Published in Mar Drugs on April 23, 2010
Three bianthraquinone derivatives from the mangrove endophytic fungus Alternaria sp. ZJ9-6B from the South China Sea. Mar Drugs (2011) 1.06
Nutrition and bioprocess development for efficient biosynthesis of an antitumor compound from marine-derived fungus. J Ind Microbiol Biotechnol (2013) 0.90
Cellular antioxidative, cytotoxic, and antileishmanial activities of Homalium letestui. Avicenna J Phytomed (2013) 0.79
Advances in the study of the structures and bioactivities of metabolites isolated from mangrove-derived fungi in the South China Sea. Mar Drugs (2013) 0.79
Characterization of cytotoxic compound from mangrove derived fungi Irpex hydnoides VB4. Asian Pac J Trop Biomed (2011) 0.78
Bruceine D induces apoptosis in human chronic myeloid leukemia K562 cells via mitochondrial pathway. Am J Cancer Res (2016) 0.78
Endophytic fungi: expanding the arsenal of industrial enzyme producers. J Ind Microbiol Biotechnol (2014) 0.77
Evaluation of Rumex hastatus D. Don for cytotoxic potential against HeLa and NIH/3T3 cell lines: chemical characterization of chloroform fraction and identification of bioactive compounds. BMC Complement Altern Med (2016) 0.76
Antitumor activity of bacterial exopolysaccharides from the endophyte Bacillus amyloliquefaciens sp. isolated from Ophiopogon japonicus. Oncol Lett (2013) 0.76
Biological Evaluation of Endophytic Fungus Chaetomium sp. NF15 of Justicia adhatoda L.: A Potential Candidate for Drug Discovery. Jundishapur J Microbiol (2016) 0.75
Anthraquinones and Derivatives from Marine-Derived Fungi: Structural Diversity and Selected Biological Activities. Mar Drugs (2016) 0.75
Streptomyces artemisiae MCCB 248 isolated from Arctic fjord sediments has unique PKS and NRPS biosynthetic genes and produces potential new anticancer natural products. 3 Biotech (2017) 0.75
Drug development from marine natural products. Nat Rev Drug Discov (2008) 4.08
Marine natural products as anticancer drugs. Mol Cancer Ther (2005) 2.93
Drug Discovery, CAM and Natural Products. Evid Based Complement Alternat Med (2004) 2.64
Natural products as leads to anticancer drugs. Clin Transl Oncol (2007) 2.31
Erlotinib (Tarceva, OSI-774) antagonizes ATP-binding cassette subfamily B member 1 and ATP-binding cassette subfamily G member 2-mediated drug resistance. Cancer Res (2007) 2.15
Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2. Cancer Res (2008) 2.04
The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis. Proc Natl Acad Sci U S A (1998) 1.60
Antitumor compounds from marine actinomycetes. Mar Drugs (2009) 1.44
The role of mitochondria in health and disease. Curr Opin Pharmacol (2009) 1.37
Lgf-YL-9 induces apoptosis in human epidermoid carcinoma KB cells and multidrug resistant KBv200 cells via reactive oxygen species-independent mitochondrial pathway. Cancer Lett (2006) 1.22
Anthracenedione derivative 1403P-3 induces apoptosis in KB and KBv200 cells via reactive oxygen species-independent mitochondrial pathway and death receptor pathway. Cancer Biol Ther (2007) 1.14
The anthracycline antibiotics: antitumor drugs that alter chromatin structure. Bioessays (2005) 1.12
Evaluation of aloin and aloe-emodin as anti-inflammatory agents in aloe by using murine macrophages. Biosci Biotechnol Biochem (2009) 1.11
Bax contains two functional mitochondrial targeting sequences and translocates to mitochondria in a conformational change- and homo-oligomerization-driven process. J Biol Chem (2009) 1.10
Secalonic acid D induced leukemia cell apoptosis and cell cycle arrest of G(1) with involvement of GSK-3beta/beta-catenin/c-Myc pathway. Cell Cycle (2009) 1.07
Anthracycline- and/or taxane-resistant breast cancer: results of a literature review to determine the clinical challenges and current treatment trends. Clin Ther (2009) 1.03
Aloe-emodin induces cell death through S-phase arrest and caspase-dependent pathways in human tongue squamous cancer SCC-4 cells. Anticancer Res (2009) 1.02
Emodin azide methyl anthraquinone derivative triggers mitochondrial-dependent cell apoptosis involving in caspase-8-mediated Bid cleavage. Mol Cancer Ther (2008) 1.00
(1)H and (13)C NMR assignments for five anthraquinones from the mangrove endophytic fungus Halorosellinia sp. (No. 1403). Magn Reson Chem (2007) 1.00
