Published in Biochem J on June 01, 1991
Detoxication of base propenals and other alpha, beta-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferases. Proc Natl Acad Sci U S A (1994) 2.02
Identification of class-mu glutathione transferase genes GSTM1-GSTM5 on human chromosome 1p13. Am J Hum Genet (1993) 1.83
Isothiocyanates as substrates for human glutathione transferases: structure-activity studies. Biochem J (1995) 1.67
Participation of the phenolic hydroxyl group of Tyr-8 in the catalytic mechanism of human glutathione transferase P1-1. Biochem J (1992) 1.23
Cloning and heterologous expression of cDNA encoding class alpha rat glutathione transferase 8-8, an enzyme with high catalytic activity towards genotoxic alpha,beta-unsaturated carbonyl compounds. Biochem J (1992) 1.08
Perspectives on the chemical etiology of breast cancer. Environ Health Perspect (2002) 1.06
Genotyping for polymorphisms in xenobiotic metabolism as a predictor of disease susceptibility. Environ Health Perspect (1994) 1.02
Deduced amino acid sequence, gene structure and chromosomal location of a novel human class Mu glutathione S-transferase, GSTM4. Biochem J (1993) 0.99
Meta-analysis and pooled analysis of GSTM1 and CYP1A1 polymorphisms and oral and pharyngeal cancers: a HuGE-GSEC review. Genet Med (2008) 0.97
Population-specific GSTM1 copy number variation. Hum Mol Genet (2008) 0.96
Pharmacogenomics of cisplatin-induced ototoxicity. Pharmacogenomics (2011) 0.92
Contribution of five amino acid residues in the glutathione-binding site to the function of human glutathione transferase P1-1. Biochem J (1992) 0.90
Comparison of the mRNA sequences for Pi class glutathione transferases in different hamster species and the corresponding enzyme activities with anti-benzo[a]pyrene-7,8-dihydrodiol 9,10-epoxide. Biochem J (1996) 0.82
Role of GSTM1 in resistance to lung inflammation. Free Radic Biol Med (2012) 0.81
Polymorphisms in the CYP2E1 and GSTM1 genes as possible protection factors for leprosy patients. PLoS One (2012) 0.80
Structural determinants in domain II of human glutathione transferase M2-2 govern the characteristic activities with aminochrome, 2-cyano-1,3-dimethyl-1-nitrosoguanidine, and 1,2-dichloro-4-nitrobenzene. Protein Sci (1999) 0.77
Human pharmacogenomic variations and their implications for antifungal efficacy. Clin Microbiol Rev (2006) 0.75
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54
A simplification of the protein assay method of Lowry et al. which is more generally applicable. Anal Biochem (1977) 36.95
The rapid generation of oligonucleotide-directed mutations at high frequency using phosphorothioate-modified DNA. Nucleic Acids Res (1985) 12.11
Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties. Proc Natl Acad Sci U S A (1985) 6.20
"ATG vectors' for regulated high-level expression of cloned genes in Escherichia coli. Gene (1985) 4.48
Hereditary differences in the expression of the human glutathione transferase active on trans-stilbene oxide are due to a gene deletion. Proc Natl Acad Sci U S A (1988) 3.75
Glutathione transferase (human placenta). Methods Enzymol (1981) 3.59
Biochemical genetics of glutathione-S-transferase in man. Am J Hum Genet (1981) 2.57
A glutathione transferase in human leukocytes as a marker for the susceptibility to lung cancer. Carcinogenesis (1986) 2.09
Molecular and catalytic properties of glutathione transferase mu from human liver: an enzyme efficiently conjugating epoxides. Biochemistry (1983) 2.08
Studies on the inhibition of glyoxalase I by S-substituted glutathiones. J Med Chem (1971) 1.97
The human glutathione S-transferases: studies on the tissue distribution and genetic variation of the GST1, GST2 and GST3 isozymes. Ann Hum Genet (1984) 1.85
Interrelationship between anionic and cationic forms of glutathione S-transferases of human liver. Biochem J (1980) 1.47
Purification of a new glutathione S-transferase (transferase mu) from human liver having high activity with benzo(alpha)pyrene-4,5-oxide. Biochem Biophys Res Commun (1981) 1.28
Selective expression of a unique glutathione S-transferase Yb3 gene in rat brain. J Biol Chem (1987) 1.27
The human liver glutathione S-transferase gene superfamily: expression and chromosome mapping of an Hb subunit cDNA. Nucleic Acids Res (1988) 1.27
Inhibitors for distinction of three types of human glutathione transferase. FEBS Lett (1985) 1.26
Structural evidence for three different types of glutathione transferase in human tissues. FEBS Lett (1985) 1.25
Expression of human glutathione S-transferase 2 in Escherichia coli. Immunological comparison with the basic glutathione S-transferases isoenzymes from human liver. Biochem J (1987) 1.21
