Activation of human lung mast cells by monomeric immunoglobulin E.

Regulation of mast cell responses in health and disease. Crit Rev Immunol (2011) 1.50

Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: cooperative roles for CADM1, stem cell factor, and IL-6. J Immunol (2008) 1.23

Ablation of tumor progression locus 2 promotes a type 2 Th cell response in Ovalbumin-immunized mice. J Immunol (2009) 0.95

IgE alone promotes human lung mast cell survival through the autocrine production of IL-6. BMC Immunol (2008) 0.94

Most Highly Cytokinergic IgEs Have Polyreactivity to Autoantigens. Allergy Asthma Immunol Res (2012) 0.93

Polyclonal IgE induces mast cell survival and cytokine production. Allergol Int (2009) 0.92

A novel FcεRIβ-chain truncation regulates human mast cell proliferation and survival. FASEB J (2010) 0.89

Cytokinergic IgE Action in Mast Cell Activation. Front Immunol (2012) 0.88

Asthma: eosinophil disease, mast cell disease, or both? Allergy Asthma Clin Immunol (2008) 0.88

Airway smooth muscle proliferation and survival is not modulated by mast cells. Clin Exp Allergy (2009) 0.87

Cultured peripheral blood mast cells from chronic idiopathic urticaria patients spontaneously degranulate upon IgE sensitization: Relationship to expression of Syk and SHIP-2. Clin Immunol (2009) 0.82

Silibinin inhibits the production of pro-inflammatory cytokines through inhibition of NF-κB signaling pathway in HMC-1 human mast cells. Inflamm Res (2013) 0.81

Britanin Suppresses IgE/Ag-Induced Mast Cell Activation by Inhibiting the Syk Pathway. Biomol Ther (Seoul) (2014) 0.80

Do mast cells link obesity and asthma? Allergy (2012) 0.80

Mast cells in airway diseases and interstitial lung disease. Eur J Pharmacol (2015) 0.79

Houttuynia cordata Thunb inhibits the production of pro-inflammatory cytokines through inhibition of the NFκB signaling pathway in HMC-1 human mast cells. Mol Med Rep (2013) 0.79

IgE-dependent sensitization increases responsiveness to LPS but does not modify development of endotoxin tolerance in mast cells. Inflamm Res (2010) 0.78

Mechanism of the antigen-independent cytokinergic SPE-7 IgE activation of human mast cells in vitro. Sci Rep (2015) 0.77

Activation of human lung mast cells by monomeric immunoglobulin E. Eur Respir J (2005) 0.75

Rethinking the role of immunoglobulin E and its high-affinity receptor: new insights into allergy and beyond. Int Arch Allergy Immunol (2014) 0.75

IgE by itself affects mature rat mast cell preformed and de novo-synthesized mediator release and amplifies mast cell migratory response. PLoS One (2013) 0.75

Orai and TRPC channel characterization in FcεRI-mediated calcium signaling and mediator secretion in human mast cells. Physiol Rep (2017) 0.75

IgE Trimers Drive SPE-7 Cytokinergic Activity. Sci Rep (2017) 0.75

CHARMM: the biomolecular simulation program. J Comput Chem (2009) 27.71

Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon Cre-mediated excision. Genesis (2001) 12.85

Global burden of obesity in 2005 and projections to 2030. Int J Obes (Lond) (2008) 9.45

A multidrug resistance transporter from human MCF-7 breast cancer cells. Proc Natl Acad Sci U S A (1998) 6.47

Heterogeneity of coronary heart disease risk factors in Indian, Pakistani, Bangladeshi, and European origin populations: cross sectional study. BMJ (1999) 6.40

Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication. Cell (2001) 5.93

Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomas. Proc Natl Acad Sci U S A (2000) 5.49

Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA. Nature (2000) 4.63

Redesigning an FKBP-ligand interface to generate chemical dimerizers with novel specificity. Proc Natl Acad Sci U S A (1998) 3.88

