Published in J Med Chem on July 08, 2010
Crystal structure of the mobile metallo-β-lactamase AIM-1 from Pseudomonas aeruginosa: insights into antibiotic binding and the role of Gln157. Antimicrob Agents Chemother (2012) 0.94
Cross-class metallo-β-lactamase inhibition by bisthiazolidines reveals multiple binding modes. Proc Natl Acad Sci U S A (2016) 0.92
Biochemical, mechanistic, and spectroscopic characterization of metallo-β-lactamase VIM-2. Biochemistry (2014) 0.90
Comparison of Verona Integron-Borne Metallo-β-Lactamase (VIM) Variants Reveals Differences in Stability and Inhibition Profiles. Antimicrob Agents Chemother (2015) 0.90
New β-Lactamase Inhibitors in the Clinic. Infect Dis Clin North Am (2016) 0.89
Structural insights into the subclass B3 metallo-β-lactamase SMB-1 and the mode of inhibition by the common metallo-β-lactamase inhibitor mercaptoacetate. Antimicrob Agents Chemother (2012) 0.88
Molecular basis of NDM-1, a new antibiotic resistance determinant. PLoS One (2011) 0.88
Solution structures of the Bacillus cereus metallo-β-lactamase BcII and its complex with the broad spectrum inhibitor R-thiomandelic acid. Biochem J (2013) 0.86
An Update on the Status of Potent Inhibitors of Metallo-β-Lactamases. Sci Pharm (2013) 0.83
New β-phospholactam as a carbapenem transition state analog: Synthesis of a broad-spectrum inhibitor of metallo-β-lactamases. Bioorg Med Chem Lett (2013) 0.82
Conformational dynamics of metallo-β-lactamase CcrA during catalysis investigated by using DEER spectroscopy. J Biol Inorg Chem (2015) 0.79
Carbamylmethyl Mercaptoacetate Thioether: A Novel Scaffold for the Development of L1 Metallo-β-lactamase Inhibitors. ACS Med Chem Lett (2017) 0.77
Fragment-based inhibitor discovery against β-lactamase. Future Med Chem (2014) 0.76
An accurate risk score based on anthropometric, dietary, and lifestyle factors to predict the development of type 2 diabetes. Diabetes Care (2007) 4.14
Modified Mediterranean diet and survival: EPIC-elderly prospective cohort study. BMJ (2005) 3.48
Body size and breast cancer risk: findings from the European Prospective Investigation into Cancer And Nutrition (EPIC). Int J Cancer (2004) 2.96
Update of the standard numbering scheme for class B beta-lactamases. Antimicrob Agents Chemother (2004) 2.83
Dietary pattern, inflammation, and incidence of type 2 diabetes in women. Am J Clin Nutr (2005) 2.82
Genetic and functional confirmation of the causality of the DGAT1 K232A quantitative trait nucleotide in affecting milk yield and composition. Proc Natl Acad Sci U S A (2004) 2.72
Metallo-beta-lactamases as emerging resistance determinants in Gram-negative pathogens: open issues. Int J Antimicrob Agents (2007) 2.61
Fiber and magnesium intake and incidence of type 2 diabetes: a prospective study and meta-analysis. Arch Intern Med (2007) 2.47
On functional and structural heterogeneity of VIM-type metallo-beta-lactamases. J Antimicrob Chemother (2003) 2.47
The evaluation of the diet/disease relation in the EPIC study: considerations for the calibration and the disease models. Int J Epidemiol (2008) 2.11
Body mass index history and risk of type 2 diabetes: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study. Am J Clin Nutr (2006) 1.98
Treatment of health-care-associated infections caused by Gram-negative bacteria: a consensus statement. Lancet Infect Dis (2008) 1.96
Mechanistic studies of the inactivation of TEM-1 and P99 by NXL104, a novel non-beta-lactam beta-lactamase inhibitor. Antimicrob Agents Chemother (2010) 1.87
A metallo-beta-lactamase enzyme in action: crystal structures of the monozinc carbapenemase CphA and its complex with biapenem. J Mol Biol (2005) 1.78
Risk of hypertension among women in the EPIC-Potsdam Study: comparison of relative risk estimates for exploratory and hypothesis-oriented dietary patterns. Am J Epidemiol (2003) 1.76
