion and filopodia formation and stability in growth cones. Mol Biol Cell (2015) 0.80

Cellular and molecular introduction to brain development. Neurobiol Dis (2015) 0.80

The SSRI citalopram affects fetal thalamic axon responsiveness to netrin-1 in vitro independently of SERT antagonism. Neuropsychopharmacology (2012) 0.80

The cell biology of synaptic specificity during development. Curr Opin Neurobiol (2013) 0.80

Reverse Signaling by Semaphorin-6A Regulates Cellular Aggregation and Neuronal Morphology. PLoS One (2016) 0.79

Sugar-dependent modulation of neuronal development, regeneration, and plasticity by chondroitin sulfate proteoglycans. Exp Neurol (2015) 0.79

Live cell imaging of neuronal growth cone motility and guidance in vitro. Methods Mol Biol (2011) 0.79

Function of the Drosophila receptor guanylyl cyclase Gyc76C in PlexA-mediated motor axon guidance. Development (2013) 0.79

Regulating small G protein signaling to coordinate axon adhesion and repulsion. Small GTPases (2012) 0.79

Phenotype-dependent alteration of pathways and networks reveals a pure synergistic mechanism for compounds treating mouse cerebral ischemia. Acta Pharmacol Sin (2015) 0.78

MSC secretes at least 3 EV types each with a unique permutation of membrane lipid, protein and RNA. J Extracell Vesicles (2016) 0.78

Evidence for a role of srGAP3 in the positioning of commissural axons within the ventrolateral funiculus of the mouse spinal cord. PLoS One (2011) 0.78

Glutamate Stimulates Local Protein Synthesis in the Axons of Rat Cortical Neurons by Activating α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors and Metabotropic Glutamate Receptors. J Biol Chem (2015) 0.77

Adult Drosophila sensory neurons specify dendritic territories independently of dendritic contacts through the Wnt5-Drl signaling pathway. Genes Dev (2015) 0.76

p120RasGAP Protein Mediates Netrin-1 Protein-induced Cortical Axon Outgrowth and Guidance. J Biol Chem (2015) 0.76

F-actin dismantling through a redox-driven synergy between Mical and cofilin. Nat Cell Biol (2016) 0.76

Integrative analysis of neuroblastoma and pheochromocytoma genomics data. BMC Med Genomics (2012) 0.76

Repulsive axon guidance cues ephrin-A2 and slit3 stop protrusion of the growth cone leading margin concurrently with inhibition of ADF/cofilin and ERM proteins. Cytoskeleton (Hoboken) (2012) 0.76

The discovery of the growth cone and its influence on the study of axon guidance. Front Neuroanat (2015) 0.76

Dual leucine zipper kinase regulates expression of axon guidance genes in mouse neuronal cells. Neural Dev (2016) 0.75

Equivalent Activities of Repulsive Axon Guidance Receptors. J Neurosci (2016) 0.75

Eph and Ephrin function in dispersal and epithelial insertion of pigmented immunocytes in sea urchin embryos. Elife (2016) 0.75

Δ9-Tetrahydrocannabinol (Δ9-THC) Promotes Neuroimmune-Modulatory MicroRNA Profile in Striatum of Simian Immunodeficiency Virus (SIV)-Infected Macaques. J Neuroimmune Pharmacol (2015) 0.75

Role of Netrin-1 Signaling in Nerve Regeneration. Int J Mol Sci (2017) 0.75

Hsc70 chaperone activity underlies Trio GEF function in axon growth and guidance induced by netrin-1. J Cell Biol (2015) 0.75

A GAL4-inducible transgenic tool kit for the in vivo modulation of Rho GTPase activity in zebrafish. Dev Dyn (2016) 0.75

Structural Basis for Plexin Activation and Regulation. Neuron (2016) 0.75

Polo-Like Kinase 3 Appears Dispensable for Normal Retinal Development Despite Robust Embryonic Expression. PLoS One (2016) 0.75

