Published in J Biol Chem on April 28, 2004
Stress-induced epigenetic transcriptional memory of acetylcholinesterase by HDAC4. Proc Natl Acad Sci U S A (2012) 1.16
Alternative promoters influence alternative splicing at the genomic level. PLoS One (2008) 1.11
Altered levels of acetylcholinesterase in Alzheimer plasma. PLoS One (2010) 0.99
N-acetylcholinesterase-induced apoptosis in Alzheimer's disease. PLoS One (2008) 0.98
Revisiting the Role of Acetylcholinesterase in Alzheimer's Disease: Cross-Talk with P-tau and β-Amyloid. Front Mol Neurosci (2011) 0.97
High frequency of alternative first exons in erythroid genes suggests a critical role in regulating gene function. Blood (2005) 0.96
Acetylcholinesterase expression in muscle is specifically controlled by a promoter-selective enhancesome in the first intron. J Neurosci (2008) 0.93
Acetylcholinesterase loosens the brain's cholinergic anti-inflammatory response and promotes epileptogenesis. Front Mol Neurosci (2012) 0.88
Plant-derived human acetylcholinesterase-R provides protection from lethal organophosphate poisoning and its chronic aftermath. FASEB J (2007) 0.88
Transcriptional control of human antigen R by bone morphogenetic protein. J Biol Chem (2009) 0.87
Differential localization of acetylcholinesterase in neuronal and non-neuronal cells. J Cell Biochem (2005) 0.86
Identifying alternative hyper-splicing signatures in MG-thymoma by exon arrays. PLoS One (2008) 0.83
Trans-acting factors governing acetylcholinesterase mRNA metabolism in neurons. Front Mol Neurosci (2012) 0.83
Role of acetylcholinesterase in lung cancer. Thorac Cancer (2015) 0.83
Myocyte enhancer factor 2 activates promoter sequences of the human AbetaH-J-J locus, encoding aspartyl-beta-hydroxylase, junctin, and junctate. Mol Cell Biol (2005) 0.82
Translational control of recombinant human acetylcholinesterase accumulation in plants. BMC Biotechnol (2007) 0.82
Coupled transcription-splicing regulation of mutually exclusive splicing events at the 5' exons of protein 4.1R gene. Blood (2009) 0.81
Pro-apoptotic protein-protein interactions of the extended N-AChE terminus. J Neural Transm (Vienna) (2009) 0.80
Butyrylcholinesterase interactions with amylin may protect pancreatic cells in metabolic syndrome. J Cell Mol Med (2011) 0.80
Gut feeling: MicroRNA discriminators of the intestinal TLR9-cholinergic links. Int Immunopharmacol (2015) 0.77
Identification of a novel human LAP1 isoform that is regulated by protein phosphorylation. PLoS One (2014) 0.77
A novel role for synaptic acetylcholinesterase as an apoptotic deoxyribonuclease. Cell Discov (2015) 0.76
New treatments for myasthenia: a focus on antisense oligonucleotides. Drug Des Devel Ther (2013) 0.76
Neuromuscular Junction Impairment in Amyotrophic Lateral Sclerosis: Reassessing the Role of Acetylcholinesterase. Front Mol Neurosci (2016) 0.75
Different sensitivities of rat skeletal muscles and brain to novel anti-cholinesterase agents, alkylammonium derivatives of 6-methyluracil (ADEMS). Br J Pharmacol (2011) 0.75
Competitive regulation of alternative splicing and alternative polyadenylation by hnRNP H and CstF64 determines acetylcholinesterase isoforms. Nucleic Acids Res (2017) 0.75
Increased Expression of Readthrough Acetylcholinesterase Variants in the Brains of Alzheimer's Disease Patients. J Alzheimers Dis (2016) 0.75
It all starts at the ends: multifaceted involvement of C- and N-terminally modified cholinesterases in Alzheimer's disease. Rambam Maimonides Med J (2010) 0.75
Bovine Herpes Virus 1 Major Immediate Early Transcription Unit 1 (IETU-1) Uses Alternative Promoters to Transcribe BICP0 and BICP4 Transcripts. Curr Microbiol (2015) 0.75
Function of alternative splicing. Gene (2004) 5.95
The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha. Cell (2010) 5.11
IL-1 is required for tumor invasiveness and angiogenesis. Proc Natl Acad Sci U S A (2003) 3.80
