PubRank

J L Carpentier

Author PubWeight™ 114.98‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Epidermal growth factor: morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts. Proc Natl Acad Sci U S A 1978 4.03
2 Ligands internalized through coated or noncoated invaginations follow a common intracellular pathway. Proc Natl Acad Sci U S A 1987 3.33
3 Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes. Cell 1999 2.89
4 The osmotic integrity of the yeast cell requires a functional PKC1 gene product. Mol Cell Biol 1992 2.78
5 125I-insulin binding to cultured human lymphocytes. Initial localization and fate of hormone determined by quantitative electron microscopic autoradiography. J Clin Invest 1978 2.47
6 The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes. J Cell Biol 1990 2.36
7 Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes. EMBO J 1998 2.25
8 Occurrence of low density lipoprotein receptors within large pits on the surface of human fibroblasts as demonstrated by freeze-etching. Exp Cell Res 1978 2.15
9 Co-localization of 125I-epidermal growth factor and ferritin-low density lipoprotein in coated pits: a quantitative electron microscopic study in normal and mutant human fibroblasts. J Cell Biol 1982 1.88
10 Cytosolic free calcium elevation mediates the phagosome-lysosome fusion during phagocytosis in human neutrophils. J Cell Biol 1990 1.85
11 The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane. Immunity 1997 1.78
12 Intracellular translocation of iodine-125-labeled insulin: direct demonstration in isolated hepatocytes. Science 1978 1.66
13 Internalized insulin receptors are recycled to the cell surface in rat hepatocytes. Proc Natl Acad Sci U S A 1982 1.63
14 Lysosomal association of internalized 125I-insulin in isolated rat hepatocytes. Direct demonstration by quantitative electron microscopic autoradiography. J Clin Invest 1979 1.63
15 Co-regulation of the mitogen-activated protein kinase, extracellular signal-regulated kinase 1, and the 90-kDa ribosomal S6 kinase in PC12 cells. Distinct effects of the neurotrophic factor, nerve growth factor, and the mitogenic factor, epidermal growth factor. J Biol Chem 1993 1.61
16 Internalization of polypeptide hormones: mechanism, intracellular localization and significance. Diabetologia 1980 1.49
17 Glucagon secretion in diabetic patients with idiopathic haemochromatosis. Diabetologia 1977 1.42
18 Redistribution of intracellular Ca2+ stores during phagocytosis in human neutrophils. Science 1994 1.39
19 Cloning and functional characterization of mammalian homologues of the COPII component Sec23. Mol Biol Cell 1996 1.39
20 Nef-mediated clathrin-coated pit formation. J Cell Biol 1997 1.38
21 CD14-dependent endotoxin internalization via a macropinocytic pathway. J Biol Chem 1998 1.33
22 Morphological changes of the 3T3-L1 fibroblast plasma membrane upon differentiation to the adipocyte form. J Cell Sci 1983 1.32
23 Binding and internalization of 125I-LDL in normal and mutant human fibroblasts. A quantitative autoradiographic study. Exp Cell Res 1979 1.32
24 Receptor-mediated endocytosis of insulin: role of microvilli, coated pits, and coated vesicles. Proc Natl Acad Sci U S A 1982 1.30
25 Sec24 proteins and sorting at the endoplasmic reticulum. J Biol Chem 1999 1.30
26 Surface redistribution of 125I-insulin in cultured human lymphocytes. J Cell Biol 1981 1.27
27 Biochemical and morphological evidence that the insulin receptor is internalized with insulin in hepatocytes. J Cell Biol 1982 1.27
28 Intracellular potassium depletion in IM-9 lymphocytes suppresses the slowly dissociating component of human growth hormone binding and the down-regulation of its receptors but does not affect insulin receptors. Proc Natl Acad Sci U S A 1986 1.15
29 Subcellular distribution of the external and internal domains of the EGF receptor in A-431 cells. Exp Cell Res 1986 1.15
30 Polypeptide hormone degradation and receptor regulation are coupled to ligand internalization. A direct biochemical and morphologic demonstration. J Biol Chem 1981 1.12
