PubRank

Tak Wah Mak

Author PubWeight™ 45.84‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas. J Clin Invest 2004 3.92
2 Lipocalin 2 is essential for chronic kidney disease progression in mice and humans. J Clin Invest 2010 2.23
3 The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis. Genes Dev 2005 2.18
4 Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination. J Exp Med 2003 2.16
5 D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes Dev 2012 2.10
6 Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice. J Clin Invest 2007 1.86
7 Keratinocyte-specific Pten deficiency results in epidermal hyperplasia, accelerated hair follicle morphogenesis and tumor formation. Cancer Res 2003 1.75
8 DJ-1/PARK7 is an important mediator of hypoxia-induced cellular responses. Proc Natl Acad Sci U S A 2009 1.71
9 PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function. Proc Natl Acad Sci U S A 2011 1.70
10 Retracted Enhanced insulin sensitivity, energy expenditure and thermogenesis in adipose-specific Pten suppression in mice. Nat Med 2004 1.69
11 Epstein-Barr virus latent membrane protein 1 activation of NF-kappaB through IRAK1 and TRAF6. Proc Natl Acad Sci U S A 2003 1.60
12 Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11. Nat Med 2011 1.52
13 TAp73 depletion accelerates aging through metabolic dysregulation. Genes Dev 2012 1.45
14 Portrait of PTEN: messages from mutant mice. Cancer Sci 2008 1.44
15 Regulation of transactivation-independent proapoptotic activity of p53 by FOXO3a. Proc Natl Acad Sci U S A 2006 1.37
16 Physiological functions of Pten in mouse tissues. Cell Struct Funct 2003 1.36
17 Hyperplasia and carcinomas in Pten-deficient mice and reduced PTEN protein in human bladder cancer patients. Cancer Res 2006 1.29
18 Pten deficiency in melanocytes results in resistance to hair graying and susceptibility to carcinogen-induced melanomagenesis. Cancer Res 2008 1.19
19 Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1). Proc Natl Acad Sci U S A 2003 1.11
20 Loss of Pten, a tumor suppressor, causes the strong inhibition of autophagy without affecting LC3 lipidation. Autophagy 2008 1.11
21 Nucleotide oligomerization domain-containing proteins instruct T cell helper type 2 immunity through stromal activation. Proc Natl Acad Sci U S A 2011 1.05
22 The Pten/PI3K pathway governs the homeostasis of Valpha14iNKT cells. Blood 2006 1.00
23 Ckap2 regulates aneuploidy, cell cycling, and cell death in a p53-dependent manner. Cancer Res 2005 1.00
24 Acidic nuclear phosphoprotein 32kDa (ANP32)B-deficient mouse reveals a hierarchy of ANP32 importance in mammalian development. Proc Natl Acad Sci U S A 2011 0.92
25 Crucial role for TNF receptor-associated factor 2 (TRAF2) in regulating NFκB2 signaling that contributes to autoimmunity. Proc Natl Acad Sci U S A 2011 0.91
26 PKM2: a gatekeeper between growth and survival. Cell Res 2011 0.90
27 TRADD contributes to tumour suppression by regulating ULF-dependent p19Arf ubiquitylation. Nat Cell Biol 2012 0.89
28 Identification of BERP (brain-expressed RING finger protein) as a p53 target gene that modulates seizure susceptibility through interacting with GABA(A) receptors. Proc Natl Acad Sci U S A 2010 0.89
29 Inhibition of apoptosome activation protects injured motor neurons from cell death. J Biol Chem 2008 0.82
30 Promoting immunity during chronic infection--the therapeutic potential of common gamma-chain cytokines. Mol Immunol 2013 0.81
31 Characterization of dsRNA-induced pancreatitis model reveals the regulatory role of IFN regulatory factor 2 (Irf2) in trypsinogen5 gene transcription. Proc Natl Acad Sci U S A 2011 0.81
32 Retracted Tumorigenesis facilitated by Pten deficiency in the skin: evidence of p53-Pten complex formation on the initiation phase. Cancer Sci 2004 0.77
33 A novel TLR2-triggered signalling crosstalk synergistically intensifies TNF-mediated IL-6 induction. J Cell Mol Med 2014 0.76