Published in Chem Commun (Camb) on December 17, 2004
Microgram-scale testing of reaction conditions in solution using nanoliter plugs in microfluidics with detection by MALDI-MS. J Am Chem Soc (2006) 1.81
Microfluidics for drug discovery and development: from target selection to product lifecycle management. Drug Discov Today (2007) 1.71
Development of an automated microfluidic reaction platform for multidimensional screening: reaction discovery employing bicyclo[3.2.1]octanoid scaffolds. J Org Chem (2009) 1.34
The past, present and potential for microfluidic reactor technology in chemical synthesis. Nat Chem (2013) 1.25
Rapid catalyst screening by a continuous-flow microreactor interfaced with ultra-high-pressure liquid chromatography. J Org Chem (2010) 0.82
Automated solid-phase synthesis of oligosaccharides containing sialic acids. Beilstein J Org Chem (2015) 0.80
Strategic Application of Residence-Time Control in Continuous-Flow Reactors. ChemistryOpen (2015) 0.75
Cells on chips. Nature (2006) 8.40
Exploring the structural diversity of mammalian carbohydrates ("glycospace") by statistical databank analysis. ACS Chem Biol (2007) 2.42
A vector-free microfluidic platform for intracellular delivery. Proc Natl Acad Sci U S A (2013) 2.40
Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria. Nature (2002) 2.31
Oligosaccharide and glycoprotein microarrays as tools in HIV glycobiology; glycan-dependent gp120/protein interactions. Chem Biol (2004) 2.22
Microfluidic shear devices for quantitative analysis of cell adhesion. Anal Chem (2004) 1.95
Natural Sphingomonas glycolipids vary greatly in their ability to activate natural killer T cells. Chem Biol (2008) 1.95
The use of carbohydrate microarrays to study carbohydrate-cell interactions and to detect pathogens. Chem Biol (2004) 1.91
Design and global optimization of high-efficiency thermophotovoltaic systems. Opt Express (2010) 1.91
Potentiation of fibroblast growth factor activity by synthetic heparin oligosaccharide glycodendrimers. Chem Biol (2007) 1.89
Continuous-flow synthesis of the anti-malaria drug artemisinin. Angew Chem Int Ed Engl (2012) 1.85
An integrated microreactor system for self-optimization of a Heck reaction: from micro- to mesoscale flow systems. Angew Chem Int Ed Engl (2010) 1.77
Multiphase microfluidics: from flow characteristics to chemical and materials synthesis. Lab Chip (2006) 1.74
Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides. J Biol Chem (2002) 1.71
Synthetic GPI array to study antitoxic malaria response. Nat Chem Biol (2008) 1.67
A microfluidic electroporation device for cell lysis. Lab Chip (2004) 1.66
Transport and reaction in microscale segmented gas-liquid flow. Lab Chip (2004) 1.64
Microreactors as tools for synthetic chemists-the chemists' round-bottomed flask of the 21st century? Chemistry (2006) 1.56
Preparation and use of microarrays containing synthetic heparin oligosaccharides for the rapid analysis of heparin-protein interactions. Chemistry (2006) 1.54
Deciding whether to go with the flow: evaluating the merits of flow reactors for synthesis. Angew Chem Int Ed Engl (2011) 1.51
Integrated microreactors for reaction automation: new approaches to reaction development. Annu Rev Anal Chem (Palo Alto Calif) (2010) 1.43
Multistep continuous-flow microchemical synthesis involving multiple reactions and separations. Angew Chem Int Ed Engl (2007) 1.42
Synthesis of micro and nanostructures in microfluidic systems. Chem Soc Rev (2010) 1.40
Chemical approaches to define the structure-activity relationship of heparin-like glycosaminoglycans. Chem Biol (2005) 1.39
Profiling heparin-chemokine interactions using synthetic tools. ACS Chem Biol (2007) 1.38
Probing protein-carbohydrate interactions with microarrays of synthetic oligosaccharides. Chembiochem (2004) 1.38
Micromixing of miscible liquids in segmented gas-liquid flow. Langmuir (2005) 1.36
Total synthesis of antigen bacillus anthracis tetrasaccharide--creation of an anthrax vaccine candidate. Angew Chem Int Ed Engl (2005) 1.36