Disruption of CREB function in brain leads to neurodegeneration. Nat Genet (2002) 3.54
The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism. Cell (2012) 2.78
Identifying subtle interrelated changes in functional gene categories using continuous measures of gene expression. Bioinformatics (2004) 2.47
Acute generalized exanthematous pustulosis following a spider bite: report of 3 cases. J Am Acad Dermatol (2006) 2.38
Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9. Gastroenterology (2009) 2.33
MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase. Immunity (2009) 2.33
Bile system morphogenesis defects and liver dysfunction upon targeted deletion of HNF1beta. Development (2002) 2.27
A novel founder mutation in the RNASEL gene, 471delAAAG, is associated with prostate cancer in Ashkenazi Jews. Am J Hum Genet (2002) 2.24
Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver. EMBO J (2002) 2.15
Differential localization of LGR5 and Nanog in clusters of colon cancer stem cells. Acta Histochem (2012) 1.99
Liver adenosine monophosphate-activated kinase-alpha2 catalytic subunit is a key target for the control of hepatic glucose production by adiponectin and leptin but not insulin. Endocrinology (2006) 1.81
Chronic stress triggers social aversion via glucocorticoid receptor in dopaminoceptive neurons. Science (2013) 1.76
The MAPK pathway and Egr-1 mediate stress-related behavioral effects of glucocorticoids. Nat Neurosci (2005) 1.66
Normal and abnormal 18F-FDG endometrial and ovarian uptake in pre- and postmenopausal patients: assessment by PET/CT. J Nucl Med (2004) 1.64
RACK1 has the nerve to act: structure meets function in the nervous system. Prog Neurobiol (2006) 1.56
Combined weekly carboplatin and paclitaxel as primary treatment of advanced epithelial ovarian carcinoma. Gynecol Oncol (2009) 1.56
A SIRT1-LSD1 corepressor complex regulates Notch target gene expression and development. Mol Cell (2011) 1.55
Alteration of the microRNA network during the progression of Alzheimer's disease. EMBO Mol Med (2013) 1.54
Macrophages and neutrophils are the targets for immune suppression by glucocorticoids in contact allergy. J Clin Invest (2007) 1.51
Stress and addiction: glucocorticoid receptor in dopaminoceptive neurons facilitates cocaine seeking. Nat Neurosci (2009) 1.51
Chronic cholinergic imbalances promote brain diffusion and transport abnormalities. FASEB J (2005) 1.50
A network-based method for predicting disease-causing genes. J Comput Biol (2009) 1.49
MicroRNA modulation of megakaryoblast fate involves cholinergic signaling. Leuk Res (2005) 1.49
Sertoli cell maturation in men with azoospermia of different etiologies. Fertil Steril (2002) 1.46
Virtues and woes of AChE alternative splicing in stress-related neuropathologies. Trends Neurosci (2006) 1.45
Significance of residual tumor cells after re-excision of incompletely excised basal cell carcinomas. Plast Reconstr Surg (2002) 1.44
Hepatocyte proliferation during liver regeneration is impaired in mice with liver-specific IGF-1R knockout. FASEB J (2006) 1.39
Alternative splicing and neuritic mRNA translocation under long-term neuronal hypersensitivity. Science (2002) 1.39
The glucocorticoid receptor as a potential target to reduce cocaine abuse. J Neurosci (2003) 1.34
Stabilization of beta-catenin affects mouse embryonic liver growth and hepatoblast fate. Hepatology (2008) 1.31
Conditional inactivation of androgen receptor gene in the nervous system: effects on male behavioral and neuroendocrine responses. J Neurosci (2009) 1.29
Defects in pre-mRNA processing as causes of and predisposition to diseases. DNA Cell Biol (2002) 1.28
Comparison of adnexal torsion between pregnant and nonpregnant women. Am J Obstet Gynecol (2010) 1.26
Deletion of murine Smn exon 7 directed to liver leads to severe defect of liver development associated with iron overload. Am J Pathol (2004) 1.24
