Published in Exp Biol Med (Maywood) on June 11, 2010
The supposed tumor suppressor gene WWOX is mutated in an early lethal microcephaly syndrome with epilepsy, growth retardation and retinal degeneration. Orphanet J Rare Dis (2014) 1.23
LITAF and TNFSF15, two downstream targets of AMPK, exert inhibitory effects on tumor growth. Oncogene (2011) 1.03
Trafficking protein particle complex 6A delta (TRAPPC6AΔ) is an extracellular plaque-forming protein in the brain. Oncotarget (2015) 0.98
Drosophila orthologue of WWOX, the chromosomal fragile site FRA16D tumour suppressor gene, functions in aerobic metabolism and regulates reactive oxygen species. Hum Mol Genet (2010) 0.98
Zfra is a small wizard in the mitochondrial apoptosis. Aging (Albany NY) (2010) 0.97
WW domain-containing oxidoreductase in neuronal injury and neurological diseases. Oncotarget (2014) 0.96
Identification of an In Vivo MEK/WOX1 Complex as a Master Switch for Apoptosis in T Cell Leukemia. Genes Cancer (2011) 0.96
Zfra activates memory Hyal-2+ CD3- CD19- spleen cells to block cancer growth, stemness, and metastasis in vivo. Oncotarget (2015) 0.89
The fragile site WWOX gene and the developing brain. Exp Biol Med (Maywood) (2014) 0.88
TIAF1 self-aggregation in peritumor capsule formation, spontaneous activation of SMAD-responsive promoter in p53-deficient environment, and cell death. Cell Death Dis (2012) 0.88
Emerging roles for hyaluronidase in cancer metastasis and therapy. Adv Cancer Res (2014) 0.87
Tumor Suppressor WWOX and p53 Alterations and Drug Resistance in Glioblastomas. Front Oncol (2013) 0.86
HGF and TGFβ1 differently influenced Wwox regulatory function on Twist program for mesenchymal-epithelial transition in bone metastatic versus parental breast carcinoma cells. Mol Cancer (2015) 0.80
WWOX dysfunction induces sequential aggregation of TRAPPC6AΔ, TIAF1, tau and amyloid β, and causes apoptosis. Cell Death Discov (2015) 0.80
Role of WWOX and NF-κB in lung cancer progression. Transl Respir Med (2013) 0.79
Functions and Epigenetic Regulation of Wwox in Bone Metastasis from Breast Carcinoma: Comparison with Primary Tumors. Int J Mol Sci (2017) 0.78
Tumor Suppressor WWOX Contributes to the Elimination of Tumorigenic Cells in Drosophila melanogaster. PLoS One (2015) 0.78
Strategies of oncogenic microbes to deal with WW domain-containing oxidoreductase. Exp Biol Med (Maywood) (2014) 0.77
HYAL-2-WWOX-SMAD4 Signaling in Cell Death and Anticancer Response. Front Cell Dev Biol (2016) 0.76
Role of WW Domain-containing Oxidoreductase WWOX in Driving T Cell Acute Lymphoblastic Leukemia Maturation. J Biol Chem (2016) 0.76
Zfra induction of memory anticancer response via a novel immune cell. Oncoimmunology (2016) 0.75
Hyaluronan activates Hyal-2/WWOX/Smad4 signaling and causes bubbling cell death when the signaling complex is overexpressed. Oncotarget (2016) 0.75
Role of WW domain proteins WWOX in development, prognosis, and treatment response of glioma. Exp Biol Med (Maywood) (2014) 0.75
Lung cancer in China: challenges and interventions. Chest (2013) 2.31
WW domain-containing oxidoreductase: a candidate tumor suppressor. Trends Mol Med (2006) 1.44
WOX1 is essential for tumor necrosis factor-, UV light-, staurosporine-, and p53-mediated cell death, and its tyrosine 33-phosphorylated form binds and stabilizes serine 46-phosphorylated p53. J Biol Chem (2005) 1.40
Down-regulation of WW domain-containing oxidoreductase induces Tau phosphorylation in vitro. A potential role in Alzheimer's disease. J Biol Chem (2004) 1.31
Transforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1. J Biol Chem (2009) 1.28
Zfra affects TNF-mediated cell death by interacting with death domain protein TRADD and negatively regulates the activation of NF-kappaB, JNK1, p53 and WOX1 during stress response. BMC Mol Biol (2007) 1.26
Gold nanorods in photodynamic therapy, as hyperthermia agents, and in near-infrared optical imaging. Angew Chem Int Ed Engl (2010) 1.22
17beta-Estradiol upregulates and activates WOX1/WWOXv1 and WOX2/WWOXv2 in vitro: potential role in cancerous progression of breast and prostate to a premetastatic state in vivo. Oncogene (2005) 1.18
Sequential caspase-2 and caspase-8 activation upstream of mitochondria during ceramideand etoposide-induced apoptosis. J Biol Chem (2004) 1.15
WOX1 is essential for UVB irradiation-induced apoptosis and down-regulated via translational blockade in UVB-induced cutaneous squamous cell carcinoma in vivo. Clin Cancer Res (2005) 1.14
