Published in OMICS on August 01, 2010
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Exploring the structural diversity of mammalian carbohydrates ("glycospace") by statistical databank analysis. ACS Chem Biol (2007) 2.42
Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria. Nature (2002) 2.31
Oligosaccharide and glycoprotein microarrays as tools in HIV glycobiology; glycan-dependent gp120/protein interactions. Chem Biol (2004) 2.22
Natural Sphingomonas glycolipids vary greatly in their ability to activate natural killer T cells. Chem Biol (2008) 1.95
The use of carbohydrate microarrays to study carbohydrate-cell interactions and to detect pathogens. Chem Biol (2004) 1.91
Potentiation of fibroblast growth factor activity by synthetic heparin oligosaccharide glycodendrimers. Chem Biol (2007) 1.89
Continuous-flow synthesis of the anti-malaria drug artemisinin. Angew Chem Int Ed Engl (2012) 1.85
Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides. J Biol Chem (2002) 1.71
Synthetic GPI array to study antitoxic malaria response. Nat Chem Biol (2008) 1.67
Microreactors as tools for synthetic chemists-the chemists' round-bottomed flask of the 21st century? Chemistry (2006) 1.56
Preparation and use of microarrays containing synthetic heparin oligosaccharides for the rapid analysis of heparin-protein interactions. Chemistry (2006) 1.54
Chemical approaches to define the structure-activity relationship of heparin-like glycosaminoglycans. Chem Biol (2005) 1.39
Profiling heparin-chemokine interactions using synthetic tools. ACS Chem Biol (2007) 1.38
Probing protein-carbohydrate interactions with microarrays of synthetic oligosaccharides. Chembiochem (2004) 1.38
Total synthesis of antigen bacillus anthracis tetrasaccharide--creation of an anthrax vaccine candidate. Angew Chem Int Ed Engl (2005) 1.36
Microarrays of synthetic heparin oligosaccharides. J Am Chem Soc (2006) 1.35
Tools for glycomics: mapping interactions of carbohydrates in biological systems. Chembiochem (2004) 1.32
Multisite and multivalent binding between cyanovirin-N and branched oligomannosides: calorimetric and NMR characterization. Chem Biol (2002) 1.32
Modular synthesis of heparin oligosaccharides. Chemistry (2003) 1.30
The affinity of the FimH fimbrial adhesin is receptor-driven and quasi-independent of Escherichia coli pathotypes. Mol Microbiol (2006) 1.28
Natural cytotoxicity receptors NKp30, NKp44 and NKp46 bind to different heparan sulfate/heparin sequences. J Proteome Res (2009) 1.27
Synthesis and biological activity of largazole and derivatives. Angew Chem Int Ed Engl (2008) 1.25
Asymmetric reactions in continuous flow. Beilstein J Org Chem (2009) 1.23
Caenorhabditis elegans N-glycan core beta-galactoside confers sensitivity towards nematotoxic fungal galectin CGL2. PLoS Pathog (2010) 1.23
Automated synthesis of the tumor-associated carbohydrate antigens Gb-3 and Globo-H: incorporation of alpha-galactosidic linkages. J Am Chem Soc (2007) 1.21
Anti-carbohydrate antibodies for the detection of anthrax spores. Angew Chem Int Ed Engl (2006) 1.19
Multiple modes of binding enhance the affinity of DC-SIGN for high mannose N-linked glycans found on viral glycoproteins. J Biol Chem (2006) 1.17
Glycomics, glycoproteomics and the immune system. Curr Opin Chem Biol (2012) 1.17
A mannan binding lectin is involved in cell-cell attachment in a toxic strain of Microcystis aeruginosa. Mol Microbiol (2006) 1.16
Carbohydrate arrays as tools for research and diagnostics. Chem Soc Rev (2008) 1.15
Highly efficient continuous flow reactions using singlet oxygen as a "green" reagent. Org Lett (2011) 1.13
In vitro imaging and in vivo liver targeting with carbohydrate capped quantum dots. J Am Chem Soc (2009) 1.12
Synthesis of a sialic acid alpha(2-3) galactose building block and its use in a linear synthesis of sialyl Lewis X. Org Lett (2007) 1.10