Heterogeneous nuclear ribonucleoprotein G regulates splice site selection by binding to CC(A/C)-rich regions in pre-mRNA. J Biol Chem (2009) 1.23
Deficiency of PDK1 in liver results in glucose intolerance, impairment of insulin-regulated gene expression and liver failure. Biochem J (2005) 1.23
Inactivation of the glucocorticoid receptor in hepatocytes leads to fasting hypoglycemia and ameliorates hyperglycemia in streptozotocin-induced diabetes mellitus. Mol Endocrinol (2004) 1.21
Plant-derived human butyrylcholinesterase, but not an organophosphorous-compound hydrolyzing variant thereof, protects rodents against nerve agents. Proc Natl Acad Sci U S A (2010) 1.20
Expression of Cre recombinase in dopaminoceptive neurons. BMC Neurosci (2007) 1.19
Stress-induced epigenetic transcriptional memory of acetylcholinesterase by HDAC4. Proc Natl Acad Sci U S A (2012) 1.16
Changes in brain MicroRNAs contribute to cholinergic stress reactions. J Mol Neurosci (2009) 1.16
Analysis of dopamine transporter gene expression pattern -- generation of DAT-iCre transgenic mice. FEBS J (2007) 1.16
Cholinergic status modulations in human volunteers under acute inflammation. J Mol Med (Berl) (2007) 1.15
When reverse genetics meets physiology: the use of site-specific recombinases in mice. FEBS Lett (2002) 1.13
Sirt1 is a regulator of bone mass and a repressor of Sost encoding for sclerostin, a bone formation inhibitor. Endocrinology (2011) 1.11
Dissecting the role of glucocorticoids on pancreas development. Diabetes (2004) 1.09
Acetylcholinesterase/paraoxonase genotype and expression predict anxiety scores in Health, Risk Factors, Exercise Training, and Genetics study. Proc Natl Acad Sci U S A (2004) 1.09
Cholinergic-associated loss of hnRNP-A/B in Alzheimer's disease impairs cortical splicing and cognitive function in mice. EMBO Mol Med (2012) 1.09
The role of readthrough acetylcholinesterase in the pathophysiology of myasthenia gravis. FASEB J (2003) 1.08
Differential effects of IL-1 alpha and IL-1 beta on tumorigenicity patterns and invasiveness. J Immunol (2003) 1.08
Butyrylcholinesterase attenuates amyloid fibril formation in vitro. Proc Natl Acad Sci U S A (2006) 1.08
Termination and beyond: acetylcholinesterase as a modulator of synaptic transmission. Cell Tissue Res (2006) 1.07
Interaction of "readthrough" acetylcholinesterase with RACK1 and PKCbeta II correlates with intensified fear-induced conflict behavior. Proc Natl Acad Sci U S A (2002) 1.07
Microglial glucocorticoid receptors play a pivotal role in regulating dopaminergic neurodegeneration in parkinsonism. Proc Natl Acad Sci U S A (2011) 1.07
Changes in readthrough acetylcholinesterase expression modulate amyloid-beta pathology. Brain (2007) 1.06
Acetylcholinesterase inhibitors reduce brain and blood interleukin-1beta production. Ann Neurol (2005) 1.05
Transgenic plants as a source for the bioscavenging enzyme, human butyrylcholinesterase. Plant Biotechnol J (2010) 1.05
Gene transfer and genetic modification of embryonic stem cells by Cre- and Cre-PR-expressing MESV-based retroviral vectors. J Gene Med (2004) 1.04
Serum cholinesterase activities distinguish between stroke patients and controls and predict 12-month mortality. Mol Med (2010) 1.04
Pre-mRNA splicing modulations in senescence. Aging Cell (2002) 1.03
Transcriptional regulation of erythropoiesis. Fine tuning of combinatorial multi-domain elements. Eur J Biochem (2002) 1.02
Corticosteroid receptors in the brain: gene targeting studies. Brain Res Bull (2002) 0.99
Purification of transgenic plant-derived recombinant human acetylcholinesterase-R. Chem Biol Interact (2005) 0.98
N-acetylcholinesterase-induced apoptosis in Alzheimer's disease. PLoS One (2008) 0.98
MicroRNA-132 modulates cholinergic signaling and inflammation in human inflammatory bowel disease. Inflamm Bowel Dis (2013) 0.97
