Published in Mol Med on April 14, 2010
Plasma butyrylcholinesterase regulates ghrelin to control aggression. Proc Natl Acad Sci U S A (2015) 0.99
Towards the identification of blood biomarkers for acute stroke in humans: a comprehensive systematic review. Br J Clin Pharmacol (2012) 0.99
Predicted overlapping microRNA regulators of acetylcholine packaging and degradation in neuroinflammation-related disorders. Front Mol Neurosci (2014) 0.96
An updated role of microRNA-124 in central nervous system disorders: a review. Front Cell Neurosci (2015) 0.94
Preclinical studies on neurobehavioral and neuromuscular effects of cocaine hydrolase gene therapy in mice. J Mol Neurosci (2013) 0.91
Decline in serum cholinesterase activities predicts 2-year major adverse cardiac events. Mol Med (2014) 0.90
Activation of the alternative NFκB pathway improves disease symptoms in a model of Sjogren's syndrome. PLoS One (2011) 0.89
Plasma acetylcholinesterase activity correlates with intracerebral β-amyloid load. Curr Alzheimer Res (2013) 0.87
Butyrylcholinesterase interactions with amylin may protect pancreatic cells in metabolic syndrome. J Cell Mol Med (2011) 0.80
Correlations between cholinesterase activity and cognitive scores in post-ischemic rats and patients with vascular dementia. Cell Mol Neurobiol (2011) 0.79
Fluoxetine induces vasodilatation of cerebral arterioles by co-modulating NO/muscarinic signalling. J Cell Mol Med (2012) 0.79
Dysregulated cholinergic network as a novel biomarker of poor prognostic in patients with head and neck squamous cell carcinoma. BMC Cancer (2015) 0.78
Reduced serum butyrylcholinesterase activity indicates severe systemic inflammation in critically ill patients. Mediators Inflamm (2015) 0.77
Quantum dot labeling of butyrylcholinesterase maintains substrate and inhibitor interactions and cell adherence features. ACS Chem Neurosci (2010) 0.77
Different sensitivities of rat skeletal muscles and brain to novel anti-cholinesterase agents, alkylammonium derivatives of 6-methyluracil (ADEMS). Br J Pharmacol (2011) 0.75
Immunomodulatory effects of nicotine on interleukin 1β activated human astrocytes and the role of cyclooxygenase 2 in the underlying mechanism. J Neuroinflammation (2016) 0.75
Identification and Functional Analysis of MicroRNAs in Mice following Focal Cerebral Ischemia Injury. Int J Mol Sci (2015) 0.75
Non-neuronal cholinergic activity is potentiated in myasthenia gravis. BMC Neurol (2017) 0.75
Choosing wisely - when to mend a broken heart with ECMO? Crit Care (2014) 0.75
Serum Total Cholinesterase Activity on Admission Is Associated with Disease Severity and Outcome in Patients with Traumatic Brain Injury. PLoS One (2015) 0.75
Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke (1993) 29.81
Heart disease and stroke statistics--2007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation (2006) 19.43
[Rapid physiological coagulation method in determination of fibrinogen]. Acta Haematol (1957) 12.36
Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation. Nature (2002) 12.09
Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature (2000) 11.49
Proinflammatory cytokines and early neurological worsening in ischemic stroke. Stroke (2000) 3.74
Acute stress facilitates long-lasting changes in cholinergic gene expression. Nature (1998) 3.46
Clinical efficacy of an automated high-sensitivity C-reactive protein assay. Clin Chem (1999) 2.35
MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase. Immunity (2009) 2.33
Systemic infection, inflammation and acute ischemic stroke. Neuroscience (2008) 2.03
Genetic predisposition to adverse consequences of anti-cholinesterases in 'atypical' BCHE carriers. Nat Med (1995) 1.87
Proinflammatory cytokines in serum of patients with acute cerebral ischemia: kinetics of secretion and relation to the extent of brain damage and outcome of disease. J Neurol Sci (1994) 1.48
DNA mutation associated with the human butyrylcholinesterase K-variant and its linkage to the atypical variant mutation and other polymorphic sites. Am J Hum Genet (1992) 1.36