31 Pancreatic polypeptide: a possible role in the regulation of food intake in the mouse. Hypothesis. Experientia 1977 1.10
32 Intracellular localization of 125I-labeled insulin in hepatocytes from intact rat liver. Proc Natl Acad Sci U S A 1979 1.09
33 Identification of membrane-bound CR1 (CD35) in human urine: evidence for its release by glomerular podocytes. J Exp Med 1994 1.08
34 Role of intracellular calcium and protein kinase C in the endocytosis of transferrin and insulin by HL60 cells. J Cell Biol 1986 1.06
35 Direct evidence for the clustered nature of complement receptors type 1 on the erythrocyte membrane. J Immunol 1988 1.06
36 Dual role of a dileucine motif in insulin receptor endocytosis. J Biol Chem 1997 1.03
37 Receptor mediated endocytosis of polypeptide hormones: mechanism and significance. Metabolism 1982 1.03
38 Binding, internalization, and lysosomal association of 125I-human growth hormone in cultured human lymphocytes: a quantitative morphological and biochemical study. J Cell Biol 1980 1.02
39 Redistribution of 125I-insulin on the surface of rat hepatocytes as a function of dissociation time. Diabetes 1985 0.98
40 [Interaction of epidermal growth factor with human fibroblasts in culture: an autoradiographic study at the ultrastructural level]. C R Acad Sci Hebd Seances Acad Sci D 1978 0.97
41 Cyclic AMP increases cell surface expression of functional Na,K-ATPase units in mammalian cortical collecting duct principal cells. Mol Biol Cell 2001 0.96
42 Difference in the clustering of complement receptor type 1 (CR1) on polymorphonuclear leukocytes and erythrocytes: effect on immune adherence. Eur J Immunol 1990 0.94
43 Down-regulation and recycling of insulin receptors. Effect of monensin on IM-9 lymphocytes and U-937 monocyte-like cells. J Biol Chem 1984 0.94
44 Clathrin-coated pit-mediated receptor internalization. Role of internalization signals and receptor mobility. J Biol Chem 1993 0.92
45 The fate of [125I]iodoepidermal growth factor in isolated hepatocytes: a quantitative electron microscopic autoradiographic study. Endocrinology 1981 0.90
46 Insulin receptors and bioresponses in a human liver cell line (Hep G-2). Eur J Biochem 1985 0.90
47 Internalization of the human insulin receptor. The insulin-independent pathway. J Biol Chem 1992 0.90
48 Intracellular pathway followed by the insulin receptor covalently coupled to 125I-photoreactive insulin during internalization and recycling. J Cell Biol 1986 0.88
49 Direct demonstration of insulin receptor internalization. A quantitative electron microscopic study of covalently bound 125I-photoreactive insulin incubated with isolated hepatocytes. Diabetes 1982 0.88
50 Specific glycosylation site mutations of the insulin receptor alpha subunit impair intracellular transport. Biochemistry 1993 0.88
51 Binding, internalization, and lysosomal association of 125I-glucagon in isolated rat hepatocytes. A quantitative electron microscope autoradiographic study. J Clin Invest 1980 0.88
52 Rabbit sciatic nerve fascicle and 'endoneurial' preparations for in vitro studies of peripheral nerve glucose metabolism. J Neurochem 1979 0.88
53 Direct demonstration of the endocytic function of caveolae by a cell-free assay. J Cell Sci 1999 0.87
54 Second-messenger regulation of receptor association with clathrin-coated pits: a novel and selective mechanism in the control of CD4 endocytosis. Mol Biol Cell 1997 0.86
55 Insulin-induced receptor loss in the cultured human lymphocyte: quantitative morphological perturbations in the cell and plasma membrane. J Cell Sci 1979 0.86
56 Insulin increases the Na(+)-K(+)-ATPase alpha 2-subunit in the surface of rat skeletal muscle: morphological evidence. Am J Physiol 1993 0.85
57 Processing and release of insulin and insulin-like growth factor I by macro- and microvascular endothelial cells. Endocrinology 1986 0.84
58 Persistent infection with a nontransforming RNA virus leads to impaired growth factor receptors and response. J Cell Physiol 1986 0.84
