W R Pearson

Author PubWeight™ 152.19‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Rapid and sensitive protein similarity searches. Science 1985 76.83
2 Aligning two sequences within a specified diagonal band. Comput Appl Biosci 1992 19.31
3 Rapid and sensitive sequence comparison with FASTP and FASTA. Methods Enzymol 1990 17.64
4 Hereditary differences in the expression of the human glutathione transferase active on trans-stilbene oxide are due to a gene deletion. Proc Natl Acad Sci U S A 1988 3.75
5 A program for least squares analysis of reassociation and hybridization data. Nucleic Acids Res 1977 3.13
6 Nomenclature for human glutathione transferases. Biochem J 1992 2.71
7 Automatic construction of restriction site maps. Nucleic Acids Res 1982 1.92
8 Empirical determination of effective gap penalties for sequence comparison. Bioinformatics 2002 1.78
9 Increased synthesis of glutathione S-transferases in response to anticarcinogenic antioxidants. Cloning and measurement of messenger RNA. J Biol Chem 1983 1.68
10 Evolution of protein sequences and structures. J Mol Biol 1999 1.65
11 Cloning, expression, and characterization of a class-mu glutathione transferase from human muscle, the product of the GST4 locus. Proc Natl Acad Sci U S A 1991 1.46
12 The origin of nuclear receptor proteins: a single precursor distinct from other transcription factors. Mol Endocrinol 1992 1.21
13 Regulation of synthesis of amyloid A-related protein. Ann N Y Acad Sci 1982 1.20
14 Heterologous expression of the allelic variant mu-class glutathione transferases mu and psi. Biochem J 1991 1.18
15 A platform for biological sequence comparison on parallel computers. Comput Appl Biosci 1991 1.16
16 Analysis of rat repetitive DNA sequences. Biochemistry 1978 1.16
17 Absence of short period interspersion of repetitive and non-repetitive sequences in the DNA of Drosophila melanogaster. Chromosoma 1976 1.14
18 Characterization of the human class Mu glutathione S-transferase gene cluster and the GSTM1 deletion. J Biol Chem 1998 1.11
19 Repeated DNA sequences near the 5'-end of the silk fibroin gene. J Biol Chem 1981 1.10
20 Use of site-directed mutagenesis of allele-specific PCR primers to identify the GSTM1 A, GSTM1 B, GSTM1 A,B and GSTM1 null polymorphisms at the glutathione S-transferase, GSTM1 locus. Biochem J 1993 1.08
21 Stoichiometry of chromatin proteins. Biochem Biophys Res Commun 1974 1.06
22 Molecular characterization of alpha 1- and alpha 2-adrenoceptors. Trends Pharmacol Sci 1991 1.02
23 Training for bioinformatics and computational biology. Bioinformatics 2001 0.96
24 The structure of two murine class-mu glutathione transferase genes coordinately induced by butylated hydroxyanisole. Arch Biochem Biophys 1993 0.96
25 Long and short repeats of sea urchin DNA and their evolution. Chromosoma 1981 0.93
26 Rapid identification of protein phosphatase 1-binding proteins by mixed peptide sequencing and data base searching. Characterization of a novel holoenzymic form of protein phosphatase 1. J Biol Chem 1998 0.90
27 Sequence relationship between long and short repetitive DNA of the rat: a preliminary report. Proc Natl Acad Sci U S A 1977 0.87
28 Aligning a DNA sequence with a protein sequence. J Comput Biol 1997 0.86
29 Homozygous deletion of gene for glutathione S-transferase M1 in bladder cancer. BMJ 1993 0.85
30 Computer programs for analysis of nucleic acid hybridization, thermal denaturation, and gel electrophoresis data. Nucleic Acids Res 1979 0.82
31 Discrete-length repeated sequences in eukaryotic genomes. Proc Natl Acad Sci U S A 1981 0.81
32 Differences in induction by xenobiotics in murine tissues and the Hepa1c1c7 cell line of mRNAs encoding glutathione transferase, quinone reductase, and CYP1A P450s. Pharmacogenetics 1993 0.81
33 Sequence organization of the rat genome by electron microscopy. Biochemistry 1978 0.80
34 Panning for genes--A visual strategy for identifying novel gene orthologs and paralogs. Genome Res 1999 0.80
35 Distinctive structure of the human GSTM3 gene-inverted orientation relative to the mu class glutathione transferase gene cluster. Arch Biochem Biophys 1999 0.77
36 Comparing machine-independent versus machine-specific parallelization of a software platform for biological sequence comparison. Comput Appl Biosci 1992 0.75
37 Primary structure of avian H+/K(+)-ATPase beta-subunit. Biochim Biophys Acta 1994 0.75
38 Programming languages. II. MD Comput 1987 0.75
39 Tracking the stock market. MD Comput 1984 0.75
40 Programming languages III. MD Comput 1986 0.75