P-glycoprotein inhibits caspase-8 activation but not formation of the death inducing signal complex (disc) following Fas ligation. Cell Death Differ (2002) 0.97
Natural anthraquinone derivatives from a marine mangrove plant-derived endophytic fungus Eurotium rubrum: structural elucidation and DPPH radical scavenging activity. J Microbiol Biotechnol (2009) 0.96
Discovering novel quercetin-3-O-amino acid-esters as a new class of Src tyrosine kinase inhibitors. Eur J Med Chem (2008) 0.89
Amide bond direction modulates G-quadruplex recognition and telomerase inhibition by 2,6 and 2,7 bis-substituted anthracenedione derivatives. Bioorg Med Chem (2007) 0.86
New drugs from the sea. J Chemother (2004) 0.84
Marine-derived metabolites of S-adenosylmethionine as templates for new anti-infectives. Mar Drugs (2009) 0.83
Inhibition of HIV-1 ribonuclease H activity by novel frangula-emodine derivatives. Med Chem (2009) 0.82
AQ4, an antitumor anthracenedione, inhibits endothelial cell proliferation and vascular endothelial growth factor secretion: implications for the therapy of ocular neovascular disorders. Eur J Pharmacol (2007) 0.81
Chromosomal aberration and micronucleus studies of two topoisomerase (II) targeting anthracyclines. J Environ Biol (2009) 0.81
The role of mitochondrial dysfunction and drug safety. IDrugs (2009) 0.79
Biotechnology and biochemistry of marine natural products. P R Health Sci J (2009) 0.78
Prevalence of chronic kidney disease in China: a cross-sectional survey. Lancet (2012) 10.53
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells. Science (2013) 5.10
Plasma soluble urokinase receptor levels are increased but do not distinguish primary from secondary focal segmental glomerulosclerosis. Kidney Int (2013) 3.97
Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation. Proc Natl Acad Sci U S A (2005) 3.16
Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth. Proc Natl Acad Sci U S A (2011) 3.14
Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humans. Hepatology (2011) 3.05
Human microRNA clusters: genomic organization and expression profile in leukemia cell lines. Biochem Biophys Res Commun (2006) 2.65
Repression of the long noncoding RNA-LET by histone deacetylase 3 contributes to hypoxia-mediated metastasis. Mol Cell (2013) 2.61
SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1. J Biol Chem (2005) 2.59
Alterations in the common fragile site gene Parkin in ovarian and other cancers. Oncogene (2003) 2.44
The human serum proteome: display of nearly 3700 chromatographically separated protein spots on two-dimensional electrophoresis gels and identification of 325 distinct proteins. Proteomics (2003) 2.41
Chemical and toxicological investigations of a previously unknown poisonous European mushroom Tricholoma terreum. Chemistry (2014) 2.27
Prevalence and factors associated with CKD: a population study from Beijing. Am J Kidney Dis (2008) 2.09
Common genetic variants of the human uromodulin gene regulate transcription and predict plasma uric acid levels. Kidney Int (2013) 2.05
Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2. Cancer Res (2008) 2.04
Lactate dehydrogenase B is critical for hyperactive mTOR-mediated tumorigenesis. Cancer Res (2011) 2.00
Dietary and lifestyle changes associated with high prevalence of hyperuricemia and gout in the Shandong coastal cities of Eastern China. J Rheumatol (2008) 2.00
Hormonal control of androgen receptor function through SIRT1. Mol Cell Biol (2006) 1.91
Location matters: site of conjugation modulates stability and pharmacokinetics of antibody drug conjugates. Chem Biol (2013) 1.82
Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade. J Clin Invest (2009) 1.80
Octamer 4 small interfering RNA results in cancer stem cell-like cell apoptosis. Cancer Res (2008) 1.76
MicroRNA-29a and microRNA-142-3p are regulators of myeloid differentiation and acute myeloid leukemia. Blood (2012) 1.75
Reversal of MDR1/P-glycoprotein-mediated multidrug resistance by vector-based RNA interference in vitro and in vivo. Cancer Biol Ther (2006) 1.73
Arabidopsis homolog of the yeast TREX-2 mRNA export complex: components and anchoring nucleoporin. Plant J (2009) 1.73
Epigenetic activation of the MiR-200 family contributes to H19-mediated metastasis suppression in hepatocellular carcinoma. Carcinogenesis (2012) 1.65
