Published in J Bone Miner Res on October 01, 2010
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Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism. Nat Genet (2006) 7.53
DMP1 mutations in autosomal recessive hypophosphatemia implicate a bone matrix protein in the regulation of phosphate homeostasis. Nat Genet (2006) 4.49
Deletion of dentin matrix protein-1 leads to a partial failure of maturation of predentin into dentin, hypomineralization, and expanded cavities of pulp and root canal during postnatal tooth development. J Biol Chem (2004) 3.21
Dentin sialophosphoprotein knockout mouse teeth display widened predentin zone and develop defective dentin mineralization similar to human dentinogenesis imperfecta type III. J Biol Chem (2003) 3.03
Dentinogenesis imperfecta 1 with or without progressive hearing loss is associated with distinct mutations in DSPP. Nat Genet (2001) 2.75
Dmp1-deficient mice display severe defects in cartilage formation responsible for a chondrodysplasia-like phenotype. J Biol Chem (2004) 2.70
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DMP1 depletion decreases bone mineralization in vivo: an FTIR imaging analysis. J Bone Miner Res (2005) 2.46
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FGF23 and disorders of phosphate homeostasis. Cytokine Growth Factor Rev (2005) 1.79
Anti-FGF23 neutralizing antibodies show the physiological role and structural features of FGF23. J Bone Miner Res (2008) 1.75
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A comprehensive analysis of normal variation and disease-causing mutations in the human DSPP gene. Hum Mutat (2008) 1.41
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Molecular analysis of DMP1 mutants causing autosomal recessive hypophosphatemic rickets. Bone (2008) 1.20
Phenotypes and genotypes in 2 DGI families with different DSPP mutations. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2006) 1.15
Periodontal breakdown in the Dmp1 null mouse model of hypophosphatemic rickets. J Dent Res (2008) 1.14
New cellular models for tracking the odontoblast phenotype. Arch Oral Biol (2004) 1.07
Col1a1-GFP transgene expression in developing incisors. Connect Tissue Res (2002) 1.07
Overlapping DSPP mutations cause dentin dysplasia and dentinogenesis imperfecta. J Dent Res (2008) 1.06
Spatial and temporal activity of the dentin sialophosphoprotein gene promoter: differential regulation in odontoblasts and ameloblasts. Int J Dev Biol (1999) 1.02
Genetic and clinical peculiarities in a new family with hereditary hypophosphatemic rickets with hypercalciuria: a case report. Orphanet J Rare Dis (2010) 0.96
Identification of a novel dentin matrix protein-1 (DMP-1) mutation and dental anomalies in a kindred with autosomal recessive hypophosphatemia. Bone (2009) 0.95
New insight into progenitor/stem cells in dental pulp using Col1a1-GFP transgenes. Cells Tissues Organs (2004) 0.93
Do osteocytes contribute to phosphate homeostasis? Curr Opin Nephrol Hypertens (2009) 0.82
Identification of the haematopoietic stem cell niche and control of the niche size. Nature (2003) 18.17
Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism. Nat Genet (2006) 7.53
Evidence for osteocyte regulation of bone homeostasis through RANKL expression. Nat Med (2011) 5.66
The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice. Science (2011) 4.76
Deletion of dentin matrix protein-1 leads to a partial failure of maturation of predentin into dentin, hypomineralization, and expanded cavities of pulp and root canal during postnatal tooth development. J Biol Chem (2004) 3.21
periostin null mice exhibit dwarfism, incisor enamel defects, and an early-onset periodontal disease-like phenotype. Mol Cell Biol (2005) 2.94
Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis. Mol Cell Biol (2010) 2.85
Dmp1-deficient mice display severe defects in cartilage formation responsible for a chondrodysplasia-like phenotype. J Biol Chem (2004) 2.70