59 The functions of the human insulin receptor are affected in different ways by mutation of each of the four N-glycosylation sites in the beta subunit. J Biol Chem 1994 0.84
60 Polar redistribution of 125I-labelled insulin on the plasma membrane of cultured human lymphocytes. Nature 1980 0.83
61 An alteration in internodal myelin membrane structure in large sciatic nerve fibres in rats with acute streptozotocin diabetes and impaired nerve conduction velocity. Diabetologia 1978 0.83
62 Biosynthesis and regulation of the insulin receptor. Yale J Biol Med 1990 0.83
63 Internalization of 3H-glibenclamide in pancreatic islet cells. Diabetologia 1986 0.83
64 The HIV Nef protein alters Ca(2+) signaling in myelomonocytic cells through SH3-mediated protein-protein interactions. J Biol Chem 1999 0.82
65 Vitamin B 12 and folic acid serum levels in diabetics under various therapeutic regimens. Diabete Metab 1976 0.82
66 Quantitative evaluation of gap junctions during development of the brown adipose tissue. J Lipid Res 1980 0.81
67 The interaction of 125I-insulin with cultured 3T3-L1 adipocytes: quantitative analysis by the hypothetical grain method. J Histochem Cytochem 1983 0.81
68 Cys860 in the extracellular domain of insulin receptor beta-subunit is critical for internalization and signal transduction. Endocrinology 1998 0.80
69 Effect of pH and lysosomotropic agents on membrane-associated and internalized 125I-iodinated human growth hormone in cultured human lymphocytes: a quantitative biochemical and electron microscopic study. Endocrinology 1982 0.80
70 Insulin-induced translocation of Na+-K+-ATPase subunits to the plasma membrane is muscle fiber type specific. Am J Physiol 1996 0.80
71 Binding, membrane redistribution, internalization and lysosomal association of [125I]anti-insulin receptor antibody in IM-9-cultured human lymphocyte. A comparison with [125I]insulin. Exp Cell Res 1981 0.80
72 Endocytosis is inhibited in hepatocytes from diabetic rats. Diabetes 1993 0.80
73 Human circulating monocytes internalize 125I-insulin in a similar fashion to rat hepatocytes: relevance to receptor regulation in target and nontarget tissues. J Lab Clin Med 1985 0.80
74 Insulin action at the cellular level: anatomical considerations. Diabetes Metab Rev 1985 0.80
75 Perturbation of the adipose cell plasma membrane in obese (ob/ob) mice. Lab Invest 1977 0.80
76 The relationship of ligand receptor mobility to internalization of polypeptide hormones and growth factors. Endocrinology 1991 0.79
77 Effects of insulin, glucagon, and epinephrine on the plasma membrane of the white adipose cell: a freeze-fracture study. J Lipid Res 1976 0.79
78 Glucagon release from rat pancreatic islets. A combined morphological and functional approach. J Clin Invest 1977 0.79
79 Relationship of binding to internatlization of 125I-insulin in isolated rat hepatocytes. Diabetologia 1979 0.79
80 Internalization of polypeptide hormones and receptor recycling. Experientia 1986 0.79
81 The endosomal compartment of rat hepatocytes. Its characterization in the course of [125I]insulin internalization. Exp Cell Res 1985 0.79
82 Glucagon degradation in isolated rat hepatocytes: effect of ammonium chloride and chloroquine. Mol Cell Endocrinol 1981 0.79
83 Comparative studies on insulin-like growth factor II and insulin processing by vascular endothelial cells. Diabetes 1986 0.79
84 [Ultrastructural changes in the organization of plasma membranes in adipocytes of obese mice (ob/ob)]. C R Acad Sci Hebd Seances Acad Sci D 1976 0.78
85 CD4 in nonlymphocytic cells: more than an HIV receptor? J Lab Clin Med 1995 0.78
86 Role of the transmembrane domain and flanking amino acids in internalization and down-regulation of the insulin receptor. J Biol Chem 1995 0.78
87 Analysis of the juxtamembrane dileucine motif in the insulin receptor. Endocrinology 1998 0.78
88 Effect of hypertonicity and monensin on CD3/TCR surface expression in human T cells. Immunol Lett 1988 0.78
89 125I-Insulin is preferentially internalized in regions of the hepatocytes rich in lysosomal and Golgi structures. Experientia 1979 0.78