Recommendation of measurement of erythrocyte sedimentation rate of human blood. Am J Clin Pathol (1977) 1.32
Interleukin-6 and interleukin-1 receptor antagonist in acute stroke. Ann Neurol (1995) 1.30
Leukocyte count predicts outcome after ischemic stroke: the Northern Manhattan Stroke Study. J Stroke Cerebrovasc Dis (2007) 1.23
Blood biomarkers in the diagnosis of ischemic stroke: a systematic review. Stroke (2008) 1.21
Cholinergic status modulations in human volunteers under acute inflammation. J Mol Med (Berl) (2007) 1.15
Depression and anxiety 3 months post stroke: prevalence and correlates. Arch Clin Neuropsychol (2007) 1.13
Acetylcholinesterase/paraoxonase genotype and expression predict anxiety scores in Health, Risk Factors, Exercise Training, and Genetics study. Proc Natl Acad Sci U S A (2004) 1.09
Inflammation, hemostatic markers, and antithrombotic agents in relation to long-term risk of new cardiovascular events in first-ever ischemic stroke patients. Stroke (2002) 1.04
It takes nerve to dampen inflammation. Nat Immunol (2005) 1.02
Neuroprotection by nicotine against hypoxia-induced apoptosis in cortical cultures involves activation of multiple nicotinic acetylcholine receptor subtypes. Mol Cell Neurosci (2003) 0.94
Inflammatory gene load is associated with enhanced inflammation and early carotid atherosclerosis in smokers. Stroke (2004) 0.88
Boosting the brain's ability to block inflammation via microRNA-132. Immunity (2009) 0.88
Neuroprotective effect of donepezil, a nicotinic acetylcholine-receptor activator, on cerebral infarction in rats. Brain Res (2005) 0.84
The butyrylcholinesterase knockout mouse a research tool in the study of drug sensitivity, bio-distribution, obesity and Alzheimer's disease. Expert Opin Drug Metab Toxicol (2009) 0.82
Relation between butyrylcholinesterase K variant, paraoxonase 1 (PON1) Q and R and apolipoprotein E epsilon 4 genes in early-onset coronary artery disease. Clin Biochem (2002) 0.82
Myasthenia gravis: myasthenia vs. cholinergic crisis. Pediatr Emerg Care (2005) 0.81
Function of alternative splicing. Gene (2004) 5.95
Asymptomatic embolisation for prediction of stroke in the Asymptomatic Carotid Emboli Study (ACES): a prospective observational study. Lancet Neurol (2010) 4.01
Identifying subtle interrelated changes in functional gene categories using continuous measures of gene expression. Bioinformatics (2004) 2.47
Neutrophil/lymphocyte ratio is related to the severity of coronary artery disease and clinical outcome in patients undergoing angiography. Atherosclerosis (2012) 2.38
MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase. Immunity (2009) 2.33
The Stroke Riskometer(TM) App: validation of a data collection tool and stroke risk predictor. Int J Stroke (2014) 2.18
Burnout and risk of cardiovascular disease: evidence, possible causal paths, and promising research directions. Psychol Bull (2006) 2.01
Hyperglycemia and acute ischemic stroke. Isr Med Assoc J (2004) 1.97
Erythrocyte aggregation as a cause of slow flow in patients of acute coronary syndromes. Int J Cardiol (2011) 1.94
Does impaired cerebrovascular reactivity predict stroke risk in asymptomatic carotid stenosis? A prospective substudy of the asymptomatic carotid emboli study. Stroke (2011) 1.73
Grading carotid stenosis using ultrasonic methods. Stroke (2012) 1.70
Mortality and predictors of death 1 month and 3 years after first-ever ischemic stroke: data from the first national acute stroke Israeli survey (NASIS 2004). Neuroepidemiology (2009) 1.64
Relation of educational level to inflammation-sensitive biomarker level. Am J Cardiol (2008) 1.64
Predictive value of high sensitivity CRP in patients with diastolic heart failure. Int J Cardiol (2007) 1.63
Venous and arterial thrombosis following administration of intravenous immunoglobulins. Blood Coagul Fibrinolysis (2005) 1.60
RACK1 has the nerve to act: structure meets function in the nervous system. Prog Neurobiol (2006) 1.56
Ischemic stroke on awakening: patients' characteristics, outcomes and potential for reperfusion therapy. Neuroepidemiology (2012) 1.55
Alteration of the microRNA network during the progression of Alzheimer's disease. EMBO Mol Med (2013) 1.54