Exon arrays reveal alternative splicing aberrations in Parkinson's disease leukocytes. Neurodegener Dis (2011) 0.96
Distribution of the zinc transporter ZnT-1 in comparison with chelatable zinc in the mouse brain. J Comp Neurol (2002) 0.96
Memory deficits correlating with acetylcholinesterase splice shift and amyloid burden in doubly transgenic mice. Curr Alzheimer Res (2005) 0.96
Conditional glucocorticoid receptor expression in the heart induces atrio-ventricular block. FASEB J (2007) 0.95
Gene-environment interactions in sporadic Parkinson's disease. J Neurochem (2006) 0.95
Blood-brain barrier dysfunction-induced inflammatory signaling in brain pathology and epileptogenesis. Epilepsia (2012) 0.95
Inactivation of the GR in the nervous system affects energy accumulation. Endocrinology (2002) 0.95
Small RNA sequencing-microarray analyses in Parkinson leukocytes reveal deep brain stimulation-induced splicing changes that classify brain region transcriptomes. Front Mol Neurosci (2013) 0.94
The butyrylcholinesterase K variant confers structurally derived risks for Alzheimer pathology. J Biol Chem (2009) 0.94
Sarcoidosis presenting as "corset-like" myelopathy: a description of six cases and literature review. Clin Rev Allergy Immunol (2010) 0.94
Members of the CDY family have different expression patterns: CDY1 transcripts have the best correlation with complete spermatogenesis. Hum Genet (2003) 0.94
The neural androgen receptor: a therapeutic target for myelin repair in chronic demyelination. Brain (2013) 0.93
Cholinesterases as biomarkers for parasympathetic dysfunction and inflammation-related disease. J Mol Neurosci (2013) 0.93
Hydrolytic and nonenzymatic functions of acetylcholinesterase comodulate hemopoietic stress responses. J Immunol (2006) 0.93
Acetylcholinesterase/paraoxonase interactions increase the risk of insecticide-induced Parkinson's disease. FASEB J (2005) 0.93
Global coevolution of human microRNAs and their target genes. Mol Biol Evol (2014) 0.93
Advanced microarray analysis highlights modified neuro-immune signaling in nucleated blood cells from Parkinson's disease patients. J Neuroimmunol (2008) 0.92
Risk factors for incomplete excision of basal cell carcinomas. Acta Derm Venereol (2004) 0.92
The stress-associated acetylcholinesterase variant AChE-R is expressed in human CD34(+) hematopoietic progenitors and its C-terminal peptide ARP promotes their proliferation. Exp Hematol (2002) 0.91
Erythropoietin attenuates hyperoxia-induced oxidative stress in the developing rat brain. Brain Behav Immun (2009) 0.91
Adaptive changes in acetylcholinesterase gene expression as mediators of recovery from chemical and biological insults. Toxicology (2006) 0.91
Cholinesterase-Targeting microRNAs Identified in silico Affect Specific Biological Processes. Front Mol Neurosci (2011) 0.90
Plasticity of hypothalamic dopamine neurons during lactation results in dissociation of electrical activity and release. J Neurosci (2013) 0.90
Stressing hematopoiesis and immunity: an acetylcholinesterase window into nervous and immune system interactions. Front Mol Neurosci (2012) 0.90
Heterogeneous nuclear ribonucleoprotein A1 in health and neurodegenerative disease: from structural insights to post-transcriptional regulatory roles. Mol Cell Neurosci (2012) 0.90
Endotoxin-induced changes in human working and declarative memory associate with cleavage of plasma "readthrough" acetylcholinesterase. J Mol Neurosci (2003) 0.89
RNA-targeted suppression of stress-induced allostasis in primate spinal cord neurons. Neurodegener Dis (2005) 0.89
Activation of the alternative NFκB pathway improves disease symptoms in a model of Sjogren's syndrome. PLoS One (2011) 0.89
Fetal PGC-1α overexpression programs adult pancreatic β-cell dysfunction. Diabetes (2012) 0.89
A versatile system for the neuronal subtype specific expression of lentiviral vectors. FASEB J (2009) 0.89