DMP1 depletion decreases bone mineralization in vivo: an FTIR imaging analysis.

PubWeight™: 2.46‹?› | Rank: Top 2%

🔗 View Article (PMC 1456072)

Published in J Bone Miner Res on August 22, 2005

Authors

Yunfeng Ling1, Hector F Rios, Elizabeth R Myers, Yongbo Lu, Jian Q Feng, Adele L Boskey

Author Affiliations

1: Musculoskeletal Integrity Program, Hospital for Special Surgery, New York, New York, USA.

Articles citing this

Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism. Nat Genet (2006) 7.53

Phosphorylated proteins and control over apatite nucleation, crystal growth, and inhibition. Chem Rev (2008) 2.65

FT-IR imaging of native and tissue-engineered bone and cartilage. Biomaterials (2006) 2.27

Endocrine functions of bone in mineral metabolism regulation. J Clin Invest (2008) 2.19

Rescue of odontogenesis in Dmp1-deficient mice by targeted re-expression of DMP1 reveals roles for DMP1 in early odontogenesis and dentin apposition in vivo. Dev Biol (2006) 2.00

Signaling and transcriptional regulation in osteoblast commitment and differentiation. Front Biosci (2007) 1.61

Bone sialoprotein plays a functional role in bone formation and osteoclastogenesis. J Exp Med (2008) 1.54

The biological function of DMP-1 in osteocyte maturation is mediated by its 57-kDa C-terminal fragment. J Bone Miner Res (2011) 1.42

Callus mineralization and maturation are delayed during fracture healing in interleukin-6 knockout mice. Bone (2007) 1.34

Unique roles of phosphorus in endochondral bone formation and osteocyte maturation. J Bone Miner Res (2011) 1.29

A mouse model for human osteogenesis imperfecta type VI. J Bone Miner Res (2013) 1.27

Studies of the DMP1 57-kDa functional domain both in vivo and in vitro. Cells Tissues Organs (2008) 1.26

Dentin: structure, composition and mineralization. Front Biosci (Elite Ed) (2011) 1.23

Biominerals--hierarchical nanocomposites: the example of bone. Wiley Interdiscip Rev Nanomed Nanobiotechnol (2010) 1.20

Molecular analysis of DMP1 mutants causing autosomal recessive hypophosphatemic rickets. Bone (2008) 1.20

Aging and bone. J Dent Res (2010) 1.20

DSPP effects on in vivo bone mineralization. Bone (2008) 1.19

Correction of the mineralization defect in hyp mice treated with protease inhibitors CA074 and pepstatin. Bone (2006) 1.18

Direct transformation from amorphous to crystalline calcium phosphate facilitated by motif-programmed artificial proteins. Proc Natl Acad Sci U S A (2008) 1.17

Different forms of DMP1 play distinct roles in mineralization. J Dent Res (2010) 1.15

Dentin matrix protein-1 isoforms promote differential cell attachment and migration. J Biol Chem (2008) 1.13

Primary structure and phosphorylation of dentin matrix protein 1 (DMP1) and dentin phosphophoryn (DPP) uniquely determine their role in biomineralization. Biomacromolecules (2011) 1.11

High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. J Bone Miner Res (2009) 1.09

Recent advances in renal phosphate handling. Nat Rev Nephrol (2010) 1.04

Wnt11 promotes osteoblast maturation and mineralization through R-spondin 2. J Biol Chem (2009) 1.01

Dentin matrix protein 1 (DMP1) signals via cell surface integrin. J Biol Chem (2011) 0.99

Thrombospondin-2 and SPARC/osteonectin are critical regulators of bone remodeling. J Cell Commun Signal (2009) 0.98

Raman spectroscopy demonstrates prolonged alteration of bone chemical composition following extremity localized irradiation. Bone (2013) 0.98

Fetuin-A/albumin-mineral complexes resembling serum calcium granules and putative nanobacteria: demonstration of a dual inhibition-seeding concept. PLoS One (2009) 0.97

The rachitic tooth. Endocr Rev (2013) 0.96

Dentin sialophosphoprotein and dentin matrix protein-1: Two highly phosphorylated proteins in mineralized tissues. Arch Oral Biol (2012) 0.96