Microarrays of synthetic heparin oligosaccharides. J Am Chem Soc (2006) 1.35
Development of an automated microfluidic reaction platform for multidimensional screening: reaction discovery employing bicyclo[3.2.1]octanoid scaffolds. J Org Chem (2009) 1.34
Flow-induced deformation of shallow microfluidic channels. Lab Chip (2006) 1.34
Tools for glycomics: mapping interactions of carbohydrates in biological systems. Chembiochem (2004) 1.32
Multisite and multivalent binding between cyanovirin-N and branched oligomannosides: calorimetric and NMR characterization. Chem Biol (2002) 1.32
Modular synthesis of heparin oligosaccharides. Chemistry (2003) 1.30
The affinity of the FimH fimbrial adhesin is receptor-driven and quasi-independent of Escherichia coli pathotypes. Mol Microbiol (2006) 1.28
Natural cytotoxicity receptors NKp30, NKp44 and NKp46 bind to different heparan sulfate/heparin sequences. J Proteome Res (2009) 1.27
Microfluidic synthesis of colloidal silica. Langmuir (2004) 1.23
Asymmetric reactions in continuous flow. Beilstein J Org Chem (2009) 1.23
Caenorhabditis elegans N-glycan core beta-galactoside confers sensitivity towards nematotoxic fungal galectin CGL2. PLoS Pathog (2010) 1.23
Continuous dielectrophoretic size-based particle sorting. Anal Chem (2006) 1.21
Automated synthesis of the tumor-associated carbohydrate antigens Gb-3 and Globo-H: incorporation of alpha-galactosidic linkages. J Am Chem Soc (2007) 1.21
Anti-carbohydrate antibodies for the detection of anthrax spores. Angew Chem Int Ed Engl (2006) 1.19
Multiple modes of binding enhance the affinity of DC-SIGN for high mannose N-linked glycans found on viral glycoproteins. J Biol Chem (2006) 1.17
Glycomics, glycoproteomics and the immune system. Curr Opin Chem Biol (2012) 1.17
A mannan binding lectin is involved in cell-cell attachment in a toxic strain of Microcystis aeruginosa. Mol Microbiol (2006) 1.16
End-to-end continuous manufacturing of pharmaceuticals: integrated synthesis, purification, and final dosage formation. Angew Chem Int Ed Engl (2013) 1.15
Carbohydrate arrays as tools for research and diagnostics. Chem Soc Rev (2008) 1.15
Microchemical systems for continuous-flow synthesis. Lab Chip (2009) 1.14
Microfluidics-based assessment of cell deformability. Anal Chem (2012) 1.13
Highly efficient continuous flow reactions using singlet oxygen as a "green" reagent. Org Lett (2011) 1.13
In vitro imaging and in vivo liver targeting with carbohydrate capped quantum dots. J Am Chem Soc (2009) 1.12
Synthesis of a sialic acid alpha(2-3) galactose building block and its use in a linear synthesis of sialyl Lewis X. Org Lett (2007) 1.10
Oligosaccharide synthesis in microreactors. Org Lett (2007) 1.10
Carbohydrate arrays as tools for glycomics. Angew Chem Int Ed Engl (2002) 1.10
Detection of bacteria with carbohydrate-functionalized fluorescent polymers. J Am Chem Soc (2004) 1.09
Cell stimulus and lysis in a microfluidic device with segmented gas-liquid flow. Anal Chem (2005) 1.09
Development of a multiplexed microbioreactor system for high-throughput bioprocessing. Lab Chip (2005) 1.09
A microfabricated device for subcellular organelle sorting. Anal Chem (2004) 1.09
Alpha1,4GlcNAc-capped mucin-type O-glycan inhibits cholesterol alpha-glucosyltransferase from Helicobacter pylori and suppresses H. pylori growth. Glycobiology (2008) 1.09
Microfluidic based single cell microinjection. Lab Chip (2008) 1.08
Membrane-aerated microbioreactor for high-throughput bioprocessing. Biotechnol Bioeng (2004) 1.08
Quantitative mapping of glycoprotein micro-heterogeneity and macro-heterogeneity: an evaluation of mass spectrometry signal strengths using synthetic peptides and glycopeptides. J Mass Spectrom (2013) 1.08
Automated solid-phase synthesis of protected oligosaccharides containing beta-mannosidic linkages. Chemistry (2008) 1.07
Integrated continuous microfluidic liquid-liquid extraction. Lab Chip (2006) 1.07
Reactive polymer coatings: a first step toward surface engineering of microfluidic devices. Anal Chem (2003) 1.06
