Published in Microcirculation on May 01, 2010
How NaCl raises blood pressure: a new paradigm for the pathogenesis of salt-dependent hypertension. Am J Physiol Heart Circ Physiol (2011) 1.43
Pharmacological inhibition of TRPM4 hyperpolarizes vascular smooth muscle. Am J Physiol Cell Physiol (2010) 1.35
Clinical, cellular, and molecular aspects in the pathophysiology of rosacea. J Investig Dermatol Symp Proc (2011) 1.27
TRPV channels and vascular function. Acta Physiol (Oxf) (2010) 1.16
Emerging concepts for the role of TRP channels in the cardiovascular system. J Physiol (2010) 1.00
Mice lacking functional TRPV1 are protected from pressure overload cardiac hypertrophy. Channels (Austin) (2011) 0.94
Identification of L- and T-type Ca2+ channels in rat cerebral arteries: role in myogenic tone development. Am J Physiol Heart Circ Physiol (2012) 0.93
Molecular mechanisms of tumour invasion: regulation by calcium signals. J Physiol (2017) 0.84
Role of the monocyte chemoattractant protein-1/C-C chemokine receptor 2 signaling pathway in transient receptor potential vanilloid type 1 ablation-induced renal injury in salt-sensitive hypertension. Exp Biol Med (Maywood) (2015) 0.79
Functional TRPV and TRPM channels in human preadipocytes. Pflugers Arch (2013) 0.79
The effect of Shenmai injection on the proliferation of Rat airway smooth muscle cells in asthma and underlying mechanism. BMC Complement Altern Med (2013) 0.79
Regulation of cerebral artery smooth muscle membrane potential by Ca²⁺-activated cation channels. Microcirculation (2013) 0.78
Down-regulation of TRPM8 in pulmonary arteries of pulmonary hypertensive rats. Cell Physiol Biochem (2013) 0.77
Endothelial SK3 channel-associated Ca2+ microdomains modulate blood pressure. Am J Physiol Heart Circ Physiol (2016) 0.75
Redox Regulation of Transient Receptor Potential Channels in the Endothelium. Microcirculation (2016) 0.75
The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature (1997) 30.59
Relaxation of arterial smooth muscle by calcium sparks. Science (1995) 10.27
On the local reactions of the arterial wall to changes of internal pressure. J Physiol (1902) 9.36
Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature (2002) 8.94
A TRP channel that senses cold stimuli and menthol. Cell (2002) 8.66
Transient receptor potential cation channels in disease. Physiol Rev (2007) 6.91
A capsaicin-receptor homologue with a high threshold for noxious heat. Nature (1999) 5.85
Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors. Circ Res (1996) 5.77
The transient receptor potential protein homologue TRP6 is the essential component of vascular alpha(1)-adrenoceptor-activated Ca(2+)-permeable cation channel. Circ Res (2001) 5.04
ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology. Nature (2001) 4.75
Heat-evoked activation of the ion channel, TRPV4. J Neurosci (2002) 4.69
Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels. Nature (2003) 4.45
TRP-PLIK, a bifunctional protein with kinase and ion channel activities. Science (2001) 4.33
Regulation of arterial diameter and wall [Ca2+] in cerebral arteries of rat by membrane potential and intravascular pressure. J Physiol (1998) 4.16
Regulation of vertebrate cellular Mg2+ homeostasis by TRPM7. Cell (2003) 4.15
OSM-9, a novel protein with structural similarity to channels, is required for olfaction, mechanosensation, and olfactory adaptation in Caenorhabditis elegans. J Neurosci (1997) 4.06
Hypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the TRPM gene family. Nat Genet (2002) 3.90
OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity. Nat Cell Biol (2000) 3.88
A heat-sensitive TRP channel expressed in keratinocytes. Science (2002) 3.85
Molecular characterization of the Drosophila trp locus: a putative integral membrane protein required for phototransduction. Neuron (1989) 3.79
TRPV3 is a calcium-permeable temperature-sensitive cation channel. Nature (2002) 3.55
LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death. Mol Cell (2002) 3.36
TRPV3 is a temperature-sensitive vanilloid receptor-like protein. Nature (2002) 3.23
TRPV4 forms a novel Ca2+ signaling complex with ryanodine receptors and BKCa channels. Circ Res (2005) 3.22
TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorption. J Biol Chem (2003) 3.15
Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives. J Biol Chem (2002) 3.14
TRPM4 is a Ca2+-activated nonselective cation channel mediating cell membrane depolarization. Cell (2002) 3.13