Identification of a novel dentin matrix protein-1 (DMP-1) mutation and dental anomalies in a kindred with autosomal recessive hypophosphatemia. Bone (2009) 0.95

Osteocyte regulation of phosphate homeostasis and bone mineralization underlies the pathophysiology of the heritable disorders of rickets and osteomalacia. Bone (2013) 0.94

DMP1 C-terminal mutant mice recapture the human ARHR tooth phenotype. J Bone Miner Res (2010) 0.94

Identification of osteocyte-selective proteins. Proteomics (2010) 0.93

Immunolocalization of sibling and RUNX2 proteins during vertical distraction osteogenesis in the human mandible. J Histochem Cytochem (2007) 0.93

Possible role of DMP1 in dentin mineralization. J Struct Biol (2010) 0.92

Overexpression of the DMP1 C-terminal fragment stimulates FGF23 and exacerbates the hypophosphatemic rickets phenotype in Hyp mice. Mol Endocrinol (2012) 0.91

Long-term clinical outcome and carrier phenotype in autosomal recessive hypophosphatemia caused by a novel DMP1 mutation. J Bone Miner Res (2010) 0.90

Phosphate: known and potential roles during development and regeneration of teeth and supporting structures. Birth Defects Res C Embryo Today (2008) 0.90

Generation of a conditional null allele for Dmp1 in mouse. Genesis (2008) 0.89

Skeletal adaptation to intramedullary pressure-induced interstitial fluid flow is enhanced in mice subjected to targeted osteocyte ablation. PLoS One (2012) 0.89

Overexpression of DMP1 accelerates mineralization and alters cortical bone biomechanical properties in vivo. J Mech Behav Biomed Mater (2011) 0.89

Inactivation of Lrp5 in osteocytes reduces young's modulus and responsiveness to the mechanical loading. Bone (2013) 0.88

Identification of secretory odontoblasts using DMP1-GFP transgenic mice. Bone (2010) 0.87

Osteogenic differentiation of human mesenchymal stem cells in mineralized alginate matrices. PLoS One (2015) 0.87

Characterization of dystrophic calcification induced in mice by cardiotoxin. Calcif Tissue Int (2009) 0.86

Midkine-deficiency delays chondrogenesis during the early phase of fracture healing in mice. PLoS One (2014) 0.85

Induced ablation of Bmp1 and Tll1 produces osteogenesis imperfecta in mice. Hum Mol Genet (2014) 0.83

Circling behavior developed in Dmp1 null mice is due to bone defects in the vestibular apparatus. Int J Biol Sci (2010) 0.83

Infrared imaging microscopy of bone: illustrations from a mouse model of Fabry disease. Biochim Biophys Acta (2006) 0.83

The role of acidic phosphoproteins in biomineralization. Connect Tissue Res (2014) 0.82

Do osteocytes contribute to phosphate homeostasis? Curr Opin Nephrol Hypertens (2009) 0.82

Molecular energy dissipation in nanoscale networks of Dentin Matrix Protein 1 is strongly dependent on ion valence. Nanotechnology (2008) 0.82

Ablation of cathepsin k activity in the young mouse causes hypermineralization of long bone and growth plates. Calcif Tissue Int (2009) 0.82

Female-specific induction of rat pituitary dentin matrix protein-1 by GnRH. Mol Endocrinol (2013) 0.81

Maturational changes in dentin mineral properties. Bone (2007) 0.81

Dentin matrix protein 1 and phosphate homeostasis are critical for postnatal pulp, dentin and enamel formation. Int J Oral Sci (2012) 0.80

Mineralization defects in cementum and craniofacial bone from loss of bone sialoprotein. Bone (2015) 0.80

Dentine matrix protein 1 (DMP-1) is a marker of bone-forming tumours. Virchows Arch (2013) 0.79

Deficiency in perlecan/HSPG2 during bone development enhances osteogenesis and decreases quality of adult bone in mice. Calcif Tissue Int (2014) 0.79

Effect of HIP/ribosomal protein L29 deficiency on mineral properties of murine bones and teeth. Bone (2010) 0.79

