PubRank

Judith Klumperman

Author PubWeight™ 103.10‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Termination of autophagy and reformation of lysosomes regulated by mTOR. Nature 2010 6.26
2 Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function. Nat Rev Mol Cell Biol 2009 4.16
3 Sorting nexin-1 mediates tubular endosome-to-TGN transport through coincidence sensing of high- curvature membranes and 3-phosphoinositides. Curr Biol 2004 3.76
4 Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents. J Cell Biol 2008 3.36
5 Bilayered clathrin coats on endosomal vacuoles are involved in protein sorting toward lysosomes. Mol Biol Cell 2002 3.24
6 Autophagy proteins regulate the secretory component of osteoclastic bone resorption. Dev Cell 2011 2.84
7 Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins. J Cell Biol 2004 2.76
8 Trafficking and function of the tetraspanin CD63. Exp Cell Res 2008 2.64
9 Endocytosis and sorting of ErbB2 and the site of action of cancer therapeutics trastuzumab and geldanamycin. Mol Biol Cell 2004 2.60
10 EGFL7 regulates the collective migration of endothelial cells by restricting their spatial distribution. Development 2007 2.45
11 Sunday Driver links axonal transport to damage signaling. J Cell Biol 2005 2.29
12 The UIM domain of Hrs couples receptor sorting to vesicle formation. J Cell Sci 2003 1.97
13 Pre- and post-Golgi translocation of glucosylceramide in glycosphingolipid synthesis. J Cell Biol 2007 1.95
14 Short-chain ubiquitination mediates the regulated endocytosis of the aquaporin-2 water channel. Proc Natl Acad Sci U S A 2006 1.91
15 The small chemical vacuolin-1 inhibits Ca(2+)-dependent lysosomal exocytosis but not cell resealing. EMBO Rep 2004 1.82
16 A viral protein that blocks Arf1-mediated COP-I assembly by inhibiting the guanine nucleotide exchange factor GBF1. Dev Cell 2006 1.77
17 Rab14 is involved in membrane trafficking between the Golgi complex and endosomes. Mol Biol Cell 2004 1.68
18 SNX1 defines an early endosomal recycling exit for sortilin and mannose 6-phosphate receptors. Traffic 2007 1.66
19 Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway. J Cell Biol 2004 1.65
20 Opinion: The maturing role of COPI vesicles in intra-Golgi transport. Nat Rev Mol Cell Biol 2005 1.55
21 Atg5-independent sequestration of ubiquitinated mycobacteria. PLoS Pathog 2009 1.55
22 mTrs130 is a component of a mammalian TRAPPII complex, a Rab1 GEF that binds to COPI-coated vesicles. Mol Biol Cell 2009 1.55
23 Immuno-electron tomography of ER exit sites reveals the existence of free COPII-coated transport carriers. Nat Cell Biol 2006 1.53
24 Sorting nexin 17 facilitates LRP recycling in the early endosome. EMBO J 2005 1.50
25 S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover. Am J Physiol Cell Physiol 2007 1.44
26 The somatodendritic endosomal regulator NEEP21 facilitates axonal targeting of L1/NgCAM. J Cell Biol 2008 1.42
27 Correlative light-electron microscopy (CLEM) combining live-cell imaging and immunolabeling of ultrathin cryosections. Nat Methods 2008 1.40
28 Rabaptin-5alpha/rabaptin-4 serves as a linker between rab4 and gamma(1)-adaptin in membrane recycling from endosomes. EMBO J 2003 1.39
29 Sorting nexin-2 is associated with tubular elements of the early endosome, but is not essential for retromer-mediated endosome-to-TGN transport. J Cell Sci 2005 1.38
30 Electron microscopy in cell biology: integrating structure and function. Nat Rev Mol Cell Biol 2003 1.33
31 Glycosylation is important for cell surface expression of the water channel aquaporin-2 but is not essential for tetramerization in the endoplasmic reticulum. J Biol Chem 2003 1.32
32 ATPase-deficient hVPS4 impairs formation of internal endosomal vesicles and stabilizes bilayered clathrin coats on endosomal vacuoles. J Cell Sci 2004 1.22
33 Imaging and imagination: understanding the endo-lysosomal system. Histochem Cell Biol 2008 1.21
34 Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes. PLoS Biol 2010 1.18
35 Death-receptor activation halts clathrin-dependent endocytosis. Proc Natl Acad Sci U S A 2006 1.18
36 Endosomes: multipurpose designs for integrating housekeeping and specialized tasks. Histochem Cell Biol 2001 1.15