Chromosome-encoded CTX-M-3 from Kluyvera ascorbata: a possible origin of plasmid-borne CTX-M-1-derived cefotaximases. Antimicrob Agents Chemother (2004) 1.76
Agreement of self-reported medical history: comparison of an in-person interview with a self-administered questionnaire. Eur J Epidemiol (2004) 1.63
No association of consumption of animal foods with risk of ovarian cancer. Cancer Epidemiol Biomarkers Prev (2007) 1.55
Methodological approaches to study dietary patterns in relation to risk of coronary heart disease and stroke. Br J Nutr (2006) 1.54
CAU-1, a subclass B3 metallo-beta-lactamase of low substrate affinity encoded by an ortholog present in the Caulobacter crescentus chromosome. Antimicrob Agents Chemother (2002) 1.52
Current challenges in antimicrobial chemotherapy: focus on ß-lactamase inhibition. Drugs (2010) 1.50
An approach to construct simplified measures of dietary patterns from exploratory factor analysis. Br J Nutr (2003) 1.43
Comparison of anthropometric characteristics in predicting the incidence of type 2 diabetes in the EPIC-Potsdam study. Diabetes Care (2006) 1.40
The 1.5-A structure of Chryseobacterium meningosepticum zinc beta-lactamase in complex with the inhibitor, D-captopril. J Biol Chem (2003) 1.35
Crystal structure of extended-spectrum beta-lactamase Toho-1: insights into the molecular mechanism for catalytic reaction and substrate specificity expansion. Biochemistry (2003) 1.34
Dietary patterns among older Europeans: the EPIC-Elderly study. Br J Nutr (2005) 1.33
Analysis of the importance of the metallo-beta-lactamase active site loop in substrate binding and catalysis. Chem Biol (2003) 1.32
Dietary patterns and survival of older Europeans: the EPIC-Elderly Study (European Prospective Investigation into Cancer and Nutrition). Public Health Nutr (2007) 1.28
Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols. Org Biomol Chem (2008) 1.26
Intake of fruits and vegetables and risk of cancer of the upper aero-digestive tract: the prospective EPIC-study. Cancer Causes Control (2006) 1.23
Food groups as predictors for short-term weight changes in men and women of the EPIC-Potsdam cohort. J Nutr (2002) 1.22
Kinetic properties of four plasmid-mediated AmpC beta-lactamases. Antimicrob Agents Chemother (2005) 1.21
Mutational analysis of the catalytic centre of the Citrobacter freundii AmpD N-acetylmuramyl-L-alanine amidase. Biochem J (2004) 1.17
Description of In116, the first blaCTX-M-2-containing complex class 1 integron found in Morganella morganii isolates from Buenos Aires, Argentina. J Antimicrob Chemother (2005) 1.17
Identification of a food pattern characterized by high-fiber and low-fat food choices associated with low prospective weight change in the EPIC-Potsdam cohort. J Nutr (2005) 1.17
Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. Antimicrob Agents Chemother (2010) 1.16
Biochemical and structural characterization of the subclass B1 metallo-β-lactamase VIM-4. Antimicrob Agents Chemother (2010) 1.16
The fate of the BlaI repressor during the induction of the Bacillus licheniformis BlaP beta-lactamase. Mol Microbiol (2002) 1.15
The structure of the dizinc subclass B2 metallo-beta-lactamase CphA reveals that the second inhibitory zinc ion binds in the histidine site. Antimicrob Agents Chemother (2009) 1.14
Substrate-activated zinc binding of metallo-beta -lactamases: physiological importance of mononuclear enzymes. J Biol Chem (2002) 1.13
NMR structure of Citrobacter freundii AmpD, comparison with bacteriophage T7 lysozyme and homology with PGRP domains. J Mol Biol (2003) 1.13
Structure of palmitoylated BET3: insights into TRAPP complex assembly and membrane localization. EMBO J (2005) 1.11
A homocysteine metabolism-related dietary pattern and the risk of coronary heart disease in two independent German study populations. J Nutr (2005) 1.10
Carbohydrate intake and incidence of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study. Br J Nutr (2007) 1.09
Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases. Biochemistry (2009) 1.08
Is it necessary to change the classification of {beta}-lactamases? J Antimicrob Chemother (2005) 1.07
OXA-198, an acquired carbapenem-hydrolyzing class D beta-lactamase from Pseudomonas aeruginosa. Antimicrob Agents Chemother (2011) 1.07
KCNJ11 E23K affects diabetes risk and is associated with the disposition index: results of two independent German cohorts. Diabetes Care (2007) 1.06
Crystal structure of the Bacillus subtilis penicillin-binding protein 4a, and its complex with a peptidoglycan mimetic peptide. J Mol Biol (2007) 1.06
From dormant to germinating spores of Streptomyces coelicolor A3(2): new perspectives from the crp null mutant. J Proteome Res (2005) 1.05
Postgenomic scan of metallo-beta-lactamase homologues in rhizobacteria: identification and characterization of BJP-1, a subclass B3 ortholog from Bradyrhizobium japonicum. Antimicrob Agents Chemother (2006) 1.05
The relation between dietary protein, calcium and bone health in women: results from the EPIC-Potsdam cohort. Ann Nutr Metab (2005) 1.05
Crystal structure of Homo sapiens protein hp14.5. Proteins (2004) 1.05
Three factors that modulate the activity of class D β-lactamases and interfere with the post-translational carboxylation of Lys70. Biochem J (2010) 1.03
Inhibitors of VIM-2 by screening pharmacologically active and click-chemistry compound libraries. Bioorg Med Chem (2009) 1.02
Protein expression, aggregation, and triggered release from polymersomes as artificial cell-like structures. Angew Chem Int Ed Engl (2012) 1.02
Characterization of the bifunctional glycosyltransferase/acyltransferase penicillin-binding protein 4 of Listeria monocytogenes. J Bacteriol (2006) 1.02
Identification of bla(IMP-22) in Pseudomonas spp. in urban wastewater and nosocomial environments: biochemical characterization of a new IMP metallo-enzyme variant and its genetic location. J Antimicrob Chemother (2009) 1.01
IND-6, a highly divergent IND-type metallo-beta-lactamase from Chryseobacterium indologenes strain 597 isolated in Burkina Faso. Antimicrob Agents Chemother (2009) 1.01
Biochemical and molecular characterization of three new variants of AmpC beta-lactamases from Morganella morganii. Antimicrob Agents Chemother (2006) 1.01
Portion size adds limited information on variance in food intake of participants in the EPIC-Potsdam study. J Nutr (2003) 1.01
Polyolefin matrixes with permanent antibacterial activity: preparation, antibacterial activity, and action mode of the active species. Biomacromolecules (2006) 1.00
Crystal structure of the sensor domain of the BlaR penicillin receptor from Bacillus licheniformis. Biochemistry (2003) 1.00
Crystal structure of the Actinomadura R39 DD-peptidase reveals new domains in penicillin-binding proteins. J Biol Chem (2005) 1.00
Mutational analysis of the two zinc-binding sites of the Bacillus cereus 569/H/9 metallo-beta-lactamase. Biochem J (2002) 1.00
X-ray structure of fumarylacetoacetate hydrolase family member Homo sapiens FLJ36880. Biol Chem (2004) 1.00
Evidence of an intramolecular interaction between the two domains of the BlaR1 penicillin receptor during the signal transduction. J Biol Chem (2004) 0.99
Mutational analysis of the zinc- and substrate-binding sites in the CphA metallo-beta-lactamase from Aeromonas hydrophila. Biochem J (2008) 0.99
Crystal structures of the Bacillus licheniformis BS3 class A beta-lactamase and of the acyl-enzyme adduct formed with cefoxitin. Biochemistry (2002) 0.98
Fruit and vegetable consumption and risk of epithelial ovarian cancer: the European Prospective Investigation into Cancer and Nutrition. Cancer Epidemiol Biomarkers Prev (2005) 0.98
Body mass index and C-174G interleukin-6 promoter polymorphism interact in predicting type 2 diabetes. J Clin Endocrinol Metab (2004) 0.97