Burnout and risk of type 2 diabetes: a prospective study of apparently healthy employed persons. Psychosom Med (2006) 1.52
Impact of estimated glomerular filtration rate on vascular disease extent and adverse cardiovascular events in patients without chronic kidney disease. Can J Cardiol (2013) 1.52
Opsonization of apoptotic cells by autologous iC3b facilitates clearance by immature dendritic cells, down-regulates DR and CD86, and up-regulates CC chemokine receptor 7. J Exp Med (2002) 1.51
Chronic cholinergic imbalances promote brain diffusion and transport abnormalities. FASEB J (2005) 1.50
Inflammatory bowel disease is not associated with increased intimal media thickening. Am J Gastroenterol (2007) 1.50
A network-based method for predicting disease-causing genes. J Comput Biol (2009) 1.49
MicroRNA modulation of megakaryoblast fate involves cholinergic signaling. Leuk Res (2005) 1.49
Asthma in adventure travelers: a prospective study evaluating the occurrence and risk factors for acute exacerbations. Arch Intern Med (2002) 1.45
Virtues and woes of AChE alternative splicing in stress-related neuropathologies. Trends Neurosci (2006) 1.45
Attempted forced titration of blood pressure to <130/85 mm Hg in type 2 diabetic hypertensive patients in clinical practice: the diastolic cost. J Clin Hypertens (Greenwich) (2006) 1.41
Lessons learned from 2 years experience in intravenous thrombolysis for acute ischemic stroke in a single tertiary medical center. Isr Med Assoc J (2009) 1.39
Alternative splicing and neuritic mRNA translocation under long-term neuronal hypersensitivity. Science (2002) 1.39
The association between burnout, depression, anxiety, and inflammation biomarkers: C-reactive protein and fibrinogen in men and women. J Occup Health Psychol (2005) 1.31
Defects in pre-mRNA processing as causes of and predisposition to diseases. DNA Cell Biol (2002) 1.28
Heterogeneous nuclear ribonucleoprotein G regulates splice site selection by binding to CC(A/C)-rich regions in pre-mRNA. J Biol Chem (2009) 1.23
Partial aortic occlusion for cerebral perfusion augmentation: safety and efficacy of NeuroFlo in Acute Ischemic Stroke trial. Stroke (2011) 1.22
Combinatorial complexity of 5' alternative acetylcholinesterase transcripts and protein products. J Biol Chem (2004) 1.20
Plant-derived human butyrylcholinesterase, but not an organophosphorous-compound hydrolyzing variant thereof, protects rodents against nerve agents. Proc Natl Acad Sci U S A (2010) 1.20
Prevalence and risk factors of atherosclerosis in patients with psoriatic arthritis. Semin Arthritis Rheum (2006) 1.17
Stress-induced epigenetic transcriptional memory of acetylcholinesterase by HDAC4. Proc Natl Acad Sci U S A (2012) 1.16
Changes in brain MicroRNAs contribute to cholinergic stress reactions. J Mol Neurosci (2009) 1.16
Effects of Lactobacillus acidophilus NCFM on insulin sensitivity and the systemic inflammatory response in human subjects. Br J Nutr (2010) 1.16
Increased cerebral output of free radicals during hypoxia: implications for acute mountain sickness? Am J Physiol Regul Integr Comp Physiol (2009) 1.16
On the nature of burnout-insomnia relationships: a prospective study of employed adults. J Psychosom Res (2008) 1.16
Cholinergic status modulations in human volunteers under acute inflammation. J Mol Med (Berl) (2007) 1.15
Coagulopathy, catecholamines, and biomarkers of endothelial damage in experimental human endotoxemia and in patients with severe sepsis: a prospective study. J Crit Care (2013) 1.11
Short-term exposure to air pollution and inflammation-sensitive biomarkers. Environ Res (2007) 1.11
Platelet counts and platelet activation markers in obese subjects. Mediators Inflamm (2008) 1.10
Cerebrolysin in patients with acute ischemic stroke in Asia: results of a double-blind, placebo-controlled randomized trial. Stroke (2012) 1.09
Acetylcholinesterase/paraoxonase genotype and expression predict anxiety scores in Health, Risk Factors, Exercise Training, and Genetics study. Proc Natl Acad Sci U S A (2004) 1.09
