Apatinib (YN968D1) reverses multidrug resistance by inhibiting the efflux function of multiple ATP-binding cassette transporters.

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Published in Cancer Res on September 28, 2010

Authors

Yan-Jun Mi1, Yong-Ju Liang, Hong-Bing Huang, Hong-Yun Zhao, Chung-Pu Wu, Fang Wang, Li-Yang Tao, Chuan-Zhao Zhang, Chun-Ling Dai, Amit K Tiwari, Xiao-Xu Ma, Kenneth Kin Wah To, Suresh V Ambudkar, Zhe-Sheng Chen, Li-Wu Fu

Author Affiliations

1: State Key Laboratory of Oncology in South China, Cancer Center, Sun Yat-Sen University, Guangzhou, China.

Associated clinical trials:

Apatinib in Advanced Non-squamous,NSCLC | NCT03376191

Efficacy and Safety of Apatinib as Third-line Therapy for Primary Pulmonary Lymphoepithelioid Carcinoma (Spark-AL003) | NCT03709953

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