Microbeads-Guided Reconstruction of 3D Osteocyte Network during Microfluidic Perfusion Culture. J Mater Chem B Mater Biol Med (2015) 0.79

Transgenic expression of Dspp partially rescued the long bone defects of Dmp1-null mice. Matrix Biol (2015) 0.78

A dynamic history of gene duplications and losses characterizes the evolution of the SPARC family in eumetazoans. Proc Biol Sci (2013) 0.78

PTH and Vitamin D Repress DMP1 in Cementoblasts. J Dent Res (2015) 0.78

Ex vivo 3D osteocyte network construction with primary murine bone cells. Bone Res (2015) 0.78

The Role of Poly(Aspartic Acid) in the Precipitation of Calcium Phosphate in Confinement. J Mater Chem B Mater Biol Med (2013) 0.77

Role of the small integrin-binding ligand N-linked glycoprotein (SIBLING), bone sialoprotein (BSP) in bone development and remodeling. Osteoporos Int (2009) 0.77

Bone-specific overexpression of DMP1 influences osteogenic gene expression during endochondral and intramembranous ossification. Connect Tissue Res (2014) 0.77

Tantalum implanted entangled porous titanium promotes surface osseointegration and bone ingrowth. Sci Rep (2016) 0.77

The impairment of osteogenesis in bone sialoprotein (BSP) knockout calvaria cell cultures is cell density dependent. PLoS One (2015) 0.76

Matricellular proteins as regulators of cancer metastasis to bone. Matrix Biol (2016) 0.75

Skeletal Muscle, but not Cardiovascular Function, Is Altered in a Mouse Model of Autosomal Recessive Hypophosphatemic Rickets. Front Physiol (2016) 0.75

A novel auditory ossicles membrane and the development of conductive hearing loss in Dmp1-null mice. Bone (2017) 0.75

The recombinant human dentin matrix protein 1-coated titanium and its effect on the attachment, proliferation and ALP activity of MG63 cells. J Mater Sci Mater Med (2012) 0.75

Articles cited by this

MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes. Cell (1998) 9.70

Deletion of dentin matrix protein-1 leads to a partial failure of maturation of predentin into dentin, hypomineralization, and expanded cavities of pulp and root canal during postnatal tooth development. J Biol Chem (2004) 3.21

Six genes expressed in bones and teeth encode the current members of the SIBLING family of proteins. Connect Tissue Res (2003) 3.03

Post-translational modifications of sibling proteins and their roles in osteogenesis and dentinogenesis. Crit Rev Oral Biol Med (2004) 3.01

Nucleation and inhibition of hydroxyapatite formation by mineralized tissue proteins. Biochem J (1996) 2.89

The direct examination of three-dimensional bone architecture in vitro by computed tomography. J Bone Miner Res (1989) 2.89

Dmp1-deficient mice display severe defects in cartilage formation responsible for a chondrodysplasia-like phenotype. J Biol Chem (2004) 2.70

Characterization of a novel dentin matrix acidic phosphoprotein. Implications for induction of biomineralization. J Biol Chem (1993) 2.63

The Dentin matrix protein 1 (Dmp1) is specifically expressed in mineralized, but not soft, tissues during development. J Dent Res (2003) 2.48

Gene expression patterns of murine dentin matrix protein 1 (Dmp1) and dentin sialophosphoprotein (DSPP) suggest distinct developmental functions in vivo. J Bone Miner Res (1997) 2.46

Dentin matrix protein 1, a target molecule for Cbfa1 in bone, is a unique bone marker gene. J Bone Miner Res (2002) 2.36

Dentin matrix protein 1 expression during osteoblastic differentiation, generation of an osteocyte GFP-transgene. Bone (2004) 2.35

Spectroscopic characterization of collagen cross-links in bone. J Bone Miner Res (2001) 2.32

In vitro effects of dentin matrix protein-1 on hydroxyapatite formation provide insights into in vivo functions. J Biol Chem (2004) 2.25

Nucleation of apatite crystals in vitro by self-assembled dentin matrix protein 1. Nat Mater (2003) 2.25

Dentin matrix protein 1 is predominantly expressed in chicken and rat osteocytes but not in osteoblasts. J Bone Miner Res (2001) 2.06