Dual energy X-ray absorptiometry interpretation and reporting in children and adolescents: the 2007 ISCD Pediatric Official Positions. J Clin Densitom (2008) 2.64
Osteogenesis imperfecta type VI: a form of brittle bone disease with a mineralization defect. J Bone Miner Res (2002) 2.56
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Dentin matrix protein 1, a target molecule for Cbfa1 in bone, is a unique bone marker gene. J Bone Miner Res (2002) 2.36
In vitro effects of dentin matrix protein-1 on hydroxyapatite formation provide insights into in vivo functions. J Biol Chem (2004) 2.25
Multiple functions of Osterix are required for bone growth and homeostasis in postnatal mice. Proc Natl Acad Sci U S A (2010) 2.20
Inactivation of a novel FGF23 regulator, FAM20C, leads to hypophosphatemic rickets in mice. PLoS Genet (2012) 2.19
Matrix macromolecules in hard tissues control the nucleation and hierarchical assembly of hydroxyapatite. J Biol Chem (2006) 2.13
Normocalcemia is maintained in mice under conditions of calcium malabsorption by vitamin D-induced inhibition of bone mineralization. J Clin Invest (2012) 2.10
Bone morphogenetic protein signaling inhibits hair follicle anagen induction by restricting epithelial stem/progenitor cell activation and expansion. Stem Cells (2006) 2.09
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Extracellular matrix made by bone marrow cells facilitates expansion of marrow-derived mesenchymal progenitor cells and prevents their differentiation into osteoblasts. J Bone Miner Res (2007) 1.99
Normal and disease-related biological functions of Twist1 and underlying molecular mechanisms. Cell Res (2011) 1.99
E11/gp38 selective expression in osteocytes: regulation by mechanical strain and role in dendrite elongation. Mol Cell Biol (2006) 1.98
Sensitivity of fibroblast growth factor 23 measurements in tumor-induced osteomalacia. J Clin Endocrinol Metab (2006) 1.91
BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development (2008) 1.86
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Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) signaling. FASEB J (2011) 1.74
Spatially and temporally controlled biomineralization is facilitated by interaction between self-assembled dentin matrix protein 1 and calcium phosphate nuclei in solution. Biochemistry (2005) 1.68
Deletion of the NESP55 differentially methylated region causes loss of maternal GNAS imprints and pseudohypoparathyroidism type Ib. Nat Genet (2004) 1.68
Mechanical loading stimulates dentin matrix protein 1 (DMP1) expression in osteocytes in vivo. J Bone Miner Res (2003) 1.66
Clinical review 1: Bisphosphonate use in childhood osteoporosis. J Clin Endocrinol Metab (2008) 1.62
Dentin matrix protein 1 gene cis-regulation: use in osteocytes to characterize local responses to mechanical loading in vitro and in vivo. J Biol Chem (2005) 1.57
Cartilage oligomeric matrix protein associates with granulin-epithelin precursor (GEP) and potentiates GEP-stimulated chondrocyte proliferation. J Biol Chem (2007) 1.55
Pathogenic role of Fgf23 in Dmp1-null mice. Am J Physiol Endocrinol Metab (2008) 1.55
Disruption of BMP signaling in osteoblasts through type IA receptor (BMPRIA) increases bone mass. J Bone Miner Res (2008) 1.54
Granulin epithelin precursor: a bone morphogenic protein 2-inducible growth factor that activates Erk1/2 signaling and JunB transcription factor in chondrogenesis. FASEB J (2010) 1.53
Colocalization of dentin matrix protein 1 and dentin sialoprotein at late stages of rat molar development. Matrix Biol (2004) 1.49
Identification of full-length dentin matrix protein 1 in dentin and bone. Calcif Tissue Int (2008) 1.44
The biological function of DMP-1 in osteocyte maturation is mediated by its 57-kDa C-terminal fragment. J Bone Miner Res (2011) 1.42
Functional consequences of interactions between Pax9 and Msx1 genes in normal and abnormal tooth development. J Biol Chem (2006) 1.41