Microfluidic systems integrated with two-dimensional surface plasmon resonance phase imaging systems for microarray immunoassay. Biosens Bioelectron (2007) 1.11
MPP+-induced neuronal death in rats involves tyrosine 33 phosphorylation of WW domain-containing oxidoreductase WOX1. Eur J Neurosci (2008) 1.08
Spatiotemporal focusing-based widefield multiphoton microscopy for fast optical sectioning. Opt Express (2012) 1.07
Complement C1q activates tumor suppressor WWOX to induce apoptosis in prostate cancer cells. PLoS One (2009) 1.05
Fast multiphoton microfabrication of freeform polymer microstructures by spatiotemporal focusing and patterned excitation. Opt Express (2012) 1.02
Zfra is an inhibitor of Bcl-2 expression and cytochrome c release from the mitochondria. Cell Signal (2008) 0.98
Dramatic co-activation of WWOX/WOX1 with CREB and NF-kappaB in delayed loss of small dorsal root ganglion neurons upon sciatic nerve transection in rats. PLoS One (2009) 0.98
Zfra is a small wizard in the mitochondrial apoptosis. Aging (Albany NY) (2010) 0.97
Kinetic analysis of beta-amyloid peptide aggregation induced by metal ions based on surface plasmon resonance biosensing. J Neurosci Methods (2006) 0.97
Different types of exercise induce differential effects on neuronal adaptations and memory performance. Neurobiol Learn Mem (2011) 0.97
Effect of continuous hemofiltration on hemodynamics, lung inflammation and pulmonary edema in a canine model of acute lung injury. Intensive Care Med (2003) 0.97
Identification of an In Vivo MEK/WOX1 Complex as a Master Switch for Apoptosis in T Cell Leukemia. Genes Cancer (2011) 0.96
Gold nanomaterials conjugated with indocyanine green for dual-modality photodynamic and photothermal therapy. Biomaterials (2012) 0.95
Dynamics of femtosecond laser photo-modification of collagen fibers. Opt Express (2008) 0.91
Cloning and characterization of a small-size peptide Zfra that regulates the cytotoxic function of tumor necrosis factor by interacting with JNK1. Biochem Biophys Res Commun (2005) 0.90
Discrimination of collagen in normal and pathological skin dermis through second-order susceptibility microscopy. Opt Express (2009) 0.89
Bcl-2 rescues ceramide- and etoposide-induced mitochondrial apoptosis through blockage of caspase-2 activation. J Biol Chem (2005) 0.88
TIAF1 participates in the transforming growth factor beta1--mediated growth regulation. Ann N Y Acad Sci (2003) 0.88
Analysis of collagen fiber domain organization by Fourier second harmonic generation microscopy. J Biomed Opt (2013) 0.88
TIAF1 and p53 functionally interact in mediating apoptosis and silencing of TIAF1 abolishes nuclear translocation of serine 15-phosphorylated p53. DNA Cell Biol (2004) 0.88
Laser-treated substrate with nanoparticles for surface-enhanced Raman scattering. Opt Lett (2010) 0.87
Prc contributes to Escherichia coli evasion of classical complement-mediated serum killing. Infect Immun (2012) 0.87
WWOX suppresses prostate cancer cell progression through cyclin D1-mediated cell cycle arrest in the G1 phase. Cell Cycle (2015) 0.87
High expression of TIAF-1 in chronic kidney and liver allograft rejection and in activated T-helper cells. Transplantation (2003) 0.87
Fast Fourier transform-based analysis of second-harmonic generation image in keratoconic cornea. Invest Ophthalmol Vis Sci (2012) 0.86
One-step fabrication of nanostructures by femtosecond laser for surface-enhanced Raman scattering. Opt Express (2009) 0.86
The use of mutation-specific antibodies in predicting the effect of EGFR-TKIs in patients with non-small-cell lung cancer. J Cancer Res Clin Oncol (2014) 0.86
Benzyl butyl phthalate induces migration, invasion, and angiogenesis of Huh7 hepatocellular carcinoma cells through nongenomic AhR/G-protein signaling. BMC Cancer (2014) 0.86
Tumor Suppressor WWOX and p53 Alterations and Drug Resistance in Glioblastomas. Front Oncol (2013) 0.86
Precise, motion-free polarization control in Second Harmonic Generation microscopy using a liquid crystal modulator in the infinity space. Biomed Opt Express (2013) 0.86
Overexpression of WW domain-containing oxidoreductase WOX1 preferentially induces apoptosis in human glioblastoma cells harboring mutant p53. Biomed Pharmacother (2012) 0.85
Innovative antimicrobial susceptibility testing method using surface plasmon resonance. Biosens Bioelectron (2008) 0.85
Assessing current therapeutic approaches to decode potential resistance mechanisms in glioblastomas. Front Oncol (2013) 0.85