Evidence for the proteolytic processing of dentin matrix protein 1. Identification and characterization of processed fragments and cleavage sites. J Biol Chem (2003) 2.04

Expression of SIBLINGs and their partner MMPs in salivary glands. J Dent Res (2004) 1.99

Differentiation of embryonic mesenchymal cells to odontoblast-like cells by overexpression of dentin matrix protein 1. Proc Natl Acad Sci U S A (2001) 1.85

Dentin matrix protein 1 immobilized on type I collagen fibrils facilitates apatite deposition in vitro. J Biol Chem (2003) 1.83

Bone morphogenetic protein-1/Tolloid-like proteinases process dentin matrix protein-1. J Biol Chem (2003) 1.80

Three small integrin binding ligand N-linked glycoproteins (SIBLINGs) bind and activate specific matrix metalloproteinases. FASEB J (2004) 1.79

Concentration-dependent effects of dentin phosphophoryn in the regulation of in vitro hydroxyapatite formation and growth. Bone Miner (1990) 1.70

Identification of a novel isoform of mouse dentin matrix protein 1: spatial expression in mineralized tissues. J Bone Miner Res (1998) 1.63

Infrared imaging of calcified tissue in bone biopsies from adults with osteomalacia. Bone (2004) 1.49

A comparative study of sialic acid-rich proteins in rat bone and dentin. Eur J Oral Sci (2001) 1.44

Small integrin binding ligand N-linked glycoprotein gene family expression in different cancers. Clin Cancer Res (2004) 1.43

Mechanism of calcification: role of collagen fibrils and collagen-phosphoprotein complexes in vitro and in vivo. Anat Rec (1989) 1.39

Genetic variation in structure-function relationships for the inbred mouse lumbar vertebral body. J Bone Miner Res (2004) 1.28

Cloning and expression analysis of the bovine dentin matrix acidic phosphoprotein gene. J Dent Res (1997) 1.24

Expression of dentin matrix protein 1 (DMP1) in nonmineralized tissues. J Bone Miner Metab (2004) 1.22

An interactive graphics package for calculating cross-sectional properties of complex shapes. J Biomech (1980) 1.06

Promotion of selective cell attachment by the RGD sequence in dentine matrix protein 1. Arch Oral Biol (2000) 1.03

Diffusion systems for evaluation of biomineralization. Calcif Tissue Int (2004) 1.03

Infrared microspectroscopic imaging of biomineralized tissues using a mercury-cadmium-telluride focal-plane array detector. Cell Mol Biol (Noisy-le-grand) (1998) 1.00

Osteopontin and related phosphorylated sialoproteins: effects on mineralization. Ann N Y Acad Sci (1995) 1.00

Infrared spectroscopy, microscopy, and microscopic imaging of mineralizing tissues: spectra-structure correlations from human iliac crest biopsies. J Biomed Opt (1999) 0.98

Expression of dentin matrix protein 1 in tumors causing oncogenic osteomalacia. Mod Pathol (2004) 0.95

Dentin matrix protein 1 is expressed in human lung cancer. J Bone Miner Res (2003) 0.94

Adaptations of Goldner's Masson trichrome stain for the study of undecalcified plastic embedded bone. Biotech Histochem (1992) 0.94

Expression of the dentin matrix protein 1 gene in birds. J Mol Evol (2000) 0.90

Transcriptional regulation of dentin matrix protein 1 by JunB and p300 during osteoblast differentiation. J Biol Chem (2004) 0.87

Treatment of proteoglycan aggregates with physeal enzymes reduces their ability to inhibit hydroxyapatite proliferation in a gelatin gel. J Orthop Res (1992) 0.86

Hydroxyapatite formation in the presence of proteoglycans of reduced sulfate content: studies in the brachymorphic mouse. Calcif Tissue Int (1991) 0.83

Renal sulfate secretion is carbonic anhydrase dependent in a marine teleost, Pleuronectes americanus. Am J Physiol (1999) 0.82

Articles by these authors

Identification of the haematopoietic stem cell niche and control of the niche size. Nature (2003) 18.17

Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism. Nat Genet (2006) 7.53

Evidence for osteocyte regulation of bone homeostasis through RANKL expression. Nat Med (2011) 5.66

The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice. Science (2011) 4.76

Deletion of dentin matrix protein-1 leads to a partial failure of maturation of predentin into dentin, hypomineralization, and expanded cavities of pulp and root canal during postnatal tooth development. J Biol Chem (2004) 3.21

periostin null mice exhibit dwarfism, incisor enamel defects, and an early-onset periodontal disease-like phenotype. Mol Cell Biol (2005) 2.94

Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis. Mol Cell Biol (2010) 2.85

Dmp1-deficient mice display severe defects in cartilage formation responsible for a chondrodysplasia-like phenotype. J Biol Chem (2004) 2.70

Dentin matrix protein 1, a target molecule for Cbfa1 in bone, is a unique bone marker gene. J Bone Miner Res (2002) 2.36

In vitro effects of dentin matrix protein-1 on hydroxyapatite formation provide insights into in vivo functions. J Biol Chem (2004) 2.25

Multiple functions of Osterix are required for bone growth and homeostasis in postnatal mice. Proc Natl Acad Sci U S A (2010) 2.20

Inactivation of a novel FGF23 regulator, FAM20C, leads to hypophosphatemic rickets in mice. PLoS Genet (2012) 2.19

Normocalcemia is maintained in mice under conditions of calcium malabsorption by vitamin D-induced inhibition of bone mineralization. J Clin Invest (2012) 2.10

Bone morphogenetic protein signaling inhibits hair follicle anagen induction by restricting epithelial stem/progenitor cell activation and expansion. Stem Cells (2006) 2.09

Reduced cortical bone compositional heterogeneity with bisphosphonate treatment in postmenopausal women with intertrochanteric and subtrochanteric fractures. J Bone Miner Res (2012) 2.05

Use of cone beam computed tomography in implant dentistry: the International Congress of Oral Implantologists consensus report. Implant Dent (2012) 2.04

Rescue of odontogenesis in Dmp1-deficient mice by targeted re-expression of DMP1 reveals roles for DMP1 in early odontogenesis and dentin apposition in vivo. Dev Biol (2006) 2.00

Extracellular matrix made by bone marrow cells facilitates expansion of marrow-derived mesenchymal progenitor cells and prevents their differentiation into osteoblasts. J Bone Miner Res (2007) 1.99

Bone loss caused by iron overload in a murine model: importance of oxidative stress. Blood (2010) 1.98

E11/gp38 selective expression in osteocytes: regulation by mechanical strain and role in dendrite elongation. Mol Cell Biol (2006) 1.98

BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development (2008) 1.86

Myelopoiesis is regulated by osteocytes through Gsα-dependent signaling. Blood (2012) 1.83

COL1 C-propeptide cleavage site mutations cause high bone mass osteogenesis imperfecta. Hum Mutat (2011) 1.77

Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) signaling. FASEB J (2011) 1.74

Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged mice. Aging Cell (2009) 1.72

Bone fragility and collagen cross-links. J Bone Miner Res (2004) 1.68

Mechanical loading stimulates dentin matrix protein 1 (DMP1) expression in osteocytes in vivo. J Bone Miner Res (2003) 1.66

Infrared assessment of bone quality: a review. Clin Orthop Relat Res (2011) 1.63

Does sex matter in musculoskeletal health? The influence of sex and gender on musculoskeletal health. J Bone Joint Surg Am (2005) 1.61

Variations in nanomechanical properties and tissue composition within trabeculae from an ovine model of osteoporosis and treatment. Bone (2012) 1.60

Dentin matrix protein 1 gene cis-regulation: use in osteocytes to characterize local responses to mechanical loading in vitro and in vivo. J Biol Chem (2005) 1.57

Cartilage oligomeric matrix protein associates with granulin-epithelin precursor (GEP) and potentiates GEP-stimulated chondrocyte proliferation. J Biol Chem (2007) 1.55

Pathogenic role of Fgf23 in Dmp1-null mice. Am J Physiol Endocrinol Metab (2008) 1.55