Proteome dynamics during postnatal mouse corpus callosum development. Sci Rep (2017) 0.75

Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice. Nat Neurosci (2017) 0.75

Estrogen Receptor Alpha (ESR1)-Dependent Regulation of the Mouse Oviductal Transcriptome. PLoS One (2016) 0.75

Can hippocampal neurites and growth cones climb over obstacles? PLoS One (2013) 0.75

A Serotonin Circuit Acts as an Environmental Sensor to Mediate Midline Axon Crossing through EphrinB2. J Neurosci (2015) 0.75

Sevoflurane Impairs Growth Cone Motility in Dissociated Murine Neurons. J Neurosurg Anesthesiol (2016) 0.75

SYD-1C, UNC-40 (DCC) and SAX-3 (Robo) function interdependently to promote axon guidance by regulating the MIG-2 GTPase. PLoS Genet (2015) 0.75

A1 Adenosine Receptor Activation Modulates Central Nervous System Development and Repair. Mol Neurobiol (2016) 0.75

Varicose and cheerio collaborate with pebble to mediate semaphorin-1a reverse signaling in Drosophila. Proc Natl Acad Sci U S A (2017) 0.75

Notch signaling: from the outside in. Dev Biol (2000) 6.06

Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis. Cell (1997) 3.48

Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway. Cell (2001) 3.44

Conversion of neuronal growth cone responses from repulsion to attraction by cyclic nucleotides. Science (1998) 3.42

Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans. Cell (2005) 3.34

EphB-ephrinB bi-directional endocytosis terminates adhesion allowing contact mediated repulsion. Nat Cell Biol (2003) 3.26

Regulated cleavage of a contact-mediated axon repellent. Science (2000) 3.24

Nuk controls pathfinding of commissural axons in the mammalian central nervous system. Cell (1996) 3.19

cAMP-induced switching in turning direction of nerve growth cones. Nature (1997) 2.90

Rac function and regulation during Drosophila development. Nature (2002) 2.89

FARP2 triggers signals for Sema3A-mediated axonal repulsion. Nat Neurosci (2005) 2.87

Essential role of TRPC channels in the guidance of nerve growth cones by brain-derived neurotrophic factor. Nature (2005) 2.78

KUZ, a conserved metalloprotease-disintegrin protein with two roles in Drosophila neurogenesis. Science (1996) 2.77

Analysis of the L1-deficient mouse phenotype reveals cross-talk between Sema3A and L1 signaling pathways in axonal guidance. Neuron (2000) 2.73

Vav family GEFs link activated Ephs to endocytosis and axon guidance. Neuron (2005) 2.72

Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology. Neuron (2002) 2.59

Eph-dependent tyrosine phosphorylation of ephexin1 modulates growth cone collapse. Neuron (2005) 2.52

Requirement of TRPC channels in netrin-1-induced chemotropic turning of nerve growth cones. Nature (2005) 2.42

Netrin requires focal adhesion kinase and Src family kinases for axon outgrowth and attraction. Nat Neurosci (2004) 2.41

Slit stimulation recruits Dock and Pak to the roundabout receptor and increases Rac activity to regulate axon repulsion at the CNS midline. Neuron (2003) 2.39

Growth-cone attraction to netrin-1 is converted to repulsion by laminin-1. Nature (1999) 2.37

The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals. Nature (2001) 2.34

EphrinB phosphorylation and reverse signaling: regulation by Src kinases and PTP-BL phosphatase. Mol Cell (2002) 2.31

Cyclic AMP/GMP-dependent modulation of Ca2+ channels sets the polarity of nerve growth-cone turning. Nature (2003) 2.18

Rho and Ras GTPases in axon growth, guidance, and branching. Cold Spring Harb Perspect Biol (2010) 2.17

A TrkB/EphrinA interaction controls retinal axon branching and synaptogenesis. J Neurosci (2008) 2.15