Structure of human glutathione S-transferase class Mu genes. Biochem J (1991) 1.19
Denitrosation of 1,3-bis(2-chloroethyl)-1-nitrosourea by class mu glutathione transferases and its role in cellular resistance in rat brain tumor cells. Cancer Res (1989) 1.12
Simple inhibition studies for distinction between homodimeric and heterodimeric isoenzymes of glutathione transferase. J Biol Chem (1986) 1.09
Identification of a new glutathione S-transferase in human liver. Acta Chem Scand B (1980) 1.05
Expression of a cDNA encoding a rat liver glutathione S-transferase Ya subunit in Escherichia coli. Arch Biochem Biophys (1989) 1.00
Rat, mouse and hamster isozyme specificity in the glutathione transferase-mediated denitrosation of nitrosoguanidinium compounds. Cancer Res (1990) 0.91
Construction, expression, and preliminary characterization of chimeric class mu glutathione S-transferases with altered catalytic properties. Biopolymers (1990) 0.90
Characterization of a variant rat glutathione S-transferase by cDNA expression in Escherichia coli. Arch Biochem Biophys (1989) 0.86
Expression of an enzymatically active Yb3 glutathione S-transferase in Escherichia coli and identification of its natural form in rat brain. J Biol Chem (1988) 0.86
Expression in Escherichia coli of rat liver cytosolic glutathione S-transferase Yc cDNA. Arch Biochem Biophys (1990) 0.80
Rapid and sensitive protein similarity searches. Science (1985) 76.83
Aligning two sequences within a specified diagonal band. Comput Appl Biosci (1992) 19.31
Rapid and sensitive sequence comparison with FASTP and FASTA. Methods Enzymol (1990) 17.64
Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver. Biochim Biophys Acta (1979) 7.12
Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties. Proc Natl Acad Sci U S A (1985) 6.20
The isoenzymes of glutathione transferase. Adv Enzymol Relat Areas Mol Biol (1985) 5.91
Sequence and specificity of two antibacterial proteins involved in insect immunity. Nature (1981) 5.66
Glutathione reductase. Methods Enzymol (1985) 4.80
Hereditary differences in the expression of the human glutathione transferase active on trans-stilbene oxide are due to a gene deletion. Proc Natl Acad Sci U S A (1988) 3.75
Cannabis and schizophrenia. A longitudinal study of Swedish conscripts. Lancet (1987) 3.61
Glutathione transferase (human placenta). Methods Enzymol (1981) 3.59
Insect immunity. Attacins, a family of antibacterial proteins from Hyalophora cecropia. EMBO J (1983) 3.27
Insect immunity: isolation and structure of cecropin D and four minor antibacterial components from Cecropia pupae. Eur J Biochem (1982) 3.17
A program for least squares analysis of reassociation and hybridization data. Nucleic Acids Res (1977) 3.13
Purification and characterization of the flavoenzyme glutathione reductase from rat liver. J Biol Chem (1975) 2.96
Nomenclature for human glutathione transferases. Biochem J (1992) 2.71
Binary combinations of four protein subunits with different catalytic specificities explain the relationship between six basic glutathione S-transferases in rat liver cytosol. J Biol Chem (1982) 2.53
Identification of two juxtamembrane autophosphorylation sites in the PDGF beta-receptor; involvement in the interaction with Src family tyrosine kinases. EMBO J (1993) 2.46
4-Hydroxyalk-2-enals are substrates for glutathione transferase. FEBS Lett (1985) 2.21
Isolation and sequence of complementary DNA encoding human extracellular superoxide dismutase. Proc Natl Acad Sci U S A (1987) 2.20
Molecular and catalytic properties of glutathione transferase mu from human liver: an enzyme efficiently conjugating epoxides. Biochemistry (1983) 2.08
Glutathione transferases: nomenclature. Biochem Pharmacol (1984) 2.06
Detoxication of base propenals and other alpha, beta-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferases. Proc Natl Acad Sci U S A (1994) 2.02
The immune response in Drosophila: pattern of cecropin expression and biological activity. EMBO J (1990) 1.99
Automatic construction of restriction site maps. Nucleic Acids Res (1982) 1.92
Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue. Structure (1999) 1.89
Differences in the catalytic efficiencies of allelic variants of glutathione transferase P1-1 towards carcinogenic diol epoxides of polycyclic aromatic hydrocarbons. Carcinogenesis (1998) 1.88
A post-translational modification in the GGQ motif of RF2 from Escherichia coli stimulates termination of translation. EMBO J (2000) 1.87
Molecular cloning, cDNA sequencing, and chemical synthesis of cecropin B from Hyalophora cecropia. Proc Natl Acad Sci U S A (1985) 1.85
Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products. J Mol Biol (1999) 1.83
Empirical determination of effective gap penalties for sequence comparison. Bioinformatics (2002) 1.78
UGA is translated as cysteine in pheromone 3 of Euplotes octocarinatus. Proc Natl Acad Sci U S A (1991) 1.77
Human glutathione transferase A4-4: an alpha class enzyme with high catalytic efficiency in the conjugation of 4-hydroxynonenal and other genotoxic products of lipid peroxidation. Biochem J (1998) 1.76
Multiple antibody reactivities to citrullinated antigens in sera from patients with rheumatoid arthritis: association with HLA-DRB1 alleles. Ann Rheum Dis (2008) 1.71
Regression analysis, experimental error, and statistical criteria in the design and analysis of experiments for discrimination between rival kinetic models. Methods Enzymol (1982) 1.68
Increased synthesis of glutathione S-transferases in response to anticarcinogenic antioxidants. Cloning and measurement of messenger RNA. J Biol Chem (1983) 1.68
Isothiocyanates as substrates for human glutathione transferases: structure-activity studies. Biochem J (1995) 1.67
Evolution of protein sequences and structures. J Mol Biol (1999) 1.65
Glutathione transferases catalyse the detoxication of oxidized metabolites (o-quinones) of catecholamines and may serve as an antioxidant system preventing degenerative cellular processes. Biochem J (1997) 1.61
The solution conformation of the antibacterial peptide cecropin A: a nuclear magnetic resonance and dynamical simulated annealing study. Biochemistry (1988) 1.58
Rat glutathione transferase 8-8, an enzyme efficiently detoxifying 4-hydroxyalk-2-enals. FEBS Lett (1986) 1.57
Crystal structure of human glyoxalase I--evidence for gene duplication and 3D domain swapping. EMBO J (1997) 1.54
Purification of major basic glutathione transferase isoenzymes from rat liver by use of affinity chromatography and fast protein liquid chromatofocusing. Anal Biochem (1985) 1.49
T cell recognition of carbohydrates on type II collagen. J Exp Med (1994) 1.46
Cloning, expression, and characterization of a class-mu glutathione transferase from human muscle, the product of the GST4 locus. Proc Natl Acad Sci U S A (1991) 1.46
Endostatin-induced tyrosine kinase signaling through the Shb adaptor protein regulates endothelial cell apoptosis. Blood (2000) 1.45
Structure-activity relationships of 4-hydroxyalkenals in the conjugation catalysed by mammalian glutathione transferases. Biochem J (1987) 1.44
Reversible conjugation of isothiocyanates with glutathione catalyzed by human glutathione transferases. Biochem Biophys Res Commun (1995) 1.44
Glutathione peroxidase. Methods Enzymol (1985) 1.44
Mutation of an evolutionarily conserved tyrosine residue in the active site of a human class Alpha glutathione transferase. FEBS Lett (1991) 1.43
Expression of human extracellular superoxide dismutase in Chinese hamster ovary cells and characterization of the product. Proc Natl Acad Sci U S A (1987) 1.43
Purification and characterization of two glutathione S-aryltransferase activities from rat liver. Biochem J (1975) 1.43
Single-step purification and h.p.l.c. analysis of glutathione transferase 8-8 in rat tissues. Biochem J (1989) 1.39
Structure-activity relationships and thermal stability of human glutathione transferase P1-1 governed by the H-site residue 105. J Mol Biol (1998) 1.36
Missense mutations in the human glutathione synthetase gene result in severe metabolic acidosis, 5-oxoprolinuria, hemolytic anemia and neurological dysfunction. Hum Mol Genet (1997) 1.36
The andropin gene and its product, a male-specific antibacterial peptide in Drosophila melanogaster. EMBO J (1991) 1.35
Structural analysis of human alpha-class glutathione transferase A1-1 in the apo-form and in complexes with ethacrynic acid and its glutathione conjugate. Structure (1995) 1.35
Insect immunity: isolation and structure of cecropins B and D from pupae of the Chinese oak silk moth, Antheraea pernyi. Eur J Biochem (1982) 1.35
Error structure of enzyme kinetic experiments. Implications for weighting in regression analysis of experimental data. Eur J Biochem (1976) 1.34
Purification and characterization of three distinct glutathione transferases from mouse liver. Biochemistry (1986) 1.32
Kinetic independence of the subunits of cytosolic glutathione transferase from the rat. Biochem J (1985) 1.32
Functional significance of arginine 15 in the active site of human class alpha glutathione transferase A1-1. J Mol Biol (1995) 1.30
Identification of an immunodominant type-II collagen peptide recognized by T cells in H-2q mice: self tolerance at the level of determinant selection. Eur J Immunol (1992) 1.29