Clues to understanding cold sensation: thermodynamics and electrophysiological analysis of the cold receptor TRPM8. Proc Natl Acad Sci U S A (2004) 3.11
CaT1 manifests the pore properties of the calcium-release-activated calcium channel. Nature (2001) 2.98
Transient receptor potential channels: targeting pain at the source. Nat Rev Drug Discov (2009) 2.88
Heat-evoked activation of TRPV4 channels in a HEK293 cell expression system and in native mouse aorta endothelial cells. J Biol Chem (2002) 2.87
Bimodal action of menthol on the transient receptor potential channel TRPA1. J Neurosci (2007) 2.78
Transient receptor potential M3 channels are ionotropic steroid receptors in pancreatic beta cells. Nat Cell Biol (2008) 2.71
2-aminoethoxydiphenyl borate is a common activator of TRPV1, TRPV2, and TRPV3. J Biol Chem (2004) 2.71
Genetic dissection of the Drosophila nervous system by means of mosaics. Proc Natl Acad Sci U S A (1970) 2.70
Mutation of TRPM6 causes familial hypomagnesemia with secondary hypocalcemia. Nat Genet (2002) 2.63
Transient receptor potential channels regulate myogenic tone of resistance arteries. Circ Res (2002) 2.59
Oregano, thyme and clove-derived flavors and skin sensitizers activate specific TRP channels. Nat Neurosci (2006) 2.58
Functional characterization of homo- and heteromeric channel kinases TRPM6 and TRPM7. J Gen Physiol (2006) 2.56
TRPC1, a human homolog of a Drosophila store-operated channel. Proc Natl Acad Sci U S A (1995) 2.56
Transient receptor potential vanilloid 4-mediated disruption of the alveolar septal barrier: a novel mechanism of acute lung injury. Circ Res (2006) 2.49
Critical role for transient receptor potential channel TRPM4 in myogenic constriction of cerebral arteries. Circ Res (2004) 2.47
TRPM5 is a voltage-modulated and Ca(2+)-activated monovalent selective cation channel. Curr Biol (2003) 2.45
Down-regulation of the novel gene melastatin correlates with potential for melanoma metastasis. Cancer Res (1998) 2.43
Modulation of the Ca2 permeable cation channel TRPV4 by cytochrome P450 epoxygenases in vascular endothelium. Circ Res (2005) 2.38
Homo- and heterotetrameric architecture of the epithelial Ca2+ channels TRPV5 and TRPV6. EMBO J (2003) 2.35
Protein kinase C regulates vascular myogenic tone through activation of TRPM4. Am J Physiol Heart Circ Physiol (2007) 2.35
Pressure-dependent membrane depolarization in cat middle cerebral artery. Circ Res (1984) 2.33
Physiology and pathophysiology of canonical transient receptor potential channels. FASEB J (2008) 2.31
A common mechanism underlies stretch activation and receptor activation of TRPC6 channels. Proc Natl Acad Sci U S A (2006) 2.30
2-aminoethoxydiphenyl borate activates and sensitizes the heat-gated ion channel TRPV3. J Neurosci (2004) 2.27
The Ca2+-activated cation channel TRPM4 is regulated by phosphatidylinositol 4,5-biphosphate. EMBO J (2006) 2.22
Voltage dependence of the Ca2+-activated cation channel TRPM4. J Biol Chem (2003) 2.21
Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia. Proc Natl Acad Sci U S A (2004) 2.17
Molecular cloning and characterization of a channel-like transporter mediating intestinal calcium absorption. J Biol Chem (1999) 2.16
Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channels. Mol Cell (2005) 2.15
TRPs in our senses. Curr Biol (2008) 2.12
TRPV2 is a component of osmotically sensitive cation channels in murine aortic myocytes. Circ Res (2003) 2.08
TRPM5 is a transient Ca2+-activated cation channel responding to rapid changes in [Ca2+]i. Proc Natl Acad Sci U S A (2003) 2.01
Evidence for a functional role of endothelial transient receptor potential V4 in shear stress-induced vasodilatation. Arterioscler Thromb Vasc Biol (2006) 1.99
Heteromultimeric TRPC6-TRPC7 channels contribute to arginine vasopressin-induced cation current of A7r5 vascular smooth muscle cells. Circ Res (2006) 1.99
Permeation and gating properties of the novel epithelial Ca(2+) channel. J Biol Chem (2000) 1.98
Systemic activation of the transient receptor potential vanilloid subtype 4 channel causes endothelial failure and circulatory collapse: Part 2. J Pharmacol Exp Ther (2008) 1.98
Molecular identification of the apical Ca2+ channel in 1, 25-dihydroxyvitamin D3-responsive epithelia. J Biol Chem (1999) 1.96
Phosphatidylinositol 4,5-bisphosphate rescues TRPM4 channels from desensitization. J Biol Chem (2005) 1.94
Mutants of the visual pathway of Drosophila melanogaster. Nature (1970) 1.91