Oligosaccharide synthesis in microreactors. Org Lett (2007) 1.10
Carbohydrate arrays as tools for glycomics. Angew Chem Int Ed Engl (2002) 1.10
Control of Golgi morphology and function by Sed5 t-SNARE phosphorylation. Mol Biol Cell (2005) 1.10
Detection of bacteria with carbohydrate-functionalized fluorescent polymers. J Am Chem Soc (2004) 1.09
Alpha1,4GlcNAc-capped mucin-type O-glycan inhibits cholesterol alpha-glucosyltransferase from Helicobacter pylori and suppresses H. pylori growth. Glycobiology (2008) 1.09
Quantitative mapping of glycoprotein micro-heterogeneity and macro-heterogeneity: an evaluation of mass spectrometry signal strengths using synthetic peptides and glycopeptides. J Mass Spectrom (2013) 1.08
Automated solid-phase synthesis of protected oligosaccharides containing beta-mannosidic linkages. Chemistry (2008) 1.07
Expression cloning of cholesterol alpha-glucosyltransferase, a unique enzyme that can be inhibited by natural antibiotic gastric mucin O-glycans, from Helicobacter pylori. Biochem Biophys Res Commun (2006) 1.06
Molecular basis of S-layer glycoprotein glycan biosynthesis in Geobacillus stearothermophilus. J Biol Chem (2008) 1.05
Carbohydrates as the next frontier in pharmaceutical research. Chemistry (2005) 1.05
Applying flow chemistry: methods, materials, and multistep synthesis. J Org Chem (2013) 1.05
Automated solid-phase synthesis of β-mannuronic acid alginates. Angew Chem Int Ed Engl (2012) 1.02
Recognition of mannosylated ligands and influenza A virus by human surfactant protein D: contributions of an extended site and residue 343. Biochemistry (2009) 1.02
The novel fold of scytovirin reveals a new twist for antiviral entry inhibitors. J Mol Biol (2007) 1.02
Carbohydrate-mediated targeting of antigen to dendritic cells leads to enhanced presentation of antigen to T cells. Chembiochem (2008) 1.00
Semisynthesis of a glycosylphosphatidylinositol-anchored prion protein. Angew Chem Int Ed Engl (2008) 1.00
Chemoenzymatic synthesis of differentially protected 3-deoxysugars. Nat Chem (2010) 1.00
Continuous synthesis and purification by direct coupling of a flow reactor with simulated moving-bed chromatography. Angew Chem Int Ed Engl (2012) 0.99
Applications of synthetic carbohydrates to chemical biology. Curr Opin Chem Biol (2010) 0.99
Combined approaches to the synthesis and study of glycoproteins. ACS Chem Biol (2009) 0.99
Rapid synthesis of a glycosylphosphatidylinositol-based malaria vaccine using automated solid-phase oligosaccharide synthesis. J Am Chem Soc (2002) 0.98
Microreactor-based reaction optimization in organic chemistry--glycosylation as a challenge. Chem Commun (Camb) (2004) 0.97
Efficient installation of beta-mannosides using a dehydrative coupling strategy. Org Lett (2005) 0.97
The promise of glycomics, glycan arrays and carbohydrate-based vaccines. Immunopharmacol Immunotoxicol (2010) 0.97
Chemical synthesis of all phosphatidylinositol mannoside (PIM) glycans from Mycobacterium tuberculosis. J Am Chem Soc (2008) 0.97
Anthrax spore detection by a luminex assay based on monoclonal antibodies that recognize anthrose-containing oligosaccharides. Clin Vaccine Immunol (2010) 0.96
Aminoglycoside microarrays to study antibiotic resistance. Angew Chem Int Ed Engl (2004) 0.95
Linear synthesis of the tumor-associated carbohydrate antigens Globo-H, SSEA-3, and Gb3. J Org Chem (2002) 0.95
Synthesis of a core arabinomannan oligosaccharide of Mycobacterium tuberculosis. J Org Chem (2006) 0.94
The N-glycolyl form of mouse sialyl Lewis X is recognized by selectins but not by HECA-452 and FH6 antibodies that were raised against human cells. Glycoconj J (2008) 0.94
Deciphering the glycosaminoglycan code with the help of microarrays. Mol Biosyst (2008) 0.93
Synthesis of iduronic acid building blocks for the modular assembly of glycosaminoglycans. J Org Chem (2003) 0.93
Hexameric supramolecular scaffold orients carbohydrates to sense bacteria. J Am Chem Soc (2011) 0.93