37 hVps41 and VAMP7 function in direct TGN to late endosome transport of lysosomal membrane proteins. Nat Commun 2013 1.14
38 Egfl7 knockdown causes defects in the extension and junctional arrangements of endothelial cells during zebrafish vasculogenesis. Dev Dyn 2008 1.13
39 The RapGEF PDZ-GEF2 is required for maturation of cell-cell junctions. Cell Signal 2008 1.11
40 Involvement of a Golgi-resident GPI-anchored protein in maintenance of the Golgi structure. Mol Biol Cell 2007 1.09
41 Cripto recruits Furin and PACE4 and controls Nodal trafficking during proteolytic maturation. EMBO J 2008 1.09
42 Presenilin-1 exists in both pre- and post-Golgi compartments and recycles via COPI-coated membranes. Traffic 2003 1.08
43 The suppression of brain cold-stable microtubules in mice induces synaptic defects associated with neuroleptic-sensitive behavioral disorders. Genes Dev 2002 1.06
44 A flippase-independent function of ATP8B1, the protein affected in familial intrahepatic cholestasis type 1, is required for apical protein expression and microvillus formation in polarized epithelial cells. Hepatology 2010 1.03
45 Efficient IgM assembly and secretion require the plasma cell induced endoplasmic reticulum protein pERp1. Proc Natl Acad Sci U S A 2009 1.02
46 Associations among genotype, clinical phenotype, and intracellular localization of trafficking proteins in ARC syndrome. Hum Mutat 2012 1.00
47 The HOPS proteins hVps41 and hVps39 are required for homotypic and heterotypic late endosome fusion. Traffic 2012 0.98
48 Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling. Blood 2013 0.97
49 Vacuolization of mucolipidosis type II mouse exocrine gland cells represents accumulation of autolysosomes. Mol Biol Cell 2011 0.96
50 Intracellular activation of vasopressin V2 receptor mutants in nephrogenic diabetes insipidus by nonpeptide agonists. Proc Natl Acad Sci U S A 2009 0.96
51 A novel flat-embedding method to prepare ultrathin cryosections from cultured cells in their in situ orientation. J Histochem Cytochem 2002 0.96
52 Disruption of the Man-6-P targeting pathway in mice impairs osteoclast secretory lysosome biogenesis. Traffic 2011 0.94
53 Lysosomal membrane protein composition, acidic pH and sterol content are regulated via a light-dependent pathway in metazoan cells. Traffic 2011 0.93
54 Cripto localizes Nodal at the limiting membrane of early endosomes. Sci Signal 2008 0.91
55 The Sec7 guanine nucleotide exchange factor GBF1 regulates membrane recruitment of BIG1 and BIG2 guanine nucleotide exchange factors to the trans-Golgi network (TGN). J Biol Chem 2013 0.90
56 Spatial regulation of Golgi phosphatidylinositol-4-phosphate is required for enzyme localization and glycosylation fidelity. Traffic 2010 0.90
57 Sunitinib and SU11652 inhibit acid sphingomyelinase, destabilize lysosomes, and inhibit multidrug resistance. Mol Cancer Ther 2013 0.90
58 Rab4 function in membrane recycling from early endosomes depends on a membrane to cytoplasm cycle. J Biol Chem 2002 0.89
59 Glycolipid-dependent sorting of melanosomal from lysosomal membrane proteins by lumenal determinants. Traffic 2008 0.88
60 The role of Egfl7 in vascular morphogenesis. Novartis Found Symp 2007 0.87
61 Aberrant receptor-mediated endocytosis of Schistosoma mansoni glycoproteins on host lipoproteins. PLoS Med 2006 0.84
62 Rescue of a nephrogenic diabetes insipidus-causing vasopressin V2 receptor mutant by cell-penetrating peptides. J Biol Chem 2007 0.84
63 Anti-EGFL7 antibodies enhance stress-induced endothelial cell death and anti-VEGF efficacy. J Clin Invest 2013 0.84
64 Presenilin-1-mediated retention of APP derivatives in early biosynthetic compartments. Traffic 2006 0.83
65 Autophagy, an Achilles' heel AKTing against cancer? Autophagy 2009 0.83
66 A novel type of macrothrombocytopenia associated with a defect in α2,3-sialylation. Am J Pathol 2011 0.82
67 Identification of the ubiquitin ligase Triad1 as a regulator of endosomal transport. Biol Open 2012 0.81
68 AP-3 and Rabip4' coordinately regulate spatial distribution of lysosomes. PLoS One 2012 0.79
69 R-SNARE ykt6 resides in membrane-associated protease-resistant protein particles and modulates cell cycle progression when over-expressed. Biol Cell 2012 0.77