Cell Adhesion on Micro-Structured Fibronectin Gradients Fabricated by Multiphoton Excited Photochemistry. Cell Mol Bioeng (2012) 0.84
"Arrow" sign: a rapid microscopic diagnosis of hair change associated with epidermal growth factor receptor inhibitors. J Am Acad Dermatol (2013) 0.84
CCAAT/enhancer binding protein δ in macrophages contributes to immunosuppression and inhibits phagocytosis in nasopharyngeal carcinoma. Sci Signal (2013) 0.84
High-throughput fabrication of gray-level biomicrostructures via temporal focusing excitation and laser pulse control. J Biomed Opt (2013) 0.84
Elucidation of the mechanisms of optical clearing in collagen tissue with multiphoton imaging. J Biomed Opt (2013) 0.84
Inhibition of TDP-43 aggregation by nucleic acid binding. PLoS One (2013) 0.83
Photophysical mechanisms of collagen modification by 80 MHz femtosecond laser. Opt Express (2010) 0.83
Optimizing silver film for surface plasmon-coupled emission induced two-photon excited fluorescence imaging. Opt Express (2011) 0.83
Nitrogen-doped graphene oxide quantum dots as photocatalysts for overall water-splitting under visible light illumination. Adv Mater (2014) 0.83
Solanum incanum extract (SR-T100) induces human cutaneous squamous cell carcinoma apoptosis through modulating tumor necrosis factor receptor signaling pathway. J Dermatol Sci (2011) 0.82
Temporal focusing-based multiphoton excitation microscopy via digital micromirror device. Opt Lett (2014) 0.82
Image-inspired 3D multiphoton excited fabrication of extracellular matrix structures by modulated raster scanning. Opt Express (2013) 0.82
Multiphoton spectral microscopy for imaging and quantification of tissue glycation. Biomed Opt Express (2010) 0.82
Enhanced live cell membrane imaging using surface plasmon-enhanced total internal reflection fluorescence microscopy. Opt Express (2006) 0.82
Protective role of autophagy in branched polyethylenimine (25K)- and poly(L-lysine) (30-70K)-induced cell death. Eur J Pharm Sci (2012) 0.82
Multimodal, multiphoton microscopy and image correlation analysis for characterizing corneal thermal damage. J Biomed Opt (2009) 0.81
Surface plasmon-enhanced two-photon fluorescence microscopy for live cell membrane imaging. Opt Express (2009) 0.81
Spatial and temporal analysis of skin glycation by the use of multiphoton microscopy and spectroscopy. J Dermatol Sci (2011) 0.81
Enhanced two-photon excited fluorescence in three-dimensionally crosslinked bovine serum albumin microstructures. Opt Express (2011) 0.81
Study of cell-biosubstrate contacts via surface plasmon polariton phase microscopy. Opt Express (2010) 0.81
Fabry-Perot interferometer embedded in a glass chip fabricated by femtosecond laser. Opt Lett (2009) 0.80
Optical waveguide biosensors constructed with subwavelength gratings. Appl Opt (2006) 0.80
Surface plasmon-enhanced and quenched two-photon excited fluorescence. Opt Express (2010) 0.80
Multiphoton fabrication of freeform polymer microstructures with gold nanorods. Opt Express (2010) 0.80
Chronic treadmill running in normotensive rats resets the resting blood pressure to lower levels by upregulating the hypothalamic GABAergic system. J Hypertens (2011) 0.80
WW domain-containing oxidoreductase is involved in upregulation of matrix metalloproteinase 9 by Epstein-Barr virus latent membrane protein 2A. Biochem Biophys Res Commun (2013) 0.80
Characterizing the morphologic changes in collagen crosslinked-treated corneas by Fourier transform-second harmonic generation imaging. J Cataract Refract Surg (2013) 0.80
Chronic treadmill exercise in rats delicately alters the Purkinje cell structure to improve motor performance and toxin resistance in the cerebellum. J Appl Physiol (1985) (2012) 0.79
Conformationally altered hyaluronan restricts complement classical pathway activation by binding to C1q, C1r, C1s, C2, C5 and C9, and suppresses WOX1 expression in prostate DU145 cells. Int J Mol Med (2007) 0.79
Quantitative analysis of multiphoton excitation autofluorescence and second harmonic generation imaging for medical diagnosis. Comput Med Imaging Graph (2012) 0.78
Spatial orientation mapping of fibers using polarization-sensitive second harmonic generation microscopy. J Biophotonics (2012) 0.77
Angular-interrogation attenuated total reflection metrology system for plasmonic sensors. Appl Opt (2005) 0.77
Investigation of two-photon excited fluorescence increment via crosslinked bovine serum albumin. Opt Express (2012) 0.77
Adaptive-optics system with liquid-crystal phase-shift interferometer. Appl Opt (2006) 0.77