1
|
Pre-steady-state kinetic studies of the fidelity of Sulfolobus solfataricus P2 DNA polymerase IV.
|
Biochemistry
|
2004
|
1.57
|
2
|
Unlocking the sugar "steric gate" of DNA polymerases.
|
Biochemistry
|
2011
|
1.56
|
3
|
Mechanism of DNA polymerization catalyzed by Sulfolobus solfataricus P2 DNA polymerase IV.
|
Biochemistry
|
2004
|
1.52
|
4
|
Snapshots of a Y-family DNA polymerase in replication: substrate-induced conformational transitions and implications for fidelity of Dpo4.
|
J Mol Biol
|
2008
|
1.29
|
5
|
Pre-steady-state kinetic studies of the fidelity and mechanism of polymerization catalyzed by truncated human DNA polymerase lambda.
|
Biochemistry
|
2004
|
1.25
|
6
|
Mechanism of abasic lesion bypass catalyzed by a Y-family DNA polymerase.
|
J Biol Chem
|
2007
|
1.23
|
7
|
A novel mechanism of sugar selection utilized by a human X-family DNA polymerase.
|
J Mol Biol
|
2009
|
1.20
|
8
|
Single-turnover kinetic analysis of the mutagenic potential of 8-oxo-7,8-dihydro-2'-deoxyguanosine during gap-filling synthesis catalyzed by human DNA polymerases lambda and beta.
|
J Mol Biol
|
2007
|
1.14
|
9
|
Mechanism of template-independent nucleotide incorporation catalyzed by a template-dependent DNA polymerase.
|
J Mol Biol
|
2006
|
1.14
|
10
|
Sloppy bypass of an abasic lesion catalyzed by a Y-family DNA polymerase.
|
J Biol Chem
|
2007
|
1.07
|
11
|
Up-regulation of the fidelity of human DNA polymerase lambda by its non-enzymatic proline-rich domain.
|
J Biol Chem
|
2006
|
1.06
|
12
|
Global conformational dynamics of a Y-family DNA polymerase during catalysis.
|
PLoS Biol
|
2009
|
1.05
|
13
|
Pre-steady-state kinetic studies of the fidelity of human DNA polymerase mu.
|
Biochemistry
|
2004
|
1.00
|
14
|
Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4.
|
EMBO J
|
2010
|
0.98
|
15
|
Mechanism of double-base lesion bypass catalyzed by a Y-family DNA polymerase.
|
Nucleic Acids Res
|
2008
|
0.97
|
16
|
Quantitative analysis of the efficiency and mutagenic spectra of abasic lesion bypass catalyzed by human Y-family DNA polymerases.
|
Nucleic Acids Res
|
2010
|
0.96
|
17
|
Polymerization fidelity of a replicative DNA polymerase from the hyperthermophilic archaeon Sulfolobus solfataricus P2.
|
Biochemistry
|
2009
|
0.95
|
18
|
Kinetic basis of nucleotide selection employed by a protein template-dependent DNA polymerase.
|
Biochemistry
|
2010
|
0.94
|
19
|
Kinetic investigation of the inhibitory effect of gemcitabine on DNA polymerization catalyzed by human mitochondrial DNA polymerase.
|
J Biol Chem
|
2008
|
0.94
|
20
|
Mechanistic studies of the bypass of a bulky single-base lesion catalyzed by a Y-family DNA polymerase.
|
J Biol Chem
|
2009
|
0.93
|
21
|
Kinetic analysis of the bypass of a bulky DNA lesion catalyzed by human Y-family DNA polymerases.
|
Chem Res Toxicol
|
2012
|
0.93
|
22
|
Kinetic basis for the differing response to an oxidative lesion by a replicative and a lesion bypass DNA polymerase from Sulfolobus solfataricus.
|
Biochemistry
|
2012
|
0.91
|
23
|
Mechanistic consequences of temperature on DNA polymerization catalyzed by a Y-family DNA polymerase.
|
Nucleic Acids Res
|
2008
|
0.91
|
24
|
Human DNA polymerase ε is able to efficiently extend from multiple consecutive ribonucleotides.
|
J Biol Chem
|
2012
|
0.91
|
25
|
Kinetic basis of sugar selection by a Y-family DNA polymerase from Sulfolobus solfataricus P2.
|
Biochemistry
|
2010
|
0.90
|
26
|
Multidomain protein solves the folding problem by multifunnel combined landscape: theoretical investigation of a Y-family DNA polymerase.
|
J Am Chem Soc
|
2012
|
0.90
|
27
|
Efficiency and fidelity of human DNA polymerases λ and β during gap-filling DNA synthesis.
|
DNA Repair (Amst)
|
2010
|
0.90
|
28
|
Pre-steady-state kinetic analysis of the incorporation of anti-HIV nucleotide analogs catalyzed by human X- and Y-family DNA polymerases.
