Published in Clin Exp Allergy on April 28, 2010
International Union of Basic and Clinical Pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors. Pharmacol Rev (2013) 2.11
Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T(H)2 cells. Nat Immunol (2011) 1.66
T cell homing to epithelial barriers in allergic disease. Nat Med (2012) 1.58
Hepatic macrophage migration and differentiation critical for liver fibrosis is mediated by the chemokine receptor C-C motif chemokine receptor 8 in mice. Hepatology (2012) 1.25
Epidermis instructs skin homing receptor expression in human T cells. Blood (2012) 1.10
CCR8 signaling influences Toll-like receptor 4 responses in human macrophages in inflammatory diseases. Clin Vaccine Immunol (2011) 0.82
The human cutaneous chemokine system. Front Immunol (2011) 0.79
Is there a role for CCR8 in the pathogenesis of asthma? Clin Exp Allergy (2010) 0.77
Moderate aerobic exercise alters migration patterns of antigen specific T helper cells within an asthmatic lung. Brain Behav Immun (2013) 0.75
Asthma Biomarkers: Do They Bring Precision Medicine Closer to the Clinic? Allergy Asthma Immunol Res (2017) 0.75
Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma. N Engl J Med (1992) 11.90
The biology of chemokines and their receptors. Annu Rev Immunol (2000) 9.81
Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cells. J Exp Med (2001) 5.56
Immunologic basis of antigen-induced airway hyperresponsiveness. Annu Rev Immunol (1999) 5.51
Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma. Am Rev Respir Dis (1990) 3.70
Chemokines: immunology's high impact factors. Nat Immunol (2001) 3.36
Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia. Am J Respir Cell Mol Biol (1994) 3.32
The role of T lymphocytes in the pathogenesis of asthma. J Allergy Clin Immunol (2003) 3.22
The chemokine receptor CCR8 is preferentially expressed in Th2 but not Th1 cells. J Immunol (1998) 2.32
Expression and cellular provenance of thymic stromal lymphopoietin and chemokines in patients with severe asthma and chronic obstructive pulmonary disease. J Immunol (2008) 2.07
The C-C chemokine receptors CCR4 and CCR8 identify airway T cells of allergen-challenged atopic asthmatics. J Clin Invest (2001) 2.05
Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma. J Allergy Clin Immunol (2004) 1.92
TH2 cytokine expression in bronchoalveolar lavage fluid T lymphocytes and bronchial submucosa is a feature of asthma and eosinophilic bronchitis. J Allergy Clin Immunol (2002) 1.92
Chemokine-receptor expression on T cells in lung compartments of challenged asthmatic patients. Clin Exp Allergy (2005) 1.76
Identification of T lymphocytes, macrophages, and activated eosinophils in the bronchial mucosa in intrinsic asthma. Relationship to symptoms and bronchial responsiveness. Am Rev Respir Dis (1992) 1.68
The immunopathology of extrinsic (atopic) and intrinsic (non-atopic) asthma: more similarities than differences. Immunol Today (1999) 1.67
Expression of chemokine receptors by lung T cells from normal and asthmatic subjects. J Immunol (2001) 1.67
Tregs and allergic disease. J Clin Invest (2004) 1.64
New insights into the relationship between airway inflammation and asthma. Clin Sci (Lond) (2002) 1.47
Cytokine coexpression during human Th1/Th2 cell differentiation: direct evidence for coordinated expression of Th2 cytokines. J Immunol (2002) 1.41
Cutting Edge: Chemokine receptor CCR4 is necessary for antigen-driven cutaneous accumulation of CD4 T cells under physiological conditions. J Immunol (2007) 1.39
Contribution of CCR4 and CCR8 to antigen-specific T(H)2 cell trafficking in allergic pulmonary inflammation. J Allergy Clin Immunol (2008) 1.25
CCR8 expression identifies CD4 memory T cells enriched for FOXP3+ regulatory and Th2 effector lymphocytes. J Immunol (2006) 1.25
Release of both CCR4-active and CXCR3-active chemokines during human allergic pulmonary late-phase reactions. J Allergy Clin Immunol (2003) 1.25
Changes in T-lymphocyte subpopulations after antigenic bronchial provocation in asthmatics. N Engl J Med (1984) 1.23
TGF-beta and IL-13 synergistically increase eotaxin-1 production in human airway fibroblasts. J Immunol (2002) 1.22
Expression of CXCR6 and its ligand CXCL16 in the lung in health and disease. Clin Exp Allergy (2005) 1.22
CCR8 is not essential for the development of inflammation in a mouse model of allergic airway disease. J Immunol (2003) 1.21
Absence of CCR8 does not impair the response to ovalbumin-induced allergic airway disease. J Immunol (2003) 1.19
Identification of the CC chemokines TARC and macrophage inflammatory protein-1 beta as novel functional ligands for the CCR8 receptor. Eur J Immunol (1998) 1.18
Gene expression of the GATA-3 transcription factor is increased in atopic asthma. J Allergy Clin Immunol (1999) 1.16
IL-4-expressing bronchoalveolar T cells from asthmatic and healthy subjects preferentially express CCR 3 and CCR 4. J Allergy Clin Immunol (2005) 1.13