Physiological and transcriptome analysis of iron and phosphorus interaction in rice seedlings. Plant Physiol (2009) 1.65
Relation between hypomethylation of long interspersed nucleotide elements and risk of neural tube defects. Am J Clin Nutr (2010) 1.63
Dynamical quorum sensing and synchronization in large populations of chemical oscillators. Science (2009) 1.60
Regulation of the cell cycle gene, BTG2, by miR-21 in human laryngeal carcinoma. Cell Res (2009) 1.58
Estrogen-related receptors stimulate pyruvate dehydrogenase kinase isoform 4 gene expression. J Biol Chem (2006) 1.56
DNA methylation downregulated mir-10b acts as a tumor suppressor in gastric cancer. Gastric Cancer (2014) 1.56
Apatinib (YN968D1) reverses multidrug resistance by inhibiting the efflux function of multiple ATP-binding cassette transporters. Cancer Res (2010) 1.55
Implication of genetic variants near SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, FTO, TCF2, KCNQ1, and WFS1 in type 2 diabetes in a Chinese population. BMC Med Genet (2010) 1.54
Initial neutrophil lymphocyte ratio is superior to platelet lymphocyte ratio as an adverse prognostic and predictive factor in metastatic colorectal cancer. Med Oncol (2013) 1.52
PVD following plasmin but not hyaluronidase: implications for combination pharmacologic vitreolysis therapy. Retina (2005) 1.52
Peptide YY3-36 and glucagon-like peptide-17-36 inhibit food intake additively. Endocrinology (2005) 1.49
Soybean NAC transcription factors promote abiotic stress tolerance and lateral root formation in transgenic plants. Plant J (2011) 1.48
Overprescribing in China, driven by financial incentives, results in very high use of antibiotics, injections, and corticosteroids. Health Aff (Millwood) (2012) 1.48
Sphingosine kinase type 1 induces G12/13-mediated stress fiber formation, yet promotes growth and survival independent of G protein-coupled receptors. J Biol Chem (2003) 1.47
Heat shock protein 70 silencing enhances apoptosis inducing factor-mediated cell death in hepatocellular carcinoma HepG2 cells. Cancer Biol Ther (2009) 1.44
Jasmonate regulates the inducer of cbf expression-C-repeat binding factor/DRE binding factor1 cascade and freezing tolerance in Arabidopsis. Plant Cell (2013) 1.43
Fluorescent chemosensors based on spiroring-opening of xanthenes and related derivatives. Chem Rev (2011) 1.40
Long noncoding RNAs associated with liver regeneration 1 accelerates hepatocyte proliferation during liver regeneration by activating Wnt/β-catenin signaling. Hepatology (2013) 1.40
Does obesity attenuate the effect of metabolic syndrome on chronic kidney disease in patients with coronary artery disease? Report from China heart survey. Circ J (2010) 1.40
Capsule structural heterogeneity and antigenic variation in Cryptococcus neoformans. Eukaryot Cell (2007) 1.39
Tumor-infiltrating γδ T lymphocytes predict clinical outcome in human breast cancer. J Immunol (2012) 1.38
QDMR: a quantitative method for identification of differentially methylated regions by entropy. Nucleic Acids Res (2011) 1.37
Identification and expansion of cancer stem cells in tumor tissues and peripheral blood derived from gastric adenocarcinoma patients. Cell Res (2011) 1.36
Protection by tetrahydroxystilbene glucoside against cerebral ischemia: involvement of JNK, SIRT1, and NF-kappaB pathways and inhibition of intracellular ROS/RNS generation. Free Radic Biol Med (2009) 1.34
Mutation in nicotianamine aminotransferase stimulated the Fe(II) acquisition system and led to iron accumulation in rice. Plant Physiol (2007) 1.34
Analysis of inpatient bed allocation equity and utilization in the city community health service center of China. J Huazhong Univ Sci Technolog Med Sci (2010) 1.34
Community-based screening for chronic kidney disease among populations older than 40 years in Beijing. Nephrol Dial Transplant (2007) 1.32
miR-17-5p Promotes migration of human hepatocellular carcinoma cells through the p38 mitogen-activated protein kinase-heat shock protein 27 pathway. Hepatology (2010) 1.31
Biodiesel production with immobilized lipase: A review. Biotechnol Adv (2010) 1.28
HHMD: the human histone modification database. Nucleic Acids Res (2009) 1.27
Plexin-B1 is a target of miR-214 in cervical cancer and promotes the growth and invasion of HeLa cells. Int J Biochem Cell Biol (2011) 1.27