Non-eosinophilic corticosteroid unresponsive asthma. Lancet (1999) 3.25

Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein. EMBO J (2001) 3.23

Hardness, softness, and the fukui function in the electronic theory of metals and catalysis. Proc Natl Acad Sci U S A (1985) 3.12

Transformation of MutL by ATP binding and hydrolysis: a switch in DNA mismatch repair. Cell (1999) 2.91

Short-window spectral analysis of cortical event-related potentials by adaptive multivariate autoregressive modeling: data preprocessing, model validation, and variability assessment. Biol Cybern (2000) 2.81

Polyglutamine aggregation behavior in vitro supports a recruitment mechanism of cytotoxicity. J Mol Biol (2001) 2.80

Eosinophilic airway inflammation and exacerbations of COPD: a randomised controlled trial. Eur Respir J (2007) 2.78

The use of global and local molecular parameters for the analysis of the gas-phase basicity of amines. J Am Chem Soc (1986) 2.64

Analysis of induced sputum in adults with asthma: identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids. Thorax (2002) 2.63

Expression of the TMPRSS2:ERG fusion gene predicts cancer recurrence after surgery for localised prostate cancer. Br J Cancer (2007) 2.62

Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repair. Mol Cell (2001) 2.46

Crystal structure and ATPase activity of MutL: implications for DNA repair and mutagenesis. Cell (1998) 2.46

CCR7 expression and memory T cell diversity in humans. J Immunol (2001) 2.42

Modulation of tRNA(iMet), eIF-2, and eIF-2B expression shows that GCN4 translation is inversely coupled to the level of eIF-2.GTP.Met-tRNA(iMet) ternary complexes. Mol Cell Biol (1995) 2.37

Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein. Cancer Res (2000) 2.32

Reovirus as an oncolytic agent against experimental human malignant gliomas. J Natl Cancer Inst (2001) 2.27

Paradoxical bronchoconstriction in asthmatic patients after salmeterol by metered dose inhaler. BMJ (1992) 2.25

Mutations of acidic residues in RAG1 define the active site of the V(D)J recombinase. Genes Dev (1999) 2.24

Survival among women with triple receptor-negative breast cancer and brain metastases. Ann Oncol (2009) 2.21

Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs. J Allergy Clin Immunol (2012) 2.17

A clinician-driven automated system for integration of pharmacogenetic interpretations into an electronic medical record. Clin Pharmacol Ther (2012) 2.12

A versatile synthetic dimerizer for the regulation of protein-protein interactions. Proc Natl Acad Sci U S A (1997) 2.04

Crystal structure of the Xrcc4 DNA repair protein and implications for end joining. EMBO J (2000) 1.94

Sputum IL-5 concentration is associated with a sputum eosinophilia and attenuated by corticosteroid therapy in COPD. Respiration (2009) 1.92

Medium-chain acyl-CoA dehydrogenase deficiency in children with non-ketotic hypoglycemia and low carnitine levels. Pediatr Res (1983) 1.91

Homologous segments in three subunits of the guanine nucleotide exchange factor eIF2B mediate translational regulation by phosphorylation of eIF2. Mol Cell Biol (1997) 1.89

Structural basis for MutH activation in E.coli mismatch repair and relationship of MutH to restriction endonucleases. EMBO J (1998) 1.84

Linearly polarized emission from colloidal semiconductor quantum rods. Science (2001) 1.82

Genetic polymorphism of inosine triphosphate pyrophosphatase is a determinant of mercaptopurine metabolism and toxicity during treatment for acute lymphoblastic leukemia. Clin Pharmacol Ther (2008) 1.82

Sputum eosinophilia and the short term response to inhaled mometasone in chronic obstructive pulmonary disease. Thorax (2005) 1.81

Macrophages within NSCLC tumour islets are predominantly of a cytotoxic M1 phenotype associated with extended survival. Eur Respir J (2009) 1.80

mu Opioid receptor knockout in mice: effects on ligand-induced analgesia and morphine lethality. Brain Res Mol Brain Res (1998) 1.78