Detection of dentin sialoprotein in rat periodontium. Eur J Oral Sci (2004) 1.38
Aberrant Phex function in osteoblasts and osteocytes alone underlies murine X-linked hypophosphatemia. J Clin Invest (2008) 1.38
Expression of FAM20C in the osteogenesis and odontogenesis of mouse. J Histochem Cytochem (2010) 1.33
Osteoblast lineage-specific effects of notch activation in the skeleton. Endocrinology (2012) 1.32
FAM20C plays an essential role in the formation of murine teeth. J Biol Chem (2012) 1.29
Dentin sialophosphoprotein in biomineralization. Connect Tissue Res (2010) 1.29
Unique roles of phosphorus in endochondral bone formation and osteocyte maturation. J Bone Miner Res (2011) 1.29
Studies of the DMP1 57-kDa functional domain both in vivo and in vitro. Cells Tissues Organs (2008) 1.26
Genetic evidence for the vital function of Osterix in cementogenesis. J Bone Miner Res (2012) 1.26
Extracellular matrix proteins and the dynamics of dentin formation. Connect Tissue Res (2002) 1.26
Estrogen receptor-α in osteocytes is important for trabecular bone formation in male mice. Proc Natl Acad Sci U S A (2013) 1.26
Advanced vertebral fracture among newly diagnosed children with acute lymphoblastic leukemia: results of the Canadian Steroid-Associated Osteoporosis in the Pediatric Population (STOPP) research program. J Bone Miner Res (2009) 1.24
Distribution of SIBLING proteins in the organic and inorganic phases of rat dentin and bone. Eur J Oral Sci (2008) 1.22
Molecular analysis of DMP1 mutants causing autosomal recessive hypophosphatemic rickets. Bone (2008) 1.20
Dentin extracellular matrix (ECM) proteins: comparison to bone ECM and contribution to dynamics of dentinogenesis. Connect Tissue Res (2003) 1.20
A nerve graft constructed with xenogeneic acellular nerve matrix and autologous adipose-derived mesenchymal stem cells. Biomaterials (2010) 1.20
The NH2-terminal and COOH-terminal fragments of dentin matrix protein 1 (DMP1) localize differently in the compartments of dentin and growth plate of bone. J Histochem Cytochem (2008) 1.19
Osteoclast precursor interaction with bone matrix induces osteoclast formation directly by an interleukin-1-mediated autocrine mechanism. J Biol Chem (2008) 1.16
Failure to process dentin matrix protein 1 (DMP1) into fragments leads to its loss of function in osteogenesis. J Biol Chem (2010) 1.10
Incident vertebral fractures among children with rheumatic disorders 12 months after glucocorticoid initiation: a national observational study. Arthritis Care Res (Hoboken) (2012) 1.09
Inflammatory and immunological aspects of dental pulp repair. Pharmacol Res (2008) 1.09
Essential role of osterix for tooth root but not crown dentin formation. J Bone Miner Res (2015) 1.07
Distinct compartmentalization of dentin matrix protein 1 fragments in mineralized tissues and cells. Cells Tissues Organs (2008) 1.07
High incidence of vertebral fractures in children with acute lymphoblastic leukemia 12 months after the initiation of therapy. J Clin Oncol (2012) 1.05
Incidence of vitamin D deficiency rickets among Australian children: an Australian Paediatric Surveillance Unit study. Med J Aust (2012) 1.05
A novel role of periostin in postnatal tooth formation and mineralization. J Biol Chem (2010) 1.03
The rescue of dentin matrix protein 1 (DMP1)-deficient tooth defects by the transgenic expression of dentin sialophosphoprotein (DSPP) indicates that DSPP is a downstream effector molecule of DMP1 in dentinogenesis. J Biol Chem (2013) 1.02
The impact of bioactive molecules to stimulate tooth repair and regeneration as part of restorative dentistry. Dent Clin North Am (2006) 1.01
Hexa-D-arginine treatment increases 7B2•PC2 activity in hyp-mouse osteoblasts and rescues the HYP phenotype. J Bone Miner Res (2013) 0.99
Expression of dentin sialophosphoprotein in non-mineralized tissues. J Histochem Cytochem (2011) 0.98
Preliminary evidence of early bone resorption in a sheep model of acute burn injury: an observational study. J Bone Miner Metab (2013) 0.96