Binding of DCC by netrin-1 to mediate axon guidance independent of adenosine A2B receptor activation. Science (2001) 2.14

Age-related changes underlie switch in netrin-1 responsiveness as growth cones advance along visual pathway. Nat Neurosci (2002) 2.06

Plexin B mediates axon guidance in Drosophila by simultaneously inhibiting active Rac and enhancing RhoA signaling. Neuron (2001) 2.05

Nervy links protein kinase a to plexin-mediated semaphorin repulsion. Science (2004) 2.00

Focal adhesion kinase in netrin-1 signaling. Nat Neurosci (2004) 1.99

Sonic hedgehog guides axons through a noncanonical, Src-family-kinase-dependent signaling pathway. Neuron (2009) 1.99

Guiding neuronal growth cones using Ca2+ signals. Trends Cell Biol (2004) 1.97

p75(NTR) mediates ephrin-A reverse signaling required for axon repulsion and mapping. Neuron (2008) 1.97

Calcium signalling in the guidance of nerve growth by netrin-1. Nature (2000) 1.96

The netrin receptor UNC-40/DCC stimulates axon attraction and outgrowth through enabled and, in parallel, Rac and UNC-115/AbLIM. Neuron (2003) 1.95

Ephrin-A5 induces collapse of growth cones by activating Rho and Rho kinase. J Cell Biol (2000) 1.94

Trio combines with dock to regulate Pak activity during photoreceptor axon pathfinding in Drosophila. Cell (2000) 1.90

Dosage-sensitive, reciprocal genetic interactions between the Abl tyrosine kinase and the putative GEF trio reveal trio's role in axon pathfinding. Neuron (2000) 1.90

Calcium signaling in neuronal motility. Annu Rev Cell Dev Biol (2007) 1.89

Activation of FAK and Src are receptor-proximal events required for netrin signaling. Nat Neurosci (2004) 1.89

The molecular basis for calcium-dependent axon pathfinding. Nat Rev Neurosci (2006) 1.87

Rac-GAP alpha-chimerin regulates motor-circuit formation as a key mediator of EphrinB3/EphA4 forward signaling. Cell (2007) 1.82

Rac1 mediates collapsin-1-induced growth cone collapse. J Neurosci (1997) 1.79

A presynaptic homeostatic signaling system composed of the Eph receptor, ephexin, Cdc42, and CaV2.1 calcium channels. Neuron (2009) 1.79

Fyn and Cdk5 mediate semaphorin-3A signaling, which is involved in regulation of dendrite orientation in cerebral cortex. Neuron (2002) 1.71

Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation. Nat Neurosci (2007) 1.66

Endocytosis-dependent desensitization and protein synthesis-dependent resensitization in retinal growth cone adaptation. Nat Neurosci (2005) 1.63

Function of an axonal chemoattractant modulated by metalloprotease activity. Science (2000) 1.63

Metalloproteinase/Presenilin1 processing of ephrinB regulates EphB-induced Src phosphorylation and signaling. EMBO J (2006) 1.62

A chemokine, SDF-1, reduces the effectiveness of multiple axonal repellents and is required for normal axon pathfinding. J Neurosci (2003) 1.61

Netrin-1-mediated axon outgrowth and cAMP production requires interaction with adenosine A2b receptor. Nature (2000) 1.60

Turning of nerve growth cones induced by localized increases in intracellular calcium ions. Nature (2000) 1.58

Rac1-mediated endocytosis during ephrin-A2- and semaphorin 3A-induced growth cone collapse. J Neurosci (2002) 1.55

The netrin-1 receptor DCC promotes filopodia formation and cell spreading by activating Cdc42 and Rac1. Mol Cell Neurosci (2002) 1.55

XTRPC1-dependent chemotropic guidance of neuronal growth cones. Nat Neurosci (2005) 1.55