Profiling of sputum inflammatory mediators in asthma and chronic obstructive pulmonary disease. Respiration (2011) 1.78

Comparison of airway immunopathology of eosinophilic bronchitis and asthma. Thorax (2003) 1.75

Long-term effects of a randomised trial of a 6-year lifestyle intervention in impaired glucose tolerance on diabetes-related microvascular complications: the China Da Qing Diabetes Prevention Outcome Study. Diabetologia (2010) 1.68

Direct association with and dephosphorylation of Jak2 kinase by the SH2-domain-containing protein tyrosine phosphatase SHP-1. Mol Cell Biol (1996) 1.68

Expression of chemokine receptors by lung T cells from normal and asthmatic subjects. J Immunol (2001) 1.67

Density-functional theory of the electronic structure of molecules. Annu Rev Phys Chem (1995) 1.64

Concordance of DMET plus genotyping results with those of orthogonal genotyping methods. Clin Pharmacol Ther (2012) 1.62

Fragile X gene instability: anchoring AGGs and linked microsatellites. Am J Hum Genet (1995) 1.61

New insights into the role of the mast cell in asthma. Clin Exp Allergy (2003) 1.61

The long-acting beta2-agonist salmeterol xinafoate: effects on airway inflammation in asthma. Eur Respir J (1999) 1.58

The pharmacology of bimatoprost (Lumigan). Surv Ophthalmol (2001) 1.54

The use of exhaled nitric oxide concentration to identify eosinophilic airway inflammation: an observational study in adults with asthma. Clin Exp Allergy (2005) 1.52

Cloning of a novel phosphoprotein regulated by colony-stimulating factor 1 shares a domain with the Drosophila disabled gene product. J Biol Chem (1995) 1.52

Expression of CCR8 is increased in asthma. Clin Exp Allergy (2010) 1.51

Presumptive stressful life events scale (psles) - a new stressful life events scale for use in India. Indian J Psychiatry (1984) 1.51

Insulin like growth factor binding protein-7 reduces growth of human breast cancer cells and xenografted tumors. Breast Cancer Res Treat (2010) 1.50

A novel phosphotyrosine motif with a critical amino acid at position -2 for the SH2 domain-mediated activation of the tyrosine phosphatase SHP-1. J Biol Chem (1997) 1.50

Elevated serum antibodies against insulin-like growth factor-binding protein-2 allow detecting early-stage cancers: evidences from glioma and colorectal carcinoma studies. Ann Oncol (2012) 1.49

New insights into the relationship between airway inflammation and asthma. Clin Sci (Lond) (2002) 1.47

Atypical multidrug resistance: breast cancer resistance protein messenger RNA expression in mitoxantrone-selected cell lines. J Natl Cancer Inst (1999) 1.46

Homeostatic regulation of copper uptake in yeast via direct binding of MAC1 protein to upstream regulatory sequences of FRE1 and CTR1. J Biol Chem (1997) 1.45

Cancer-associated somatic DICER1 hotspot mutations cause defective miRNA processing and reverse-strand expression bias to predominantly mature 3p strands through loss of 5p strand cleavage. J Pathol (2013) 1.45

Aspartame is no more likely than placebo to cause urticaria/angioedema: results of a multicenter, randomized, double-blind, placebo-controlled, crossover study. J Allergy Clin Immunol (1993) 1.44

Quantum mechanics simulation of protein dynamics on long timescale. Proteins (2001) 1.42

The metabolic effects of once daily extended-release metformin in patients with type 2 diabetes: a multicentre study. Int J Clin Pract (2008) 1.40

Site-directed mutagenesis of the hinge region of nisinZ and properties of nisinZ mutants. Appl Microbiol Biotechnol (2004) 1.40

miR-21 is a key therapeutic target for renal injury in a mouse model of type 2 diabetes. Diabetologia (2013) 1.39

Functional KCa3.1 K+ channels are required for human lung mast cell migration. Thorax (2006) 1.39