Purification of a new glutathione S-transferase (transferase mu) from human liver having high activity with benzo(alpha)pyrene-4,5-oxide. Biochem Biophys Res Commun (1981) 1.28
Characterization of a potassium channel toxin from the Caribbean Sea anemone Stichodactyla helianthus. Toxicon (1995) 1.27
Inhibitors for distinction of three types of human glutathione transferase. FEBS Lett (1985) 1.26
Purification of glutathione-S-transferase from human placenta. Acta Chem Scand B (1979) 1.25
Structural evidence for three different types of glutathione transferase in human tissues. FEBS Lett (1985) 1.25
Purification and characterization of a human neutrophil lipocalin (HNL) from the secondary granules of human neutrophils. Scand J Clin Lab Invest (1994) 1.23
Purification of glutathione S-transferases from rat lung by affinity chromatography. Evidence for an enzyme form absent in rat liver. Biochem Biophys Res Commun (1979) 1.23
Participation of the phenolic hydroxyl group of Tyr-8 in the catalytic mechanism of human glutathione transferase P1-1. Biochem J (1992) 1.23
Glutathione transferases from human liver. Methods Enzymol (1985) 1.23
Cytosolic rat liver glutathione transferase 4-4. Primary structure of the protein reveals extensive differences between homologous glutathione transferases of classes alpha and mu. Eur J Biochem (1986) 1.22
Identification of two expressed flagellin genes in the insect pathogen Bacillus thuringiensis subsp. alesti. J Gen Microbiol (1993) 1.22
Phospholipid hydroperoxide glutathione peroxidase activity of human glutathione transferases. Biochem J (1998) 1.22
The origin of nuclear receptor proteins: a single precursor distinct from other transcription factors. Mol Endocrinol (1992) 1.21
Regulation of synthesis of amyloid A-related protein. Ann N Y Acad Sci (1982) 1.20
Molecular characterization of immune inhibitor A, a secreted virulence protease from Bacillus thuringiensis. Mol Microbiol (1990) 1.20
The antibacterial effect of attacins from the silk moth Hyalophora cecropia is directed against the outer membrane of Escherichia coli. EMBO J (1984) 1.19
Glutathione transferase from rat testis. Methods Enzymol (1985) 1.19
Cytosolic glutathione transferases from rat liver. Primary structure of class alpha glutathione transferase 8-8 and characterization of low-abundance class Mu glutathione transferases. Biochem J (1989) 1.19
Glutathione transferases in rat testis. Acta Chem Scand B (1983) 1.18
Reaction mechanism of glyoxalase I explored by an X-ray crystallographic analysis of the human enzyme in complex with a transition state analogue. Biochemistry (1999) 1.18
Purification and characterization of cytoplasmic thioltransferase (glutathione:disulfide oxidoreductase) from rat liver. Biochemistry (1978) 1.18
A steady-state-kinetic random mechanism for glutathione S-transferase A from rat liver. A model involving kinetically significant enzyme-product complexes in the forward reaction. Eur J Biochem (1977) 1.17
A platform for biological sequence comparison on parallel computers. Comput Appl Biosci (1991) 1.16
Analysis of rat repetitive DNA sequences. Biochemistry (1978) 1.16
Identification of murine loci associated with susceptibility to chronic experimental autoimmune encephalomyelitis. Nat Genet (1995) 1.15
The trans-stilbene oxide-active glutathione transferase in human mononuclear leucocytes is identical with the hepatic glutathione transferase mu. Biochem J (1987) 1.14
Absence of short period interspersion of repetitive and non-repetitive sequences in the DNA of Drosophila melanogaster. Chromosoma (1976) 1.14
Glutathione S-transferase (transferase pi) from human placenta is identical or closely related to glutathione S-transferase (transferase rho) from erythrocytes. Biochim Biophys Acta (1981) 1.14
Isoenzymes of glutathione transferase in rat kidney cytosol. Biochem J (1985) 1.13
A procedure based on statistical criteria for discrimination between steady state kinetic models. FEBS Lett (1972) 1.13
Glutathione transferase activity and isoenzyme composition in primary human breast cancers. Cancer Res (1990) 1.12
Denitrosation of 1,3-bis(2-chloroethyl)-1-nitrosourea by class mu glutathione transferases and its role in cellular resistance in rat brain tumor cells. Cancer Res (1989) 1.12
Characterization of the human class Mu glutathione S-transferase gene cluster and the GSTM1 deletion. J Biol Chem (1998) 1.11
Human glutathione transferase A3-3, a highly efficient catalyst of double-bond isomerization in the biosynthetic pathway of steroid hormones. J Biol Chem (2001) 1.11