|
Antimicrob Agents Chemother
|
2010
|
0.89
|
29
|
Elucidating the kinetic mechanism of DNA polymerization catalyzed by Sulfolobus solfataricus P2 DNA polymerase B1.
|
Biochemistry
|
2009
|
0.89
|
30
|
Structural mechanism of ribonucleotide discrimination by a Y-family DNA polymerase.
|
J Mol Biol
|
2011
|
0.89
|
31
|
Biochemical, structural, and physiological characterization of terminal deoxynucleotidyl transferase.
|
Chem Rev
|
2006
|
0.89
|
32
|
Recent insight into the kinetic mechanisms and conformational dynamics of Y-Family DNA polymerases.
|
Biochemistry
|
2014
|
0.88
|
33
|
Low fidelity bypass of O(2)-(3-pyridyl)-4-oxobutylthymine, the most persistent bulky adduct produced by the tobacco specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by model DNA polymerases.
|
Chem Res Toxicol
|
2012
|
0.88
|
34
|
Kinetic effect of a downstream strand and its 5'-terminal moieties on single nucleotide gap-filling synthesis catalyzed by human DNA polymerase lambda.
|
J Biol Chem
|
2006
|
0.87
|
35
|
DNA lesion alters global conformational dynamics of Y-family DNA polymerase during catalysis.
|
J Biol Chem
|
2012
|
0.86
|
36
|
Preparation of site-specific T=mCG cis-syn cyclobutane dimer-containing template and its error-free bypass by yeast and human polymerase η.
|
J Biol Chem
|
2012
|
0.85
|
37
|
Kinetic mechanism of DNA polymerization catalyzed by human DNA polymerase ε.
|
Biochemistry
|
2013
|
0.83
|
38
|
Probing conformational changes of human DNA polymerase lambda using mass spectrometry-based protein footprinting.
|
J Mol Biol
|
2009
|
0.82
|
39
|
Pre-Steady-State Kinetic Analysis of Truncated and Full-Length Saccharomyces cerevisiae DNA Polymerase Eta.
|
J Nucleic Acids
|
2010
|
0.82
|
40
|
Mutagenic potential of 8-oxo-7,8-dihydro-2'-deoxyguanosine bypass catalyzed by human Y-family DNA polymerases.
|
Chem Res Toxicol
|
2014
|
0.81
|
41
|
Quantitative analysis of the mutagenic potential of 1-aminopyrene-DNA adduct bypass catalyzed by Y-family DNA polymerases.
|
Mutat Res
|
2012
|
0.81
|
42
|
Single-molecule investigation of substrate binding kinetics and protein conformational dynamics of a B-family replicative DNA polymerase.
|
J Biol Chem
|
2013
|
0.81
|
43
|
Presteady state kinetic investigation of the incorporation of anti-hepatitis B nucleotide analogues catalyzed by noncanonical human DNA polymerases.
|
Chem Res Toxicol
|
2011
|
0.81
|
44
|
A high-throughput and quantitative method to assess the mutagenic potential of translesion DNA synthesis.
|
Nucleic Acids Res
|
2013
|
0.80
|
45
|
Identification of critical residues for the tight binding of both correct and incorrect nucleotides to human DNA polymerase λ.
|
J Mol Biol
|
2010
|
0.80
|
46
|
Conformational dynamics of a Y-family DNA polymerase during substrate binding and catalysis as revealed by interdomain Förster resonance energy transfer.
|
Biochemistry
|
2014
|
0.79
|
47
|
Formation of purine-purine mispairs by Sulfolobus solfataricus DNA polymerase IV.
|
Biochemistry
|
2008
|
0.79
|
48
|
Following DNA chain extension and protein conformational changes in crystals of a Y-family DNA polymerase via Raman crystallography.
|
Biochemistry
|
2013
|
0.79
|
49
|
Mechanistic Basis for the Bypass of a Bulky DNA Adduct Catalyzed by a Y-Family DNA Polymerase.
|
J Am Chem Soc
|
2015
|
0.78
|
50
|
Identification of an unfolding intermediate for a DNA lesion bypass polymerase.
|
Chem Res Toxicol
|
2012
|
0.77
|
51
|
Direct probing of solvent accessibility and mobility at the binding interface of polymerase (Dpo4)-DNA complex.
|
J Phys Chem A
|
2013
|
0.76
|
52
|
Backbone assignment of the little finger domain of a Y-family DNA polymerase.
|
Biomol NMR Assign
|
2011
|
0.76
|
53
|
Backbone assignment of the catalytic core of a Y-family DNA polymerase.
|
Biomol NMR Assign
|
2010
|
0.76
|
54
|
Long-Term Survival of AIDS Patients Treated with Only Traditional Chinese Medicine.
|
Altern Complement Ther
|
2017
|
0.75
|