Use of FTIR spectroscopic imaging to identify parameters associated with fragility fracture. J Bone Miner Res (2009) 1.54

Disruption of BMP signaling in osteoblasts through type IA receptor (BMPRIA) increases bone mass. J Bone Miner Res (2008) 1.54

Spatial variation in osteonal bone properties relative to tissue and animal age. J Bone Miner Res (2009) 1.52

Bisphosphonate treatment modifies canine bone mineral and matrix properties and their heterogeneity. Bone (2009) 1.47

Effects of surface roughness and maximum load on the mechanical properties of cancellous bone measured by nanoindentation. J Biomed Mater Res A (2006) 1.46

Effects of tissue age on bone tissue material composition and nanomechanical properties in the rat cortex. J Biomed Mater Res A (2010) 1.45

Identification of full-length dentin matrix protein 1 in dentin and bone. Calcif Tissue Int (2008) 1.44

Combined bone morphogenetic protein-2 and -7 gene transfer enhances osteoblastic differentiation and spine fusion in a rodent model. J Bone Miner Res (2004) 1.42

The biological function of DMP-1 in osteocyte maturation is mediated by its 57-kDa C-terminal fragment. J Bone Miner Res (2011) 1.42

Functional consequences of interactions between Pax9 and Msx1 genes in normal and abnormal tooth development. J Biol Chem (2006) 1.41

Aberrant Phex function in osteoblasts and osteocytes alone underlies murine X-linked hypophosphatemia. J Clin Invest (2008) 1.38

Expression of FAM20C in the osteogenesis and odontogenesis of mouse. J Histochem Cytochem (2010) 1.33

Osteoblast lineage-specific effects of notch activation in the skeleton. Endocrinology (2012) 1.32

Dilatational band formation in bone. Proc Natl Acad Sci U S A (2012) 1.32

Infrared spectroscopic characterization of mineralized tissues. Vib Spectrosc (2005) 1.31

Mineral changes in osteoporosis: a review. Clin Orthop Relat Res (2006) 1.31

Contribution of mineral to bone structural behavior and tissue mechanical properties. Calcif Tissue Int (2010) 1.30

FAM20C plays an essential role in the formation of murine teeth. J Biol Chem (2012) 1.29

Unique roles of phosphorus in endochondral bone formation and osteocyte maturation. J Bone Miner Res (2011) 1.29

Fgfr4 is required for effective muscle regeneration in vivo. Delineation of a MyoD-Tead2-Fgfr4 transcriptional pathway. J Biol Chem (2005) 1.27

Studies of the DMP1 57-kDa functional domain both in vivo and in vitro. Cells Tissues Organs (2008) 1.26

Genetic evidence for the vital function of Osterix in cementogenesis. J Bone Miner Res (2012) 1.26

Estrogen receptor-α in osteocytes is important for trabecular bone formation in male mice. Proc Natl Acad Sci U S A (2013) 1.26

A novel regulatory role for stromal-derived factor-1 signaling in bone morphogenic protein-2 osteogenic differentiation of mesenchymal C2C12 cells. J Biol Chem (2007) 1.25

Bone mass is preserved and cancellous architecture altered due to cyclic loading of the mouse tibia after orchidectomy. J Bone Miner Res (2008) 1.25

In vivo cyclic axial compression affects bone healing in the mouse tibia. J Orthop Res (2006) 1.24

Composition of calcifications in children with juvenile dermatomyositis: association with chronic cutaneous inflammation. Arthritis Rheum (2006) 1.23

A nerve graft constructed with xenogeneic acellular nerve matrix and autologous adipose-derived mesenchymal stem cells. Biomaterials (2010) 1.20

DSPP effects on in vivo bone mineralization. Bone (2008) 1.19

In vivo RANK signaling blockade using the receptor activator of NF-kappaB:Fc effectively prevents and ameliorates wear debris-induced osteolysis via osteoclast depletion without inhibiting osteogenesis. J Bone Miner Res (2002) 1.17

Stromal derived factor-1 regulates bone morphogenetic protein 2-induced osteogenic differentiation of primary mesenchymal stem cells. Int J Biochem Cell Biol (2010) 1.17