Compartmentalized signaling by GPI-anchored ephrin-A5 requires the Fyn tyrosine kinase to regulate cellular adhesion. Genes Dev (1999) 1.52

Ephrin-B3 reverse signaling through Grb4 and cytoskeletal regulators mediates axon pruning. Nat Neurosci (2009) 1.50

alpha2-Chimaerin is an essential EphA4 effector in the assembly of neuronal locomotor circuits. Neuron (2007) 1.49

EphA4-dependent axon guidance is mediated by the RacGAP alpha2-chimaerin. Neuron (2007) 1.48

Rac1 and Cdc42 but not RhoA or Rho kinase activities are required for neurite outgrowth induced by the Netrin-1 receptor DCC (deleted in colorectal cancer) in N1E-115 neuroblastoma cells. J Biol Chem (2002) 1.48

The Abelson tyrosine kinase, the Trio GEF and Enabled interact with the Netrin receptor Frazzled in Drosophila. Development (2005) 1.46

Ligand binding and calcium influx induce distinct ectodomain/gamma-secretase-processing pathways of EphB2 receptor. J Biol Chem (2007) 1.44

The plexin-B1/Rac interaction inhibits PAK activation and enhances Sema4D ligand binding. Genes Dev (2002) 1.44

Regulation of EphA 4 kinase activity is required for a subset of axon guidance decisions suggesting a key role for receptor clustering in Eph function. Neuron (2005) 1.44

Soluble adenylyl cyclase is required for netrin-1 signaling in nerve growth cones. Nat Neurosci (2006) 1.41

Vilse, a conserved Rac/Cdc42 GAP mediating Robo repulsion in tracheal cells and axons. Genes Dev (2004) 1.41

Netrin signal transduction and the guanine nucleotide exchange factor DOCK180 in attractive signaling. Nat Neurosci (2007) 1.37

Deleted in colorectal cancer binding netrin-1 mediates cell substrate adhesion and recruits Cdc42, Rac1, Pak1, and N-WASP into an intracellular signaling complex that promotes growth cone expansion. J Neurosci (2005) 1.36

Nerve growth factor and semaphorin 3A signaling pathways interact in regulating sensory neuronal growth cone motility. J Neurosci (2002) 1.35

Nck adaptor proteins control the organization of neuronal circuits important for walking. Proc Natl Acad Sci U S A (2007) 1.33

FARP1 promotes the dendritic growth of spinal motor neuron subtypes through transmembrane Semaphorin6A and PlexinA4 signaling. Neuron (2009) 1.33

Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance. Mol Cell Biol (2008) 1.32

Alpha2-chimaerin interacts with EphA4 and regulates EphA4-dependent growth cone collapse. Proc Natl Acad Sci U S A (2007) 1.32

VAB-8, UNC-73 and MIG-2 regulate axon polarity and cell migration functions of UNC-40 in C. elegans. Nat Neurosci (2007) 1.30

Son of sevenless directly links the Robo receptor to rac activation to control axon repulsion at the midline. Neuron (2006) 1.30

Src family kinases are involved in EphA receptor-mediated retinal axon guidance. J Neurosci (2004) 1.29

Cross GTPase-activating protein (CrossGAP)/Vilse links the Roundabout receptor to Rac to regulate midline repulsion. Proc Natl Acad Sci U S A (2005) 1.28

C. elegans VAB-8 and UNC-73 regulate the SAX-3 receptor to direct cell and growth-cone migrations. Nat Neurosci (2007) 1.26

Presenilin-dependent "gamma-secretase" processing of deleted in colorectal cancer (DCC). J Biol Chem (2003) 1.25

Protein interacting with C-kinase 1/protein kinase Calpha-mediated endocytosis converts netrin-1-mediated repulsion to attraction. J Neurosci (2006) 1.23