Th-2 cytokines in allergic disease. Br Med Bull (2000) 1.10
Coordinated involvement of mast cells and T cells in allergic mucosal inflammation: critical role of the CC chemokine ligand 1:CCR8 axis. J Immunol (2007) 1.10
T-cell responses in allergy and asthma. Curr Opin Allergy Clin Immunol (2001) 1.02
Chemokines and their receptors in asthma and chronic obstructive pulmonary disease. Curr Opin Pulm Med (2003) 0.94
CC chemokine ligand 1 is released into the airways of atopic asthmatics. Eur Respir J (2006) 0.93
Design, synthesis, and progress toward optimization of potent small molecule antagonists of CC chemokine receptor 8 (CCR8). J Med Chem (2006) 0.87
Remission of chronic fungal asthma in the absence of CCR8. J Allergy Clin Immunol (2007) 0.86
The assignment of chemokine-chemokine receptor pairs: TARC and MIP-1 beta are not ligands for human CC-chemokine receptor 8. Eur J Immunol (1999) 0.85
Recruitment of circulating allergen-specific T lymphocytes to the lung on allergen challenge in asthma. J Allergy Clin Immunol (1997) 0.83
Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma. J Clin Invest (1991) 3.88
The use of induced sputum to investigate airway inflammation. Thorax (1997) 3.85
Eosinophilic bronchitis is an important cause of chronic cough. Am J Respir Crit Care Med (1999) 3.84
Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma. Am Rev Respir Dis (1990) 3.70
Sputum eosinophilia and short-term response to prednisolone in chronic obstructive pulmonary disease: a randomised controlled trial. Lancet (2000) 3.63
Non-eosinophilic corticosteroid unresponsive asthma. Lancet (1999) 3.25
A new perspective on concepts of asthma severity and control. Eur Respir J (2008) 3.16
Bronchial biopsies in asthma. An ultrastructural, quantitative study and correlation with hyperreactivity. Am Rev Respir Dis (1989) 3.06
Development of a symptom specific health status measure for patients with chronic cough: Leicester Cough Questionnaire (LCQ). Thorax (2003) 2.93
Platelet-activating factor. A potent chemotactic and chemokinetic factor for human eosinophils. J Clin Invest (1986) 2.90
Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation? J Exp Med (1999) 2.84
Eosinophilic airway inflammation and exacerbations of COPD: a randomised controlled trial. Eur Respir J (2007) 2.78
Interaction and dose equivalence of salbutamol and salmeterol in patients with asthma. BMJ (1993) 2.70
Analysis of induced sputum in adults with asthma: identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids. Thorax (2002) 2.63
Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion. Nature (1994) 2.57
Unique subpopulations of CD56+ NK and NK-T peripheral blood lymphocytes identified by chemokine receptor expression repertoire. J Immunol (2001) 2.53
Bronchodilator, cardiovascular, and hypokalaemic effects of fenoterol, salbutamol, and terbutaline in asthma. Lancet (1990) 2.52
CCR7 expression and memory T cell diversity in humans. J Immunol (2001) 2.42
Dietary antioxidant vitamin intake and lung function in the general population. Am J Respir Crit Care Med (1995) 2.25
Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs. J Allergy Clin Immunol (2012) 2.17
Respiratory medicine: fighting for survival. BMJ (1992) 2.15
A novel chemokine ligand for CCR10 and CCR3 expressed by epithelial cells in mucosal tissues. J Immunol (2000) 2.13
Expression cloning of the STRL33/BONZO/TYMSTRligand reveals elements of CC, CXC, and CX3C chemokines. J Immunol (2001) 2.12
The Leicester Cough Monitor: preliminary validation of an automated cough detection system in chronic cough. Eur Respir J (2008) 2.01
Developmental switches in chemokine response profiles during B cell differentiation and maturation. J Exp Med (2000) 1.96
Sputum IL-5 concentration is associated with a sputum eosinophilia and attenuated by corticosteroid therapy in COPD. Respiration (2009) 1.92
IL-5 enhances the in vitro adhesion of human eosinophils, but not neutrophils, in a leucocyte integrin (CD11/18)-dependent manner. Immunology (1990) 1.85
Lack of chemokine receptor CCR1 enhances Th1 responses and glomerular injury during nephrotoxic nephritis. J Clin Invest (1999) 1.84
Airway inflammation, airway responsiveness and cough before and after inhaled budesonide in patients with eosinophilic bronchitis. Eur Respir J (2000) 1.81
Sputum eosinophilia and the short term response to inhaled mometasone in chronic obstructive pulmonary disease. Thorax (2005) 1.81
Profiling of sputum inflammatory mediators in asthma and chronic obstructive pulmonary disease. Respiration (2011) 1.78
Multi-dimensional phenotyping: towards a new taxonomy for airway disease. Clin Exp Allergy (2005) 1.77
Comparison of airway immunopathology of eosinophilic bronchitis and asthma. Thorax (2003) 1.75
Relative contribution of endogenous neurotrophins in hippocampal long-term potentiation. J Neurosci (1999) 1.74