Differential effects of alendronate treatment on bone from growing osteogenesis imperfecta and wild-type mouse. Bone (2005) 1.13

Tissue engineering bone-ligament complexes using fiber-guiding scaffolds. Biomaterials (2011) 1.12

Failure to process dentin matrix protein 1 (DMP1) into fragments leads to its loss of function in osteogenesis. J Biol Chem (2010) 1.10

Bone quality: from bench to bedside: opening editorial comment. Clin Orthop Relat Res (2011) 1.09

Brief bone morphogenetic protein 2 treatment of glucocorticoid-inhibited MC3T3-E1 osteoblasts rescues commitment-associated cell cycle and mineralization without alteration of Runx2. J Biol Chem (2003) 1.08

Fourier transform infrared imaging microspectroscopy and tissue-level mechanical testing reveal intraspecies variation in mouse bone mineral and matrix composition. Calcif Tissue Int (2008) 1.08

Cancellous bone adaptation to in vivo loading in a rabbit model. Bone (2006) 1.07

Essential role of osterix for tooth root but not crown dentin formation. J Bone Miner Res (2015) 1.07

Fourier transform-infrared microspectroscopy and microscopic imaging. Methods Mol Biol (2008) 1.06

A novel role of periostin in postnatal tooth formation and mineralization. J Biol Chem (2010) 1.03

Alendronate treatment for infants with osteogenesis imperfecta: demonstration of efficacy in a mouse model. Pediatr Res (2002) 1.03

Biomimetic hybrid scaffolds for engineering human tooth-ligament interfaces. Biomaterials (2010) 1.03

Microstructure and nanomechanical properties in osteons relate to tissue and animal age. J Biomech (2010) 1.03

The rescue of dentin matrix protein 1 (DMP1)-deficient tooth defects by the transgenic expression of dentin sialophosphoprotein (DSPP) indicates that DSPP is a downstream effector molecule of DMP1 in dentinogenesis. J Biol Chem (2013) 1.02

Conditional inactivation of the CXCR4 receptor in osteoprecursors reduces postnatal bone formation due to impaired osteoblast development. J Biol Chem (2011) 1.02

Bone morphogenetic protein-2 restores mineralization in glucocorticoid-inhibited MC3T3-E1 osteoblast cultures. J Bone Miner Res (2003) 1.02

Image-based, fiber guiding scaffolds: a platform for regenerating tissue interfaces. Tissue Eng Part C Methods (2013) 1.02

High-dose alendronate uncouples osteoclast and osteoblast function: a study in a rat spine pseudarthrosis model. Clin Orthop Relat Res (2004) 1.01

Spectroscopically determined collagen Pyr/deH-DHLNL cross-link ratio and crystallinity indices differ markedly in recombinant congenic mice with divergent calculated bone tissue strength. Connect Tissue Res (2003) 1.00

Fourier transform infrared imaging of femoral neck bone: reduced heterogeneity of mineral-to-matrix and carbonate-to-phosphate and more variable crystallinity in treatment-naive fracture cases compared with fracture-free controls. J Bone Miner Res (2013) 0.99

Hexa-D-arginine treatment increases 7B2•PC2 activity in hyp-mouse osteoblasts and rescues the HYP phenotype. J Bone Miner Res (2013) 0.99

Expression of dentin sialophosphoprotein in non-mineralized tissues. J Histochem Cytochem (2011) 0.98

Decorin modulates collagen matrix assembly and mineralization. Matrix Biol (2008) 0.98

Bone mineral and collagen quality in humeri of ovariectomized cynomolgus monkeys given rhPTH(1-34) for 18 months. J Bone Miner Res (2003) 0.97

FGF23 in skeletal modeling and remodeling. Curr Osteoporos Rep (2011) 0.96

Critical role of calbindin-D28k in calcium homeostasis revealed by mice lacking both vitamin D receptor and calbindin-D28k. J Biol Chem (2004) 0.95

Bone tissue composition varies across anatomic sites in the proximal femur and the iliac crest. J Orthop Res (2011) 0.95

Proteolytic processing of dentin sialophosphoprotein (DSPP) is essential to dentinogenesis. J Biol Chem (2012) 0.94