Cholinergic-associated loss of hnRNP-A/B in Alzheimer's disease impairs cortical splicing and cognitive function in mice. EMBO Mol Med (2012) 1.09
The role of readthrough acetylcholinesterase in the pathophysiology of myasthenia gravis. FASEB J (2003) 1.08
Butyrylcholinesterase attenuates amyloid fibril formation in vitro. Proc Natl Acad Sci U S A (2006) 1.08
Termination and beyond: acetylcholinesterase as a modulator of synaptic transmission. Cell Tissue Res (2006) 1.07
Interaction of "readthrough" acetylcholinesterase with RACK1 and PKCbeta II correlates with intensified fear-induced conflict behavior. Proc Natl Acad Sci U S A (2002) 1.07
Revascularization of the right coronary artery in bilateral internal thoracic artery grafting. Ann Thorac Surg (2005) 1.06
Changes in readthrough acetylcholinesterase expression modulate amyloid-beta pathology. Brain (2007) 1.06
Acetylcholinesterase inhibitors reduce brain and blood interleukin-1beta production. Ann Neurol (2005) 1.05
Stroke: working toward a prioritized world agenda. Stroke (2010) 1.05
Transgenic plants as a source for the bioscavenging enzyme, human butyrylcholinesterase. Plant Biotechnol J (2010) 1.05
DP-b99, a membrane-activated metal ion chelator, as neuroprotective therapy in ischemic stroke. Stroke (2008) 1.04
Pre-mRNA splicing modulations in senescence. Aging Cell (2002) 1.03
Platelet inhibitory effect of clopidogrel in patients treated with omeprazole, pantoprazole, and famotidine: a prospective, randomized, crossover study. Clin Cardiol (2013) 1.02
Transcriptional regulation of erythropoiesis. Fine tuning of combinatorial multi-domain elements. Eur J Biochem (2002) 1.02
Environmental air pollution has decremental effects on pulmonary function test parameters up to one week after exposure. Am J Med Sci (2009) 1.01
Stroke: working toward a prioritized world agenda. Cerebrovasc Dis (2010) 1.01
Purification of transgenic plant-derived recombinant human acetylcholinesterase-R. Chem Biol Interact (2005) 0.98
Type 2 diabetes mellitus is associated with impaired cytokine response and adhesion molecule expression in human endotoxemia. Intensive Care Med (2010) 0.98
N-acetylcholinesterase-induced apoptosis in Alzheimer's disease. PLoS One (2008) 0.98
Burnout and risk of coronary heart disease: a prospective study of 8838 employees. Psychosom Med (2012) 0.97
CCSVI and MS: a statement from the European Society of neurosonology and cerebral hemodynamics. J Neurol (2012) 0.97
MicroRNA-132 modulates cholinergic signaling and inflammation in human inflammatory bowel disease. Inflamm Bowel Dis (2013) 0.97
Exon arrays reveal alternative splicing aberrations in Parkinson's disease leukocytes. Neurodegener Dis (2011) 0.96
Utility of lead aVR for identifying the culprit lesion in acute myocardial infarction. Ann Noninvasive Electrocardiol (2009) 0.96
Memory deficits correlating with acetylcholinesterase splice shift and amyloid burden in doubly transgenic mice. Curr Alzheimer Res (2005) 0.96
Blood-brain barrier dysfunction-induced inflammatory signaling in brain pathology and epileptogenesis. Epilepsia (2012) 0.95
Gene-environment interactions in sporadic Parkinson's disease. J Neurochem (2006) 0.95
Math1 target genes are enriched with evolutionarily conserved clustered E-box binding sites. J Mol Neurosci (2006) 0.95
Thrombophilic factors in idiopathic intracranial hypertension: a report of 51 patients and a meta-analysis. Blood Coagul Fibrinolysis (2010) 0.95
Small RNA sequencing-microarray analyses in Parkinson leukocytes reveal deep brain stimulation-induced splicing changes that classify brain region transcriptomes. Front Mol Neurosci (2013) 0.94
The butyrylcholinesterase K variant confers structurally derived risks for Alzheimer pathology. J Biol Chem (2009) 0.94
The interval between prothrombin time tests and the quality of oral anticoagulants treatment in patients with chronic atrial fibrillation. Thromb Res (2006) 0.93
Cholinesterases as biomarkers for parasympathetic dysfunction and inflammation-related disease. J Mol Neurosci (2013) 0.93
Acetylcholinesterase/paraoxonase interactions increase the risk of insecticide-induced Parkinson's disease. FASEB J (2005) 0.93