Continuous flow thermolysis of azidoacrylates for the synthesis of heterocycles and pharmaceutical intermediates. Chem Commun (Camb) (2010) 0.93
A stereochemical surprise at the late stage of the synthesis of fully N-differentiated heparin oligosaccharides containing amino, acetamido, and N-sulfonate groups. J Org Chem (2004) 0.93
Mechanical compressibility of the glycosylphosphatidylinositol (GPI) anchor backbone governed by independent glycosidic linkages. J Am Chem Soc (2012) 0.92
Automated solid-phase synthesis of protected tumor-associated antigen and blood group determinant oligosaccharides. Angew Chem Int Ed Engl (2004) 0.92
Recent advances in carbohydrate-based vaccines. Curr Opin Chem Biol (2009) 0.92
Molecular analysis of carbohydrate-antibody interactions: case study using a Bacillus anthracis tetrasaccharide. J Am Chem Soc (2010) 0.91
Total synthesis of phosphatidylinositol mannosides of Mycobacterium tuberculosis. J Am Chem Soc (2006) 0.91
Differential adeno-associated virus serotype-specific interaction patterns with synthetic heparins and other glycans. J Virol (2013) 0.91
Plasmodium falciparum glycosylphosphatidylinositol toxin interacts with the membrane of non-parasitized red blood cells: a putative mechanism contributing to malaria anemia. Microbes Infect (2008) 0.90
2009 Claude S. Hudson Award in Carbohydrate Chemistry. Carbohydrates: a frontier in medicinal chemistry. J Med Chem (2009) 0.90
A possible oligosaccharide-conjugate vaccine candidate for Clostridium difficile is antigenic and immunogenic. Chem Biol (2011) 0.90
Cantilever array sensors detect specific carbohydrate-protein interactions with picomolar sensitivity. ACS Nano (2011) 0.90
Synthesis of a hexasaccharide repeating unit from Bacillus anthracis vegetative cell walls. Org Lett (2008) 0.90
MyD88/IL-18-dependent pathways rather than TLRs control early parasitaemia in non-lethal Plasmodium yoelii infection. Microbes Infect (2008) 0.90
Automated solid-phase synthesis of chondroitin sulfate glycosaminoglycans. Angew Chem Int Ed Engl (2013) 0.89
Carbohydrate diversity: synthesis of glycoconjugates and complex carbohydrates. Curr Opin Biotechnol (2004) 0.89
Microarrays of heparin oligosaccharides obtained by nitrous acid depolymerization of isolated heparin. Chem Commun (Camb) (2006) 0.89
On one leg: trehalose monoesters activate macrophages in a Mincle-dependant manner. Chembiochem (2014) 0.89
Helicobacter pylori cholesteryl α-glucosides contribute to its pathogenicity and immune response by natural killer T cells. PLoS One (2013) 0.88
Heparan sulfate proteoglycans containing a glypican 5 core and 2-O-sulfo-iduronic acid function as Sonic Hedgehog co-receptors to promote proliferation. J Biol Chem (2013) 0.88
The C-Type Lectin Receptor SIGNR3 Binds to Fungi Present in Commensal Microbiota and Influences Immune Regulation in Experimental Colitis. Front Immunol (2013) 0.88
Surface characterization of carbohydrate microarrays. Langmuir (2010) 0.88
Aminoglycoside microarrays to explore interactions of antibiotics with RNAs and proteins. Chemistry (2004) 0.88
Enhancement of the immunogenicity of synthetic carbohydrates by conjugation to virosomes: a leishmaniasis vaccine candidate. ACS Chem Biol (2006) 0.88
Carbohydrate-lectin recognition of sequence-defined heteromultivalent glycooligomers. J Am Chem Soc (2014) 0.88
Carbohydrate microarrays as tools in HIV glycobiology. Curr Pharm Des (2007) 0.88
Diversity-oriented synthesis of inner core oligosaccharides of the lipopolysaccharide of pathogenic Gram-negative bacteria. J Am Chem Soc (2013) 0.88
Recent advances and future challenges in glycan microarray technology. Methods Mol Biol (2012) 0.87
Defined presentation of carbohydrates on a duplex DNA scaffold. Chembiochem (2011) 0.87
Automated polysaccharide synthesis: assembly of a 30mer mannoside. Angew Chem Int Ed Engl (2013) 0.87