Ephrin-B2-induced cleavage of EphB2 receptor is mediated by matrix metalloproteinases to trigger cell repulsion. J Biol Chem (2008) 1.21

Calcium mediates bidirectional growth cone turning induced by myelin-associated glycoprotein. Neuron (2004) 1.20

Membrane potential shifts caused by diffusible guidance signals direct growth-cone turning. Nat Neurosci (2008) 1.16

Phosphorylation of DCC by Fyn mediates Netrin-1 signaling in growth cone guidance. J Cell Biol (2004) 1.16

The activity of the plexin-A1 receptor is regulated by Rac. J Biol Chem (2004) 1.16

p130CAS is required for netrin signaling and commissural axon guidance. J Neurosci (2007) 1.14

The Drosophila receptor guanylyl cyclase Gyc76C is required for semaphorin-1a-plexin A-mediated axonal repulsion. J Neurosci (2004) 1.12

Presenilin-dependent intramembrane cleavage of ephrin-B1. Mol Neurodegener (2006) 1.11

Presenilin attenuates receptor-mediated signaling and synaptic function. J Neurosci (2005) 1.11

Protein kinase A activation promotes plasma membrane insertion of DCC from an intracellular pool: A novel mechanism regulating commissural axon extension. J Neurosci (2004) 1.10

Rho inhibition recruits DCC to the neuronal plasma membrane and enhances axon chemoattraction to netrin 1. Development (2008) 1.08

Stromal cell-derived factor-1 antagonizes slit/robo signaling in vivo. J Neurosci (2007) 1.08

Cyclic GMP-gated CNG channels function in Sema3A-induced growth cone repulsion. Neuron (2008) 1.04

Soluble adenylyl cyclase is not required for axon guidance to netrin-1. J Neurosci (2008) 0.99

The function of leak and kuzbanian during growth cone and cell migration. Mech Dev (2001) 0.98

The neural adhesion molecule TAG-1 modulates responses of sensory axons to diffusible guidance signals. Development (2008) 0.96

Src family kinases are required for WNT5 signaling through the Derailed/RYK receptor in the Drosophila embryonic central nervous system. Development (2008) 0.96

Netrin-1-independent adenosine A2b receptor activation regulates the response of axons to netrin-1 by controlling cell surface levels of UNC5A receptors. J Neurochem (2007) 0.96

Calmodulin and son of sevenless dependent signaling pathways regulate midline crossing of axons in the Drosophila CNS. Development (2000) 0.94

Mechanisms and functions of Eph and ephrin signalling. Nat Rev Mol Cell Biol (2002) 6.92

PDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculature. Genes Dev (2005) 3.29

EphB-ephrinB bi-directional endocytosis terminates adhesion allowing contact mediated repulsion. Nat Cell Biol (2003) 3.26

Bidirectional Eph-ephrin signaling during axon guidance. Trends Cell Biol (2007) 2.83

Notch activation induces apoptosis in neural progenitor cells through a p53-dependent pathway. Dev Biol (2004) 2.59

Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation. Nat Med (2006) 2.59

Hippocampal plasticity requires postsynaptic ephrinBs. Nat Neurosci (2003) 2.37

Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanism. PLoS Biol (2008) 2.35

EphrinB phosphorylation and reverse signaling: regulation by Src kinases and PTP-BL phosphatase. Mol Cell (2002) 2.31

Control of skeletal patterning by ephrinB1-EphB interactions. Dev Cell (2003) 2.11

Mechanism of TrkB-mediated hippocampal long-term potentiation. Neuron (2002) 2.03

Absence of Ret signaling in mice causes progressive and late degeneration of the nigrostriatal system. PLoS Biol (2007) 1.72

Cooperation between GDNF/Ret and ephrinA/EphA4 signals for motor-axon pathway selection in the limb. Neuron (2006) 1.71

Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport. Nat Neurosci (2009) 1.70

GDNF acts as a chemoattractant to support ephrinA-induced repulsion of limb motor axons. Curr Biol (2010) 1.59

