Published in Genes Dev on June 15, 2010
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Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2. Dev Cell (2009) 2.55
Loss of Klf4 in mice causes altered proliferation and differentiation and precancerous changes in the adult stomach. Gastroenterology (2005) 2.53
Foxl1-Cre-marked adult hepatic progenitors have clonogenic and bilineage differentiation potential. Genes Dev (2011) 2.53
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Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development. Genes Dev (2008) 2.38
Foxa2 regulates alveolarization and goblet cell hyperplasia. Development (2004) 2.35
The Kruppel-like factor KLF4 is a critical regulator of monocyte differentiation. EMBO J (2007) 2.34
Conditional deletion of Krüppel-like factor 4 delays downregulation of smooth muscle cell differentiation markers but accelerates neointimal formation following vascular injury. Circ Res (2008) 2.30
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The mouse Forkhead Box m1 transcription factor is essential for hepatoblast mitosis and development of intrahepatic bile ducts and vessels during liver morphogenesis. Dev Biol (2004) 2.19
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Foxa2 integrates the transcriptional response of the hepatocyte to fasting. Cell Metab (2005) 2.15
Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis. J Biol Chem (2005) 2.15
Sox17 regulates organ lineage segregation of ventral foregut progenitor cells. Dev Cell (2009) 2.14
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Foxa2 is essential for mouse endometrial gland development and fertility. Biol Reprod (2010) 2.12
Foxa1 and Foxa2 are essential for sexual dimorphism in liver cancer. Cell (2012) 2.05
Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon. Gastroenterology (2006) 2.04
Foxa2 and H2A.Z mediate nucleosome depletion during embryonic stem cell differentiation. Cell (2012) 2.02
Expansion of adult beta-cell mass in response to increased metabolic demand is dependent on HNF-4alpha. Genes Dev (2007) 1.97
MicroRNAs control intestinal epithelial differentiation, architecture, and barrier function. Gastroenterology (2010) 1.95
Elevated mouse hepatic betatrophin expression does not increase human β-cell replication in the transplant setting. Diabetes (2013) 1.90
Foxa2 is required for the differentiation of pancreatic alpha-cells. Dev Biol (2005) 1.90
The transcriptional response of the islet to pregnancy in mice. Mol Endocrinol (2009) 1.89
Pancreatic beta cells require NeuroD to achieve and maintain functional maturity. Cell Metab (2010) 1.88
FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis. Development (2010) 1.86
Foxl1 is a marker of bipotential hepatic progenitor cells in mice. Hepatology (2009) 1.82
Expansion of beta-cell mass in response to pregnancy. Trends Endocrinol Metab (2009) 1.81
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The pluripotency factor LIN28 marks undifferentiated spermatogonia in mouse. BMC Dev Biol (2009) 1.66
FoxOs function synergistically to promote glucose production. J Biol Chem (2010) 1.66
Foxa2 controls vesicle docking and insulin secretion in mature Beta cells. Cell Metab (2007) 1.66
Defining pancreatic endocrine precursors and their descendants. Diabetes (2007) 1.65
Conditional deletion of the mouse Klf4 gene results in corneal epithelial fragility, stromal edema, and loss of conjunctival goblet cells. Mol Cell Biol (2006) 1.63
Foxa2 controls Pdx1 gene expression in pancreatic beta-cells in vivo. Diabetes (2002) 1.60
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Resetting the transcription factor network reverses terminal chronic hepatic failure. J Clin Invest (2015) 1.58
Foxa2 is required for transition to air breathing at birth. Proc Natl Acad Sci U S A (2004) 1.57
Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress. Nat Med (2008) 1.57
Foxa2 regulates multiple pathways of insulin secretion. J Clin Invest (2004) 1.57
Postprandial hepatic lipid metabolism requires signaling through Akt2 independent of the transcription factors FoxA2, FoxO1, and SREBP1c. Cell Metab (2011) 1.55
CRTC2 (TORC2) contributes to the transcriptional response to fasting in the liver but is not required for the maintenance of glucose homeostasis. Cell Metab (2009) 1.55
The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice. J Clin Invest (2009) 1.54
Genome-wide analysis of histone modifications in human pancreatic islets. Genome Res (2010) 1.51
An FGF response pathway that mediates hepatic gene induction in embryonic endoderm cells. Dev Cell (2006) 1.50
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Foxa1 and Foxa2 maintain the metabolic and secretory features of the mature beta-cell. Mol Endocrinol (2010) 1.47
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Orthogonal analysis of C/EBPbeta targets in vivo during liver proliferation. Proc Natl Acad Sci U S A (2004) 1.46
Cis-regulatory modules in the mammalian liver: composition depends on strength of Foxa2 consensus site. Nucleic Acids Res (2008) 1.46
Identification of transcriptional networks during liver regeneration. J Biol Chem (2004) 1.46
beta-Catenin is critical for early postnatal liver growth. Am J Physiol Gastrointest Liver Physiol (2007) 1.45
Transcriptional networks in the liver: hepatocyte nuclear factor 6 function is largely independent of Foxa2. Mol Cell Biol (2005) 1.45
FoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestine. J Biol Chem (2008) 1.44
Foxa1 and Foxa2 regulate bile duct development in mice. J Clin Invest (2009) 1.43
Regeneration of pancreatic islets after partial pancreatectomy in mice does not involve the reactivation of neurogenin-3. Diabetes (2005) 1.38
Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity. PLoS Genet (2013) 1.37
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HNF-4alpha: from MODY to late-onset type 2 diabetes. Trends Mol Med (2004) 1.32
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DNA methylation is required for the control of stem cell differentiation in the small intestine. Genes Dev (2014) 1.31
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Foxa1 and Foxa2 control the differentiation of goblet and enteroendocrine L- and D-cells in mice. Gastroenterology (2009) 1.28
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Characterization of pancreatic transcription factor Pdx-1 binding sites using promoter microarray and serial analysis of chromatin occupancy. J Biol Chem (2007) 1.21
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