Activation of human lung mast cells by monomeric immunoglobulin E. Eur Respir J (2005) 1.74
Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature (1993) 1.71
Human eosinophil, but not neutrophil, adherence to IL-1-stimulated human umbilical vascular endothelial cells is alpha 4 beta 1 (very late antigen-4) dependent. J Immunol (1991) 1.67
Expression of chemokine receptors by lung T cells from normal and asthmatic subjects. J Immunol (2001) 1.67
Expression of mRNA and immunoreactivity for the granulocyte/macrophage colony-stimulating factor in activated human eosinophils. J Exp Med (1991) 1.64
New insights into the role of the mast cell in asthma. Clin Exp Allergy (2003) 1.61
Interleukin-5 selectively enhances the chemotactic response of eosinophils obtained from normal but not eosinophilic subjects. Blood (1992) 1.59
Neurotrophin release by neurotrophins: implications for activity-dependent neuronal plasticity. Proc Natl Acad Sci U S A (1997) 1.55
The use of exhaled nitric oxide concentration to identify eosinophilic airway inflammation: an observational study in adults with asthma. Clin Exp Allergy (2005) 1.52
Respiratory symptoms in patients with treated hypothyroidism and inflammatory bowel disease. Thorax (2003) 1.51
New insights into the relationship between airway inflammation and asthma. Clin Sci (Lond) (2002) 1.47
Leukotriene antagonists and symptom control in chronic persistent asthma. Lancet (2001) 1.46
Variability of bronchial inflammation in chronic obstructive pulmonary disease: implications for study design. Eur Respir J (2006) 1.45
Discrete steps in binding and signaling of interleukin-8 with its receptor. J Biol Chem (1996) 1.42
Telomere dysfunction and chromosome structure modulate the contribution of individual chromosomes in abnormal nuclear morphologies. Mutat Res (2010) 1.41
Videomicroscopy of venular malformations (port-wine stain type): prediction of response to pulsed dye laser. Pediatr Dermatol (2004) 1.40
Functional KCa3.1 K+ channels are required for human lung mast cell migration. Thorax (2006) 1.39
Interleukin-4 and -13 expression is co-localized to mast cells within the airway smooth muscle in asthma. Clin Exp Allergy (2003) 1.37
Induced sputum and other outcome measures in chronic obstructive pulmonary disease: safety and repeatability. Respir Med (2001) 1.31
Airway mucosal inflammation in COPD is similar in smokers and ex-smokers: a pooled analysis. Eur Respir J (2007) 1.30
Molecular and clinical rationale for therapeutic targeting of interleukin-5 and its receptor. Clin Exp Allergy (2011) 1.30
Genome-wide association study to identify genetic determinants of severe asthma. Thorax (2012) 1.27
Adhesion to fibronectin prolongs eosinophil survival. J Exp Med (1993) 1.25
Adhesion of human lung mast cells to bronchial epithelium: evidence for a novel carbohydrate-mediated mechanism. J Leukoc Biol (2000) 1.24
Induced sputum eicosanoid concentrations in asthma. Am J Respir Crit Care Med (1999) 1.24
Transfection of cells from patients with leukocyte adhesion deficiency with an integrin beta subunit (CD18) restores lymphocyte function-associated antigen-1 expression and function. J Clin Invest (1990) 1.24
Expression of CXCR6 and its ligand CXCL16 in the lung in health and disease. Clin Exp Allergy (2005) 1.22
Amino-terminally modified RANTES analogues demonstrate differential effects on RANTES receptors. J Biol Chem (1999) 1.22
Beneficial effects of targeting CCR5 in allograft recipients. Transplantation (2001) 1.22
Production of the novel C-C chemokine MCP-4 by airway cells and comparison of its biological activity to other C-C chemokines. J Clin Invest (1997) 1.22
Idiopathic chronic cough: association with organ specific autoimmune disease and bronchoalveolar lymphocytosis. Thorax (2003) 1.19
Structure and function of the murine chemokine receptor CXCR3. Eur J Immunol (1999) 1.18
Eosinophil adhesion to nasal polyp endothelium is P-selectin-dependent. J Exp Med (1994) 1.17
Induced sputum inflammatory mediator concentrations in eosinophilic bronchitis and asthma. Am J Respir Crit Care Med (2000) 1.15
Expression of endothelial and leukocyte adhesion molecules interacellular adhesion molecule-1, E-selectin, and vascular cell adhesion molecule-1 in the bronchial mucosa in steady-state and allergen-induced asthma. J Allergy Clin Immunol (1993) 1.14
Granulocyte-macrophage colony-stimulating factor expression in induced sputum and bronchial mucosa in asthma and COPD. Thorax (2009) 1.14
Are there differences between the secretion characteristics of NGF and BDNF? Implications for the modulatory role of neurotrophins in activity-dependent neuronal plasticity. Microsc Res Tech (1999) 1.14
Asthma control during and after cessation of regular beta 2-agonist treatment. Am Rev Respir Dis (1993) 1.13
Inflammatory cell microlocalisation and airway dysfunction: cause and effect? Eur Respir J (2007) 1.11