EphA4-dependent axon guidance is mediated by the RacGAP alpha2-chimaerin. Neuron (2007) 1.48

Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality. Mol Cell Biol (2007) 1.48

Echogenicity of the substantia nigra: association with increased iron content and marker for susceptibility to nigrostriatal injury. Arch Neurol (2002) 1.45

Regulation of EphA 4 kinase activity is required for a subset of axon guidance decisions suggesting a key role for receptor clustering in Eph function. Neuron (2005) 1.44

c-Jun in Schwann cells promotes axonal regeneration and motoneuron survival via paracrine signaling. J Cell Biol (2012) 1.38

Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors. Nat Neurosci (2008) 1.34

Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling. Mol Cell Proteomics (2006) 1.32

Distinct requirements for TrkB and TrkC signaling in target innervation by sensory neurons. Genes Dev (2002) 1.20

Progressive postnatal motoneuron loss in mice lacking GDF-15. J Neurosci (2009) 1.20

Mitogen-inducible gene 6 is an endogenous inhibitor of HGF/Met-induced cell migration and neurite growth. J Cell Biol (2005) 1.18

The Rab5 guanylate exchange factor Rin1 regulates endocytosis of the EphA4 receptor in mature excitatory neurons. Proc Natl Acad Sci U S A (2008) 1.15

Immunohistochemical evidence of seizure-induced activation of trkB receptors in the mossy fiber pathway of adult mouse hippocampus. J Neurosci (2002) 1.15

RET signaling does not modulate MPTP toxicity but is required for regeneration of dopaminergic axon terminals. Proc Natl Acad Sci U S A (2007) 1.11

FLRT2 and FLRT3 act as repulsive guidance cues for Unc5-positive neurons. EMBO J (2011) 1.11

Release of full-length EphB2 receptors from hippocampal neurons to cocultured glial cells. J Neurosci (2006) 1.10

Inactivation of VCP/ter94 suppresses retinal pathology caused by misfolded rhodopsin in Drosophila. PLoS Genet (2010) 1.08

Forebrain-specific trkB-receptor knockout mice: behaviorally more hyperactive than "depressive". Biol Psychiatry (2003) 1.08

Pro-survival role for Parkinson's associated gene DJ-1 revealed in trophically impaired dopaminergic neurons. PLoS Biol (2010) 1.07

Tyrosine phosphorylation sites in ephrinB2 are required for hippocampal long-term potentiation but not long-term depression. J Neurosci (2007) 1.02

EphB receptors and ephrin-B3 regulate axon guidance at the ventral midline of the embryonic mouse spinal cord. J Neurosci (2006) 1.01

Repairing the parkinsonian brain with neurotrophic factors. Trends Neurosci (2010) 1.01

Role for ephrinB2 in postnatal lung alveolar development and elastic matrix integrity. Dev Dyn (2008) 1.00

Structurally encoded intraclass differences in EphA clusters drive distinct cell responses. Nat Struct Mol Biol (2013) 1.00

Met signaling is required for recruitment of motor neurons to PEA3-positive motor pools. Neuron (2003) 0.99

Genetic ablation of FLRT3 reveals a novel morphogenetic function for the anterior visceral endoderm in suppressing mesoderm differentiation. Genes Dev (2008) 0.98

The composition of EphB2 clusters determines the strength in the cellular repulsion response. J Cell Biol (2014) 0.97

Axon guidance: receptor complexes and signaling mechanisms. Curr Opin Neurobiol (2002) 0.96

Neocortical and cerebellar developmental abnormalities in conditions of selective elimination of peroxisomes from brain or from liver. J Neurosci Res (2007) 0.94

Pitx3 is a critical mediator of GDNF-induced BDNF expression in nigrostriatal dopaminergic neurons. J Neurosci (2011) 0.94