Obesity, coronary heart disease risk factors and diabetes in Chinese: an approach to the criteria of obesity in the Chinese population. Obes Rev (2002) 1.37

Comparison of vildagliptin and acarbose monotherapy in patients with Type 2 diabetes: a 24-week, double-blind, randomized trial. Diabet Med (2008) 1.37

Interleukin-4 and -13 expression is co-localized to mast cells within the airway smooth muscle in asthma. Clin Exp Allergy (2003) 1.37

PU box-binding transcription factors and a POU domain protein cooperate in the Epstein-Barr virus (EBV) nuclear antigen 2-induced transactivation of the EBV latent membrane protein 1 promoter. J Gen Virol (1995) 1.36

An ATF/CRE element mediates both EBNA2-dependent and EBNA2-independent activation of the Epstein-Barr virus LMP1 gene promoter. J Virol (1998) 1.35

Structure and function of the N-terminal 40 kDa fragment of human PMS2: a monomeric GHL ATPase. EMBO J (2001) 1.35

ARID5B SNP rs10821936 is associated with risk of childhood acute lymphoblastic leukemia in blacks and contributes to racial differences in leukemia incidence. Leukemia (2010) 1.34

The Saccharomyces cerevisiae Rheb G-protein is involved in regulating canavanine resistance and arginine uptake. J Biol Chem (2000) 1.33

Triphalangeal thumb-polysyndactyly syndrome and syndactyly type IV are caused by genomic duplications involving the long range, limb-specific SHH enhancer. J Med Genet (2008) 1.33

Identification of a motif in the carboxyl terminus of CXCR2 that is involved in adaptin 2 binding and receptor internalization. Biochemistry (2001) 1.32

The science of pterygia. Br J Ophthalmol (2009) 1.31

Special topics--Mitigation of methane and nitrous oxide emissions from animal operations: I. A review of enteric methane mitigation options. J Anim Sci (2013) 1.30

Asymmetric recognition of DNA local distortion. Structure-based functional studies of eukaryotic Msh2-Msh6. J Biol Chem (2001) 1.28

Respiratory infections and the autumn increase in asthma morbidity. Eur Respir J (1996) 1.27

Genome-wide association study to identify genetic determinants of severe asthma. Thorax (2012) 1.27

Expression and clinicopathological significance of oestrogen-responsive ezrin-radixin-moesin-binding phosphoprotein 50 in breast cancer. Histopathology (2007) 1.27

Reciprocal inhibition of mouse leukemia virus infection by Fv-1 allele cell extracts. Proc Natl Acad Sci U S A (1974) 1.27

1,25-Dihydroxyvitamin D3 and all-trans-retinoic acid sensitize breast cancer cells to chemotherapy-induced cell death. Cancer Res (2000) 1.26

Adhesion of human lung mast cells to bronchial epithelium: evidence for a novel carbohydrate-mediated mechanism. J Leukoc Biol (2000) 1.24

Polychromatic X-ray microdiffraction studies of mesoscale structure and dynamics. J Synchrotron Radiat (2005) 1.24

Microbial oxidation of oleic acid. Appl Environ Microbiol (1992) 1.22

MGSA/GRO-mediated melanocyte transformation involves induction of Ras expression. Oncogene (2000) 1.20

Idiopathic chronic cough: association with organ specific autoimmune disease and bronchoalveolar lymphocytosis. Thorax (2003) 1.19

Raman spectral evidence for hydration forces between collagen triple helices. Proc Natl Acad Sci U S A (1997) 1.19

Oligomerization of a MutS mismatch repair protein from Thermus aquaticus. J Biol Chem (1999) 1.18

Genetic tuning of the novel avian influenza A(H7N9) virus during interspecies transmission, China, 2013. Euro Surveill (2014) 1.16

[The identification of recombinant HIV-1 strains in IDUs in southwest and northwest China]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi (1999) 1.16

Development and performance evaluation of novel chemiluminescence assays for detection of anti-PR3 and anti-MPO antibodies. Clin Chim Acta (2012) 1.16