Arabidopsis transcription factor WRKY8 functions antagonistically with its interacting partner VQ9 to modulate salinity stress tolerance. Plant J (2013) 1.26
Hollow porous SiO2 nanocubes towards high-performance anodes for lithium-ion batteries. Sci Rep (2013) 1.26
Disruption of palladin results in neural tube closure defects in mice. Mol Cell Neurosci (2005) 1.26
A novel receptor function for the heat shock protein Grp78: silencing of Grp78 gene expression attenuates alpha2M*-induced signalling. Cell Signal (2004) 1.26
High tumor-infiltrating macrophage density predicts poor prognosis in patients with primary hepatocellular carcinoma after resection. Hum Pathol (2008) 1.26
Utility of mycobacterial interspersed repetitive unit typing for differentiating Mycobacterium tuberculosis isolates in Wuhan, China. J Med Microbiol (2007) 1.25
Changes in soil properties after establishment of Artemisia halodendron and Caragana microphylla on shifting sand dunes in semiarid Horqin Sandy Land, northern China. Environ Manage (2005) 1.24
Sensitization of ABCG2-overexpressing cells to conventional chemotherapeutic agent by sunitinib was associated with inhibiting the function of ABCG2. Cancer Lett (2009) 1.24
Induction of oxidative and nitrosative damage leads to cerebrovascular inflammation in an animal model of mild traumatic brain injury induced by primary blast. Free Radic Biol Med (2013) 1.23
Characterization of healing following atherosclerotic carotid plaque rupture in acutely symptomatic patients: an exploratory study using in vivo cardiovascular magnetic resonance. J Cardiovasc Magn Reson (2011) 1.22
Association of telomere length with authentic pluripotency of ES/iPS cells. Cell Res (2011) 1.22
Analysis of tubulin isotypes and mutations from taxol-resistant cells by combined isoelectrofocusing and mass spectrometry. Biochemistry (2003) 1.22
DiseaseMeth: a human disease methylation database. Nucleic Acids Res (2011) 1.22
Bioproducts from Aureobasidium pullulans, a biotechnologically important yeast. Appl Microbiol Biotechnol (2009) 1.22
Fluorescence turn on of coumarin derivatives by metal cations: a new signaling mechanism based on C=N isomerization. Org Lett (2007) 1.22
Opaque1 encodes a myosin XI motor protein that is required for endoplasmic reticulum motility and protein body formation in maize endosperm. Plant Cell (2012) 1.21
DFT studies on a high energy density cage compound 4-trinitroethyl-2,6,8,10,12-pentanitrohezaazaisowurtzitane. J Phys Chem A (2011) 1.21
The Tumor Suppressor Roles of miR-433 and miR-127 in Gastric Cancer. Int J Mol Sci (2013) 1.21
Cardiotoxic and cardioprotective features of chronic β-adrenergic signaling. Circ Res (2012) 1.20
Blockage of JAK/STAT signalling attenuates renal ischaemia-reperfusion injury in rat. Nephrol Dial Transplant (2007) 1.20
Piglets cloned from induced pluripotent stem cells. Cell Res (2012) 1.19
Risk factors of diabetic retinopathy in type 2 diabetic patients. Chin Med J (Engl) (2006) 1.18
Expression of nodal signalling components in cycling human endometrium and in endometrial cancer. Reprod Biol Endocrinol (2009) 1.18
MicroRNAs are involved in erythroid differentiation control. J Cell Biochem (2009) 1.18
Melittin prevents liver cancer cell metastasis through inhibition of the Rac1-dependent pathway. Hepatology (2008) 1.17
The histone deacetylase 4/SP1/microrna-200a regulatory network contributes to aberrant histone acetylation in hepatocellular carcinoma. Hepatology (2011) 1.17
Modulation of the unfolded protein response is the core of microRNA-122-involved sensitivity to chemotherapy in hepatocellular carcinoma. Neoplasia (2011) 1.16
miR-20a promotes migration and invasion by regulating TNKS2 in human cervical cancer cells. FEBS Lett (2012) 1.16
MicroRNA-200b regulates cyclin D1 expression and promotes S-phase entry by targeting RND3 in HeLa cells. Mol Cell Biochem (2010) 1.15
Snail involves in the transforming growth factor β1-mediated epithelial-mesenchymal transition of retinal pigment epithelial cells. PLoS One (2011) 1.14
Anthracenedione derivative 1403P-3 induces apoptosis in KB and KBv200 cells via reactive oxygen species-independent mitochondrial pathway and death receptor pathway. Cancer Biol Ther (2007) 1.14
Reversal of P-gp mediated multidrug resistance in-vitro and in-vivo by FG020318. J Pharm Pharmacol (2004) 1.14