90 Soluble form of complement C3b/C4b receptor (CR1) results from a proteolytic cleavage in the C-terminal region of CR1 transmembrane domain. Biochem J 1998 0.78
91 Detection of surface-bound ligands by freeze-fracture autoradiography. J Cell Biol 1985 0.77
92 Insulin receptor internalization and recycling: mechanism and significance. Biochimie 1986 0.77
93 Morphologic probes of polypeptide hormone receptor interactions. J Histochem Cytochem 1980 0.77
94 Surface interactions and intracellular localization of cationic ferritin: similarity to 125I-insulin in 3T3-L1 adipocytes. Eur J Cell Biol 1983 0.77
95 Internalization and recycling of 125I-photoreactive insulin-receptor complexes in hepatocytes in primary culture. Mol Cell Endocrinol 1986 0.77
96 Receptor-mediated endocytosis of polypeptide hormones is a regulated process: inhibition of [125I]iodoinsulin internalization in hypoinsulinemic diabetes of rat and man. J Clin Endocrinol Metab 1986 0.77
97 Quantitative evaluation of gap junctions in rat brown adipose tissue after cold acclimation. J Membr Biol 1984 0.76
98 Transmembrane domain inversion blocks ER release and insulin receptor signaling. Biochemistry 1995 0.76
99 Down-regulation of insulin receptors is related to insulin internalization. Exp Cell Res 1989 0.76
100 Direct measurement of clathrin-coated vesicle formation using a cell-free assay. J Cell Sci 1997 0.76
101 Epidermal growth factor receptor internalization and biosynthesis in the diabetic rat. Exp Cell Res 1992 0.76
102 Receptor-linked degradation of 125I-insulin is mediated by internalization in isolated rat hepatocytes. Yale J Biol Med 1982 0.75
103 Receptor binding and internalization of biosynthetic human insulin in isolated rat hepatocytes. Mol Cell Endocrinol 1983 0.75
104 Receptor-mediated endocytosis of polypeptide hormones. Acta Histochem Suppl 1984 0.75
105 Receptor-mediated endocytosis of insulin: inhibition of [125I]iodoinsulin internalization in insulin resistant diabetic states of man. Acta Endocrinol (Copenh) 1989 0.75
106 Cytological and ultrastructural study of the lymphoid-like and X cell populations in mouse bone marrow during the neonatal period. Exp Hematol 1975 0.75
107 125I-anti-insulin receptor Fab is internalized by cultured human lymphocytes. Biochem Biophys Res Commun 1983 0.75
108 The N-formyl methionyl peptide, formyl-methionyl-leucyl phenylalanine (fMLF) increases the lateral diffusion of complement receptor 1 (CR1/CD35) in human neutrophils; a causative role for oxidative metabolites? Biosci Rep 1996 0.75
109 [Morphological aspects of the interaction of insulin with its target cell]. Journ Annu Diabetol Hotel Dieu 1980 0.75
110 Insulin receptor tyrosine kinase activity is abnormal in circulating cells and cultured fibroblasts but normal in transformed lymphocytes from a type A insulin-resistant patient. J Lab Clin Med 1988 0.75
111 Exudation induces clustering of CR1 receptors at the surface of human polymorphonuclear leukocytes. Biochem Biophys Res Commun 1990 0.75
112 Receptor-mediated endocytosis of polypeptide hormones: mechanism and significance. Mol Immunol 1984 0.75
113 Epidermal growth factor secretion by submandibular glands is not perturbed in the early phase of streptozotocin-induced diabetes in mice. Histochemistry 1994 0.75
114 Cell surface alteration in Epstein-Barr virus-transformed cells from patients with extreme insulin resistance. Diabetes 1990 0.75
115 Internalization of polypeptide hormones and receptor recycling. Experientia Suppl 1987 0.75
116 Ultrastructural demonstration of peculair lymphoid cells in the thymus during the perinatal period in mice, Correlation with radioleukemogenesis. Eur J Cancer 1975 0.75
117 Diacylglycerol modulation of insulin receptor from cultured human mononuclear cells. Effects on binding and internalization. Diabetes 1986 0.75
118 Internalization of 125I-insulin by IM-9 cultured human lymphocytes: a comparison between A14-monoiodo-pork and biosynthetic human insulin. Diabetes Care 1981 0.75