Transient receptor potential melastatin 8 channel involvement in the regulation of vascular tone. Am J Physiol Heart Circ Physiol (2009) 1.85
Functional expression of transient receptor potential melastatin- and vanilloid-related channels in pulmonary arterial and aortic smooth muscle. Am J Physiol Lung Cell Mol Physiol (2006) 1.84
Regulation of the Ca2+ sensitivity of the nonselective cation channel TRPM4. J Biol Chem (2004) 1.82
Arterial response to shear stress critically depends on endothelial TRPV4 expression. PLoS One (2007) 1.79
TRPM1 forms ion channels associated with melanin content in melanocytes. Sci Signal (2009) 1.75
Block of TRPC5 channels by 2-aminoethoxydiphenyl borate: a differential, extracellular and voltage-dependent effect. Br J Pharmacol (2005) 1.72
Comparison of functional properties of the Ca2+-activated cation channels TRPM4 and TRPM5 from mice. Cell Calcium (2005) 1.70
Molecular and functional characterization of the melastatin-related cation channel TRPM3. J Biol Chem (2003) 1.69
TRPC3 mediates pyrimidine receptor-induced depolarization of cerebral arteries. Am J Physiol Heart Circ Physiol (2004) 1.68
A TRP homolog in Saccharomyces cerevisiae forms an intracellular Ca(2+)-permeable channel in the yeast vacuolar membrane. Proc Natl Acad Sci U S A (2001) 1.63
Endothelium-dependent cerebral artery dilation mediated by TRPA1 and Ca2+-Activated K+ channels. Circ Res (2009) 1.53
Alternative splicing switches the divalent cation selectivity of TRPM3 channels. J Biol Chem (2005) 1.52
Transient receptor potential vanilloid type 4-deficient mice exhibit impaired endothelium-dependent relaxation induced by acetylcholine in vitro and in vivo. Hypertension (2009) 1.51
Activation of the melastatin-related cation channel TRPM3 by D-erythro-sphingosine [corrected]. Mol Pharmacol (2004) 1.49
9-phenanthrol inhibits human TRPM4 but not TRPM5 cationic channels. Br J Pharmacol (2008) 1.48
TRPV4-dependent dilation of peripheral resistance arteries influences arterial pressure. Am J Physiol Heart Circ Physiol (2009) 1.47
PLA2 and TRPV4 channels regulate endothelial calcium in cerebral arteries. Am J Physiol Heart Circ Physiol (2006) 1.44
Function and expression of the epithelial Ca(2+) channel family: comparison of mammalian ECaC1 and 2. J Physiol (2001) 1.39
Transient receptor potential melastatin 7 ion channels regulate magnesium homeostasis in vascular smooth muscle cells: role of angiotensin II. Circ Res (2004) 1.36
Polyvalent cations as permeant probes of MIC and TRPM7 pores. Biophys J (2003) 1.36
Characterization of epoxyeicosatrienoic acid binding site in U937 membranes using a novel radiolabeled agonist, 20-125i-14,15-epoxyeicosa-8(Z)-enoic acid. J Pharmacol Exp Ther (2008) 1.35
Pharmacological differences between the human and rat vanilloid receptor 1 (VR1). Br J Pharmacol (2001) 1.35
Protein kinase C modulates basal myogenic tone in resistance arteries from the cerebral circulation. Circ Res (1991) 1.31
Inhibition of the transient receptor potential cation channel TRPM2 by 2-aminoethoxydiphenyl borate (2-APB). Br J Pharmacol (2008) 1.30
Intracellular nucleotides and polyamines inhibit the Ca2+-activated cation channel TRPM4b. Pflugers Arch (2004) 1.27
Differential expression and alternative splicing of TRP channel genes in smooth muscles. Am J Physiol Cell Physiol (2001) 1.25
Cytochrome p-450 epoxygenase products contribute to attenuated vasoconstriction after chronic hypoxia. Am J Physiol Heart Circ Physiol (2003) 1.22
Central role of TRPM4 channels in cerebral blood flow regulation. Stroke (2007) 1.21
Transient receptor potential melastatin 6 and 7 channels, magnesium transport, and vascular biology: implications in hypertension. Am J Physiol Heart Circ Physiol (2008) 1.19
Membrane stretch-induced activation of a TRPM4-like nonselective cation channel in cerebral artery myocytes. J Pharmacol Sci (2007) 1.15
Tissue-specific regulation of microvascular diameter: opposite functional roles of neuronal and smooth muscle located vanilloid receptor-1. Mol Pharmacol (2008) 1.15
Inhibition of TRPM2 channels by the antifungal agents clotrimazole and econazole. Naunyn Schmiedebergs Arch Pharmacol (2004) 1.15
Evidence for protein kinase C involvement in arteriolar myogenic reactivity. Am J Physiol (1990) 1.11
Endothelium-dependent cerebral artery dilation mediated by transient receptor potential and Ca2+-activated K+ channels. J Cardiovasc Pharmacol (2011) 0.96
(Sub)family feud: crosstalk between TRPC channels in vascular smooth muscle cells during vasoconstrictor agonist stimulation. J Physiol (2010) 0.75