Genetic analysis of EphA-dependent signaling mechanisms controlling topographic mapping in vivo. Development (2006) 0.94

Expression of foetal type acetylcholine receptor is restricted to type 1 muscle fibres in human neuromuscular disorders. Brain (2002) 0.93

Neuron-astrocyte communication and synaptic plasticity. Curr Opin Neurobiol (2010) 0.92

Absence of functional peroxisomes from mouse CNS causes dysmyelination and axon degeneration. J Neurosci (2008) 0.92

Integration of guidance cues: parallel signaling and crosstalk. Trends Neurosci (2013) 0.92

Congenital cystic eye. Graefes Arch Clin Exp Ophthalmol (2003) 0.91

Anatomical coupling of sensory and motor nerve trajectory via axon tracking. Neuron (2011) 0.90

Genetic evidence for a contribution of EphA:ephrinA reverse signaling to motor axon guidance. J Neurosci (2012) 0.90

Spontaneous regression of experimental gliomas--an immunohistochemical and MRI study of the C6 glioma spheroid implantation model. Exp Neurol (2004) 0.90

TEF-1 and C/EBPbeta are major p38alpha MAPK-regulated transcription factors in proliferating cardiomyocytes. Biochem J (2006) 0.89

Protein tyrosine phosphatase receptor type O inhibits trigeminal axon growth and branching by repressing TrkB and Ret signaling. J Neurosci (2013) 0.89

Ephrin-B1 controls the columnar distribution of cortical pyramidal neurons by restricting their tangential migration. Neuron (2013) 0.87

Ret rescues mitochondrial morphology and muscle degeneration of Drosophila Pink1 mutants. EMBO J (2014) 0.87

Surgical resection of osteolytic calvarial lesions: clinicopathological features. Clin Neurol Neurosurg (2010) 0.86

The neuregulin receptor, ErbB4, is not required for normal development and adult maintenance of the substantia nigra pars compacta. J Neurochem (2004) 0.85

Cytogenetic and molecular genetic analyses of giant cell glioblastoma multiforme reveal distinct profiles in giant cell and non-giant cell subpopulations. Cancer Genet Cytogenet (2007) 0.85

The axon's balancing act: cis- and trans-interactions between Ephs and ephrins. Neuron (2011) 0.84

EphA4-mediated ipsilateral corticospinal tract misprojections are necessary for bilateral voluntary movements but not bilateral stereotypic locomotion. J Neurosci (2014) 0.82

Altered expression patterns of EphrinB2 and EphB2 in human umbilical vessels and congenital venous malformations. Pediatr Res (2005) 0.82

The protein dendrite arborization and synapse maturation 1 (Dasm-1) is dispensable for dendrite arborization. Mol Cell Biol (2008) 0.80

Long-term monitoring of hippocampus-dependent behavior in naturalistic settings: mutant mice lacking neurotrophin receptor TrkB in the forebrain show spatial learning but impaired behavioral flexibility. Hippocampus (2002) 0.78

Genetic evidence for the adhesion protein IgSF9/Dasm1 to regulate inhibitory synapse development independent of its intracellular domain. J Neurosci (2014) 0.78

Cyclooxygenase-2 supports tumor proliferation in vestibular schwannomas. Neurosurgery (2011) 0.77

Comparative morphological and immunohistochemical study of human meningioma after intracranial transplantation into nude mice. J Neurosci Methods (2011) 0.77

Rüdiger Klein: reading the guideposts for axon guidance. Interview by Caitlin Sedwick. J Cell Biol (2011) 0.75

Novel effector function for an old receptor. Nat Cell Biol (2002) 0.75

Signalling mechanisms. Curr Opin Neurobiol (2007) 0.75

Primary meningeal sarcoma with leiomyoblastic differentiation complicating pregnancy. Clin Neurol Neurosurg (2010) 0.75

May 2004: newborn with intracranial mass. Brain Pathol (2004) 0.75