Microchemostat-microbial continuous culture in a polymer-based, instrumented microbioreactor. Lab Chip (2006) 1.06
Expression cloning of cholesterol alpha-glucosyltransferase, a unique enzyme that can be inhibited by natural antibiotic gastric mucin O-glycans, from Helicobacter pylori. Biochem Biophys Res Commun (2006) 1.06
Accelerating reactions with microreactors at elevated temperatures and pressures: profiling aminocarbonylation reactions. Angew Chem Int Ed Engl (2007) 1.06
Molecular basis of S-layer glycoprotein glycan biosynthesis in Geobacillus stearothermophilus. J Biol Chem (2008) 1.05
Carbohydrates as the next frontier in pharmaceutical research. Chemistry (2005) 1.05
Applying flow chemistry: methods, materials, and multistep synthesis. J Org Chem (2013) 1.05
A microfabricated gas-liquid segmented flow reactor for high-temperature synthesis: the case of CdSe quantum dots. Angew Chem Int Ed Engl (2005) 1.03
Automated solid-phase synthesis of β-mannuronic acid alginates. Angew Chem Int Ed Engl (2012) 1.02
Recognition of mannosylated ligands and influenza A virus by human surfactant protein D: contributions of an extended site and residue 343. Biochemistry (2009) 1.02
The novel fold of scytovirin reveals a new twist for antiviral entry inhibitors. J Mol Biol (2007) 1.02
Toward high-energy-density, high-efficiency, and moderate-temperature chip-scale thermophotovoltaics. Proc Natl Acad Sci U S A (2013) 1.01
Carbohydrate-mediated targeting of antigen to dendritic cells leads to enhanced presentation of antigen to T cells. Chembiochem (2008) 1.00
Chemoenzymatic synthesis of differentially protected 3-deoxysugars. Nat Chem (2010) 1.00
Semisynthesis of a glycosylphosphatidylinositol-anchored prion protein. Angew Chem Int Ed Engl (2008) 1.00
Continuous synthesis and purification by direct coupling of a flow reactor with simulated moving-bed chromatography. Angew Chem Int Ed Engl (2012) 0.99
Applications of synthetic carbohydrates to chemical biology. Curr Opin Chem Biol (2010) 0.99
Combined approaches to the synthesis and study of glycoproteins. ACS Chem Biol (2009) 0.99
Rapid synthesis of a glycosylphosphatidylinositol-based malaria vaccine using automated solid-phase oligosaccharide synthesis. J Am Chem Soc (2002) 0.98
Micro free-flow IEF enhanced by active cooling and functionalized gels. Electrophoresis (2006) 0.98
Investigation of indium phosphide nanocrystal synthesis using a high-temperature and high-pressure continuous flow microreactor. Angew Chem Int Ed Engl (2010) 0.98
Suzuki-Miyaura cross-coupling reactions in flow: multistep synthesis enabled by a microfluidic extraction. Angew Chem Int Ed Engl (2011) 0.97
Efficient installation of beta-mannosides using a dehydrative coupling strategy. Org Lett (2005) 0.97
Chemical synthesis of all phosphatidylinositol mannoside (PIM) glycans from Mycobacterium tuberculosis. J Am Chem Soc (2008) 0.97
The promise of glycomics, glycan arrays and carbohydrate-based vaccines. Immunopharmacol Immunotoxicol (2010) 0.97
Anthrax spore detection by a luminex assay based on monoclonal antibodies that recognize anthrose-containing oligosaccharides. Clin Vaccine Immunol (2010) 0.96
Aminoglycoside microarrays to study antibiotic resistance. Angew Chem Int Ed Engl (2004) 0.95
Microfluidic preparative free-flow isoelectric focusing: system optimization for protein complex separation. Anal Chem (2010) 0.95
Linear synthesis of the tumor-associated carbohydrate antigens Globo-H, SSEA-3, and Gb3. J Org Chem (2002) 0.95
Synthesis of a core arabinomannan oligosaccharide of Mycobacterium tuberculosis. J Org Chem (2006) 0.94
A clock reaction based on molybdenum blue. J Phys Chem A (2013) 0.94
The N-glycolyl form of mouse sialyl Lewis X is recognized by selectins but not by HECA-452 and FH6 antibodies that were raised against human cells. Glycoconj J (2008) 0.94
Deciphering the glycosaminoglycan code with the help of microarrays. Mol Biosyst (2008) 0.93
Hexameric supramolecular scaffold orients carbohydrates to sense bacteria. J Am Chem Soc (2011) 0.93